Metabolic evolution suggests an explanation for the weakness of antioxidant defences in beta-cells

Mechanisms of Ageing and Development

Volumn 130, Issue 4, 2009, Pages 216-221

  Rashidi, Armin ^a   Kirkwood, Thomas B L ^a   Shanley, Daryl P ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Antioxidant; Beta cell; Brain; Evolution; Insulin resistance; Stress

Indexed keywords

REACTIVE OXYGEN METABOLITE; STRESS HORMONE;

ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN; DOWN REGULATION; FETUS (ANATOMY); GLUCOSE BLOOD LEVEL; HOMEOSTASIS; HORMONE RELEASE; HUMAN; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SYNTHESIS; NATURAL SELECTION; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RESOURCE ALLOCATION; THIRD TRIMESTER PREGNANCY;

ADAPTATION, BIOLOGICAL; ANIMALS; ANTIOXIDANTS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EUTHERIA; MUS;

EID: 60549101306     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2008.12.007     Document Type: Article

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