5-HT6 Receptor Antagonist SB-271046 Enhances Extracellular Levels of Monoamines in the Rat Medial Prefrontal Cortex

Synapse

Volumn 51, Issue 2, 2004, Pages 158-164

  Lacroix, Laurent P ^a   Dawson, Lee A ^b   Hagan, Jim J ^b   Heidbreder, Christian A ^b  

^a GSK   (Italy)

^b NONE

Author keywords

5 HT6 receptor; Dopamine; Medial prefrontal cortex; Microdialysis; Norepinephrine; SB 271046; Serotonin

Indexed keywords

5 CHLORO N [4 METHOXY 3 (1 PIPERAZINYL)PHENYL] 3 METHYL 2 BENZOTHIOPHENESULFONAMIDE; BRAIN MONOAMINE; DOPAMINE; NORADRENALIN; SEROTONIN; SEROTONIN 6 ANTAGONIST; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG; BIOGENIC AMINE; SEROTONIN 6 RECEPTOR; SEROTONIN RECEPTOR; SULFONAMIDE; THIOPHENE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG EFFECT; EXTRACELLULAR SPACE; IN VIVO STUDY; MALE; MENTAL DISEASE; MICRODIALYSIS; NEUROTRANSMISSION; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; ANALYSIS OF VARIANCE; ANIMAL; BRAIN LEVEL; COMPARATIVE STUDY; DOSE RESPONSE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; METHODOLOGY; SPRAGUE DAWLEY RAT; TIME;

ANALYSIS OF VARIANCE; ANIMALS; BIOGENIC MONOAMINES; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SPACE; MALE; MICRODIALYSIS; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; SULFONAMIDES; THIOPHENES; TIME FACTORS;

EID: 0346250850     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.10288     Document Type: Article

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