-
1
-
-
0031897632
-
-KB and Rel proteins: Evolutionarily conserved mediators of immune responses
-
-KB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol. 1998;16:225-260.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
4
-
-
0036781052
-
-KB regulation in the immune system
-
-KB regulation in the immune system. Nat Rev Immunol. 2002;2:725-734.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
5
-
-
0033626350
-
-KB transcription factors: Key mediators of B-cell activation
-
-KB transcription factors: key mediators of B-cell activation. Immunol Rev. 2000;176:134-140.
-
(2000)
Immunol Rev
, vol.176
, pp. 134-140
-
-
Gugasyan, R.1
Grumont, R.2
Grossmann, M.3
-
9
-
-
0034423508
-
The antiapoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression
-
Grossmann M, O'Reilly LA, Gugasyan R, Strasser A, Adams JM, Gerondakis S. The antiapoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression. EMBO J. 2000;19:6351-6360.
-
(2000)
EMBO J
, vol.19
, pp. 6351-6360
-
-
Grossmann, M.1
O'Reilly, L.A.2
Gugasyan, R.3
Strasser, A.4
Adams, J.M.5
Gerondakis, S.6
-
11
-
-
0037374815
-
The role of PI3K in immune cells
-
Koyasu S. The role of PI3K in immune cells. Nat Immunol. 2003;4:313-319.
-
(2003)
Nat Immunol
, vol.4
, pp. 313-319
-
-
Koyasu, S.1
-
12
-
-
16244393685
-
Signalling by PI3K isoforms: Insights from gene-targeted mice
-
Vanhaesebroeck B, Ali K, Bilancio A, Geering B, Foukas LC. Signalling by PI3K isoforms: insights from gene-targeted mice. Trends Biochem Sci. 2005;30:194-204.
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 194-204
-
-
Vanhaesebroeck, B.1
Ali, K.2
Bilancio, A.3
Geering, B.4
Foukas, L.C.5
-
13
-
-
0033555829
-
Xid-like immunodeficiency in mice with disruption of the p85α subunit of phosphoinositide 3-kinase
-
Suzuki H, Terauchi Y, Fujiwara M, et al. Xid-like immunodeficiency in mice with disruption of the p85α subunit of phosphoinositide 3-kinase. Science. 1999;283:390-392.
-
(1999)
Science
, vol.283
, pp. 390-392
-
-
Suzuki, H.1
Terauchi, Y.2
Fujiwara, M.3
-
15
-
-
0033959733
-
BLNK: Connecting Syk and Btk to calcium signals
-
Kurosaki T, Tsukada S. BLNK: connecting Syk and Btk to calcium signals. Immunity. 2000;12: 1-5.
-
(2000)
Immunity
, vol.12
, pp. 1-5
-
-
Kurosaki, T.1
Tsukada, S.2
-
16
-
-
0036344276
-
-KB kinase lipid raft recruitment and activation in response to BCR signaling
-
-KB kinase lipid raft recruitment and activation in response to BCR signaling. Nat Immunol. 2002;3: 780-786.
-
(2002)
Nat Immunol
, vol.3
, pp. 780-786
-
-
Su, T.T.1
Guo, B.2
Kawakami, Y.3
-
19
-
-
0037341617
-
PI3K and Btk differentially regulate B cell antigen receptormediated signal transduction
-
Suzuki H, Matsuda S, Terauchi Y, et al. PI3K and Btk differentially regulate B cell antigen receptormediated signal transduction. Nat Immunol. 2003;4:280-286.
-
(2003)
Nat Immunol
, vol.4
, pp. 280-286
-
-
Suzuki, H.1
Matsuda, S.2
Terauchi, Y.3
-
22
-
-
0033559321
-
Involvement of wiskott-aldrich syndrome protein in B-cell cytoplasmic tyrosine kinase pathway
-
Baba Y, Nonoyama S, Matsushita M, et al. Involvement of wiskott-aldrich syndrome protein in B-cell cytoplasmic tyrosine kinase pathway. Blood. 1999;93:2003-2012.
-
(1999)
Blood
, vol.93
, pp. 2003-2012
-
-
Baba, Y.1
Nonoyama, S.2
Matsushita, M.3
-
23
-
-
0024425432
-
Oncogenes, growth factors, and signal transduction
-
Druker BJ, Mamon HJ, Roberts TM. Oncogenes, growth factors, and signal transduction. N Engl J Med. 1989;321:1383-1391.
-
(1989)
N Engl J Med
, vol.321
, pp. 1383-1391
-
-
Druker, B.J.1
Mamon, H.J.2
Roberts, T.M.3
-
24
-
-
0031666744
-
Development of a self-inactivating lentivirus vector
-
Miyoshi H, Blomer U, Takahashi M, Gage FH, Verma IM. Development of a self-inactivating lentivirus vector. J Virol. 1998;72:8150-8157.
-
(1998)
J Virol
, vol.72
, pp. 8150-8157
-
-
Miyoshi, H.1
Blomer, U.2
Takahashi, M.3
Gage, F.H.4
Verma, I.M.5
-
25
-
-
19244372556
-
Deficient expression of Bruton's tyrosine kinase in monocytes from X-linked agammaglobulinemia as evaluated by a flow cytometric analysis and its clinical application to carrier detection
-
Futatani T, Miyawaki T, Tsukada S, et al. Deficient expression of Bruton's tyrosine kinase in monocytes from X-linked agammaglobulinemia as evaluated by a flow cytometric analysis and its clinical application to carrier detection. Blood. 1998;91:595-602.
-
(1998)
Blood
, vol.91
, pp. 595-602
-
-
Futatani, T.1
Miyawaki, T.2
Tsukada, S.3
-
26
-
-
24944456875
-
Protein misfolding, aggregation, and degradation in disease
-
Gregersen N, Bolund L, Bross P. Protein misfolding, aggregation, and degradation in disease. Mol Biotechnol. 2005;31:141-150.
-
(2005)
Mol Biotechnol
, vol.31
, pp. 141-150
-
-
Gregersen, N.1
Bolund, L.2
Bross, P.3
-
27
-
-
0033520933
-
Temperature-sensitive ZAP70 mutants degrading through a proteasome-independent pathway: Restoration of a kinase domain mutant by Cdc37
-
Matsuda S, Suzuki-Fujimoto T, Minowa A, Ueno H, Katamura K, Koyasu S. Temperature-sensitive ZAP70 mutants degrading through a proteasome-independent pathway: restoration of a kinase domain mutant by Cdc37. J Biol Chem. 1999;274:34515-34518.
-
(1999)
J Biol Chem
, vol.274
, pp. 34515-34518
-
-
Matsuda, S.1
Suzuki-Fujimoto, T.2
Minowa, A.3
Ueno, H.4
Katamura, K.5
Koyasu, S.6
-
28
-
-
0035892228
-
Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation
-
Allman D, Lindsley RC, DeMuth W, Rudd K, Shinton SA, Hardy RR. Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation. J Immunol. 2001;167:6834-6840.
-
(2001)
J Immunol
, vol.167
, pp. 6834-6840
-
-
Allman, D.1
Lindsley, R.C.2
DeMuth, W.3
Rudd, K.4
Shinton, S.A.5
Hardy, R.R.6
-
29
-
-
0033526816
-
B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals
-
Loder F, Mutschler B, Ray RJ, et al. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J Exp Med. 1999;190: 75-89.
-
(1999)
J Exp Med
, vol.190
, pp. 75-89
-
-
Loder, F.1
Mutschler, B.2
Ray, R.J.3
-
30
-
-
0036498795
-
Transitional B lymphocyte subsets operate as distinct checkpoints in murine splenic B cell development
-
Su TT, Rawlings DJ. Transitional B lymphocyte subsets operate as distinct checkpoints in murine splenic B cell development. J Immunol. 2002;168: 2101-2110.
-
(2002)
J Immunol
, vol.168
, pp. 2101-2110
-
-
Su, T.T.1
Rawlings, D.J.2
-
31
-
-
0037827638
-
Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis
-
Jun JE, Wilson LE, Vinuesa CG, et al. Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis. Immunity. 2003;18:751-762.
-
(2003)
Immunity
, vol.18
, pp. 751-762
-
-
Jun, J.E.1
Wilson, L.E.2
Vinuesa, C.G.3
-
32
-
-
0037490078
-
The MAGUK family protein CARD11 is essential for lymphocyte activation
-
Hara H, Wada T, Bakal C, et al. The MAGUK family protein CARD11 is essential for lymphocyte activation. Immunity. 2003;18:763-775.
-
(2003)
Immunity
, vol.18
, pp. 763-775
-
-
Hara, H.1
Wada, T.2
Bakal, C.3
-
33
-
-
0041381357
-
Defective development and function of Bc110-deficient follicular, marginal zone and B1 B cells
-
Xue L, Morris SW, Orihuela C, et al. Defective development and function of Bc110-deficient follicular, marginal zone and B1 B cells. Nat Immunol. 2003;4:857-865.
-
(2003)
Nat Immunol
, vol.4
, pp. 857-865
-
-
Xue, L.1
Morris, S.W.2
Orihuela, C.3
-
34
-
-
0345374583
-
-KB-dependent lymphocyte activation and development by paracaspase
-
-KB-dependent lymphocyte activation and development by paracaspase. Science. 2003;302:1581-1584.
-
(2003)
Science
, vol.302
, pp. 1581-1584
-
-
Ruefli-Brasse, A.A.1
French, D.M.2
Dixit, V.M.3
-
35
-
-
10844255780
-
Altered splenic B cell subset development in mice lacking phosphoinositide 3-kinase p85α
-
Donahue AC, Hess KL, Ng KL, Fruman DA. Altered splenic B cell subset development in mice lacking phosphoinositide 3-kinase p85α. Int Immunol. 2004;16:1789-1798.
-
(2004)
Int Immunol
, vol.16
, pp. 1789-1798
-
-
Donahue, A.C.1
Hess, K.L.2
Ng, K.L.3
Fruman, D.A.4
-
36
-
-
0347593996
-
Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase cΓ2 to Ras in B cell receptor signaling
-
Oh-hora M, Johmura S, Hashimoto A, Hikida M, Kurosaki T. Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase cΓ2 to Ras in B cell receptor signaling. J Exp Med. 2003;198:1841-1851.
-
(2003)
J Exp Med
, vol.198
, pp. 1841-1851
-
-
Oh-hora, M.1
Johmura, S.2
Hashimoto, A.3
Hikida, M.4
Kurosaki, T.5
-
37
-
-
17944377368
-
PKCβ modulates antigen receptor signaling via regulation of Btk membrane localization
-
Kang SW, Wahl MI, Chu J, et al. PKCβ modulates antigen receptor signaling via regulation of Btk membrane localization. EMBO J. 2001;20:5692-5702.
-
(2001)
EMBO J
, vol.20
, pp. 5692-5702
-
-
Kang, S.W.1
Wahl, M.I.2
Chu, J.3
-
38
-
-
0029150389
-
Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression
-
Köntgen F, Grumont RJ, Strasser A, et al. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. Genes Dev. 1995;9: 1965-1977.
-
(1995)
Genes Dev
, vol.9
, pp. 1965-1977
-
-
Köntgen, F.1
Grumont, R.J.2
Strasser, A.3
-
39
-
-
0031738699
-
Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity
-
Rolink AG, Andersson J, Melchers F. Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity. Eur J Immunol. 1998;28:3738-3748.
-
(1998)
Eur J Immunol
, vol.28
, pp. 3738-3748
-
-
Rolink, A.G.1
Andersson, J.2
Melchers, F.3
-
40
-
-
0033103016
-
Negative selection of immature B cells by receptor editing or deletion is determined by site of antigen encounter
-
Sandel PC, Monroe JG. Negative selection of immature B cells by receptor editing or deletion is determined by site of antigen encounter. Immunity. 1999;10:289-299.
-
(1999)
Immunity
, vol.10
, pp. 289-299
-
-
Sandel, P.C.1
Monroe, J.G.2
-
41
-
-
27844469655
-
-
Vá rnai P, Bondeva T, Tamas P, et al. Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners. J Cell Sci. 2005;118:4879-4888.
-
Vá rnai P, Bondeva T, Tamas P, et al. Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners. J Cell Sci. 2005;118:4879-4888.
-
-
-
-
42
-
-
2942582913
-
Survival of resting mature B lymphocytes depends on BCR signaling via the Igα/β heterodimer
-
Kraus M, Alimzhanov MB, Rajewsky N, Rajewsky K. Survival of resting mature B lymphocytes depends on BCR signaling via the Igα/β heterodimer. Cell. 2004;117:787-800.
-
(2004)
Cell
, vol.117
, pp. 787-800
-
-
Kraus, M.1
Alimzhanov, M.B.2
Rajewsky, N.3
Rajewsky, K.4
-
43
-
-
0038671744
-
BCR targets cyclin D2 via Btk and the p85α subunit of PI3K to induce cell cycle progression in primary mouse B cells
-
Glassford J, Soeiro I, Skarell SM, et al. BCR targets cyclin D2 via Btk and the p85α subunit of PI3K to induce cell cycle progression in primary mouse B cells. Oncogene. 2003;22:2248-2259.
-
(2003)
Oncogene
, vol.22
, pp. 2248-2259
-
-
Glassford, J.1
Soeiro, I.2
Skarell, S.M.3
-
44
-
-
0041695162
-
Contribution of BCAP to maintenance of mature B cells through c-Rel
-
Yamazaki T, Kurosaki T. Contribution of BCAP to maintenance of mature B cells through c-Rel. Nat Immunol. 2003;4:780-786.
-
(2003)
Nat Immunol
, vol.4
, pp. 780-786
-
-
Yamazaki, T.1
Kurosaki, T.2
-
45
-
-
2342622123
-
Optimal B cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors
-
Yusuf I, Zhu X, Kharas MG, Chen J, Fruman DA. Optimal B cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors. Blood. 2004;104:784-787.
-
(2004)
Blood
, vol.104
, pp. 784-787
-
-
Yusuf, I.1
Zhu, X.2
Kharas, M.G.3
Chen, J.4
Fruman, D.A.5
-
46
-
-
4043082729
-
Cutting edge: Differential roles for phosphoinositide 3-kinases, p110γand p110β, in lymphocyte chemotaxis and homing
-
Reif K, Okkenhaug K, Sasaki T, et al. Cutting edge: differential roles for phosphoinositide 3-kinases, p110γand p110β, in lymphocyte chemotaxis and homing. J Immunol. 2004;173:2236-2240.
-
(2004)
J Immunol
, vol.173
, pp. 2236-2240
-
-
Reif, K.1
Okkenhaug, K.2
Sasaki, T.3
-
47
-
-
0033128166
-
Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages
-
Vanhaesebroeck B, Jones GE, Allen WE, et al. Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages. Nat Cell Biol. 1999;1:69-71.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 69-71
-
-
Vanhaesebroeck, B.1
Jones, G.E.2
Allen, W.E.3
|