Phosphoramidate derivatives of d4T with improved anti-HIV efficacy retain fullactivity in thymidine kinase-deficient cells

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 10, 1996, Pages 1183-1186

  McGuigan, Christopher ^a   Cahard, Dominique ^a   Sheeka, Hendrika M ^b   De Clercq, Erik ^c   Balzarini, Jan ^c  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; PHOSPHORAMIDIC ACID DERIVATIVE; STAVUDINE; THYMIDINE KINASE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG ACTIVATION; DRUG EFFICACY; DRUG POTENCY; DRUG STABILITY; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PHOSPHORYLATION; STEREOCHEMISTRY;

EID: 0030053172     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00195-3     Document Type: Article

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