Effects of thioredoxin on established airway remodeling in a chronic antigen exposure asthma model

Biochemical and Biophysical Research Communications

Volumn 360, Issue 3, 2007, Pages 525-530

  Imaoka, Haruki ^a   Hoshino, Tomoaki ^a   Takei, Satoko ^a   Sakazaki, Yuki ^a   Kinoshita, Takashi ^a   Okamoto, Masaki ^a   Kawayama, Tomotaka ^a   Yodoi, Junji ^b   Kato, Seiya ^c   Iwanaga, Tomoaki ^a   Aizawa, Hisamichi ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

Asthma; Chemokines; Remodeling; Th2 cytokines; Transgenic mouse

Indexed keywords

ANTIGEN; CHEMOKINE; CYTOKINE; EOTAXIN; INTERLEUKIN 13; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; OVALBUMIN; THIOREDOXIN; THIOREDOXIN 1; UNCLASSIFIED DRUG;

AIRWAY; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BAGG ALBINO MOUSE; DRUG EFFECT; EOSINOPHILIA; FEMALE; LUNG; MOUSE; NONHUMAN; PATHOLOGY; PNEUMONIA; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; TRANSGENIC MOUSE;

ANIMALS; ASTHMA; BRONCHI; CHEMOKINES, CC; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; HUMANS; INTERLEUKIN-13; LUNG; MACROPHAGE INFLAMMATORY PROTEIN-1; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MUSCLE, SMOOTH; OVALBUMIN; PNEUMONIA; THIOREDOXIN; TIME;

MUS; MUS MUSCULUS;

EID: 34447277917     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.06.019     Document Type: Article

References (21)

1. Ebina M., Takahashi T., Chiba T., and Motomiya M. Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma. A 3-D morphometric study. Am. Rev. Respir. Dis. 148 (1993) 720-726
2. Payne D.N., Rogers A.V., Adelroth E., Bandi V., Guntupalli K.K., Bush A., and Jeffery P.K. Early thickening of the reticular basement membrane in children with difficult asthma. Am. J. Respir. Crit. Care. Med. 167 (2003) 78-82
3. Benayoun L., Druilhe A., Dombret M.C., Aubier M., and Pretolani M. Airway structural alterations selectively associated with severe asthma. Am. J. Respir. Crit. Care. Med. 167 (2003) 1360-1368
4. Rennard S.I. Repair mechanisms in asthma. J. Allergy Clin. Immunol. 98 (1996) S278-S286
5. Barnes P.J. Cytokine-directed therapies for the treatment of chronic airway diseases. Cytokine Growth Factor Rev. 14 (2003) 511-522
6. Holmgren A. Thioredoxin. Annu. Rev. Biochem. 54 (1985) 237-271
7. Nakamura H., Nakamura K., and Yodoi J. Redox regulation of cellular activation. Annu. Rev. Immunol. 15 (1997) 351-369
8. Nakamura T., Nakamura H., Hoshino T., Ueda S., Wada H., and Yodoi J. Redox regulation of lung inflammation by thioredoxin. Antioxid Redox Signal 7 (2005) 60-71
9. Okamoto M., Kato S., Oizumi K., Kinoshita M., Inoue Y., Hoshino K., Akira S., McKenzie A.N., Young H.A., and Hoshino T. Interleukin 18 (IL-18) in synergy with IL-2 induces lethal lung injury in mice: a potential role for cytokines, chemokines, and natural killer cells in the pathogenesis of interstitial pneumonia. Blood 99 (2002) 1289-1298
10. Hoshino T., Nakamura H., Okamoto M., Kato S., Araya S., Nomiyama K., Oizumi K., Young H.A., Aizawa H., and Yodoi J. Redox-active protein thioredoxin prevents proinflammatory cytokine- or bleomycin-induced lung injury. Am. J. Respir. Crit. Care Med. 168 (2003) 1075-1083
11. Ichiki H., Hoshino T., Kinoshita T., Imaoka H., Kato S., Inoue H., Nakamura H., Yodoi J., Young H.A., and Aizawa H. Thioredoxin suppresses airway hyperresponsiveness and airway inflammation in asthma. Biochem. Biophys. Res. Commun. 334 (2005) 1141-1148
12. Kinoshita T., Hoshino T., Imaoka H., Ichiki H., Okamoto M., Kawayama T., Yodoi J., Kato S., and Aizawa H. Thioredoxin prevents the development and progression of elastase-induced emphysema. Biochem. Biophys. Res. Commun. 354 (2007) 712-719
13. Hoshino T., Kato S., Oka N., Imaoka H., Kinoshita T., Takei S., Kitasato Y., Kawayama T., Imaizumi T., Yamada K., Young H.A., and Aizawa H. Pulmonary inflammation and emphysema: role of the cytokines IL-18 and IL-13. Am. J. Respir. Crit. Care. Med. 176 (2007) 49-62
14. Hamelmann E., Schwarze J., Takeda K., Oshiba A., Larsen G.L., Irvin C.G., and Gelfand E.W. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am. J. Respir. Crit. Care Med. 156 (1997) 766-775
15. Wang C.G., Du T., Xu L.J., and Martin J.G. Role of leukotriene D4 in allergen-induced increases in airway smooth muscle in the rat. Am. Rev. Respir. Dis. 148 (1993) 413-417
16. Blyth D.I., Wharton T.F., Pedrick M.S., Savage T.J., and Sanjar S. Airway subepithelial fibrosis in a murine model of atopic asthma: suppression by dexamethasone or anti-interleukin-5 antibody. Am. J. Respir. Cell. Mol. Biol. 23 (2000) 241-246
17. Christie P.E., Jonas M., Tsai C.H., Chi E.Y., and Henderson Jr. W.R. Increase in laminin expression in allergic airway remodelling and decrease by dexamethasone. Eur. Respir. J. 24 (2004) 107-115
18. Vanacker N.J., Palmans E., Kips J.C., and Pauwels R.A. Fluticasone inhibits but does not reverse allergen-induced structural airway changes. Am. J. Respir. Crit. Care Med. 163 (2001) 674-679
19. Henderson Jr. W.R., Chiang G.K., Tien Y.T., and Chi E.Y. Reversal of allergen-induced airway remodeling by CysLT1 receptor blockade. Am. J. Respir. Crit. Care Med. 173 (2006) 718-728
20. Busse W., Banks-Schlegel S., Noel P., Ortega H., Taggart V., and Elias J. Future research directions in asthma: an NHLBI Working Group report. Am J. Respir Crit Care Med 170 (2004) 683-690
21. Inman M. Is there a place for anti-remodelling drugs in asthma which may not display immediate clinical efficacy?. Eur. Respir. J. 24 (2004) 1-2