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Volumn 30, Issue 13, 2009, Pages 2531-2543

Human hepatocyte functions in a crossed hollow fiber membrane bioreactor

Author keywords

Diazepam biotransformation; Hepatocytes; Hollow fiber; Liver functions; Mass transport; Membrane bioreactor

Indexed keywords

DIAZEPAM BIOTRANSFORMATION; HEPATOCYTES; HOLLOW FIBER; MASS TRANSPORT; MEMBRANE BIOREACTOR;

EID: 60849101048     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.01.011     Document Type: Article
Times cited : (99)

References (49)
  • 1
    • 1542274273 scopus 로고    scopus 로고
    • Kluwer Academic Publishers, Dordrecht, Boston, London p. 365-85
    • Berry M.N., and Edwards A.M. The hepatocyte review (2000), Kluwer Academic Publishers, Dordrecht, Boston, London p. 365-85
    • (2000) The hepatocyte review
    • Berry, M.N.1    Edwards, A.M.2
  • 3
    • 0025870255 scopus 로고
    • Co-cultures of hepatocytes with epithelial-like cell lines: expression of drug biotransformation activities by hepatocytes
    • Donato M.T., Castell J.V., and Gomez-Lechon M.J. Co-cultures of hepatocytes with epithelial-like cell lines: expression of drug biotransformation activities by hepatocytes. Cell Biol Toxicol 7 (1991) 1-14
    • (1991) Cell Biol Toxicol , vol.7 , pp. 1-14
    • Donato, M.T.1    Castell, J.V.2    Gomez-Lechon, M.J.3
  • 4
    • 0026158432 scopus 로고
    • Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration
    • Dunn J.C., Tompkins R.G., and Yarmush M.L. Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration. Biotechnol Prog 7 (1991) 237-245
    • (1991) Biotechnol Prog , vol.7 , pp. 237-245
    • Dunn, J.C.1    Tompkins, R.G.2    Yarmush, M.L.3
  • 5
    • 52449126871 scopus 로고    scopus 로고
    • Transportation of transplantable cell sheets fabricated with temperature-responsive culture surfaces for regenerative medicine
    • Nozaki T., Yamato M., Nishida K., and Okano T. Transportation of transplantable cell sheets fabricated with temperature-responsive culture surfaces for regenerative medicine. J Tissue Eng Regen Med 2 (2008) 190-195
    • (2008) J Tissue Eng Regen Med , vol.2 , pp. 190-195
    • Nozaki, T.1    Yamato, M.2    Nishida, K.3    Okano, T.4
  • 6
    • 35348949492 scopus 로고    scopus 로고
    • Mass transfer and metabolic reactions in hepatocyte spheroids cultured in rotating wall gas-permeable membrane system
    • Curcio E., Salerno S., Barbieri G., De Bartolo L., Drioli E., and Bader A. Mass transfer and metabolic reactions in hepatocyte spheroids cultured in rotating wall gas-permeable membrane system. Biomaterials 28 (2007) 5487-5497
    • (2007) Biomaterials , vol.28 , pp. 5487-5497
    • Curcio, E.1    Salerno, S.2    Barbieri, G.3    De Bartolo, L.4    Drioli, E.5    Bader, A.6
  • 8
    • 0036133009 scopus 로고    scopus 로고
    • Perfusion culture of hepatocytes within galactose-derivatized biodegradable poly(lactide-co-glycolide) scaffolds prepared by gas foaming of effervescent salts
    • Park T.G. Perfusion culture of hepatocytes within galactose-derivatized biodegradable poly(lactide-co-glycolide) scaffolds prepared by gas foaming of effervescent salts. J Biomed Mater Res 59 (2002) 127-135
    • (2002) J Biomed Mater Res , vol.59 , pp. 127-135
    • Park, T.G.1
  • 9
    • 0034861615 scopus 로고    scopus 로고
    • Advance in bioartificial liver devices
    • Allen J.W., Hassanein T., and Bathia S.N. Advance in bioartificial liver devices. Hepatology 34 (2001) 447-455
    • (2001) Hepatology , vol.34 , pp. 447-455
    • Allen, J.W.1    Hassanein, T.2    Bathia, S.N.3
  • 10
    • 18244406583 scopus 로고    scopus 로고
    • A bioartificial liver - state of the art
    • Strain A.J., and Neuberger J.M. A bioartificial liver - state of the art. Science 295 (2002) 1005-1009
    • (2002) Science , vol.295 , pp. 1005-1009
    • Strain, A.J.1    Neuberger, J.M.2
  • 11
    • 38449113028 scopus 로고    scopus 로고
    • Radial flow hepatocyte bioreactor using stacked microfabricated grooved substrates
    • Park J., Li Y., Berthiaume F., Toner M., Yarmush M.L., and Tilles A.W. Radial flow hepatocyte bioreactor using stacked microfabricated grooved substrates. Biotechnol Bioeng 99 2 (2008) 455-467
    • (2008) Biotechnol Bioeng , vol.99 , Issue.2 , pp. 455-467
    • Park, J.1    Li, Y.2    Berthiaume, F.3    Toner, M.4    Yarmush, M.L.5    Tilles, A.W.6
  • 12
    • 0036019367 scopus 로고    scopus 로고
    • Functional behaviour of primary rat liver cells in a three-dimensional perfused microarray bioreactor
    • Powers M.J., Janigian D.M., Wack K.E., Baker C.S., Beer Stolz D., and Griffith L.G. Functional behaviour of primary rat liver cells in a three-dimensional perfused microarray bioreactor. Tissue Eng 8 (2002) 499-513
    • (2002) Tissue Eng , vol.8 , pp. 499-513
    • Powers, M.J.1    Janigian, D.M.2    Wack, K.E.3    Baker, C.S.4    Beer Stolz, D.5    Griffith, L.G.6
  • 13
    • 33845386789 scopus 로고    scopus 로고
    • Development and characterization of a small-scale bioreactor based on a bioartificial hepatic culture model for predictive pharmacological in vitro screenings
    • Schmitmeier S., Langsch A., Jasmund I., and Bader A. Development and characterization of a small-scale bioreactor based on a bioartificial hepatic culture model for predictive pharmacological in vitro screenings. Biotech Bioeng 95/6 (2006) 1198-1206
    • (2006) Biotech Bioeng , vol.95-6 , pp. 1198-1206
    • Schmitmeier, S.1    Langsch, A.2    Jasmund, I.3    Bader, A.4
  • 14
    • 18144411700 scopus 로고    scopus 로고
    • Diffusive and convective transport through hollow fiber membranes for liver cell culture
    • Curcio E., De Bartolo L., Barbieri G., Rende M., Giorno L., Morelli S., et al. Diffusive and convective transport through hollow fiber membranes for liver cell culture. J Biotechnol 117 (2005) 309-321
    • (2005) J Biotechnol , vol.117 , pp. 309-321
    • Curcio, E.1    De Bartolo, L.2    Barbieri, G.3    Rende, M.4    Giorno, L.5    Morelli, S.6
  • 15
    • 23644448920 scopus 로고    scopus 로고
    • Bioreactors for tissue mass culture: design, characterisation, and recent advances
    • Martin Y., and Vermett P. Bioreactors for tissue mass culture: design, characterisation, and recent advances. Biomaterials 26 (2005) 7481-7503
    • (2005) Biomaterials , vol.26 , pp. 7481-7503
    • Martin, Y.1    Vermett, P.2
  • 16
    • 0030741849 scopus 로고    scopus 로고
    • In vitro evaluation of a novel bioreactor based on an integral oxygenator and a spirally wound nonwoven polyester matrix for hepatocyte culture as small aggregates
    • Flendrig L.M., La Soe J.W., Joerning G.G.A., Steenbeck A., Karlsen O.T., Bovée W.M.M., et al. In vitro evaluation of a novel bioreactor based on an integral oxygenator and a spirally wound nonwoven polyester matrix for hepatocyte culture as small aggregates. J Hepatol 26 (1997) 1379-1392
    • (1997) J Hepatol , vol.26 , pp. 1379-1392
    • Flendrig, L.M.1    La Soe, J.W.2    Joerning, G.G.A.3    Steenbeck, A.4    Karlsen, O.T.5    Bovée, W.M.M.6
  • 17
  • 19
    • 0027392765 scopus 로고
    • Evaluation of a hepatocyte-entrapment hollow fiber bioreactor: a potential bioartificial liver
    • Nyberg S.L., Shatford R.A., Peshwa M.W., White J.G., Cerra F.B., and Hu W.S. Evaluation of a hepatocyte-entrapment hollow fiber bioreactor: a potential bioartificial liver. Biotechnol Bioeng 41 (1992) 194-203
    • (1992) Biotechnol Bioeng , vol.41 , pp. 194-203
    • Nyberg, S.L.1    Shatford, R.A.2    Peshwa, M.W.3    White, J.G.4    Cerra, F.B.5    Hu, W.S.6
  • 20
    • 0035680559 scopus 로고    scopus 로고
    • Advances in bioartificial liver assist devices
    • Patzer J.F. Advances in bioartificial liver assist devices. Ann N Y Acad Sci 944 (2001) 320-333
    • (2001) Ann N Y Acad Sci , vol.944 , pp. 320-333
    • Patzer, J.F.1
  • 21
    • 0033956082 scopus 로고    scopus 로고
    • A novel full-scale flat membrane bioreactor utilizing porcine hepatocytes: cell viability and tissue-specific functions
    • De Bartolo L., Jarosch-Von Schweder G., Haverich A., and Bader A. A novel full-scale flat membrane bioreactor utilizing porcine hepatocytes: cell viability and tissue-specific functions. Biotechnol Prog 16 (2000) 102-108
    • (2000) Biotechnol Prog , vol.16 , pp. 102-108
    • De Bartolo, L.1    Jarosch-Von Schweder, G.2    Haverich, A.3    Bader, A.4
  • 22
    • 0026547439 scopus 로고
    • Hepatocytes in collagen sandwich: evidence for transcriptional and translational regulation
    • Dunn J.C., Tompkins R.G., and Yarmush M.L. Hepatocytes in collagen sandwich: evidence for transcriptional and translational regulation. J Cell Biol 116 (1992) 1043-1053
    • (1992) J Cell Biol , vol.116 , pp. 1043-1053
    • Dunn, J.C.1    Tompkins, R.G.2    Yarmush, M.L.3
  • 23
    • 0343415085 scopus 로고    scopus 로고
    • Fibronectin regulates morphology, cell organization and gene expression of rat fetal hepatocytes in primary culture
    • Sanchez A., Alvarez Pagan R., Roncero C., Vilaro S., Benito M., and Fabregat I. Fibronectin regulates morphology, cell organization and gene expression of rat fetal hepatocytes in primary culture. J Hepatol 32 2 (2000) 242-250
    • (2000) J Hepatol , vol.32 , Issue.2 , pp. 242-250
    • Sanchez, A.1    Alvarez Pagan, R.2    Roncero, C.3    Vilaro, S.4    Benito, M.5    Fabregat, I.6
  • 24
    • 31044436305 scopus 로고    scopus 로고
    • Galactosylated poly(vinylidene difluoride) hollow fiber bioreactor for hepatocyte culture
    • Lu H.-F., Lim W.S., Zhang P.C., Chia S.M., Yu H., Mao H.Q., et al. Galactosylated poly(vinylidene difluoride) hollow fiber bioreactor for hepatocyte culture. Tissue Eng 11 (2005) 1667-1677
    • (2005) Tissue Eng , vol.11 , pp. 1667-1677
    • Lu, H.-F.1    Lim, W.S.2    Zhang, P.C.3    Chia, S.M.4    Yu, H.5    Mao, H.Q.6
  • 25
    • 13444266249 scopus 로고    scopus 로고
    • Biotransformation and liver specific functions of human hepatocytes in culture on RGD-immobilised plasma-processed membranes
    • De Bartolo L., Morelli S., Lopez L., Giorno L., Campana C., Salerno S., et al. Biotransformation and liver specific functions of human hepatocytes in culture on RGD-immobilised plasma-processed membranes. Biomaterials 26 21 (2005) 4432-4441
    • (2005) Biomaterials , vol.26 , Issue.21 , pp. 4432-4441
    • De Bartolo, L.1    Morelli, S.2    Lopez, L.3    Giorno, L.4    Campana, C.5    Salerno, S.6
  • 26
    • 0034534211 scopus 로고    scopus 로고
    • Functional evaluation of poly-(N-p-vinylbenzyl-O-b-d-galactopyranosyl-[1-4]-d-gluconamide) (PVLA) as a liver specific carrier
    • Watanabe Y., Liu X., Shibuya I., and Akaike T. Functional evaluation of poly-(N-p-vinylbenzyl-O-b-d-galactopyranosyl-[1-4]-d-gluconamide) (PVLA) as a liver specific carrier. J Biomater Sci Polym Ed 11 (2000) 833-848
    • (2000) J Biomater Sci Polym Ed , vol.11 , pp. 833-848
    • Watanabe, Y.1    Liu, X.2    Shibuya, I.3    Akaike, T.4
  • 27
    • 0036010380 scopus 로고    scopus 로고
    • Evaluation of cell behaviour related to physico-chemical properties of polymeric membranes to be used in bioartificial organs
    • De Bartolo L., Morelli S., Bader A., and Drioli E. Evaluation of cell behaviour related to physico-chemical properties of polymeric membranes to be used in bioartificial organs. Biomaterials 23 12 (2002) 2485-2497
    • (2002) Biomaterials , vol.23 , Issue.12 , pp. 2485-2497
    • De Bartolo, L.1    Morelli, S.2    Bader, A.3    Drioli, E.4
  • 28
    • 0036010375 scopus 로고    scopus 로고
    • Membranes for biohybrid liver support systems - investigations on hepatocyte attachment, morphology and growth
    • Krasteva N., Harms U., Albrecht W., Seifert B., Hopp M., Altankov G., et al. Membranes for biohybrid liver support systems - investigations on hepatocyte attachment, morphology and growth. Biomaterials 23 (2002) 2467-2478
    • (2002) Biomaterials , vol.23 , pp. 2467-2478
    • Krasteva, N.1    Harms, U.2    Albrecht, W.3    Seifert, B.4    Hopp, M.5    Altankov, G.6
  • 29
    • 0033011990 scopus 로고    scopus 로고
    • The effect of surface roughness of microporous membranes on the kinetics of oxygen consumption and ammonia elimination by adherent hepatocytes
    • De Bartolo L., Catapano G., Della Volpe C., and Drioli E. The effect of surface roughness of microporous membranes on the kinetics of oxygen consumption and ammonia elimination by adherent hepatocytes. J Biomater Sci Polym Ed 10 6 (1999) 641-655
    • (1999) J Biomater Sci Polym Ed , vol.10 , Issue.6 , pp. 641-655
    • De Bartolo, L.1    Catapano, G.2    Della Volpe, C.3    Drioli, E.4
  • 30
    • 1542358698 scopus 로고    scopus 로고
    • New modified polyetheretherketone membrane for liver cell culture in biohybrid systems: adhesion and specific functions of isolated hepatocytes
    • De Bartolo L., Morelli S., Rende M., Gordano A., and Drioli E. New modified polyetheretherketone membrane for liver cell culture in biohybrid systems: adhesion and specific functions of isolated hepatocytes. Biomaterials 25 (2004) 3621-3629
    • (2004) Biomaterials , vol.25 , pp. 3621-3629
    • De Bartolo, L.1    Morelli, S.2    Rende, M.3    Gordano, A.4    Drioli, E.5
  • 31
    • 0025539299 scopus 로고
    • Analysis of the structure-determining process of phase inversion membranes
    • Kimmerle K., and Strathmann H. Analysis of the structure-determining process of phase inversion membranes. Desalination 79 (1990) 283-302
    • (1990) Desalination , vol.79 , pp. 283-302
    • Kimmerle, K.1    Strathmann, H.2
  • 34
    • 0033769743 scopus 로고    scopus 로고
    • Diazepam metabolism and albumin secretion of porcine hepatocytes in collagen-sandwich after cryopreservation
    • Karim N., Allmeling C., Hengstler J.-G., Haverich A., and Bader A. Diazepam metabolism and albumin secretion of porcine hepatocytes in collagen-sandwich after cryopreservation. Biotechnol Lett 22 (2000) 1647-1652
    • (2000) Biotechnol Lett , vol.22 , pp. 1647-1652
    • Karim, N.1    Allmeling, C.2    Hengstler, J.-G.3    Haverich, A.4    Bader, A.5
  • 35
    • 0034714125 scopus 로고    scopus 로고
    • High level benzodiazepine and ammonia clearance by flat membrane bioreactors with porcine liver cells
    • Bader A., De Bartolo L., and Haverich A. High level benzodiazepine and ammonia clearance by flat membrane bioreactors with porcine liver cells. J Biotechnol 81 2-3 (2000) 95-105
    • (2000) J Biotechnol , vol.81 , Issue.2-3 , pp. 95-105
    • Bader, A.1    De Bartolo, L.2    Haverich, A.3
  • 36
    • 1042277975 scopus 로고    scopus 로고
    • Influence of flow conditions and matrix coatings on growth and differentiation of three-dimensionally cultured rat hepatocytes
    • Fiegel H.C., Havers J., Kneser U., Smith M.K., Moeller T., Kluth D., et al. Influence of flow conditions and matrix coatings on growth and differentiation of three-dimensionally cultured rat hepatocytes. Tissue Eng 10 (2004) 165-174
    • (2004) Tissue Eng , vol.10 , pp. 165-174
    • Fiegel, H.C.1    Havers, J.2    Kneser, U.3    Smith, M.K.4    Moeller, T.5    Kluth, D.6
  • 37
    • 0032721936 scopus 로고    scopus 로고
    • Effect of cell-cell interactions in preservation of cellular phenotype: co-cultivation of hepatocytes and nonparenchymal cells
    • Bathia S.N., Balis U.J., Yarmush M.L., and Toner M. Effect of cell-cell interactions in preservation of cellular phenotype: co-cultivation of hepatocytes and nonparenchymal cells. FASEB J 13 (1999) 1883-1900
    • (1999) FASEB J , vol.13 , pp. 1883-1900
    • Bathia, S.N.1    Balis, U.J.2    Yarmush, M.L.3    Toner, M.4
  • 38
    • 0037167843 scopus 로고    scopus 로고
    • Survival in three dimensions
    • Yamada K.M., and Clark K. Survival in three dimensions. Nature 419 (2002) 790-791
    • (2002) Nature , vol.419 , pp. 790-791
    • Yamada, K.M.1    Clark, K.2
  • 39
    • 0026769067 scopus 로고
    • Switching from differentiation to growth in hepatocytes: control by extracellular matrix
    • Mooney D.J., Hansen L., Vacanti J.P., Langer R., Farmer S., and Ingber D. Switching from differentiation to growth in hepatocytes: control by extracellular matrix. J Cell Physiol 151 (1992) 497-505
    • (1992) J Cell Physiol , vol.151 , pp. 497-505
    • Mooney, D.J.1    Hansen, L.2    Vacanti, J.P.3    Langer, R.4    Farmer, S.5    Ingber, D.6
  • 40
    • 36049045365 scopus 로고    scopus 로고
    • Synthetic sandwich culture of 3D hepatocyte monolayer
    • Du Y., Han R., Wen F., San S.N.S., Xia L., Wohland T., et al. Synthetic sandwich culture of 3D hepatocyte monolayer. Biomaterials 29 (2008) 290-301
    • (2008) Biomaterials , vol.29 , pp. 290-301
    • Du, Y.1    Han, R.2    Wen, F.3    San, S.N.S.4    Xia, L.5    Wohland, T.6
  • 41
    • 0042904900 scopus 로고    scopus 로고
    • Comparison of primary human hepatocytes and hepatoma cell line HEPG2 with regard to their biotransformation properties
    • Wilkening S., Stahl F., and Bader A. Comparison of primary human hepatocytes and hepatoma cell line HEPG2 with regard to their biotransformation properties. Drug Metab Dispos 31 (2003) 1035-1042
    • (2003) Drug Metab Dispos , vol.31 , pp. 1035-1042
    • Wilkening, S.1    Stahl, F.2    Bader, A.3
  • 42
    • 0030916822 scopus 로고    scopus 로고
    • Use of hepatocyte cultures for study of hepatotoxic compounds
    • Guillozo A., Morel F., Langouet S., Maheo K., and Rissel M. Use of hepatocyte cultures for study of hepatotoxic compounds. J Hepatol 26 Suppl. 2 (1997) 23-80
    • (1997) J Hepatol , vol.26 , Issue.SUPPL. 2 , pp. 23-80
    • Guillozo, A.1    Morel, F.2    Langouet, S.3    Maheo, K.4    Rissel, M.5
  • 43
    • 0043092060 scopus 로고    scopus 로고
    • Human hepatocytes as a tool for studying toxicity and drug metabolism
    • Gomez-Lechon M.J., Donato M.T., Catsell J.V., and Jover R. Human hepatocytes as a tool for studying toxicity and drug metabolism. Curr Drug Met 4 (2003) 292-312
    • (2003) Curr Drug Met , vol.4 , pp. 292-312
    • Gomez-Lechon, M.J.1    Donato, M.T.2    Catsell, J.V.3    Jover, R.4
  • 44
    • 0030443087 scopus 로고    scopus 로고
    • Development of a hybrid liver support system: a review
    • Gerlach J.C. Development of a hybrid liver support system: a review. Int J Artif Organs 19 (1996) 645-654
    • (1996) Int J Artif Organs , vol.19 , pp. 645-654
    • Gerlach, J.C.1
  • 45
    • 45249089679 scopus 로고    scopus 로고
    • A new culture technique for hepatocyte organoid formation and long-term maintenance of liver specific functions
    • Mizumoto H., Ishihara K., Nakazawa K., Ijima H., Funatsu K., and Kajiwara T. A new culture technique for hepatocyte organoid formation and long-term maintenance of liver specific functions. Tissue Eng Part C 14 (2008) 167-175
    • (2008) Tissue Eng Part C , vol.14 , pp. 167-175
    • Mizumoto, H.1    Ishihara, K.2    Nakazawa, K.3    Ijima, H.4    Funatsu, K.5    Kajiwara, T.6
  • 46
    • 0036022004 scopus 로고    scopus 로고
    • Cultivation of primary porcine hepatocytes in an OXY-HFB for use as a bioartificial liver device
    • Jasmund I., Langsch A., Simmoteit R., and Bader A. Cultivation of primary porcine hepatocytes in an OXY-HFB for use as a bioartificial liver device. Biotechnol Prog 18 (2002) 839-846
    • (2002) Biotechnol Prog , vol.18 , pp. 839-846
    • Jasmund, I.1    Langsch, A.2    Simmoteit, R.3    Bader, A.4
  • 47
    • 0029974085 scopus 로고    scopus 로고
    • Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily
    • Ono S., Hatanaka T., Miyazawa S., Tsutsui M., Aoyama T., Gonzales F.J., et al. Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily. Xenobiotica 26 (1996) 1155-1166
    • (1996) Xenobiotica , vol.26 , pp. 1155-1166
    • Ono, S.1    Hatanaka, T.2    Miyazawa, S.3    Tsutsui, M.4    Aoyama, T.5    Gonzales, F.J.6
  • 48
    • 0030763543 scopus 로고    scopus 로고
    • Drug metabolism in hepatocyte sandwich cultures of rats and humans
    • Kern A., Bader A., Pichlmayr R., and Sewing K.-F. Drug metabolism in hepatocyte sandwich cultures of rats and humans. Biochem Pharmacol 54 (1997) 761-772
    • (1997) Biochem Pharmacol , vol.54 , pp. 761-772
    • Kern, A.1    Bader, A.2    Pichlmayr, R.3    Sewing, K.-F.4
  • 49
    • 3343026223 scopus 로고    scopus 로고
    • UDP-glucuronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucuronidation by human liver
    • Court M.H., Hao Q., Krishnaswamy S., Bekaii-Saab T., Al-Rohaimi A., von Moltke L.L., et al. UDP-glucuronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucuronidation by human liver. J Pharmacol Exp Ther 310 2 (2004) 656-665
    • (2004) J Pharmacol Exp Ther , vol.310 , Issue.2 , pp. 656-665
    • Court, M.H.1    Hao, Q.2    Krishnaswamy, S.3    Bekaii-Saab, T.4    Al-Rohaimi, A.5    von Moltke, L.L.6


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