Influence of Flow Conditions and Matrix Coatings on Growth and Differentiation of Three-Dimensionally Cultured Rat Hepatocytes

Tissue Engineering

Volumn 10, Issue 1-2, 2004, Pages 165-174

  Fiegel, Henning C ^a   Havers, Joerg ^a   Kneser, Ulrich ^b   Smith, Molly K ^c   Moeller, Tim ^a   Kluth, Dietrich ^a   Mooney, David J ^c   Rogiers, Xavier ^a   Kaufmann, Peter M ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 4; FIBRONECTIN; LAMININ; POLYGLACTIN;

ANIMAL CELL; ARTICLE; BIOREACTOR; CELL CULTURE; CELL FUNCTION; CELL GROWTH; CELL SURFACE; CELL VIABILITY; CELL WALL; CHEMICAL MODIFICATION; CONTROLLED STUDY; CULTURE MEDIUM; EXTRACELLULAR MATRIX; LIVER CELL; LIVER CELL CULTURE; LIVER FUNCTION; NONHUMAN; PRIORITY JOURNAL; RAT; THREE DIMENSIONAL IMAGING; TIME SERIES ANALYSIS;

ANIMALS; CELL CULTURE TECHNIQUES; COATED MATERIALS, BIOCOMPATIBLE; EXTRACELLULAR MATRIX; HEPATOCYTES; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; POLYGLYCOLIC ACID; POLYMERS; RATS; RATS, INBRED LEW;

EID: 1042277975     PISSN: 10763279     EISSN: None     Source Type: Journal    
DOI: 10.1089/107632704322791817     Document Type: Article

References (26)

1. Keeffe, E.B. Liver transplantation: Current status and novel approaches to liver replacement. Gastroenterology 120, 749, 2001.
2. Malhi, H., and Gupta, S. Hepatocyte transplantation: New horizons and challenges. J. Hepatobiliary Pancreat. Surg. 8, 40, 2001.
3. Strain, A.J., and Neuberger, J.M. A bioartificial liver: State of the art. Science 295, 1005, 2002.
4. Guha, C., Roy-Chowdhury, N., Jaregui, H., and Roy-Chowdhury, J. Hepatocyte based gene therapies. J. Hepatobiliary Pancreat. Surg. 8, 51, 2001.
5. Borel Rinkes, I.H., Toner, M., Sheeha, S.J., Tompkins, R.G., and Yarmush, M.L. Long-term functional recovery of hepatocytes after cryopreservation in a three dimensional culture configuration. Cell Transplant. 1, 281, 1992.
6. Kaufmann, P.M., Sano, K., Uyama, S., Takeda, T., and Vacanti, J.P. Heterotopic hepatocyte transplantation: Assessing the impact of hepatotrophic stimulation. Transplant. Proc. 26, 2240, 1994.
7. Mooney, D., Hansen, L., Vacanti, J., Langer, R., Framer, S., and Ingber, D. Switching from differentiation to growth in hepatocytes: Control by extracellular matrix. J. Cell. Physiol. 151, 497, 1992.
8. Berthiaume, F., Moghe, P.V., Toner, M., and Yarmush, M.L. Effect of extracellular matrix topology on cell structure, function, and physiological responsiveness: Hepatocytes cultured in a sandwich configuration. FASEB J. 10, 1471, 1996.
9. Block, G.D., Locker, J., Bowen, W.C., Petersen, B.E., Katyal, S., Strom, S.C., Riley, T., Howard, T.A., and Michalopoulos, G.K. Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF, and TGF α in a chemically defined (HGM) medium. J. Cell Biol. 132, 1133, 1995.
10. Reid, L.M. Stem cell biology, hormone/matrix synergies and liver differentiation. Curr. Opin. Cell Biol. 2, 121, 1990.
11. Guguen-Guillouzo, C., Clement, B., Baffet, G., Beaumont, C., Morel-Chany, E., Claise, D., and Guillouzo, A. Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type. Exp. Cell Res. 143, 47, 1983.
12. Shimaoka, S., Nakamura, T., and Ichihara, A. Stimulation of growth of primary cultured adult rat hepatocytes without growth factors by coculture with nonparenchymal liver cells. Exp. Cell Res. 172, 228, 1987.
13. Bathia, S.N., Balis, U.J., Yarmush, M.L., and Toner, M. Effect of cell-cell interactions in preservation of cellular phenotype: Cocultivation of hepatocytes and non-parenchymal cells. FASEB J. 13, 1883, 1999.
14. Kaufmann, P.M., Fiegel, H.C., Kneser, U., Pollok, J.M., Kluth, D., and Rogiers, X. Influence of pancreatic islets on growth and differentiation of hepatocytes in co-culture. Tissue Eng. 5, 583, 1999.
15. Mizuguchi, T., Hui, T., Palm, K., Sugiyama, N., Mitaka, T., Demetriou, A.A., and Rozga, J. Enhanced proliferation and differentiation of rat hepatocytes cultured with bone marrow stromal cells. J. Cell. Physiol. 189, 106, 2001.
16. Rozga, J., Williams, F., Ro, M.S., Neuzil, D.F., Giorgio, T.D., Backfisch, G., Moscioni, A.D., Hakim, R., and Demetriou, A.A., Development of a bioartificial liver: Properties and function of a hollow-fiber module inoculated with liver cells. Hepatology 17, 258, 1993.
17. Kaufmann, P.M., Heimrath, S., Kim, B.S., and Mooney, D.J. Highly porous polymer matrices as a three-dimensional culture system for hepatocytes. Cell Transplant. 6, 463, 1997.
18. Torok, E., Pollok, J.M., Ma, P.X., Vogel, C., Dandri, M., Petersen, J., Burda, M.R., Kaufmann, P.M., Kluth, D., and Rogiers, X. Hepatic tissue engineering on 3-dimensional biodegradable polymers within a pulsatile flow bioreactor. Dig. Dis. Surg. 18, 196, 2001.
19. Seglen, P.O. Preparation of rat liver cells. Methods Cell Biol. 13, 29, 1976.
20. Schwerer, B., Bach, M., and Bernsteiner, H. ELISA for determination of albumin in the nanogram range: Assay in cerebrospinal fluid and comparison with radial immunodiffusion. Clin. Chim. Acta 163, 237, 1987.
21. Roy, P., Washizu, J., Tilles, A.W., Yarmush, M.L., and Toner, M. Effect of flow on the detoxification function of rat hepatocytes in a bioartificial liver reactor. Cell Transplant. 10, 609, 2001.
22. Park, T.G. Perfusion culture of hepatocytes within galactose-derivatized biodegradable poly-lactide-co-glycolic scaffolds prepared by gas foaming of effervescent salts. J. Biomed. Mater. Res. 59, 127, 2002.
23. Ben-Ze'ev, A.G., Robinson, A.G., Bucher, S., and Farmer, S.R. Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes. Proc. Natl. Acad. Sci. U.S.A. 85, 1, 1988.
24. Bissell, D.M., Arenson, D.M., Maher, J.J., and Roll, F.J. Support of cultured hepatocytes by laminin-rich gel. Am. Soc, Clin. Invest. 79, 801, 1987.
25. Ingber, D.E., Folkman, J. How does extracellular matrix control capillary morphogenesis? Cell 58, 803, 1989.
26. Hasirci, V., Berthiaume, F., Bondre, S.P., Gresser, J.D., Tarantolo, D.J., Toner, M., and Wise, D.L. Expression of liver-specific functions by rat hepatocytes seeded in treated poly-lactide-co-glycolic acid biodegradable foams. Tissue Eng. 7, 385, 2001.