-
1
-
-
22144432283
-
A systematic review of the prevalence of schizophrenia
-
Saha, S., Chant, D., Welham, J., McGrath, J. A systematic review of the prevalence of schizophrenia. PLoS Med 2005, 2(5): e141.
-
(2005)
PLoS Med
, vol.2
, Issue.5
-
-
Saha, S.1
Chant, D.2
Welham, J.3
McGrath, J.4
-
2
-
-
12344327212
-
Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
-
Harrison, P.J., Weinberger, D.R. Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence. Mol Psychiatry 2005, 10(1): 40-68.
-
(2005)
Mol Psychiatry
, vol.10
, Issue.1
, pp. 40-68
-
-
Harrison, P.J.1
Weinberger, D.R.2
-
3
-
-
0029918481
-
What are the functional consequences of neurocognitive deficits in schizophrenia?
-
Green, M.F. What are the functional consequences of neurocognitive deficits in schizophrenia? Am J Psychiatry 1996, 153(3): 321-30.
-
(1996)
Am J Psychiatry
, vol.153
, Issue.3
, pp. 321-330
-
-
Green, M.F.1
-
4
-
-
7544244277
-
Longitudinal studies of cognition and functional outcome in schizophrenia: Implications for MATRICS
-
Green, M.F., Kern, R.S., Heaton, R.K. Longitudinal studies of cognition and functional outcome in schizophrenia: Implications for MATRICS. Schizophr Res 2004, 72(1): 41-51.
-
(2004)
Schizophr Res
, vol.72
, Issue.1
, pp. 41-51
-
-
Green, M.F.1
Kern, R.S.2
Heaton, R.K.3
-
5
-
-
33645230162
-
Negative symptoms and cognitive deficits: What is the nature of their relationship?
-
Harvey, P.D., Koren, D., Reichenberg, A., Bowie, C.R. Negative symptoms and cognitive deficits: What is the nature of their relationship? Schizophr Bull 2006, 32(2): 250-8.
-
(2006)
Schizophr Bull
, vol.32
, Issue.2
, pp. 250-258
-
-
Harvey, P.D.1
Koren, D.2
Reichenberg, A.3
Bowie, C.R.4
-
6
-
-
51749091526
-
Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT(6) receptor antagonist: Comparison among antipsychotics
-
Rodefer, J.S., Nguyen, T.N., Karlsson, J.J., Arnt, J. Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT(6) receptor antagonist: Comparison among antipsychotics. Neuropsychopharmacology 2008, 33(11): 2657-66.
-
(2008)
Neuropsychopharmacology
, vol.33
, Issue.11
, pp. 2657-2666
-
-
Rodefer, J.S.1
Nguyen, T.N.2
Karlsson, J.J.3
Arnt, J.4
-
7
-
-
38049057135
-
Efficacy of antipsychotics to reverse phencyclidine-induced social interaction deficits in female rats - A preliminary investigation
-
Snigdha, S., Neill, J.C. Efficacy of antipsychotics to reverse phencyclidine-induced social interaction deficits in female rats - A preliminary investigation. Behav Brain Res 2008, 187(2): 489-94.
-
(2008)
Behav Brain Res
, vol.187
, Issue.2
, pp. 489-494
-
-
Snigdha, S.1
Neill, J.C.2
-
8
-
-
33645056175
-
The effect of atypical and classical antipsychotics on sub-chronic PCP-induced cognitive deficits in a reversal-learning paradigm
-
Abdul-Monim, Z., Reynolds, G.P., Neill, J.C. The effect of atypical and classical antipsychotics on sub-chronic PCP-induced cognitive deficits in a reversal-learning paradigm. Behav Brain Res 2006, 169(2): 263-73.
-
(2006)
Behav Brain Res
, vol.169
, Issue.2
, pp. 263-273
-
-
Abdul-Monim, Z.1
Reynolds, G.P.2
Neill, J.C.3
-
9
-
-
33847125372
-
Sub-chronic psychotomimetic phencyclidine induces deficits in reversal learning and alterations in parvalbumin-immunoreactive expression in the rat
-
Abdul-Monim, Z., Neill, J.C., Reynolds, G.P. Sub-chronic psychotomimetic phencyclidine induces deficits in reversal learning and alterations in parvalbumin-immunoreactive expression in the rat. J Psychopharmacol 2007, 21(2): 198-205.
-
(2007)
J Psychopharmacol
, vol.21
, Issue.2
, pp. 198-205
-
-
Abdul-Monim, Z.1
Neill, J.C.2
Reynolds, G.P.3
-
10
-
-
34548621479
-
Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat
-
Grayson, B., Idris, N.F., Neill, J.C. Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat. Behav Brain Res 2007, 184(1): 31-8.
-
(2007)
Behav Brain Res
, vol.184
, Issue.1
, pp. 31-38
-
-
Grayson, B.1
Idris, N.F.2
Neill, J.C.3
-
11
-
-
59449101712
-
Comparison of haloperidol, risperidone, sertindole and modafinil to reverse an attentional set-shifting impairment following sub-chronic PCP administration in the rat - A back translational study
-
Berl
-
Goetghebeur, P., Dias, R. Comparison of haloperidol, risperidone, sertindole and modafinil to reverse an attentional set-shifting impairment following sub-chronic PCP administration in the rat - A back translational study. Psychopharmacology (Berl) 2008.
-
(2008)
Psychopharmacology
-
-
Goetghebeur, P.1
Dias, R.2
-
12
-
-
33646818313
-
Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia
-
Horacek, J., Bubenikova-Valesova, V., Kopecek, M. et al. Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia. CNS Drugs 2006, 20(5): 389-409.
-
(2006)
CNS Drugs
, vol.20
, Issue.5
, pp. 389-409
-
-
Horacek, J.1
Bubenikova-Valesova, V.2
Kopecek, M.3
-
13
-
-
41649108196
-
Emerging opportunities for antipsychotic drug discovery in the postgenomic era
-
Marino, M.J., Knutsen, L.J., Williams, M. Emerging opportunities for antipsychotic drug discovery in the postgenomic era. J Med Chem 2008, 51(5): 1077-107.
-
(2008)
J Med Chem
, vol.51
, Issue.5
, pp. 1077-1107
-
-
Marino, M.J.1
Knutsen, L.J.2
Williams, M.3
-
14
-
-
33644671816
-
Opinion: NK3 receptor antagonists: The next generation of antipsychotics?
-
Spooren, W., Riemer, C., Meltzer, H. Opinion: NK3 receptor antagonists: The next generation of antipsychotics? Nat Rev Drug Discov 2005, 4(12): 967-75.
-
(2005)
Nat Rev Drug Discov
, vol.4
, Issue.12
, pp. 967-975
-
-
Spooren, W.1
Riemer, C.2
Meltzer, H.3
-
15
-
-
34948858402
-
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized phase 2 clinical trial
-
Patil, S.T., Zhang, L., Martenyi, F.V. et al. Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized phase 2 clinical trial. Nat Med 2007, 13(9): 1102-7.
-
(2007)
Nat Med
, vol.13
, Issue.9
, pp. 1102-1107
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.V.3
-
16
-
-
0029930927
-
Risperidone compared with new and reference antipsychotic drugs: In vitro and in vivo receptor binding
-
Schotte, A., Janssen, P.F., Gommeren, W. et al. Risperidone compared with new and reference antipsychotic drugs: In vitro and in vivo receptor binding. Psychopharmacology (Berl) 1996, 124(1-2): 57-73.
-
(1996)
Psychopharmacology (Berl)
, vol.124
, Issue.1-2
, pp. 57-73
-
-
Schotte, A.1
Janssen, P.F.2
Gommeren, W.3
-
17
-
-
0032007608
-
Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence
-
Arnt, J., Skarsfeldt, T. Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence. Neuropsychopharmacology 1998, 18(2): 63-101.
-
(1998)
Neuropsychopharmacology
, vol.18
, Issue.2
, pp. 63-101
-
-
Arnt, J.1
Skarsfeldt, T.2
-
18
-
-
4644271084
-
Magic shotguns versus magic bullets: Selectively non-selective drugs for mood disorders and schizophrenia
-
Roth, B.L., Sheffler, D.J., Kroeze, W.K. Magic shotguns versus magic bullets: Selectively non-selective drugs for mood disorders and schizophrenia. Nat Rev Drug Discov 2004, 3(4): 353-9.
-
(2004)
Nat Rev Drug Discov
, vol.3
, Issue.4
, pp. 353-359
-
-
Roth, B.L.1
Sheffler, D.J.2
Kroeze, W.K.3
-
19
-
-
38049040370
-
Multi- and single-target agents for major psychiatric diseases: Therapeutic opportunities and challenges
-
Wong, E.H., Nikam, S.S., Shahid, M. Multi- and single-target agents for major psychiatric diseases: Therapeutic opportunities and challenges. Curr Opin Investig Drugs 2008, 9(1): 28-36.
-
(2008)
Curr Opin Investig Drugs
, vol.9
, Issue.1
, pp. 28-36
-
-
Wong, E.H.1
Nikam, S.S.2
Shahid, M.3
-
20
-
-
47249104675
-
The evolution of drug development in schizophrenia: Past issues and future opportunities
-
Carpenter, W.T., Koenig, J.I. The evolution of drug development in schizophrenia: Past issues and future opportunities. Neuropsychopharmacology 2008, 33(9): 2061-79.
-
(2008)
Neuropsychopharmacology
, vol.33
, Issue.9
, pp. 2061-2079
-
-
Carpenter, W.T.1
Koenig, J.I.2
-
21
-
-
0347091932
-
Glutamate, dopamine, and schizophrenia: From pathophysiology to treatment
-
Laruelle, M., Kegeles, L.S., Abi-Dargham, A. Glutamate, dopamine, and schizophrenia: From pathophysiology to treatment. Ann N Y Acad Sci 2003, 1003: 138-58.
-
(2003)
Ann N Y Acad Sci
, vol.1003
, pp. 138-158
-
-
Laruelle, M.1
Kegeles, L.S.2
Abi-Dargham, A.3
-
22
-
-
0031799667
-
Increased striatal dopamine transmission in schizophrenia: Confirmation in a second cohort
-
Abi-Dargham, A., Gil, R., Krystal, J. et al. Increased striatal dopamine transmission in schizophrenia: Confirmation in a second cohort. Am J Psychiatry 1998, 155(6): 761-7.
-
(1998)
Am J Psychiatry
, vol.155
, Issue.6
, pp. 761-767
-
-
Abi-Dargham, A.1
Gil, R.2
Krystal, J.3
-
23
-
-
0035810850
-
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia
-
Egan, M.F., Goldberg, T.E., Kolachana, B.S. et al. Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci USA 2001, 98(12): 6917-22.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.12
, pp. 6917-6922
-
-
Egan, M.F.1
Goldberg, T.E.2
Kolachana, B.S.3
-
24
-
-
0023987236
-
Dextro-amphetamine diminishes negative symptoms in schizophrenia
-
van Kammen, D.P., Boronow, J.J. Dextro-amphetamine diminishes negative symptoms in schizophrenia. Int Clin Psychopharmacol 1988, 3(2): 111-21.
-
(1988)
Int Clin Psychopharmacol
, vol.3
, Issue.2
, pp. 111-121
-
-
van Kammen, D.P.1
Boronow, J.J.2
-
25
-
-
0026025322
-
Cognitive and behavioral effects of the coadministration of dextroamphetamine and haloperidol in schizophrenia
-
Goldberg, T.E., Bigelow, L.B., Weinberger, D.R., Daniel, D.G., Kleinman, J.E. Cognitive and behavioral effects of the coadministration of dextroamphetamine and haloperidol in schizophrenia. Am J Psychiatry 1991, 148(1): 78-84.
-
(1991)
Am J Psychiatry
, vol.148
, Issue.1
, pp. 78-84
-
-
Goldberg, T.E.1
Bigelow, L.B.2
Weinberger, D.R.3
Daniel, D.G.4
Kleinman, J.E.5
-
26
-
-
0025948748
-
The effect of amphetamine on regional cerebral blood flow during cognitive activation in schizophrenia
-
Daniel, D.G., Weinberger, D.R., Jones, D.W. et al. The effect of amphetamine on regional cerebral blood flow during cognitive activation in schizophrenia. J Neurosci 1991, 11(7): 1907-17.
-
(1991)
J Neurosci
, vol.11
, Issue.7
, pp. 1907-1917
-
-
Daniel, D.G.1
Weinberger, D.R.2
Jones, D.W.3
-
27
-
-
0030851961
-
Subchronic phencyclidine administration reduces mesoprefrontal dopamine utilization and impairs prefrontal cortical-dependent cognition in the rat
-
Jentsch, J.D., Tran, A., Le, D., Youngren, K.D., Roth, R.H. Subchronic phencyclidine administration reduces mesoprefrontal dopamine utilization and impairs prefrontal cortical-dependent cognition in the rat. Neunopsychopharmacology 1997, 17(2): 92-9.
-
(1997)
Neunopsychopharmacology
, vol.17
, Issue.2
, pp. 92-99
-
-
Jentsch, J.D.1
Tran, A.2
Le, D.3
Youngren, K.D.4
Roth, R.H.5
-
28
-
-
0032575715
-
Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats
-
Moghaddam, B., Adams, B.W. Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science 1998, 281(5381): 1349-52.
-
(1998)
Science
, vol.281
, Issue.5381
, pp. 1349-1352
-
-
Moghaddam, B.1
Adams, B.W.2
-
29
-
-
0033764334
-
Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited
-
Callicott, J.H., Bertolino, A., Mattay, V.S. et al. Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited. Cereb Cortex 2000, 10(11): 1078-92.
-
(2000)
Cereb Cortex
, vol.10
, Issue.11
, pp. 1078-1092
-
-
Callicott, J.H.1
Bertolino, A.2
Mattay, V.S.3
-
30
-
-
0037947438
-
Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine
-
Mattay, V.S., Goldberg, T.E., Fera, F. et al. Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. Proc Natl Acad Sci USA 2003, 100(10): 6186-91.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.10
, pp. 6186-6191
-
-
Mattay, V.S.1
Goldberg, T.E.2
Fera, F.3
-
31
-
-
0032030496
-
M100907, a selective 5-HT2A receptor antagonist and a potential antipsychotic drug, facilitates N-methyl-D-aspartate-receptor mediated neurotransmission in the rat medial prefrontal cortical neurons in vitro
-
Arvanov, V.L., Wang, R.Y. M100907, a selective 5-HT2A receptor antagonist and a potential antipsychotic drug, facilitates N-methyl-D-aspartate-receptor mediated neurotransmission in the rat medial prefrontal cortical neurons in vitro. Neuropsychopharmacology 1998, 18(3): 197-209.
-
(1998)
Neuropsychopharmacology
, vol.18
, Issue.3
, pp. 197-209
-
-
Arvanov, V.L.1
Wang, R.Y.2
-
32
-
-
1442306000
-
Potentiation of NMDA receptor currents by dopamine D1 receptors in prefrontal cortex
-
Chen, G., Greengard, P., Yan, Z. Potentiation of NMDA receptor currents by dopamine D1 receptors in prefrontal cortex. Proc Natl Acad Sci USA 2004, 101(8): 2596-600.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.8
, pp. 2596-2600
-
-
Chen, G.1
Greengard, P.2
Yan, Z.3
-
33
-
-
22344444314
-
Combined alpha2 and D2/3 receptor blockade enhances cortical glutamatergic transmission and reverses cognitive impairment in the rat
-
Marcus, M.M., Jardemark, K.E., Wadenberg, M.L., Langlois, X., Hertel, P., Svensson, T.H. Combined alpha2 and D2/3 receptor blockade enhances cortical glutamatergic transmission and reverses cognitive impairment in the rat. Int J Neuropsychopharmacol 2005, 8(3): 315-27.
-
(2005)
Int J Neuropsychopharmacol
, vol.8
, Issue.3
, pp. 315-327
-
-
Marcus, M.M.1
Jardemark, K.E.2
Wadenberg, M.L.3
Langlois, X.4
Hertel, P.5
Svensson, T.H.6
-
34
-
-
34548797583
-
AC260584 (4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo [1,4]oxazin-3-one), a selective muscarinic M1 receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus
-
Li, Z., Bonhaus, D.W., Huang, M., Prus, A.J., Dai, J., Meltzer, H.Y. AC260584 (4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo [1,4]oxazin-3-one), a selective muscarinic M1 receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus. Eur J Pharmacol 2007, 572(2-3): 129-37.
-
(2007)
Eur J Pharmacol
, vol.572
, Issue.2-3
, pp. 129-137
-
-
Li, Z.1
Bonhaus, D.W.2
Huang, M.3
Prus, A.J.4
Dai, J.5
Meltzer, H.Y.6
-
35
-
-
10744223983
-
N-Desmethyl-clozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl-D-aspartate receptor activity
-
Sur, C., Mallorga, P.J., Wittmann, M. et al. N-Desmethyl-clozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl-D-aspartate receptor activity. Proc Natl Acad Sci USA 2003, 100(23): 13674-9.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.23
, pp. 13674-13679
-
-
Sur, C.1
Mallorga, P.J.2
Wittmann, M.3
-
36
-
-
3142701270
-
Targeting the dopamine D1 receptor in schizophrenia: Insights for cognitive dysfunction
-
Goldman-Rakic, P.S., Castner, S.A., Svensson, T.H., Siever, L.J., Williams, G.V. Targeting the dopamine D1 receptor in schizophrenia: Insights for cognitive dysfunction. Psychopharmacology (Berl) 2004, 174(1): 3-16.
-
(2004)
Psychopharmacology (Berl)
, vol.174
, Issue.1
, pp. 3-16
-
-
Goldman-Rakic, P.S.1
Castner, S.A.2
Svensson, T.H.3
Siever, L.J.4
Williams, G.V.5
-
37
-
-
34347336444
-
Neuropharmacological profile of bifeprunox: Merits and limitations in comparison with other third-generation antipsychotics
-
Newman-Tancredi, A., Cussac, D., Depoortere, R. Neuropharmacological profile of bifeprunox: Merits and limitations in comparison with other third-generation antipsychotics. Curr Opin Investig Drugs 2007, 8(7): 539-54.
-
(2007)
Curr Opin Investig Drugs
, vol.8
, Issue.7
, pp. 539-554
-
-
Newman-Tancredi, A.1
Cussac, D.2
Depoortere, R.3
-
38
-
-
0025055214
-
Dopamine D-2 agonists with high and low efficacies: Differentiation by behavioural techniques
-
Arnt, J., Hyttel, J. Dopamine D-2 agonists with high and low efficacies: Differentiation by behavioural techniques. J Neural Transm Gen Sect 1990, 80(1): 33-50.
-
(1990)
J Neural Transm Gen Sect
, vol.80
, Issue.1
, pp. 33-50
-
-
Arnt, J.1
Hyttel, J.2
-
39
-
-
33947583891
-
The Akt-GSK-3 signaling cascade in the actions of dopamine
-
Beaulieu, J.M., Gainetdinov, R.R., Caron, M.G. The Akt-GSK-3 signaling cascade in the actions of dopamine. Trends Pharmacol Sci 2007, 28(4): 166-72.
-
(2007)
Trends Pharmacol Sci
, vol.28
, Issue.4
, pp. 166-172
-
-
Beaulieu, J.M.1
Gainetdinov, R.R.2
Caron, M.G.3
-
40
-
-
33845718611
-
Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways
-
Urban, J.D., Vargas, G.A., von Zastrow, M., Mailman, R.B. Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways. Neuropsychopharmacology 2007, 32(1): 67-77.
-
(2007)
Neuropsychopharmacology
, vol.32
, Issue.1
, pp. 67-77
-
-
Urban, J.D.1
Vargas, G.A.2
von Zastrow, M.3
Mailman, R.B.4
-
41
-
-
34748864737
-
The pipeline and future of drug development in schizophrenia
-
Gray, J.A., Roth, B.L. The pipeline and future of drug development in schizophrenia. Mol Psychiatry 2007, 12(10): 904-22.
-
(2007)
Mol Psychiatry
, vol.12
, Issue.10
, pp. 904-922
-
-
Gray, J.A.1
Roth, B.L.2
-
42
-
-
43049146626
-
Asenapine: A novel psychopharmacologic agent with a unique human receptor signature
-
Shahid, M., Walker, G.B., Zorn, S.H., Wong, E.H. Asenapine: A novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol 2008.
-
(2008)
J Psychopharmacol
-
-
Shahid, M.1
Walker, G.B.2
Zorn, S.H.3
Wong, E.H.4
-
43
-
-
25144456112
-
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
-
Lieberman, J.A., Stroup, T.S., McEvoy, J.P. et al. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med 2005, 353(12): 1209-23.
-
(2005)
N Engl J Med
, vol.353
, Issue.12
, pp. 1209-1223
-
-
Lieberman, J.A.1
Stroup, T.S.2
McEvoy, J.P.3
-
44
-
-
27744452434
-
Preclinical pharmacology of FMPD [6-fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2- methyl-4H-3-thia-4,9-diazabenzo[f]azulene]: A potential novel antipsychotic with lower histamine H1 receptor affinity than olanzapine
-
Rasmussen, K., Benvenga, M.J., Bymaster, F.P. et al. Preclinical pharmacology of FMPD [6-fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2- methyl-4H-3-thia-4,9-diazabenzo[f]azulene]: A potential novel antipsychotic with lower histamine H1 receptor affinity than olanzapine. J Pharmacol Exp Ther 2005, 315(3): 1265-77.
-
(2005)
J Pharmacol Exp Ther
, vol.315
, Issue.3
, pp. 1265-1277
-
-
Rasmussen, K.1
Benvenga, M.J.2
Bymaster, F.P.3
-
45
-
-
30344464352
-
7-Phenylsulfonyl-tetrahydro-3-benzazepine derivatives as antipsychotic agents
-
Howard, H.R. 7-Phenylsulfonyl-tetrahydro-3-benzazepine derivatives as antipsychotic agents. Expert Opin Ther Pat 2005, 15(12): 1811-5.
-
(2005)
Expert Opin Ther Pat
, vol.15
, Issue.12
, pp. 1811-1815
-
-
Howard, H.R.1
-
46
-
-
33846087420
-
Studies towards the identification of a new generation of atypical antipsychotic agents
-
Garzya, V., Forbes, I.T., Gribble, A.D. et al. Studies towards the identification of a new generation of atypical antipsychotic agents. Bioorg Med Chem Lett 2007, 17(2): 400-5.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, Issue.2
, pp. 400-405
-
-
Garzya, V.1
Forbes, I.T.2
Gribble, A.D.3
-
47
-
-
42449099422
-
Preclinical characterization of selective PDE10A inhibitors: A new therapeutic approach to the treatment of schizophrenia
-
Schmidt, C.J., Chapin, D.S., Cianfrogna, J. et al. Preclinical characterization of selective PDE10A inhibitors: A new therapeutic approach to the treatment of schizophrenia. J Pharmacol Exp Ther 2008, 325(2): 681-90.
-
(2008)
J Pharmacol Exp Ther
, vol.325
, Issue.2
, pp. 681-690
-
-
Schmidt, C.J.1
Chapin, D.S.2
Cianfrogna, J.3
-
48
-
-
33947302705
-
Phosphodiesterase 10A inhibitors: A novel approach to the treatment of the symptoms of schizophrenia
-
Menniti, F.S., Chappie, T.A., Humphrey, J.M., Schmidt, C.J. Phosphodiesterase 10A inhibitors: A novel approach to the treatment of the symptoms of schizophrenia. Curr Opin Investig Drugs 2007, 8(1): 54-9.
-
(2007)
Curr Opin Investig Drugs
, vol.8
, Issue.1
, pp. 54-59
-
-
Menniti, F.S.1
Chappie, T.A.2
Humphrey, J.M.3
Schmidt, C.J.4
-
49
-
-
16244376475
-
PDE10A inhibition reverses subchronic PCP-induced deficits in attentional set-shifting in rats
-
Rodefer, J.S., Murphy, E.R., Baxter, M.G. PDE10A inhibition reverses subchronic PCP-induced deficits in attentional set-shifting in rats. Eur J Neurosci 2005, 21(4): 1070-6.
-
(2005)
Eur J Neurosci
, vol.21
, Issue.4
, pp. 1070-1076
-
-
Rodefer, J.S.1
Murphy, E.R.2
Baxter, M.G.3
-
50
-
-
33847022578
-
The potential therapeutic use of phosphodiesterase 10 inhibitors
-
Kehler, J., Ritzén, A., Greve, D.R. The potential therapeutic use of phosphodiesterase 10 inhibitors. Expert Opin Ther Pat 2007, 17(2): 147-58.
-
(2007)
Expert Opin Ther Pat
, vol.17
, Issue.2
, pp. 147-158
-
-
Kehler, J.1
Ritzén, A.2
Greve, D.R.3
-
51
-
-
60749137312
-
Recommended INN: List 54
-
Farampator. Recommended INN: List 54. WHO Drug Information 2005, 19(3). http://www.who.int/druginformation/vol19num3_2005/R-List54.pdf
-
(2005)
WHO Drug Information
, vol.19
, Issue.3
-
-
Farampator1
-
52
-
-
33746288751
-
Positive modulation of glutamatergic receptors potentiates the suppressive effects of antipsychotics on conditioned avoidance responding in rats
-
Olsen, C.K., Kreilgaard, M., Didriksen, M. Positive modulation of glutamatergic receptors potentiates the suppressive effects of antipsychotics on conditioned avoidance responding in rats. Pharmacol Biochem Behav 2006, 84(2): 259-65.
-
(2006)
Pharmacol Biochem Behav
, vol.84
, Issue.2
, pp. 259-265
-
-
Olsen, C.K.1
Kreilgaard, M.2
Didriksen, M.3
-
53
-
-
34249079802
-
Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers
-
Wezenberg, E., Verkes, R.J., Ruigt, G.S., Hulstijn, W., Sabbe, B.G. Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers. Neuropsychopharmacology 2007, 32(6): 1272-83.
-
(2007)
Neuropsychopharmacology
, vol.32
, Issue.6
, pp. 1272-1283
-
-
Wezenberg, E.1
Verkes, R.J.2
Ruigt, G.S.3
Hulstijn, W.4
Sabbe, B.G.5
-
54
-
-
34249083509
-
Pharmacology of ampakine modulators: From AMPA receptors to synapses and behavior
-
Arai, A.C., Kessler, M. Pharmacology of ampakine modulators: From AMPA receptors to synapses and behavior. Curr Drug Targets 2007, 8(5): 583-602.
-
(2007)
Curr Drug Targets
, vol.8
, Issue.5
, pp. 583-602
-
-
Arai, A.C.1
Kessler, M.2
-
55
-
-
60749088478
-
Recommended INN: List 57
-
Vabicaserin. Recommended INN: List 57. WHO Drug Information 2007, 21(1). http://www.who.int/druginformation/vol21num1_2007/R-List57.pdf
-
(2007)
WHO Drug Information
, vol.21
, Issue.1
-
-
Vabicaserin1
-
56
-
-
34250162538
-
In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders
-
Rorick-Kehn, L.M., Johnson, B.G., Knitowski, K.M. et al. In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders. Psychopharmacology (Berl) 2007, 193(1): 121-36.
-
(2007)
Psychopharmacology (Berl)
, vol.193
, Issue.1
, pp. 121-136
-
-
Rorick-Kehn, L.M.1
Johnson, B.G.2
Knitowski, K.M.3
-
57
-
-
0033019791
-
Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens
-
Kuroki, T., Meltzer, H.Y., Ichikawa, J. Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens. J Pharmacol Exp Ther 1999, 288(2): 774-81.
-
(1999)
J Pharmacol Exp Ther
, vol.288
, Issue.2
, pp. 774-781
-
-
Kuroki, T.1
Meltzer, H.Y.2
Ichikawa, J.3
-
58
-
-
0037195552
-
Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: Role of 5-HT1A receptor agonism
-
Ichikawa, J., Li, Z., Dai, J., Meltzer, H.Y. Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: Role of 5-HT1A receptor agonism. Brain Res 2002, 956(2): 349-57.
-
(2002)
Brain Res
, vol.956
, Issue.2
, pp. 349-357
-
-
Ichikawa, J.1
Li, Z.2
Dai, J.3
Meltzer, H.Y.4
-
59
-
-
0036176263
-
Atypical, but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum
-
Ichikawa, J., Dai, J., O'Laughlin, I.A., Fowler, W.L., Meltzer, H.Y. Atypical, but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum. Neuropsychopharmacology 2002, 26(3): 325-39.
-
(2002)
Neuropsychopharmacology
, vol.26
, Issue.3
, pp. 325-339
-
-
Ichikawa, J.1
Dai, J.2
O'Laughlin, I.A.3
Fowler, W.L.4
Meltzer, H.Y.5
-
60
-
-
0030848168
-
Schizophrenia and L-745,870, a novel dopamine D4 receptor antagonist
-
Bristow, L.J., Kramer, M.S., Kulagowski, J., Patel, S., Ragan, C.I., Seabrook, G.R. Schizophrenia and L-745,870, a novel dopamine D4 receptor antagonist. Trends Pharmacol Sci 1997, 18(6): 186-8.
-
(1997)
Trends Pharmacol Sci
, vol.18
, Issue.6
, pp. 186-188
-
-
Bristow, L.J.1
Kramer, M.S.2
Kulagowski, J.3
Patel, S.4
Ragan, C.I.5
Seabrook, G.R.6
-
61
-
-
12644311276
-
Pharmacological characterization of U-101387, a dopamine D4 receptor selective antagonist
-
Merchant, K.M., Gill, G.S., Harris, D.W. et al. Pharmacological characterization of U-101387, a dopamine D4 receptor selective antagonist. J Pharmacol Exp Ther 1996, 279(3): 1392-403.
-
(1996)
J Pharmacol Exp Ther
, vol.279
, Issue.3
, pp. 1392-1403
-
-
Merchant, K.M.1
Gill, G.S.2
Harris, D.W.3
-
62
-
-
1542617757
-
Effectiveness of the selective D4 antagonist sonepiprazole in schizophrenia: A placebo-controlled trial
-
Corrigan, M.H., Gallen, C.C., Bonura, M.L., Merchant, K.M. Effectiveness of the selective D4 antagonist sonepiprazole in schizophrenia: A placebo-controlled trial. Biol Psychiatry 2004, 55(5): 445-51.
-
(2004)
Biol Psychiatry
, vol.55
, Issue.5
, pp. 445-451
-
-
Corrigan, M.H.1
Gallen, C.C.2
Bonura, M.L.3
Merchant, K.M.4
-
63
-
-
0033824142
-
The selective dopamine D4 receptor antagonist, PNU-101387G, prevents stress-induced cognitive deficits in monkeys
-
Arnsten, A.F., Murphy, B., Merchant, K. The selective dopamine D4 receptor antagonist, PNU-101387G, prevents stress-induced cognitive deficits in monkeys. Neuropsychopharmacology 2000, 23(4): 405-10.
-
(2000)
Neuropsychopharmacology
, vol.23
, Issue.4
, pp. 405-410
-
-
Arnsten, A.F.1
Murphy, B.2
Merchant, K.3
-
64
-
-
0032587235
-
Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys
-
Jentsch, J.D., Taylor, J.R., Redmond, D.E. Jr., Elsworth, J.D., Youngren, K.D., Roth, R.H. Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys. Psychopharmacology (Berl) 1999, 142(1): 78-84.
-
(1999)
Psychopharmacology (Berl)
, vol.142
, Issue.1
, pp. 78-84
-
-
Jentsch, J.D.1
Taylor, J.R.2
Redmond Jr., D.E.3
Elsworth, J.D.4
Youngren, K.D.5
Roth, R.H.6
-
65
-
-
0031159043
-
The effects of a selective D4 dopamine receptor antagonist (L-745,870) in acutely psychotic inpatients with schizophrenia. D4 Dopamine Antagonist Group
-
Kramer, M.S., Last, B., Getson, A., Reines, S.A. The effects of a selective D4 dopamine receptor antagonist (L-745,870) in acutely psychotic inpatients with schizophrenia. D4 Dopamine Antagonist Group. Arch Gen Psychiatry 1997, 54(6): 567-72.
-
(1997)
Arch Gen Psychiatry
, vol.54
, Issue.6
, pp. 567-572
-
-
Kramer, M.S.1
Last, B.2
Getson, A.3
Reines, S.A.4
-
66
-
-
30944469609
-
Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting
-
Floresco, S.B., Magyar, O., Ghods-Sharifi, S., Vexelman, C., Tse, M.T. Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting. Neuropsychopharmacology 2006, 31(2): 297-309.
-
(2006)
Neuropsychopharmacology
, vol.31
, Issue.2
, pp. 297-309
-
-
Floresco, S.B.1
Magyar, O.2
Ghods-Sharifi, S.3
Vexelman, C.4
Tse, M.T.5
-
67
-
-
34648847361
-
Lu 35-138 ((+)-(S)-3-{1-[2-(1-acetyl-2,3-dihydro-1H- indol-3-yl)ethyl]-3,6-dihydro-2H-pyridin-4-yl}-6-chloro-1H-indole), a dopamine D4 receptor antagonist and serotonin reuptake inhibitor: Characterisation of its in vitro profile and pre-clinical antipsychotic potential
-
Hertel, P., Didriksen, M., Pouzet, B. et al. Lu 35-138 ((+)-(S)-3-{1-[2-(1-acetyl-2,3-dihydro-1H- indol-3-yl)ethyl]-3,6-dihydro-2H-pyridin-4-yl}-6-chloro-1H-indole), a dopamine D4 receptor antagonist and serotonin reuptake inhibitor: Characterisation of its in vitro profile and pre-clinical antipsychotic potential. Eur J Pharmacol 2007, 573(1-3): 148-60.
-
(2007)
Eur J Pharmacol
, vol.573
, Issue.1-3
, pp. 148-160
-
-
Hertel, P.1
Didriksen, M.2
Pouzet, B.3
-
68
-
-
38749136624
-
S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b- tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent: I. Receptor-binding profile and functional actions at G-protein-coupled receptors
-
Millan, M.J., Mannoury la Cour, C., Novi, F. et al. S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b- tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent: I. Receptor-binding profile and functional actions at G-protein-coupled receptors. J Pharmacol Exp Ther 2008, 324(2): 587-99.
-
(2008)
J Pharmacol Exp Ther
, vol.324
, Issue.2
, pp. 587-599
-
-
Millan, M.J.1
Mannoury la Cour, C.2
Novi, F.3
-
69
-
-
40849116470
-
S33138 (N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1] benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenyl-acetamide), a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. III. Actions in models of therapeutic activity and induction of side effects
-
Millan, M.J., Loiseau, F., Dekeyne, A. et al. S33138 (N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1] benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenyl-acetamide), a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. III. Actions in models of therapeutic activity and induction of side effects. J Pharmacol Exp Ther 2008, 324(3): 1212-26.
-
(2008)
J Pharmacol Exp Ther
, vol.324
, Issue.3
, pp. 1212-1226
-
-
Millan, M.J.1
Loiseau, F.2
Dekeyne, A.3
-
70
-
-
0031553742
-
The dopamine D3 receptor antagonist, (+)-S 14297, blocks the cataleptic properties of haloperidol in rats
-
Millan, M.J., Gressier, H., Brocco, M. The dopamine D3 receptor antagonist, (+)-S 14297, blocks the cataleptic properties of haloperidol in rats. Eur J Pharmacol 1997, 321(3): R7-9.
-
(1997)
Eur J Pharmacol
, vol.321
, Issue.3
-
-
Millan, M.J.1
Gressier, H.2
Brocco, M.3
-
71
-
-
38749091288
-
-
Millan, M.J., Svenningsson, P., Ashby, C.R. Jr. et al. S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]- benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiological and behavioral characterization in vivo. J Pharmacol Exp Ther 2008, 324(2): 600-11.
-
Millan, M.J., Svenningsson, P., Ashby, C.R. Jr. et al. S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]- benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiological and behavioral characterization in vivo. J Pharmacol Exp Ther 2008, 324(2): 600-11.
-
-
-
-
72
-
-
20444378913
-
The role of central dopamine D3 receptors in drug addiction: A review of pharmacological evidence
-
Heidbreder, C.A., Gardner, E.L., Xi, Z.X. et al. The role of central dopamine D3 receptors in drug addiction: A review of pharmacological evidence. Brain Res Brain Res Rev 2005, 49(1): 77-105.
-
(2005)
Brain Res Brain Res Rev
, vol.49
, Issue.1
, pp. 77-105
-
-
Heidbreder, C.A.1
Gardner, E.L.2
Xi, Z.X.3
-
73
-
-
33847071676
-
Selective antagonism at dopamine D3 receptors attenuates cocaine-seeking behaviour in the rat
-
Cervo, L., Cocco, A., Petrella, C., Heidbreder, C.A. Selective antagonism at dopamine D3 receptors attenuates cocaine-seeking behaviour in the rat. Int J Neuropsychopharmacol 2007, 10(2): 167-81.
-
(2007)
Int J Neuropsychopharmacol
, vol.10
, Issue.2
, pp. 167-181
-
-
Cervo, L.1
Cocco, A.2
Petrella, C.3
Heidbreder, C.A.4
-
74
-
-
6344231535
-
Dihydrexidine - The first full dopamine D1 receptor agonist
-
Salmi, P., Isacson, R., Kull, B. Dihydrexidine - The first full dopamine D1 receptor agonist. CNS Drug Rev 2004, 10(3): 230-42.
-
(2004)
CNS Drug Rev
, vol.10
, Issue.3
, pp. 230-242
-
-
Salmi, P.1
Isacson, R.2
Kull, B.3
-
75
-
-
34447252651
-
A single 20 mg dose of the full D1 dopamine agonist dihydrexidine (DAR-0100) increases prefrontal perfusion in schizophrenia
-
Mu, Q., Johnson, K., Morgan, P.S. et al. A single 20 mg dose of the full D1 dopamine agonist dihydrexidine (DAR-0100) increases prefrontal perfusion in schizophrenia. Schizophr Res 2007, 94(1-3): 332-41.
-
(2007)
Schizophr Res
, vol.94
, Issue.1-3
, pp. 332-341
-
-
Mu, Q.1
Johnson, K.2
Morgan, P.S.3
-
76
-
-
0032868798
-
The role of serotonin in antipsychotic drug action
-
Meltzer, H.Y. The role of serotonin in antipsychotic drug action. Neuropsychopharmacology 1999, 21(2, Suppl.): 106S-15S.
-
(1999)
Neuropsychopharmacology
, vol.21
, Issue.2 and SUPPL.
-
-
Meltzer, H.Y.1
-
77
-
-
2942538034
-
Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder
-
Meltzer, H.Y., Arvanitis, L., Bauer, D., Rein, W. Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder. Am J Psychiatry 2004, 161(6): 975-84.
-
(2004)
Am J Psychiatry
, vol.161
, Issue.6
, pp. 975-984
-
-
Meltzer, H.Y.1
Arvanitis, L.2
Bauer, D.3
Rein, W.4
-
78
-
-
0033624308
-
High 5-HT2A receptor occupancy in M100907-treated schizophrenic patients
-
Talvik-Lotfi, M., Nyberg, S., Nordstrom, A.L. et al. High 5-HT2A receptor occupancy in M100907-treated schizophrenic patients. Psychopharmacology (Berl) 2000, 148(4): 400-3.
-
(2000)
Psychopharmacology (Berl)
, vol.148
, Issue.4
, pp. 400-403
-
-
Talvik-Lotfi, M.1
Nyberg, S.2
Nordstrom, A.L.3
-
79
-
-
0035022182
-
Antagonism at 5-HT(2A) receptors potentiates the effect of haloperidol in a conditioned avoidance response task in rats
-
Wadenberg, M.G., Browning, J.L., Young, K.A., Hicks, P.B. Antagonism at 5-HT(2A) receptors potentiates the effect of haloperidol in a conditioned avoidance response task in rats. Pharmacol Biochem Behav 2001, 68(3): 363-70.
-
(2001)
Pharmacol Biochem Behav
, vol.68
, Issue.3
, pp. 363-370
-
-
Wadenberg, M.G.1
Browning, J.L.2
Young, K.A.3
Hicks, P.B.4
-
80
-
-
27744577804
-
ACP-103, a 5-HT2A/2C inverse agonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens
-
Li, Z., Ichikawa, J., Huang, M., Prus, A.J., Dai, J., Meltzer, H.Y. ACP-103, a 5-HT2A/2C inverse agonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Psychopharmacology (Berl) 2005, 183(2): 144-53.
-
(2005)
Psychopharmacology (Berl)
, vol.183
, Issue.2
, pp. 144-153
-
-
Li, Z.1
Ichikawa, J.2
Huang, M.3
Prus, A.J.4
Dai, J.5
Meltzer, H.Y.6
-
82
-
-
33747329318
-
Pharmacological approaches to the management of cognitive dysfunction in schizophrenia
-
Harvey, P.D., McClure, M.M. Pharmacological approaches to the management of cognitive dysfunction in schizophrenia. Drugs 2006, 66(11): 1465-73.
-
(2006)
Drugs
, vol.66
, Issue.11
, pp. 1465-1473
-
-
Harvey, P.D.1
McClure, M.M.2
-
83
-
-
34547218379
-
Effects of olanzapine, quetiapine, and risperidone on neurocognitive function in early psychosis: A randomized, double-blind 52-week comparison
-
Keefe, R.S., Sweeney, J.A., Gu, H. et al. Effects of olanzapine, quetiapine, and risperidone on neurocognitive function in early psychosis: A randomized, double-blind 52-week comparison. Am J Psychiatry 2007, 164(7): 1061-71.
-
(2007)
Am J Psychiatry
, vol.164
, Issue.7
, pp. 1061-1071
-
-
Keefe, R.S.1
Sweeney, J.A.2
Gu, H.3
-
84
-
-
34247643916
-
Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial
-
Keefe, R.S., Bilder, R.M., Davis, S.M. et al. Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial. Arch Gen Psychiatry 2007, 64(6): 633-47.
-
(2007)
Arch Gen Psychiatry
, vol.64
, Issue.6
, pp. 633-647
-
-
Keefe, R.S.1
Bilder, R.M.2
Davis, S.M.3
-
85
-
-
60749109416
-
6 antagonists improve a subchronic phencyclidine-induced reversal learning deficit in rats
-
June 21-25, Venice
-
6 antagonists improve a subchronic phencyclidine-induced reversal learning deficit in rats. 1st SIRSC Conf (June 21-25, Venice) 2008.
-
(2008)
1st SIRSC Conf
-
-
Neill, J.C.1
Idris, N.F.2
Arnt, J.3
-
86
-
-
60749097906
-
Sertindole improves a sub-chronic PCP-induced deficit in object recognition memory in the rat; comparison with risperidone
-
June 21-25, Venice
-
Neill, J.C., Grayson, B., Idris, N.F., Witten, L.M., Brennum, L.T., Arnt, J. Sertindole improves a sub-chronic PCP-induced deficit in object recognition memory in the rat; comparison with risperidone. 1st SIRSC Conf (June 21-25, Venice) 2008.
-
(2008)
1st SIRSC Conf
-
-
Neill, J.C.1
Grayson, B.2
Idris, N.F.3
Witten, L.M.4
Brennum, L.T.5
Arnt, J.6
-
87
-
-
40849097398
-
A preliminary investigation into the effects of antipsychotics on subchronic phencyclidine-induced deficits in attentional set-shifting in female rats
-
McLean, S.L., Beck, J.P., Woolley, M.L., Neill, J.C. A preliminary investigation into the effects of antipsychotics on subchronic phencyclidine-induced deficits in attentional set-shifting in female rats. Behav Brain Res 2008, 189 (1): 152-8.
-
(2008)
Behav Brain Res
, vol.189
, Issue.1
, pp. 152-158
-
-
McLean, S.L.1
Beck, J.P.2
Woolley, M.L.3
Neill, J.C.4
-
88
-
-
0026032408
-
Antipsychotic-like profile of combined treatment with raclopride and 8-OH-DPAT in the rat: Enhancement of antipsychotic-like effects without catalepsy
-
Wadenberg, M.L., Ahlenius, S. Antipsychotic-like profile of combined treatment with raclopride and 8-OH-DPAT in the rat: Enhancement of antipsychotic-like effects without catalepsy. J Neural Transm Gen Sect 1991, 83(1-2): 43-53.
-
(1991)
J Neural Transm Gen Sect
, vol.83
, Issue.1-2
, pp. 43-53
-
-
Wadenberg, M.L.1
Ahlenius, S.2
-
89
-
-
0032732960
-
R(+)-8-OH-DPAT, a serotonin(1A) receptor agonist, potentiated S(-)-sulpiride-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens but not striatum
-
Ichikawa, J., Meltzer, H.Y. R(+)-8-OH-DPAT, a serotonin(1A) receptor agonist, potentiated S(-)-sulpiride-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens but not striatum. J Pharmacol Exp Ther 1999I, 291(3): 1227-32.
-
(1999)
J Pharmacol Exp Ther
, vol.291
, Issue.3
, pp. 1227-1232
-
-
Ichikawa, J.1
Meltzer, H.Y.2
-
90
-
-
0034810016
-
Enhancement of cognitive performance in schizophrenia by addition of tandospirone to neuroleptic treatment
-
Sumiyoshi, T., Matsui, M., Nohara, S. et al. Enhancement of cognitive performance in schizophrenia by addition of tandospirone to neuroleptic treatment. Am J Psychiatry 2001, 158(10): 1722-5.
-
(2001)
Am J Psychiatry
, vol.158
, Issue.10
, pp. 1722-1725
-
-
Sumiyoshi, T.1
Matsui, M.2
Nohara, S.3
-
91
-
-
0025942009
-
-
Ishizumi, K., Kojima, A., Antoku, F. Synthesis and anxiolytic activity of N-substituted cyclic imides (1R*,2S*,3R*,4S*)-N-[4-[4-(2-pyrimidinyl)-1- piperazinyl]butyl]-2,3-bicyclo-[2.2.1]heptanedicarboximide (tandospirone) and related compounds. Chem Pharm Bull (Tokyo) 1991, 39(9): 2288-300.
-
Ishizumi, K., Kojima, A., Antoku, F. Synthesis and anxiolytic activity of N-substituted cyclic imides (1R*,2S*,3R*,4S*)-N-[4-[4-(2-pyrimidinyl)-1- piperazinyl]butyl]-2,3-bicyclo-[2.2.1]heptanedicarboximide (tandospirone) and related compounds. Chem Pharm Bull (Tokyo) 1991, 39(9): 2288-300.
-
-
-
-
93
-
-
0032588764
-
SB 242084, a selective serotonin2C receptor antagonist, increases dopaminergic transmission in the mesolimbic system
-
Di Matteo, V., Di Giovanni, G., Di Mascio, M., Esposito, E. SB 242084, a selective serotonin2C receptor antagonist, increases dopaminergic transmission in the mesolimbic system. Neuropharmacology 1999, 38(8): 1195-205.
-
(1999)
Neuropharmacology
, vol.38
, Issue.8
, pp. 1195-1205
-
-
Di Matteo, V.1
Di Giovanni, G.2
Di Mascio, M.3
Esposito, E.4
-
94
-
-
41649109395
-
5-HT2C receptor agonists as an innovative approach for psychiatric disorders
-
Rosenzweig-Lipson, S., Dunlop, J., Marquis, K.L. 5-HT2C receptor agonists as an innovative approach for psychiatric disorders. Drug News Perspect 2007, 20(9): 565-71.
-
(2007)
Drug News Perspect
, vol.20
, Issue.9
, pp. 565-571
-
-
Rosenzweig-Lipson, S.1
Dunlop, J.2
Marquis, K.L.3
-
95
-
-
37249034101
-
Atypical antipsychotic-induced metabolic side effects: Insights from receptor-binding profiles
-
Nasrallah, H.A. Atypical antipsychotic-induced metabolic side effects: Insights from receptor-binding profiles. Mol Psychiatry 2008, 13(1): 27-35.
-
(2008)
Mol Psychiatry
, vol.13
, Issue.1
, pp. 27-35
-
-
Nasrallah, H.A.1
-
96
-
-
33845995465
-
Pharmacological profile of the 5-HT(2C) receptor agonist WAY-163909; therapeutic potential in multiple indications
-
Dunlop, J., Marquis, K.L., Lim, H.K. et al. Pharmacological profile of the 5-HT(2C) receptor agonist WAY-163909; therapeutic potential in multiple indications. CNS Drug Rev 2006, 12(3-4): 167-77.
-
(2006)
CNS Drug Rev
, vol.12
, Issue.3-4
, pp. 167-177
-
-
Dunlop, J.1
Marquis, K.L.2
Lim, H.K.3
-
97
-
-
33846348402
-
5-HT6 receptor antagonist SB-399885 potentiates haloperidol and risperidone-induced dopamine efflux in the medial prefrontal cortex or hippocampus
-
Li, Z., Huang, M., Prus, A.J., Dai, J., Meltzer, H.Y. 5-HT6 receptor antagonist SB-399885 potentiates haloperidol and risperidone-induced dopamine efflux in the medial prefrontal cortex or hippocampus. Brain Res 2007, 1134(1): 70-8.
-
(2007)
Brain Res
, vol.1134
, Issue.1
, pp. 70-78
-
-
Li, Z.1
Huang, M.2
Prus, A.J.3
Dai, J.4
Meltzer, H.Y.5
-
98
-
-
0346250850
-
5-HT6 receptor antagonist SB-271046 enhances extracellular levels of monoamines in the rat medial prefrontal cortex
-
Lacroix, L.P., Dawson, L.A., Hagan, J.J., Heidbreder, C.A. 5-HT6 receptor antagonist SB-271046 enhances extracellular levels of monoamines in the rat medial prefrontal cortex. Synapse 2004, 51(2): 158-64.
-
(2004)
Synapse
, vol.51
, Issue.2
, pp. 158-164
-
-
Lacroix, L.P.1
Dawson, L.A.2
Hagan, J.J.3
Heidbreder, C.A.4
-
99
-
-
0034782825
-
The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus
-
Dawson, L.A., Nguyen, H.Q., Li, P. The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus. Neuropsychopharmacology 2001, 25(5): 662-8.
-
(2001)
Neuropsychopharmacology
, vol.25
, Issue.5
, pp. 662-668
-
-
Dawson, L.A.1
Nguyen, H.Q.2
Li, P.3
-
100
-
-
33751162382
-
SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models
-
Hirst, W.D., Stean, T.O., Rogers, D.C. et al. SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models. Eur J Pharmacol 2006, 553(1-3): 109-19.
-
(2006)
Eur J Pharmacol
, vol.553
, Issue.1-3
, pp. 109-119
-
-
Hirst, W.D.1
Stean, T.O.2
Rogers, D.C.3
-
101
-
-
28044437798
-
5-HT6 receptors: A novel target for cognitive enhancement
-
Mitchell, E.S., Neumaier, J.F. 5-HT6 receptors: A novel target for cognitive enhancement. Pharmacol Ther 2005, 108(3): 320-33.
-
(2005)
Pharmacol Ther
, vol.108
, Issue.3
, pp. 320-333
-
-
Mitchell, E.S.1
Neumaier, J.F.2
-
102
-
-
34347369304
-
Reversal of PCP-induced learning and memory deficits in the Morris' water maze by sertindole and other antipsychotics
-
Didriksen, M., Skarsfeldt, T., Arnt, J. Reversal of PCP-induced learning and memory deficits in the Morris' water maze by sertindole and other antipsychotics. Psychopharmacology (Berl) 2007, 193(2): 225-33.
-
(2007)
Psychopharmacology (Berl)
, vol.193
, Issue.2
, pp. 225-233
-
-
Didriksen, M.1
Skarsfeldt, T.2
Arnt, J.3
-
103
-
-
0001962034
-
Receptor profiles of antipsychotics
-
Ellenbroek, B.A, Cools, A.R, Eds, Birkhäuser Verlag, Basel
-
Leysen, J.E. Receptor profiles of antipsychotics. In: Atypical Antipsychotics. Ellenbroek, B.A., Cools, A.R. (Eds.). Birkhäuser Verlag, Basel, 2000, 57-81.
-
(2000)
Atypical Antipsychotics
, pp. 57-81
-
-
Leysen, J.E.1
-
104
-
-
36849008793
-
Course of recovety of cognitive impairment in patients with schizophrenia: A randomised double-blind study comparing sertindole and haloperidol
-
Gallhofer, B., Jaanson, P., Mittoux, A., Tanghoj, P., Lis, S., Krieger, S. Course of recovety of cognitive impairment in patients with schizophrenia: A randomised double-blind study comparing sertindole and haloperidol. Pharmacopsychiatry 2007, 40(6): 275-86.
-
(2007)
Pharmacopsychiatry
, vol.40
, Issue.6
, pp. 275-286
-
-
Gallhofer, B.1
Jaanson, P.2
Mittoux, A.3
Tanghoj, P.4
Lis, S.5
Krieger, S.6
-
105
-
-
0036119234
-
Effects of the 5-HT(6) receptor antagonist, SB-271046, in animal models for schizophrenia
-
Pouzet, B., Didriksen, M., Arnt, J. Effects of the 5-HT(6) receptor antagonist, SB-271046, in animal models for schizophrenia. Pharmacol Biochem Behav 2002, 71(4): 635-43.
-
(2002)
Pharmacol Biochem Behav
, vol.71
, Issue.4
, pp. 635-643
-
-
Pouzet, B.1
Didriksen, M.2
Arnt, J.3
-
106
-
-
0036850564
-
Noradrenaline reuptake inhibition enhances the antipsychotic-like effect of raclopride and potentiates D2-blockage-induced dopamine release in the medial prefrontal cortex of the rat
-
Linner, L., Wiker, C., Wadenberg, M.L., Schalling, M., Svensson, T.H. Noradrenaline reuptake inhibition enhances the antipsychotic-like effect of raclopride and potentiates D2-blockage-induced dopamine release in the medial prefrontal cortex of the rat. Neuropsychopharmacology 2002, 27(5): 691-8.
-
(2002)
Neuropsychopharmacology
, vol.27
, Issue.5
, pp. 691-698
-
-
Linner, L.1
Wiker, C.2
Wadenberg, M.L.3
Schalling, M.4
Svensson, T.H.5
-
107
-
-
33748659877
-
Serotonin reuptake inhibitors: The corner stone in treatment of depression for half a century - A medicinal chemistry survey
-
Moltzen, E.K., Bang-Andersen, B. Serotonin reuptake inhibitors: The corner stone in treatment of depression for half a century - A medicinal chemistry survey. Curr Top Med Chem 2006, 6(17): 1801-23.
-
(2006)
Curr Top Med Chem
, vol.6
, Issue.17
, pp. 1801-1823
-
-
Moltzen, E.K.1
Bang-Andersen, B.2
-
108
-
-
49549104014
-
N-Desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT(1A) agonist, as a putative mediator of quetiapine's antidepressant activity
-
Jensen, N.H., Rodriguiz, R.M., Caron, M.G., Wetsel, W.C., Rothman, R.B., Roth, B.L. N-Desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT(1A) agonist, as a putative mediator of quetiapine's antidepressant activity. Neuropsychopharmacology 2008, 33(10): 2303-12.
-
(2008)
Neuropsychopharmacology
, vol.33
, Issue.10
, pp. 2303-2312
-
-
Jensen, N.H.1
Rodriguiz, R.M.2
Caron, M.G.3
Wetsel, W.C.4
Rothman, R.B.5
Roth, B.L.6
-
109
-
-
0022654413
-
Idazoxan: A novel pharmacological tool for the study of alpha 2-adrenoceptors
-
Dabire, H. Idazoxan: A novel pharmacological tool for the study of alpha 2-adrenoceptors. J Pharmacol 1986, 17(2): 113-8.
-
(1986)
J Pharmacol
, vol.17
, Issue.2
, pp. 113-118
-
-
Dabire, H.1
-
110
-
-
0007673447
-
Enhanced cortical dopamine output and antipsychotic-like effects of raclopride by alpha2 adrenoceptor blockade
-
Hertel, P., Fagerquist, M.V., Svensson, T.H. Enhanced cortical dopamine output and antipsychotic-like effects of raclopride by alpha2 adrenoceptor blockade. Science 1999, 286(5437): 105-7.
-
(1999)
Science
, vol.286
, Issue.5437
, pp. 105-107
-
-
Hertel, P.1
Fagerquist, M.V.2
Svensson, T.H.3
-
111
-
-
0029949349
-
Idazoxan and response to typical neuroleptics in treatment-resistant schizophrenia. Comparison with the atypical neuroleptic, clozapine
-
Litman, R.E., Su, T.P., Potter, W.Z., Hong, W.W., Pickar, D. Idazoxan and response to typical neuroleptics in treatment-resistant schizophrenia. Comparison with the atypical neuroleptic, clozapine. Br J Psychiatry 1996, 168(5): 571-9.
-
(1996)
Br J Psychiatry
, vol.168
, Issue.5
, pp. 571-579
-
-
Litman, R.E.1
Su, T.P.2
Potter, W.Z.3
Hong, W.W.4
Pickar, D.5
-
112
-
-
0033777513
-
Enhancement of antipsychotic-like effects by combined treatment with the alpha1-adrenoceptor antagonist prazosin and the dopamine D2 receptor antagonist raclopride in rats
-
Wadenberg, M.L., Hertel, P., Fernholm, R., Hygge, B.K., Ahlenius, S., Svensson, T.H. Enhancement of antipsychotic-like effects by combined treatment with the alpha1-adrenoceptor antagonist prazosin and the dopamine D2 receptor antagonist raclopride in rats. J Neural Transm 2000, 107(10): 1229-38.
-
(2000)
J Neural Transm
, vol.107
, Issue.10
, pp. 1229-1238
-
-
Wadenberg, M.L.1
Hertel, P.2
Fernholm, R.3
Hygge, B.K.4
Ahlenius, S.5
Svensson, T.H.6
-
113
-
-
0030816278
-
The relationship of pharmacology to side effects
-
Casey, D.E. The relationship of pharmacology to side effects. J Clin Psychiatry 1997, 58(Suppl. 10): 55-62.
-
(1997)
J Clin Psychiatry
, vol.58
, Issue.SUPPL. 10
, pp. 55-62
-
-
Casey, D.E.1
-
114
-
-
58149174516
-
TBPB is a highly selective M1 allosteric muscarinic receptor agonist in vitro and produces robust antipsychotic-like effects in vivo
-
Jones, C.K., Brady, A.E., Bubser, M. et al. TBPB is a highly selective M1 allosteric muscarinic receptor agonist in vitro and produces robust antipsychotic-like effects in vivo. Neuropsychopharmacology 2006, 31(Suppl. 1): S116-7.
-
(2006)
Neuropsychopharmacology
, vol.31
, Issue.SUPPL. 1
-
-
Jones, C.K.1
Brady, A.E.2
Bubser, M.3
-
115
-
-
37249054670
-
An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission
-
Shirey, J.K., Xiang, Z., Orton, D. et al. An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission. Nat Chem Biol 2008, 4(1): 42-50.
-
(2008)
Nat Chem Biol
, vol.4
, Issue.1
, pp. 42-50
-
-
Shirey, J.K.1
Xiang, Z.2
Orton, D.3
-
116
-
-
42249095496
-
Schizophrenia: Moving beyond monoamine antagonists
-
Conn, P.J., Tamminga, C., Schoepp, D.D., Lindsley, C. Schizophrenia: Moving beyond monoamine antagonists. Mol Interv 2008, 8(2): 99-107.
-
(2008)
Mol Interv
, vol.8
, Issue.2
, pp. 99-107
-
-
Conn, P.J.1
Tamminga, C.2
Schoepp, D.D.3
Lindsley, C.4
-
117
-
-
0037604627
-
Muscarinic receptors as a target for drugs treating schizophrenia
-
Bymaster, F.P., Felder, C., Ahmed, S., McKinzie, D. Muscarinic receptors as a target for drugs treating schizophrenia. Curr Drug Targets CNS Neurol Disord 2002, 1(2): 163-81.
-
(2002)
Curr Drug Targets CNS Neurol Disord
, vol.1
, Issue.2
, pp. 163-181
-
-
Bymaster, F.P.1
Felder, C.2
Ahmed, S.3
McKinzie, D.4
-
118
-
-
34447257978
-
Pharmacology of N-desmethyl-clozapine
-
Lameh, J., Burstein, E.S., Taylor, E., Weiner, D.M., Vanover, K.E., Bonhaus, D.W. Pharmacology of N-desmethyl-clozapine. Pharmacol Ther 2007, 115(2): 223-31.
-
(2007)
Pharmacol Ther
, vol.115
, Issue.2
, pp. 223-231
-
-
Lameh, J.1
Burstein, E.S.2
Taylor, E.3
Weiner, D.M.4
Vanover, K.E.5
Bonhaus, D.W.6
-
119
-
-
34548679635
-
Neuronal nicotinic receptors: A perspective on two decades of drug discovery research
-
Arneric, S.P., Holladay, M., Williams, M. Neuronal nicotinic receptors: A perspective on two decades of drug discovery research. Biochem Pharmacol 2007, 74(8): 1092-101.
-
(2007)
Biochem Pharmacol
, vol.74
, Issue.8
, pp. 1092-1101
-
-
Arneric, S.P.1
Holladay, M.2
Williams, M.3
-
120
-
-
33745446987
-
Progress in acetylcholinesterase inhibitors for Alzheimer's disease
-
Bolognesi, M.L., Minarini, A., Tumiatti, V., Melchiorre, C. Progress in acetylcholinesterase inhibitors for Alzheimer's disease. Expert Opin Ther Pat 2006, 16(6): 811-23.
-
(2006)
Expert Opin Ther Pat
, vol.16
, Issue.6
, pp. 811-823
-
-
Bolognesi, M.L.1
Minarini, A.2
Tumiatti, V.3
Melchiorre, C.4
-
121
-
-
42049123448
-
Efficacy and safety of donepezil in patients with schizophrenia or schizoaffective disorder: Significant placebo/practice effects in a 12-week, randomized, double-blind, placebo-controlled trial
-
Keefe, R.S., Malhotra, A.K., Meltzer, H.Y. et al. Efficacy and safety of donepezil in patients with schizophrenia or schizoaffective disorder: Significant placebo/practice effects in a 12-week, randomized, double-blind, placebo-controlled trial. Neuropsychopharmacology 2007, 33(6): 1217-28.
-
(2007)
Neuropsychopharmacology
, vol.33
, Issue.6
, pp. 1217-1228
-
-
Keefe, R.S.1
Malhotra, A.K.2
Meltzer, H.Y.3
-
122
-
-
20144376337
-
Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-methylpyrrolidinyl]ethyl}-benzofuran-5-yl) benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties
-
Esbenshade, T.A., Fox, G.B., Krueger, K.M. et al. Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-methylpyrrolidinyl]ethyl}-benzofuran-5-yl) benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties. J Pharmacol Exp Ther 2005, 313(1): 165-75.
-
(2005)
J Pharmacol Exp Ther
, vol.313
, Issue.1
, pp. 165-175
-
-
Esbenshade, T.A.1
Fox, G.B.2
Krueger, K.M.3
-
123
-
-
34248562939
-
GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models
-
Medhurst, A.D., Atkins, A.R., Beresford, I.J. et al. GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models. J Pharmacol Exp Ther 2007, 321(3): 1032-45.
-
(2007)
J Pharmacol Exp Ther
, vol.321
, Issue.3
, pp. 1032-1045
-
-
Medhurst, A.D.1
Atkins, A.R.2
Beresford, I.J.3
-
124
-
-
21144439215
-
Selective H3 receptor (H3R) blockade: Broad efficacy in cognition and schizophrenia
-
Fox, G.B., Esbenshade, T.A., Pan, J.B. et al. Selective H3 receptor (H3R) blockade: Broad efficacy in cognition and schizophrenia. Inflamm Res 2005, 54(Suppl. 1): S23-4.
-
(2005)
Inflamm Res
, vol.54
, Issue.SUPPL. 1
-
-
Fox, G.B.1
Esbenshade, T.A.2
Pan, J.B.3
-
125
-
-
0037101814
-
Ciproxifan, a histamine H3-receptor antagonist/inverse agonist, potentiates neurochemical and behavioral effects of haloperidol in the rat
-
Pillot, C., Ortiz, J., Heron, A., Ridray, S., Schwartz, J.C., Arrang, J.M. Ciproxifan, a histamine H3-receptor antagonist/inverse agonist, potentiates neurochemical and behavioral effects of haloperidol in the rat. J Neurosci 2002, 22(16): 7272-80.
-
(2002)
J Neurosci
, vol.22
, Issue.16
, pp. 7272-7280
-
-
Pillot, C.1
Ortiz, J.2
Heron, A.3
Ridray, S.4
Schwartz, J.C.5
Arrang, J.M.6
-
126
-
-
36849005064
-
Glycine transport inhibitors and the treatment of schizophrenia
-
Javitt, D.C. Glycine transport inhibitors and the treatment of schizophrenia. Biol Psychiatry 2008, 63(1): 6-8.
-
(2008)
Biol Psychiatry
, vol.63
, Issue.1
, pp. 6-8
-
-
Javitt, D.C.1
-
127
-
-
33745026642
-
Inhibition of the glycine transporter GlyT-1 potentiates the effect of risperidone, but not clozapine, on glutamatergic transmission in the rat medial prefrontal cortex
-
Konradsson, A., Marcus, M.M., Hertel, P., Svensson, T.H., Jardemark, K.E. Inhibition of the glycine transporter GlyT-1 potentiates the effect of risperidone, but not clozapine, on glutamatergic transmission in the rat medial prefrontal cortex. Synapse 2006, 60(2): 102-8.
-
(2006)
Synapse
, vol.60
, Issue.2
, pp. 102-108
-
-
Konradsson, A.1
Marcus, M.M.2
Hertel, P.3
Svensson, T.H.4
Jardemark, K.E.5
-
128
-
-
29744453122
-
Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic
-
Depoortere, R., Dargazanli, G., Estenne-Bouhtou, G. et al. Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic. Neuropsychopharmacology 2005, 30(11): 1963-85.
-
(2005)
Neuropsychopharmacology
, vol.30
, Issue.11
, pp. 1963-1985
-
-
Depoortere, R.1
Dargazanli, G.2
Estenne-Bouhtou, G.3
-
129
-
-
60549114223
-
Glycine transporter 1 (GlyT1) inhibitors for the treatment of schizophrenia
-
Aug 17-21, Philadelphia, Abst MEDI 220
-
Wolkenberg, S.E. Glycine transporter 1 (GlyT1) inhibitors for the treatment of schizophrenia. 236th ACS Natl Meet (Aug 17-21, Philadelphia) 2008, Abst MEDI 220.
-
(2008)
236th ACS Natl Meet
-
-
Wolkenberg, S.E.1
-
130
-
-
20144381462
-
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models
-
Kinney, G.G., O'Brien, J.A., Lemaire, W. et al. A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models. J Pharmacol Exp Ther 2005, 313(1): 199-206.
-
(2005)
J Pharmacol Exp Ther
, vol.313
, Issue.1
, pp. 199-206
-
-
Kinney, G.G.1
O'Brien, J.A.2
Lemaire, W.3
-
131
-
-
34249888474
-
Stimulation of the metabotropic glutamate 2/3 receptor attenuates social novelty discrimination deficits induced by neonatal phencyclidine treatment
-
Harich, S., Gross, G., Bespalov, A. Stimulation of the metabotropic glutamate 2/3 receptor attenuates social novelty discrimination deficits induced by neonatal phencyclidine treatment. Psychopharmacology (Berl) 2007, 192(4): 511-9.
-
(2007)
Psychopharmacology (Berl)
, vol.192
, Issue.4
, pp. 511-519
-
-
Harich, S.1
Gross, G.2
Bespalov, A.3
-
132
-
-
36049021794
-
D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats
-
Karasawa, J., Hashimoto, K, Chaki, S. D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats. Behav Brain Res 2008, 186(1): 78-83.
-
(2008)
Behav Brain Res
, vol.186
, Issue.1
, pp. 78-83
-
-
Karasawa, J.1
Hashimoto, K.2
Chaki, S.3
-
133
-
-
2442695094
-
Spatial memory deficits induced by perinatal treatment of rats with PCP and reversal effect of D-serine
-
Andersen, J.D., Pouzet, B. Spatial memory deficits induced by perinatal treatment of rats with PCP and reversal effect of D-serine. Neuropsychopharmacology 2004, 29(6): 1080-90.
-
(2004)
Neuropsychopharmacology
, vol.29
, Issue.6
, pp. 1080-1090
-
-
Andersen, J.D.1
Pouzet, B.2
-
134
-
-
0344178117
-
Synergistic interactions between ampakines and antipsychotic drugs
-
Johnson, S.A., Luu, N.T., Herbst, T.A. et al. Synergistic interactions between ampakines and antipsychotic drugs. J Pharmacol Exp Ther 1999, 289(1): 392-7.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, Issue.1
, pp. 392-397
-
-
Johnson, S.A.1
Luu, N.T.2
Herbst, T.A.3
-
135
-
-
0041920952
-
The glycine transporter type 1 inhibitor N-[3-(4′-fluorophenyl)-3-(4′-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior
-
Kinney, G.G., Sur, C., Burno, M. et al. The glycine transporter type 1 inhibitor N-[3-(4′-fluorophenyl)-3-(4′-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior. J Neurosci 2003, 23(20): 7586-91.
-
(2003)
J Neurosci
, vol.23
, Issue.20
, pp. 7586-7591
-
-
Kinney, G.G.1
Sur, C.2
Burno, M.3
-
136
-
-
39149141396
-
Glutamate agonists for schizophrenia stimulate dopamine D2High receptors
-
Seeman, P. Glutamate agonists for schizophrenia stimulate dopamine D2High receptors. Schizophr Res 2008, 99(1-3): 373-4.
-
(2008)
Schizophr Res
, vol.99
, Issue.1-3
, pp. 373-374
-
-
Seeman, P.1
-
137
-
-
38549144692
-
Selective 5-HT6 receptor ligands: Progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders
-
Heal, D.J., Smith, S.L., Fisas, A., Codony, X., Buschmann, H. Selective 5-HT6 receptor ligands: Progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders. Pharmacol Ther 2008, 117(2):207-31.
-
(2008)
Pharmacol Ther
, vol.117
, Issue.2
, pp. 207-231
-
-
Heal, D.J.1
Smith, S.L.2
Fisas, A.3
Codony, X.4
Buschmann, H.5
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