-
1
-
-
0037449586
-
What are the tight targets for psychopharmacology?
-
Hyman, S.E. and Fenton, W.S. What are the tight targets for psychopharmacology? Science 299, 350-351 (2003).
-
(2003)
Science
, vol.299
, pp. 350-351
-
-
Hyman, S.E.1
Fenton, W.S.2
-
2
-
-
0029918481
-
What are the functional consequences of neurocognitive deficits in schizophrenia?
-
Green, M.F. What are the functional consequences of neurocognitive deficits in schizophrenia? Am. J. Psychiatry 153, 321-330 (1996).
-
(1996)
Am. J. Psychiatry
, vol.153
, pp. 321-330
-
-
Green, M.F.1
-
3
-
-
7544234237
-
Identification of separable cognitive factors in schizophrenia
-
Nuechterlein, K.H., Barch, D.M., Gold, J.M., Goldberg, T.E., Green, M.F., and Heaton, R.K. Identification of separable cognitive factors in schizophrenia. Schizophr. Res. 72, 29-39 (2004).
-
(2004)
Schizophr. Res
, vol.72
, pp. 29-39
-
-
Nuechterlein, K.H.1
Barch, D.M.2
Gold, J.M.3
Goldberg, T.E.4
Green, M.F.5
Heaton, R.K.6
-
4
-
-
3142680754
-
MATRICS: Measurement and Treatment Research to Improve Cognition in Schizophrenia
-
Geyer, M.A. and Tamminga, C. MATRICS: Measurement and Treatment Research to Improve Cognition in Schizophrenia. Psychopharmacology 174, 1-162 (2004).
-
(2004)
Psychopharmacology
, vol.174
, pp. 1-162
-
-
Geyer, M.A.1
Tamminga, C.2
-
5
-
-
20844439028
-
A summary of the FDA-NIMH-MATRICS workshop on clinical trial design for neurocognitive drugs for schizophrenia
-
Buchanan, R.W., Davis, M., Goff, D. et al. A summary of the FDA-NIMH-MATRICS workshop on clinical trial design for neurocognitive drugs for schizophrenia. Schizophr. Bull. 31, 5-19 (2005).
-
(2005)
Schizophr. Bull
, vol.31
, pp. 5-19
-
-
Buchanan, R.W.1
Davis, M.2
Goff, D.3
-
6
-
-
33744911665
-
Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia
-
Olincy, A., Harris, J.G., Johnson, L.L. et al. Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia. Arch. Gen. Psychiatry. 63, 630-638 (2006).
-
(2006)
Arch. Gen. Psychiatry
, vol.63
, pp. 630-638
-
-
Olincy, A.1
Harris, J.G.2
Johnson, L.L.3
-
7
-
-
0037604627
-
Muscarinic receptors as a target for drugs treating schizophrenia
-
Bymaster, F.P., Felder, C., Ahmed, S., and McKinzie, D. Muscarinic receptors as a target for drugs treating schizophrenia. Curr. Drug Targets CNS Neurol. Disord. 1, 163-181 (2002).
-
(2002)
Curr. Drug Targets CNS Neurol. Disord
, vol.1
, pp. 163-181
-
-
Bymaster, F.P.1
Felder, C.2
Ahmed, S.3
McKinzie, D.4
-
8
-
-
0034851624
-
Effects of ketamine in normal and schizophrenic volunteers
-
Lahti, A.C., Weiler, M.A., Tamara Michaelidis, B.A., Parwani, A., and Tamminga, C.A. Effects of ketamine in normal and schizophrenic volunteers. Neuropsychopharmacology 25, 455-467 (2001).
-
(2001)
Neuropsychopharmacology
, vol.25
, pp. 455-467
-
-
Lahti, A.C.1
Weiler, M.A.2
Tamara Michaelidis, B.A.3
Parwani, A.4
Tamminga, C.A.5
-
9
-
-
34948816146
-
Corrigenda: Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
-
Patil, S.T., Zhang, L., Martenyi, F. et al. Corrigenda: Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial. Nat. Med. 13, 1264 (2007).
-
(2007)
Nat. Med
, vol.13
, pp. 1264
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.3
-
10
-
-
0030902127
-
Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease
-
Boidick, N.C., Offen, W.W., Levey, A.I. et al. Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease. Arch. Neurol. 54, 465-473 (1997).
-
(1997)
Arch. Neurol
, vol.54
, pp. 465-473
-
-
Boidick, N.C.1
Offen, W.W.2
Levey, A.I.3
-
11
-
-
0030686570
-
The selective muscarinic agonist xanomeline improves both the cognitive deficits and behavioral symptoms of Alzheimer disease
-
Boidick, N.C., Offen, W.W., Shannon, H.E., Satterwhite, J., Lucas, R., Van Lier, R., and Paul, S.M. The selective muscarinic agonist xanomeline improves both the cognitive deficits and behavioral symptoms of Alzheimer disease. Alzheimer Dis. Assoc. Disord. 11, S16-22 (1997).
-
(1997)
Alzheimer Dis. Assoc. Disord
, vol.11
-
-
Boidick, N.C.1
Offen, W.W.2
Shannon, H.E.3
Satterwhite, J.4
Lucas, R.5
Van Lier, R.6
Paul, S.M.7
-
12
-
-
0031815934
-
Beyond the cholinergic hypothesis: The effect of metrifonate and other cholinesterase inhibitors on neuropsychiatric symptoms in Alzheimer's disease
-
Kaufer, D. Beyond the cholinergic hypothesis: The effect of metrifonate and other cholinesterase inhibitors on neuropsychiatric symptoms in Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 9, S8-S14 (1998).
-
(1998)
Dement. Geriatr. Cogn. Disord
, vol.9
-
-
Kaufer, D.1
-
13
-
-
0036996133
-
Treating Alzheimer's disease with cholinesterase inhibitors: What have we learned so far?
-
Feldman, H. Treating Alzheimer's disease with cholinesterase inhibitors: What have we learned so far? Int. Psychogeriatr. 14, S3-S5 (2002).
-
(2002)
Int. Psychogeriatr
, vol.14
-
-
Feldman, H.1
-
14
-
-
0036063168
-
The efficacy of cholinesterase inhibitors in treating the behavioral symptoms of dementia
-
Rosler, M. The efficacy of cholinesterase inhibitors in treating the behavioral symptoms of dementia. Int. J. Clin. Pract. Suppl. 127, 20-36 (2002).
-
(2002)
Int. J. Clin. Pract. Suppl
, vol.127
, pp. 20-36
-
-
Rosler, M.1
-
15
-
-
0036315509
-
Neuropsychiatric symptoms in the dementias
-
Assal, F. and Cummings, J.L. Neuropsychiatric symptoms in the dementias. Curr. Opin. Neurol. 15, 445-450 (2002).
-
(2002)
Curr. Opin. Neurol
, vol.15
, pp. 445-450
-
-
Assal, F.1
Cummings, J.L.2
-
16
-
-
0036992950
-
The ABC of Alzheimer's disease: Behavioral symptoms and their treatment
-
Grossberg, G.T. The ABC of Alzheimer's disease: Behavioral symptoms and their treatment. Int. Psychogeriatr. 14, S27-S49 (2002).
-
(2002)
Int. Psychogeriatr
, vol.14
-
-
Grossberg, G.T.1
-
17
-
-
0036040074
-
Rivastigmine for the treatment of dementia and visual hallucinations associated with Parkinson's disease: A case series
-
Bullock, R. and Cameron, A. Rivastigmine for the treatment of dementia and visual hallucinations associated with Parkinson's disease: A case series. Curr. Med. Res. Opin. 18, 258-264 (2002).
-
(2002)
Curr. Med. Res. Opin
, vol.18
, pp. 258-264
-
-
Bullock, R.1
Cameron, A.2
-
18
-
-
0041866256
-
Xanomeline and the antipsychotic potential of muscarinic receptor subtype selective agonists
-
Mirza ,N.R., Peters, D., and Sparks, R.G. Xanomeline and the antipsychotic potential of muscarinic receptor subtype selective agonists. CNS Drug Rev. 9, 159-186 (2003).
-
(2003)
CNS Drug Rev
, vol.9
, pp. 159-186
-
-
Mirza, N.R.1
Peters, D.2
Sparks, R.G.3
-
19
-
-
42249089469
-
-
Shekhar, A., Potter, W.Z., Lienemann, J., Sunblad, K., Lightfoot, J., Herrera, J., Unverzagt, F., Bymaster, F.P., and Felder, C.C. ACNP abstracts (2001).
-
(2001)
ACNP abstracts
-
-
Shekhar, A.1
Potter, W.Z.2
Lienemann, J.3
Sunblad, K.4
Lightfoot, J.5
Herrera, J.6
Unverzagt, F.7
Bymaster, F.P.8
Felder, C.C.9
-
20
-
-
0013888687
-
Ditran and its antagonists in a mixed psychiatric population
-
Neubauer, H., Sundland, D., and Gershon, S. Ditran and its antagonists in a mixed psychiatric population. J. Nerv. Ment. Dis. 142, 265-277 (1966).
-
(1966)
J. Nerv. Ment. Dis
, vol.142
, pp. 265-277
-
-
Neubauer, H.1
Sundland, D.2
Gershon, S.3
-
21
-
-
37249054670
-
-
Shirey, J.K., Xiang, Z., Orton, D. et al. An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission. Nature Chem. Biol. 4, 42-50 (2008).
-
Shirey, J.K., Xiang, Z., Orton, D. et al. An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission. Nature Chem. Biol. 4, 42-50 (2008).
-
-
-
-
22
-
-
0034811597
-
Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system
-
Schoepp, D.D. Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system. J. Pharmacol. Exp. Ther. 299, 12-20 (2001).
-
(2001)
J. Pharmacol. Exp. Ther
, vol.299
, pp. 12-20
-
-
Schoepp, D.D.1
-
23
-
-
0032886131
-
-
Schoepp, D.D., Monn, J.A., Marek, G.J., Aghajanian, G., and Moghaddam B. LY354740: A systemically active mGlu2/3 receptor agonist. CNS Drug Rev. 5, 1-12 (1999).
-
Schoepp, D.D., Monn, J.A., Marek, G.J., Aghajanian, G., and Moghaddam B. LY354740: A systemically active mGlu2/3 receptor agonist. CNS Drug Rev. 5, 1-12 (1999).
-
-
-
-
24
-
-
33846177868
-
Metabotropic glutamate receptors targets for neuropsychiatric disorders
-
Linden, A.M. and Schoepp, D.D. Metabotropic glutamate receptors targets for neuropsychiatric disorders. Drug Discov. Today 3, 507-517 (2006).
-
(2006)
Drug Discov. Today
, vol.3
, pp. 507-517
-
-
Linden, A.M.1
Schoepp, D.D.2
-
25
-
-
0032834028
-
Pharmacological agents acting at subtypes of metabotropic glutamate receptors
-
Schoepp, D.D., Jane, D.E., and Monn, J.A. Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology 38, 1431-1476 (1999).
-
(1999)
Neuropharmacology
, vol.38
, pp. 1431-1476
-
-
Schoepp, D.D.1
Jane, D.E.2
Monn, J.A.3
-
26
-
-
35448946953
-
Metabotropic glutamate receptor modulators: Recent advances and therapeutic potential
-
Monn, J.A. and Schoepp, D.D. (2000) Metabotropic glutamate receptor modulators: Recent advances and therapeutic potential. Ann. Rep. Med. Chem. 35, 1-10.
-
(2000)
Ann. Rep. Med. Chem
, vol.35
, pp. 1-10
-
-
Monn, J.A.1
Schoepp, D.D.2
-
27
-
-
0030852182
-
In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740
-
Battaglia, G., Monn, J.A., and Schoepp, D.D. In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740. Neuropsysiol. Clin. Neurosci. 229, 161-164 (1997).
-
(1997)
Neuropsysiol. Clin. Neurosci
, vol.229
, pp. 161-164
-
-
Battaglia, G.1
Monn, J.A.2
Schoepp, D.D.3
-
28
-
-
34948873609
-
Schizophrenia drug says goodbye to dopamine
-
Weinberger, D. Schizophrenia drug says goodbye to dopamine. Nature Med. 13, 1018-1019 (2007).
-
(2007)
Nature Med
, vol.13
, pp. 1018-1019
-
-
Weinberger, D.1
-
29
-
-
0032793383
-
NMDA-sensitive glutamate antagonism: A human model of psychosis
-
Lahti, A.C., Holcomb H.H., Gao X.-M., and Tamminga C.A. NMDA-sensitive glutamate antagonism: A human model of psychosis. Neuropsychopharmacology 21, S158-S169 (1999).
-
(1999)
Neuropsychopharmacology
, vol.21
-
-
Lahti, A.C.1
Holcomb, H.H.2
Gao, X.-M.3
Tamminga, C.A.4
-
30
-
-
0032785487
-
Therapeutic implications of the hyperglutamatergic effects of NMDA antagonists
-
Krystal, J.H., Belger, A., D'Souza, C., Anand, A., Charney, D.S., Aghajanian, G.K., and Moghaddam, B. Therapeutic implications of the hyperglutamatergic effects of NMDA antagonists. Neuropsychopharmacology 22, S143-S157 (1999).
-
(1999)
Neuropsychopharmacology
, vol.22
-
-
Krystal, J.H.1
Belger, A.2
D'Souza, C.3
Anand, A.4
Charney, D.S.5
Aghajanian, G.K.6
Moghaddam, B.7
-
31
-
-
0020629581
-
The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate
-
Anis, N.A., Berry, S.C., Burton,N.R., and Lodge, D. The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate. Br. J. Pharmacol. 79, 565-575 (1983).
-
(1983)
Br. J. Pharmacol
, vol.79
, pp. 565-575
-
-
Anis, N.A.1
Berry, S.C.2
Burton, N.R.3
Lodge, D.4
-
32
-
-
0032785165
-
Serotonin-glutamate interactions: A new target for antipsychotic drugs
-
Aghajanian, G.K. and Marek, G.J. Serotonin-glutamate interactions: A new target for antipsychotic drugs. Neuropsychopharmacology 21, S122-S133 (1999).
-
(1999)
Neuropsychopharmacology
, vol.21
-
-
Aghajanian, G.K.1
Marek, G.J.2
-
33
-
-
0011900802
-
Preclinical pharmacology of mGlu2/3 receptor agonists: Novel agents for schizophrenia?
-
Schoepp, D.D. and Marek, G.J. Preclinical pharmacology of mGlu2/3 receptor agonists: Novel agents for schizophrenia? Curr. Drug Targets CNS Neurol. Disord. 1, 215-225 (2002).
-
(2002)
Curr. Drug Targets CNS Neurol. Disord
, vol.1
, pp. 215-225
-
-
Schoepp, D.D.1
Marek, G.J.2
-
34
-
-
34948858402
-
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: Results from a phase 2 clinical trial
-
Patil, S.T., Zhang, L., Martenyi, F., Lowe, S., Jackson, K., Monn, J.A., Johnson, B.G., and Schoepp, D.D. Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: Results from a phase 2 clinical trial. Nature Med. 13, 1102-1107 (2007).
-
(2007)
Nature Med
, vol.13
, pp. 1102-1107
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.3
Lowe, S.4
Jackson, K.5
Monn, J.A.6
Johnson, B.G.7
Schoepp, D.D.8
-
35
-
-
0032575715
-
Reversal of phencyclidine effects by group II metabotropic glutamate receptor agonist in rats
-
Moghaddam, B. and Adams, B.W. Reversal of phencyclidine effects by group II metabotropic glutamate receptor agonist in rats. Science 281, 1349-1352 (1998).
-
(1998)
Science
, vol.281
, pp. 1349-1352
-
-
Moghaddam, B.1
Adams, B.W.2
-
36
-
-
0032848507
-
The mGlu2/3 agonists, LY354740 and LY379268, selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats
-
Cartmell J., Monn, J.A., and Schoepp, D.D. The mGlu2/3 agonists, LY354740 and LY379268, selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats. J. Pharmacol. Exp. Ther. 291, 161-170 (1999).
-
(1999)
J. Pharmacol. Exp. Ther
, vol.291
, pp. 161-170
-
-
Cartmell, J.1
Monn, J.A.2
Schoepp, D.D.3
-
37
-
-
34250162538
-
Pharmacological properties of a structurally-novel, potent, selective mGlu2/3 receptor agonist: In vivo characterization of LY404039 in animal models of psychiatric disorders
-
Rorick-Kehn, L.M., Johnson, B.G., Knitowski, K.M. et al. Pharmacological properties of a structurally-novel, potent, selective mGlu2/3 receptor agonist: In vivo characterization of LY404039 in animal models of psychiatric disorders. Psychopharmacology 193, 212-136 (2007).
-
(2007)
Psychopharmacology
, vol.193
, pp. 212-136
-
-
Rorick-Kehn, L.M.1
Johnson, B.G.2
Knitowski, K.M.3
-
38
-
-
42249103396
-
-
Fell, M.J., Svensson, K.A., Johnson, B.G., and Schoepp, D.D. Evidence for the role of mGlu2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist LY404039. J. Pharmacol. Exp. Ther. (2008).
-
Fell, M.J., Svensson, K.A., Johnson, B.G., and Schoepp, D.D. Evidence for the role of mGlu2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist LY404039. J. Pharmacol. Exp. Ther. (2008).
-
-
-
-
39
-
-
40449139964
-
Identification of a serotonin/ glutamate receptor complex implicated in psychosis
-
Gonzalez-Maeso J., Ang R.L., Yuen T. et al. Identification of a serotonin/ glutamate receptor complex implicated in psychosis. Nature 452, 93-97 (2008).
-
(2008)
Nature
, vol.452
, pp. 93-97
-
-
Gonzalez-Maeso, J.1
Ang, R.L.2
Yuen, T.3
-
40
-
-
0345830619
-
A role for noradrenergic neuronal transmission in the actions of phencyclidine and the antipsychotic and anti-stress effects of mGlu2/3 receptor agonists
-
Swanson, C.J. and Schoepp, D.D. A role for noradrenergic neuronal transmission in the actions of phencyclidine and the antipsychotic and anti-stress effects of mGlu2/3 receptor agonists. Ann. N.Y. Acad. Sci. 1003, 309-317 (2003).
-
(2003)
Ann. N.Y. Acad. Sci
, vol.1003
, pp. 309-317
-
-
Swanson, C.J.1
Schoepp, D.D.2
-
41
-
-
0033981186
-
Physiological antagonism between 5-hydroxytryptamine2A and group II metabotropic glutamate receptors in prefrontal cortex
-
Marek, G.J., Wright, R.A., Schoepp, D.D., Monn, J.A., and Aghajanian, G.K. Physiological antagonism between 5-hydroxytryptamine2A and group II metabotropic glutamate receptors in prefrontal cortex. J. Pharmacol. Exp. Ther. 292, 76-87 (2000).
-
(2000)
J. Pharmacol. Exp. Ther
, vol.292
, pp. 76-87
-
-
Marek, G.J.1
Wright, R.A.2
Schoepp, D.D.3
Monn, J.A.4
Aghajanian, G.K.5
-
42
-
-
33947415606
-
Pharmacological and pharmacokinetic properties of a structurally novel, potent, selective mGlu2/3 receptor agonist: In vitro characterization of LY404039
-
Rorick-Kehn, L.M., Johnson, B.G., Burkey, J.L. et al. Pharmacological and pharmacokinetic properties of a structurally novel, potent, selective mGlu2/3 receptor agonist: In vitro characterization of LY404039. J. Pharmacol. Exp. Ther. 321, 308-317 (2007).
-
(2007)
J. Pharmacol. Exp. Ther
, vol.321
, pp. 308-317
-
-
Rorick-Kehn, L.M.1
Johnson, B.G.2
Burkey, J.L.3
-
43
-
-
0028850552
-
Glutamate receptor dysfunction and schizophrenia
-
Olney, J.W. and Farber N.B. Glutamate receptor dysfunction and schizophrenia. Arch. Gen. Psychiatry 52, 998-1007 (1995).
-
(1995)
Arch. Gen. Psychiatry
, vol.52
, pp. 998-1007
-
-
Olney, J.W.1
Farber, N.B.2
-
44
-
-
1442333154
-
High-dose glycine added to olanzapine and risperidone for the treatment of schizophrenia
-
Heresco-Levy, U., Ermilov, M., Lichtenberg, P., Bar, G., and Javitt, D.C. High-dose glycine added to olanzapine and risperidone for the treatment of schizophrenia. Biol. Psychiatry 55, 165-171 (2004).
-
(2004)
Biol. Psychiatry
, vol.55
, pp. 165-171
-
-
Heresco-Levy, U.1
Ermilov, M.2
Lichtenberg, P.3
Bar, G.4
Javitt, D.C.5
-
45
-
-
0032694066
-
NMDA receptor hypofunction model of schizophrenia
-
Olney, J.W., Newcomer, J.W., and Farber, N.B. NMDA receptor hypofunction model of schizophrenia. J. Psychiatry Res. 33, 523-533 (1999).
-
(1999)
J. Psychiatry Res
, vol.33
, pp. 523-533
-
-
Olney, J.W.1
Newcomer, J.W.2
Farber, N.B.3
-
46
-
-
24644520313
-
-
Williams, D.L. and Jr., Lindsley, C.W. Discovery of positive allosteric modulators of metabotropic glutamate receptor subtype 5 (mGluR5). Curr. Topics Med. Chem. 5, 825-846 (2005).
-
Williams, D.L. and Jr., Lindsley, C.W. Discovery of positive allosteric modulators of metabotropic glutamate receptor subtype 5 (mGluR5). Curr. Topics Med. Chem. 5, 825-846 (2005).
-
-
-
-
47
-
-
0026772797
-
Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors
-
Smith, K.E., Borden, L.A., Hartig, P.R., Branchek, T., and Weinshank, R.L. Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors. Neuron 8, 927-935 (1992).
-
(1992)
Neuron
, vol.8
, pp. 927-935
-
-
Smith, K.E.1
Borden, L.A.2
Hartig, P.R.3
Branchek, T.4
Weinshank, R.L.5
-
48
-
-
0031730364
-
Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localization of the gene in the human genome
-
Morrow, J.A., Collie, I.T., Dunbar, D.R., Walker, G.B., Shahid, M., and Hill, D.R. Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localization of the gene in the human genome. FEBS Lett. 439, 334-340 (1998).
-
(1998)
FEBS Lett
, vol.439
, pp. 334-340
-
-
Morrow, J.A.1
Collie, I.T.2
Dunbar, D.R.3
Walker, G.B.4
Shahid, M.5
Hill, D.R.6
-
49
-
-
0029014595
-
Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS
-
Zafra, F., Gomeza, J., Olivares, L., Aragón, C., and Giménez, C. Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS. Eur. J. Neurosci. 7, 1342-1352 (1995).
-
(1995)
Eur. J. Neurosci
, vol.7
, pp. 1342-1352
-
-
Zafra, F.1
Gomeza, J.2
Olivares, L.3
Aragón, C.4
Giménez, C.5
-
50
-
-
0035206917
-
ALX 5407: A potent, selective inhibitor of the hGlyT1 glycine transporter
-
Atkinson, B.N., Bell, S.C., and De Vivo, M. ALX 5407: A potent, selective inhibitor of the hGlyT1 glycine transporter. Mol. Pharm. 60, 1414-1420 (2001).
-
(2001)
Mol. Pharm
, vol.60
, pp. 1414-1420
-
-
Atkinson, B.N.1
Bell, S.C.2
De Vivo, M.3
-
51
-
-
2642557822
-
The therapeutic potential of glycine transporter-1 inhibitors
-
Sur, C. and Kinney, G.G. The therapeutic potential of glycine transporter-1 inhibitors. Expert. Opin. Investig. Drugs 13, 515-521 (2004).
-
(2004)
Expert. Opin. Investig. Drugs
, vol.13
, pp. 515-521
-
-
Sur, C.1
Kinney, G.G.2
-
52
-
-
27944442703
-
Discovery of N-(2-hydroxy-2-aryl-cyclohexyl) substituted spiropiperidines as GlyT1 antagonists with improved pharmacological profile
-
Ceccarelli, S.M., Pinard, E., Stadler, H., and Alberati, D. Discovery of N-(2-hydroxy-2-aryl-cyclohexyl) substituted spiropiperidines as GlyT1 antagonists with improved pharmacological profile. Bioorg. Med. Chem. Lett. 16, 354-357 (2005).
-
(2005)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 354-357
-
-
Ceccarelli, S.M.1
Pinard, E.2
Stadler, H.3
Alberati, D.4
-
53
-
-
10744226185
-
Development of a scintillation proximity assay for analysis of Na+/Cl- -dependent neurotransmitter transporter activity
-
Williams, J.B., Mallorga, P.J., Lemaire, W. et al. Development of a scintillation proximity assay for analysis of Na+/Cl- -dependent neurotransmitter transporter activity. Anal. Biochem. 321, 31-37 (2003).
-
(2003)
Anal. Biochem
, vol.321
, pp. 31-37
-
-
Williams, J.B.1
Mallorga, P.J.2
Lemaire, W.3
-
54
-
-
33748667527
-
Design, synthesis, and in vivo efficacy of glycine transporter-1 (GlyT1) inhibitors derived from a series of [4-phenyl-1-(propylsulfonyl)piperidin-4-yl]methyl benzamides
-
Lindsley, C.W., Zhao, Z., Leister, W.H. et al. Design, synthesis, and in vivo efficacy of glycine transporter-1 (GlyT1) inhibitors derived from a series of [4-phenyl-1-(propylsulfonyl)piperidin-4-yl]methyl benzamides. ChemMedChem 1, 807-811 (2006).
-
(2006)
ChemMedChem
, vol.1
, pp. 807-811
-
-
Lindsley, C.W.1
Zhao, Z.2
Leister, W.H.3
-
55
-
-
40749086417
-
A novel radioligand for glycine transporter 1: Characterization and use in autoradiographic and in vivo brain occupancy studies
-
Zeng, Z., O'Brien, J.A., Lemaire, W., O'Malley, S.S. et al. A novel radioligand for glycine transporter 1: Characterization and use in autoradiographic and in vivo brain occupancy studies. Nuc. Med. Biol. 35, 315-325 (2008).
-
(2008)
Nuc. Med. Biol
, vol.35
, pp. 315-325
-
-
Zeng, Z.1
O'Brien, J.A.2
Lemaire, W.3
O'Malley, S.S.4
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