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Volumn 21, Issue 2, 2009, Pages 153-167

Thioredoxin mediates remodeling factors of human bronchial epithelial cells upon interaction with house dust mite-stimulated eosinophils

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE B; HOUSE DUST ALLERGEN; INTERLEUKIN 6; PROTEINASE; REACTIVE OXYGEN METABOLITE; THIOREDOXIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

EID: 60749104753     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.1080/08958370802368730     Document Type: Article
Times cited : (15)

References (63)
  • 1
    • 33646368158 scopus 로고    scopus 로고
    • The house dust mite allergen Der p1, unlike Der p3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism
    • Adam, E., Hansen, K. K., Astudillo Fernandez, O., Coulon, L., Bex, F., Duhant, X., Jaumotte, E., Hollenberg, M. D., and Jacquet, A. 2006. The house dust mite allergen Der p1, unlike Der p3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism. J. Biol. Chem. 281:6910-6923.
    • (2006) J. Biol. Chem , vol.281 , pp. 6910-6923
    • Adam, E.1    Hansen, K.K.2    Astudillo Fernandez, O.3    Coulon, L.4    Bex, F.5    Duhant, X.6    Jaumotte, E.7    Hollenberg, M.D.8    Jacquet, A.9
  • 3
    • 0033775891 scopus 로고    scopus 로고
    • Physiological functions of thioredoxin and thioredoxin reductase
    • Arner, E. S., and Holmgren, A. 2000. Physiological functions of thioredoxin and thioredoxin reductase. Eur. J. Biochem. 267:6102-6109.
    • (2000) Eur. J. Biochem , vol.267 , pp. 6102-6109
    • Arner, E.S.1    Holmgren, A.2
  • 4
    • 0036246458 scopus 로고    scopus 로고
    • The burden of asthma with specific reference to the United States
    • Beasley, R. 2002. The burden of asthma with specific reference to the United States. J. Allergy Clin. Immunol. 109:S482-S489.
    • (2002) J. Allergy Clin. Immunol , vol.109
    • Beasley, R.1
  • 5
    • 0032516898 scopus 로고    scopus 로고
    • Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells
    • Bellido, T., O'Brien, C. A., Roberson, P. K., and Manolagas, S. C. 1998. Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells. J. Biol. Chem. 273:21137-21144.
    • (1998) J. Biol. Chem , vol.273 , pp. 21137-21144
    • Bellido, T.1    O'Brien, C.A.2    Roberson, P.K.3    Manolagas, S.C.4
  • 7
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor-β in human disease
    • Blobe, G. C., Schiemann, W. P., and Lodish, H. F. 2000. Role of transforming growth factor-β in human disease. New Engl. J. Med. 342:1350-1358.
    • (2000) New Engl. J. Med , vol.342 , pp. 1350-1358
    • Blobe, G.C.1    Schiemann, W.P.2    Lodish, H.F.3
  • 12
    • 2542486456 scopus 로고    scopus 로고
    • Asthma: Mechanisms of disease persistence and progression
    • Cohn, L., Elias, J. A., and Chupp, G. L. 2004. Asthma: Mechanisms of disease persistence and progression. Annu. Rev. Immunol. 22:789-815.
    • (2004) Annu. Rev. Immunol , vol.22 , pp. 789-815
    • Cohn, L.1    Elias, J.A.2    Chupp, G.L.3
  • 13
    • 3242745070 scopus 로고    scopus 로고
    • Allergen activates peripheral blood eosinophil nuclear factor-κB to generate granulocyte macrophage-colony stimulating factor, tumor necrosis factor-α, and interleukin-8
    • Coward, W. R., Sagara, H., Wilson, S. J., Holgate, S. T., and Church, M. K. 2004. Allergen activates peripheral blood eosinophil nuclear factor-κB to generate granulocyte macrophage-colony stimulating factor, tumor necrosis factor-α, and interleukin-8. Clin. Exp. Allergy 34:1071-1078.
    • (2004) Clin. Exp. Allergy , vol.34 , pp. 1071-1078
    • Coward, W.R.1    Sagara, H.2    Wilson, S.J.3    Holgate, S.T.4    Church, M.K.5
  • 14
    • 0033797637 scopus 로고    scopus 로고
    • Oxidant stress in asthma
    • Dworski, R. 2002. Oxidant stress in asthma. Thorax 55:S51-53.
    • (2002) Thorax , vol.55
    • Dworski, R.1
  • 15
    • 35948950217 scopus 로고    scopus 로고
    • A heparan sulfate-facilitated and raft-dependent macropinocytosis of eosinophil cationic protein
    • Fan, T. C., Chang, H. T., Chen, I. W., Wang, H. Y., and Chang, M. D. 2007. A heparan sulfate-facilitated and raft-dependent macropinocytosis of eosinophil cationic protein. Traffic 8:778-1795.
    • (2007) Traffic , vol.8 , pp. 778-1795
    • Fan, T.C.1    Chang, H.T.2    Chen, I.W.3    Wang, H.Y.4    Chang, M.D.5
  • 16
    • 18844401152 scopus 로고    scopus 로고
    • Epithelial stress and structural remodeling in childhood asthma
    • Fedorov, I. A., Wilson, S. J., Davies, D. E., and Holgate, S. T. 2005. Epithelial stress and structural remodeling in childhood asthma. Thorax 60:389-394.
    • (2005) Thorax , vol.60 , pp. 389-394
    • Fedorov, I.A.1    Wilson, S.J.2    Davies, D.E.3    Holgate, S.T.4
  • 17
    • 0036594890 scopus 로고    scopus 로고
    • The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
    • Gartel, A. L., and Tyner, A. L. 2002. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol. Cancer Ther. 1:639-649.
    • (2002) Mol. Cancer Ther , vol.1 , pp. 639-649
    • Gartel, A.L.1    Tyner, A.L.2
  • 18
    • 0033006040 scopus 로고    scopus 로고
    • Pharmacology of the eosinophil
    • Giembycz, M. A., and Lindsay, M. A. 1999. Pharmacology of the eosinophil. Pharmacol. Rev. 51:213-340.
    • (1999) Pharmacol. Rev , vol.51 , pp. 213-340
    • Giembycz, M.A.1    Lindsay, M.A.2
  • 19
    • 25844447623 scopus 로고    scopus 로고
    • Eosinophil-fibroblast interactions induce fibroblast IL-6 secretion and extracellular matrix gene expression: Implications in fibrogenesis
    • Gomes, I., Mathur, S. K., Espenshade, B. M., Mori, Y., Varga, J., and Ackerman, S. J. 2005. Eosinophil-fibroblast interactions induce fibroblast IL-6 secretion and extracellular matrix gene expression: Implications in fibrogenesis. J. Allergy Clin. Immunol. 116:796-804.
    • (2005) J. Allergy Clin. Immunol , vol.116 , pp. 796-804
    • Gomes, I.1    Mathur, S.K.2    Espenshade, B.M.3    Mori, Y.4    Varga, J.5    Ackerman, S.J.6
  • 21
    • 33144490305 scopus 로고    scopus 로고
    • Nuclear and mitochondrial compartmentation of oxidative stress and redox signaling
    • Hansen, J. M., Go, Y. M., and Jones, D. P. 2006. Nuclear and mitochondrial compartmentation of oxidative stress and redox signaling. Annu. Rev. Pharmacol. Toxicol. 46:215-234.
    • (2006) Annu. Rev. Pharmacol. Toxicol , vol.46 , pp. 215-234
    • Hansen, J.M.1    Go, Y.M.2    Jones, D.P.3
  • 23
    • 0031957991 scopus 로고    scopus 로고
    • Expression of growth factors and remodeling of the airway wall in bronchial asthma
    • Hoshino, M., Nakamura, Y., and Sim, J. J. 1998. Expression of growth factors and remodeling of the airway wall in bronchial asthma. Thorax 53:21-27.
    • (1998) Thorax , vol.53 , pp. 21-27
    • Hoshino, M.1    Nakamura, Y.2    Sim, J.J.3
  • 26
    • 0024578295 scopus 로고
    • The mechanics of airway narrowing in asthma
    • James, A. L., Pare, P. D., and Hogg, J. C. 1989. The mechanics of airway narrowing in asthma. Am. Rev. Respir. Dis. 139:242-246.
    • (1989) Am. Rev. Respir. Dis , vol.139 , pp. 242-246
    • James, A.L.1    Pare, P.D.2    Hogg, J.C.3
  • 27
    • 27844518302 scopus 로고    scopus 로고
    • Thioredoxin-1 suppresses lung injury and apoptosis induced by diesel exhaust particles (DEP) by scavenging reactive oxygen species and by inhibiting DEP-induced down-regulation of Akt
    • Kaimul Ahsan, M., Nakamura, H., Tanito, M., Yamada, K., Utsumi, H., and Yodoi. J. 2005. Thioredoxin-1 suppresses lung injury and apoptosis induced by diesel exhaust particles (DEP) by scavenging reactive oxygen species and by inhibiting DEP-induced down-regulation of Akt. Free Radic. Biol. Med. 39:1549-1559.
    • (2005) Free Radic. Biol. Med , vol.39 , pp. 1549-1559
    • Kaimul Ahsan, M.1    Nakamura, H.2    Tanito, M.3    Yamada, K.4    Utsumi, H.5    Yodoi, J.6
  • 28
    • 0029991462 scopus 로고    scopus 로고
    • The house dust mite allergen Der p1 catalytically inactivates α1-antitrypsin by specific reactive centre loop cleavage: A mechanism that promotes airway inflammation and asthma
    • Kalsheker, N. A., Deam, S., Chambers, L., Sreedharan, S., Brocklehurst, K., and Lomas, D. A. 1996. The house dust mite allergen Der p1 catalytically inactivates α1-antitrypsin by specific reactive centre loop cleavage: A mechanism that promotes airway inflammation and asthma. Biochem. Biophys. Res. Commun. 221:59-61.
    • (1996) Biochem. Biophys. Res. Commun , vol.221 , pp. 59-61
    • Kalsheker, N.A.1    Deam, S.2    Chambers, L.3    Sreedharan, S.4    Brocklehurst, K.5    Lomas, D.A.6
  • 29
    • 0032193198 scopus 로고    scopus 로고
    • Dust mite proteolytic allergens induce cytokine release from cultured airway epithelium
    • King, C., Brennan, S., Thompson, P. J., and Stewart, G. A. 1998. Dust mite proteolytic allergens induce cytokine release from cultured airway epithelium. J. Immunol. 161:3645-3651.
    • (1998) J. Immunol , vol.161 , pp. 3645-3651
    • King, C.1    Brennan, S.2    Thompson, P.J.3    Stewart, G.A.4
  • 30
    • 0034574298 scopus 로고    scopus 로고
    • How cells read TGF-beta signals
    • Massagué, J. 2000. How cells read TGF-beta signals. Nat. Rev. Mol. Cell Biol. 1:169-178.
    • (2000) Nat. Rev. Mol. Cell Biol , vol.1 , pp. 169-178
    • Massagué, J.1
  • 31
    • 22744443858 scopus 로고    scopus 로고
    • The thioredoxin system in retroviral infection and apoptosis
    • Masutani, H., Ueda, S., and Yodoi, J. 2005. The thioredoxin system in retroviral infection and apoptosis. Cell Death Differ. 12:991-998.
    • (2005) Cell Death Differ , vol.12 , pp. 991-998
    • Masutani, H.1    Ueda, S.2    Yodoi, J.3
  • 32
    • 0037391735 scopus 로고    scopus 로고
    • Human eosinophils are activated by cysteine proteases and release inflammatory mediators
    • Miike, S., and Kita, H. 2003. Human eosinophils are activated by cysteine proteases and release inflammatory mediators. J. Allergy Clin. Immunol. 111:704-713.
    • (2003) J. Allergy Clin. Immunol , vol.111 , pp. 704-713
    • Miike, S.1    Kita, H.2
  • 34
    • 22744452759 scopus 로고    scopus 로고
    • Involvement of EGF receptor and c-Src in the survival signals induced by TGF-β1 inhepatocytes
    • Murillo, M. M., del Castillo, G., Sánchez, A., Fernández, M., and Fabregat, I. 2005. Involvement of EGF receptor and c-Src in the survival signals induced by TGF-β1 inhepatocytes. Oncogene 24:4580-4587.
    • (2005) Oncogene , vol.24 , pp. 4580-4587
    • Murillo, M.M.1    del Castillo, G.2    Sánchez, A.3    Fernández, M.4    Fabregat, I.5
  • 35
  • 36
    • 24644520068 scopus 로고    scopus 로고
    • Airway remodeling contributes to the progressive loss of lung function in asthma: An overview
    • Pascual, R. M., and Peters, S. P. 2005. Airway remodeling contributes to the progressive loss of lung function in asthma: An overview. J. Allergy Clin. Immunol. 116:477-486.
    • (2005) J. Allergy Clin. Immunol , vol.116 , pp. 477-486
    • Pascual, R.M.1    Peters, S.P.2
  • 37
    • 33749143444 scopus 로고    scopus 로고
    • Eosinophil-derived cationic proteins activate the synthesis of remodeling factors by airway epithelial cells
    • Pegorier, S., Wagner, L. A., Gleich, G. J., and Pretolani, M. 2006. Eosinophil-derived cationic proteins activate the synthesis of remodeling factors by airway epithelial cells. J. Immunol. 177:4861-4869.
    • (2006) J. Immunol , vol.177 , pp. 4861-4869
    • Pegorier, S.1    Wagner, L.A.2    Gleich, G.J.3    Pretolani, M.4
  • 38
    • 33644781601 scopus 로고    scopus 로고
    • Oxidant and antioxidant balance in the airways and airway diseases
    • Rahman, I., Biswas, S. K., and Kode, A. 2006. Oxidant and antioxidant balance in the airways and airway diseases. Eur. J. Pharmacol. 533:222-239.
    • (2006) Eur. J. Pharmacol , vol.533 , pp. 222-239
    • Rahman, I.1    Biswas, S.K.2    Kode, A.3
  • 39
    • 0030828035 scopus 로고    scopus 로고
    • Immunoreactive endothelin in bronchial biopsy specimens: Increased expression in asthma and modulation by corticosteroid therapy
    • Redington, A. E., Springall, D. R., Meng, Q. H., Tuck, A. B., Holgate, S. T., Polak, J. M., and Howarth, P. H. 1997. Immunoreactive endothelin in bronchial biopsy specimens: Increased expression in asthma and modulation by corticosteroid therapy. J. Allergy Clin. Immunol. 100:544-552.
    • (1997) J. Allergy Clin. Immunol , vol.100 , pp. 544-552
    • Redington, A.E.1    Springall, D.R.2    Meng, Q.H.3    Tuck, A.B.4    Holgate, S.T.5    Polak, J.M.6    Howarth, P.H.7
  • 44
    • 45149093853 scopus 로고    scopus 로고
    • MMP-14 mediated MMP-9 expression is involved in TGF-beta1-induced keratinocyte migration
    • Seomun, Y., Kim, J. T., and Joo, C. K. 2008. MMP-14 mediated MMP-9 expression is involved in TGF-beta1-induced keratinocyte migration. J. Cell. Biochem. 104:934-941.
    • (2008) J. Cell. Biochem , vol.104 , pp. 934-941
    • Seomun, Y.1    Kim, J.T.2    Joo, C.K.3
  • 45
    • 33745760717 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-mediated proliferation of enterocytes requires p21waf1/cip1 expression
    • Sheng, G., Bernabe, K. Q., Guo, J., and Warner, B. W. 2006. Epidermal growth factor receptor-mediated proliferation of enterocytes requires p21waf1/cip1 expression. Gastroenterology 131:153-164.
    • (2006) Gastroenterology , vol.131 , pp. 153-164
    • Sheng, G.1    Bernabe, K.Q.2    Guo, J.3    Warner, B.W.4
  • 46
    • 0025299641 scopus 로고
    • Tumor necrosis factor-α/cachectin stimulates eosinophil oxidant production and toxicity towards human endothelium
    • Slungaard, A., Vercellotti, G. M., Walker, G., Nelson, R. D., and Jacob, H. S. 1990. Tumor necrosis factor-α/cachectin stimulates eosinophil oxidant production and toxicity towards human endothelium. J. Exp. Med. 171:2025-2041.
    • (1990) J. Exp. Med , vol.171 , pp. 2025-2041
    • Slungaard, A.1    Vercellotti, G.M.2    Walker, G.3    Nelson, R.D.4    Jacob, H.S.5
  • 47
    • 0031577276 scopus 로고    scopus 로고
    • The allergen Der p1 induces NF-κB activation through interference with IκBα function in asthmatic bronchial epithelial cells
    • Stacey, M. A., Sun, G., Vassalli, G., Marini, M., Bellini, A., and Mattoli, S. 1997. The allergen Der p1 induces NF-κB activation through interference with IκBα function in asthmatic bronchial epithelial cells. Biochem. Biophys. Res. Commun. 236:522-526.
    • (1997) Biochem. Biophys. Res. Commun , vol.236 , pp. 522-526
    • Stacey, M.A.1    Sun, G.2    Vassalli, G.3    Marini, M.4    Bellini, A.5    Mattoli, S.6
  • 48
    • 3242684537 scopus 로고    scopus 로고
    • Allergen extracts directly mobilize and activate human eosinophils
    • Svensson, L., Rudin, A., and Wenneras, C. 2004. Allergen extracts directly mobilize and activate human eosinophils. Eur. J. Immunol. 34:1744-1751.
    • (2004) Eur. J. Immunol , vol.34 , pp. 1744-1751
    • Svensson, L.1    Rudin, A.2    Wenneras, C.3
  • 52
    • 35148856206 scopus 로고    scopus 로고
    • Allergen induced gene expression of airway epithelial cells shows a possible role for TNF-alpha
    • Vroling, A. B., Duinsbergen, D., Fokkens, W. J., and van Drunen, C. M. 2007. Allergen induced gene expression of airway epithelial cells shows a possible role for TNF-alpha.Allergy 62:1310-1319.
    • (2007) Allergy , vol.62 , pp. 1310-1319
    • Vroling, A.B.1    Duinsbergen, D.2    Fokkens, W.J.3    van Drunen, C.M.4
  • 53
    • 0035726360 scopus 로고    scopus 로고
    • Eosinophil-epithelial cell interactions: A special relationship?
    • Walsh, G. M. 2001. Eosinophil-epithelial cell interactions: A special relationship? Clin. Exp. Allergy 31:351-354.
    • (2001) Clin. Exp. Allergy , vol.31 , pp. 351-354
    • Walsh, G.M.1
  • 54
    • 0035086672 scopus 로고    scopus 로고
    • The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from fecal pellets of Dermatophagoides pteronyssinus
    • Wan, H., Winton, H. L., Soeller, C., Taylor, G. W., Gruenert, D. C., Thompson, P. J., Cannell, M. B., Stewart, G. A., Garrod, D. R., and Robinson, C. 2001. The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from fecal pellets of Dermatophagoides pteronyssinus. Clin. Exp. Allergy 31:279-294.
    • (2001) Clin. Exp. Allergy , vol.31 , pp. 279-294
    • Wan, H.1    Winton, H.L.2    Soeller, C.3    Taylor, G.W.4    Gruenert, D.C.5    Thompson, P.J.6    Cannell, M.B.7    Stewart, G.A.8    Garrod, D.R.9    Robinson, C.10
  • 55
    • 36549015177 scopus 로고    scopus 로고
    • Repeated instillations of Dermatophagoides farinae into the airways can induce Th2-dependent airway hyperresponsiveness, eosinophilia and remodeling in mice: Effect of intratracheal treatment of fluticasone propionate
    • Wakahara, K., Tanaka, H., Takahashi, G., Tamari, M., Nasu, R., Toyohara, T., Takano, H., Saito, S., Inagaki, N., Shimokata, K., and Nagai, H. 2008. Repeated instillations of Dermatophagoides farinae into the airways can induce Th2-dependent airway hyperresponsiveness, eosinophilia and remodeling in mice: effect of intratracheal treatment of fluticasone propionate. Eur. J. Pharmacol. 578:87-96.
    • (2008) Eur. J. Pharmacol , vol.578 , pp. 87-96
    • Wakahara, K.1    Tanaka, H.2    Takahashi, G.3    Tamari, M.4    Nasu, R.5    Toyohara, T.6    Takano, H.7    Saito, S.8    Inagaki, N.9    Shimokata, K.10    Nagai, H.11
  • 57
    • 0034882184 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and TH cytokines (IFNγ, IL-4, IL-10, and IL-13) in patients with allergic asthma
    • Wong, C. K., Ho, C. Y., Ko, F. W., Chan, C. H., Ho, A. S., Hui, D. S., and Lam, C. W. 2001. Pro-inflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and TH cytokines (IFNγ, IL-4, IL-10, and IL-13) in patients with allergic asthma. Clin. Exp. Immunol. 125:177-183.
    • (2001) Clin. Exp. Immunol , vol.125 , pp. 177-183
    • Wong, C.K.1    Ho, C.Y.2    Ko, F.W.3    Chan, C.H.4    Ho, A.S.5    Hui, D.S.6    Lam, C.W.7
  • 58
    • 33748445862 scopus 로고    scopus 로고
    • House dust mite allergen Der p1 elevates the release of inflammatory cytokines and expression of adhesion molecules in co-culture of human eosinophils and bronchial epithelial cells
    • Wong, C. K., Li, M. L., Wang, C. B., Ip, W. K., Tian, Y. P., and Lam, C. W. 2006. House dust mite allergen Der p1 elevates the release of inflammatory cytokines and expression of adhesion molecules in co-culture of human eosinophils and bronchial epithelial cells. Int. Immunol. 18:1327-1335.
    • (2006) Int. Immunol , vol.18 , pp. 1327-1335
    • Wong, C.K.1    Li, M.L.2    Wang, C.B.3    Ip, W.K.4    Tian, Y.P.5    Lam, C.W.6
  • 61
    • 37349030155 scopus 로고    scopus 로고
    • Airway remodeling in asthma and irreversible airflow limitation-ECM deposition in airway and possible therapy for remodeling
    • Yamauchi, K., and Inoue, H. 2007. Airway remodeling in asthma and irreversible airflow limitation-ECM deposition in airway and possible therapy for remodeling. Allergol. Int. 56:321-329.
    • (2007) Allergol. Int , vol.56 , pp. 321-329
    • Yamauchi, K.1    Inoue, H.2
  • 62
    • 38449100323 scopus 로고    scopus 로고
    • Protective role of matrix metalloproteinase-9 in ozone-induced airway inflammation
    • Yoon, H. K., Cho, H. Y., and Kleeberger, S. R. 2007. Protective role of matrix metalloproteinase-9 in ozone-induced airway inflammation. Environ. Health Persp. 115:1557-1563.
    • (2007) Environ. Health Persp , vol.115 , pp. 1557-1563
    • Yoon, H.K.1    Cho, H.Y.2    Kleeberger, S.R.3
  • 63
    • 0033168698 scopus 로고    scopus 로고
    • Involvement of thioredoxin in rheumatoid arthritis: Its costimulatory roles in the TNFα-induced production of IL-6 and IL-8 from cultured synovial fibroblasts
    • Yoshida, S., Katoh, T., Tetsuka, T., Uno, K., Matsui, N., and Okamoto, T. 1999. Involvement of thioredoxin in rheumatoid arthritis: Its costimulatory roles in the TNFα-induced production of IL-6 and IL-8 from cultured synovial fibroblasts. J. Immunol. 163:351-358.
    • (1999) J. Immunol , vol.163 , pp. 351-358
    • Yoshida, S.1    Katoh, T.2    Tetsuka, T.3    Uno, K.4    Matsui, N.5    Okamoto, T.6


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