메뉴 건너뛰기




Volumn 124, Issue 6, 2009, Pages 1483-1489

Spindle assembly checkpoint and p53 deficiencies cooperate for tumorigenesis in mice

Author keywords

Mad2; Madl; P53; Spindle assembly checkpoint; Tumorigenesis

Indexed keywords

PROTEIN MAD1; PROTEIN MAD2; PROTEIN P53; BUB1 SPINDLE CHECKPOINT PROTEIN; CELL CYCLE PROTEIN; MAD2 PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE;

EID: 60549094835     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24094     Document Type: Article
Times cited : (33)

References (46)
  • 2
    • 9244239811 scopus 로고    scopus 로고
    • Gl cell-cycle control and cancer
    • Massague J. Gl cell-cycle control and cancer. Nature 2004;432:298-306.
    • (2004) Nature , vol.432 , pp. 298-306
    • Massague, J.1
  • 3
  • 4
    • 14644398628 scopus 로고    scopus 로고
    • Chromosome instability in neoplasia: Chaotic roots to continuous growth
    • Gagos S, Irminger-Finger I. Chromosome instability in neoplasia: chaotic roots to continuous growth. Int J Biochem Cell Biol 2005;37:1014-33.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 1014-1033
    • Gagos, S.1    Irminger-Finger, I.2
  • 5
    • 9244263076 scopus 로고    scopus 로고
    • Aneuploidy and cancer
    • Rajagopalan H, Lengauer C. Aneuploidy and cancer. Nature 2004;432:338-41.
    • (2004) Nature , vol.432 , pp. 338-341
    • Rajagopalan, H.1    Lengauer, C.2
  • 7
    • 0032800449 scopus 로고    scopus 로고
    • Polypoid dysplasia in Barrett's esophagus: A clinicopathologic, immunohistochemical, and molecular study of five cases
    • Thurberg BL, Duray PH, Odze RD. Polypoid dysplasia in Barrett's esophagus: a clinicopathologic, immunohistochemical, and molecular study of five cases. Hum Pathol 1999;30:745-52.
    • (1999) Hum Pathol , vol.30 , pp. 745-752
    • Thurberg, B.L.1    Duray, P.H.2    Odze, R.D.3
  • 9
    • 10944254814 scopus 로고    scopus 로고
    • The evolutionary origin of genetic instability in cancer development
    • Breivik J. The evolutionary origin of genetic instability in cancer development. Semin Cancer Biol 2005;15:51-60.
    • (2005) Semin Cancer Biol , vol.15 , pp. 51-60
    • Breivik, J.1
  • 10
    • 10944262340 scopus 로고    scopus 로고
    • Mechanisms leading to chromosomal instability
    • Gollin SM. Mechanisms leading to chromosomal instability. Semin Cancer Biol 2005;15:33-42.
    • (2005) Semin Cancer Biol , vol.15 , pp. 33-42
    • Gollin, S.M.1
  • 11
    • 25844475838 scopus 로고    scopus 로고
    • On the road to cancer: Aneuploidy and the mitotic checkpoint
    • Kops GJ, Weaver BA, Cleveland DW. On the road to cancer: aneuploidy and the mitotic checkpoint. Nat Rev Cancer 2005;5:773-85.
    • (2005) Nat Rev Cancer , vol.5 , pp. 773-785
    • Kops, G.J.1    Weaver, B.A.2    Cleveland, D.W.3
  • 12
    • 0037459109 scopus 로고    scopus 로고
    • Centromeres and kinetochores: From epigenetics to mitotic checkpoint signaling
    • Cleveland DW, Mao Y, Sullivan KF. Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell 2003:112: 407-21.
    • (2003) Cell , vol.112 , pp. 407-421
    • Cleveland, D.W.1    Mao, Y.2    Sullivan, K.F.3
  • 13
    • 0037178722 scopus 로고    scopus 로고
    • Maintenance of genome stability in Saccharomyc.es cerevisiae
    • Kolodner RD, Putnam CD, Myung K. Maintenance of genome stability in Saccharomyc.es cerevisiae. Science 2002;297:552-7.
    • (2002) Science , vol.297 , pp. 552-557
    • Kolodner, R.D.1    Putnam, C.D.2    Myung, K.3
  • 14
    • 0025137506 scopus 로고
    • Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae
    • Spencer F, Gerring SL, Connelly C, Hieter P. Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae. Genetics 1990:124:237-49.
    • (1990) Genetics , vol.124 , pp. 237-249
    • Spencer, F.1    Gerring, S.L.2    Connelly, C.3    Hieter, P.4
  • 15
    • 27544434899 scopus 로고    scopus 로고
    • The kinetochore and cancer: What's the connection?
    • Yuen KW, Montpetit B, Hieter P. The kinetochore and cancer: what's the connection? Curr Opin Cell Biol 2005;17:576-82.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 576-582
    • Yuen, K.W.1    Montpetit, B.2    Hieter, P.3
  • 16
    • 27544515607 scopus 로고    scopus 로고
    • The mitotic checkpoint in cancer and aging: What have mice taught us?
    • Baker DJ, Chen J, van Deursen JM. The mitotic checkpoint in cancer and aging: what have mice taught us? Curr Opin Cell Biol 2005;17:583-9.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 583-589
    • Baker, D.J.1    Chen, J.2    van Deursen, J.M.3
  • 17
    • 27544434899 scopus 로고    scopus 로고
    • The kinetochore and cancer: What's the connection?
    • Yuen KW, Montpetit B. Hieter P. The kinetochore and cancer: what's the connection? Curr Opin Cell Biol 2005;17:576-82.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 576-582
    • Yuen, K.W.1    Montpetit, B.2    Hieter, P.3
  • 21
    • 0033614936 scopus 로고    scopus 로고
    • Identification of frequent impairment of the mitotic checkpoint and molecular analysis of the mitotic checkpoint genes. hsMAD2 and p55CDC, in human lung cancers
    • Takahashi T, Haruki N, Nomoto S, Masuda A, Saji S, Osada H, Taka-hashi T. Identification of frequent impairment of the mitotic checkpoint and molecular analysis of the mitotic checkpoint genes. hsMAD2 and p55CDC, in human lung cancers. Oncogene 1999:18:4295-300.
    • (1999) Oncogene , vol.18 , pp. 4295-4300
    • Takahashi, T.1    Haruki, N.2    Nomoto, S.3    Masuda, A.4    Saji, S.5    Osada, H.6    Taka-hashi, T.7
  • 24
    • 0034665634 scopus 로고    scopus 로고
    • Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis
    • Kalitsis P, Earle E, Fowler KJ, Choo KH. Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis. Genes Dev 2000;14:2277-82.
    • (2000) Genes Dev , vol.14 , pp. 2277-2282
    • Kalitsis, P.1    Earle, E.2    Fowler, K.J.3    Choo, K.H.4
  • 25
    • 0035905811 scopus 로고    scopus 로고
    • Michel LS, Liberal V, Chatterjee A. KirchweggerR, Pasche B. Gerald W, Dobles M, Sorger PK, Murty VV, Benezra R. MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells. Nature 2001 ;409:355-9.
    • Michel LS, Liberal V, Chatterjee A. KirchweggerR, Pasche B. Gerald W, Dobles M, Sorger PK, Murty VV, Benezra R. MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells. Nature 2001 ;409:355-9.
  • 28
    • 0037415605 scopus 로고    scopus 로고
    • Rael is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation
    • Babu JR, Jeganathan KB, Baker DJ, Wu X, Kang-Decker N, van Deursen JM. Rael is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation. J Cell Biol 2003;160:341-53.
    • (2003) J Cell Biol , vol.160 , pp. 341-353
    • Babu, J.R.1    Jeganathan, K.B.2    Baker, D.J.3    Wu, X.4    Kang-Decker, N.5    van Deursen, J.M.6
  • 32
    • 23844493744 scopus 로고    scopus 로고
    • Generating chromosome instability through the simultaneous deletion of Mad2 and p53
    • Burds AA, Lutum AS, Sorger PK. Generating chromosome instability through the simultaneous deletion of Mad2 and p53. Proc Natl Acad Sci USA 2005:102:11296-301.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 11296-11301
    • Burds, A.A.1    Lutum, A.S.2    Sorger, P.K.3
  • 35
    • 0026416287 scopus 로고
    • Of pedigrees, probes, and p53: 20 years of family studies
    • Volkers N. Of pedigrees, probes, and p53: 20 years of family studies. J Natl Cancer Inst 1991 ;83:1707-9.
    • (1991) J Natl Cancer Inst , vol.83 , pp. 1707-1709
    • Volkers, N.1
  • 36
    • 34848901685 scopus 로고    scopus 로고
    • The p53 mutation "gradient effect" and its clinical implications
    • Zambetti GP. The p53 mutation "gradient effect" and its clinical implications. J Cell Physiol 2007;213:370-3.
    • (2007) J Cell Physiol , vol.213 , pp. 370-373
    • Zambetti, G.P.1
  • 39
    • 11244341619 scopus 로고    scopus 로고
    • Heterozygosity for p53 (Trp53+/-) accelerates epithelial tumor formation in fanconi anemia complementation group D2 (Fancd2) knockout mice
    • Houghtaling S, Granville L, Akkari Y, Torimaru Y, Olson S, Finegold M, Grompe M. Heterozygosity for p53 (Trp53+/-) accelerates epithelial tumor formation in fanconi anemia complementation group D2 (Fancd2) knockout mice. Cancer Res 2005:65:85-91.
    • (2005) Cancer Res , vol.65 , pp. 85-91
    • Houghtaling, S.1    Granville, L.2    Akkari, Y.3    Torimaru, Y.4    Olson, S.5    Finegold, M.6    Grompe, M.7
  • 40
    • 0034625268 scopus 로고    scopus 로고
    • Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2
    • Dobles M, Liberal V, Scott ML, Benezra R, Sorger PK. Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2. Cell 2000; 101:635-45.
    • (2000) Cell , vol.101 , pp. 635-645
    • Dobles, M.1    Liberal, V.2    Scott, M.L.3    Benezra, R.4    Sorger, P.K.5
  • 41
    • 0037373258 scopus 로고    scopus 로고
    • Gl tetraploidy checkpoint and the suppression of tumorigenesis
    • Margolis RL, Lohez OD, Andreassen PR. Gl tetraploidy checkpoint and the suppression of tumorigenesis. J Cell Biochem 2003;88:673-83.
    • (2003) J Cell Biochem , vol.88 , pp. 673-683
    • Margolis, R.L.1    Lohez, O.D.2    Andreassen, P.R.3
  • 42
    • 0038003943 scopus 로고    scopus 로고
    • p53 deficiency and defective mitotic checkpoint in proliferating T lymphocytes increase chromosomal instability through aberrant exit from mitotic arrest
    • Baek KH, Shin HJ, Yoo JK, Cho JH, Choi YH, Sung YC, McKeon F, Lee CW. p53 deficiency and defective mitotic checkpoint in proliferating T lymphocytes increase chromosomal instability through aberrant exit from mitotic arrest. J Leukoc Biol 2003;73:850-61.
    • (2003) J Leukoc Biol , vol.73 , pp. 850-861
    • Baek, K.H.1    Shin, H.J.2    Yoo, J.K.3    Cho, J.H.4    Choi, Y.H.5    Sung, Y.C.6    McKeon, F.7    Lee, C.W.8
  • 43
    • 0035999976 scopus 로고    scopus 로고
    • Spindle checkpoint requires Madl-bound and Madl-free Mad2
    • Chung E, Chen RH. Spindle checkpoint requires Madl-bound and Madl-free Mad2. Mol Biol Cell 2002;13:1501-11.
    • (2002) Mol Biol Cell , vol.13 , pp. 1501-1511
    • Chung, E.1    Chen, R.H.2
  • 44
    • 0032526415 scopus 로고    scopus 로고
    • Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-proraoting complex, and is involved in regulating anaphase onset and late mitotic events
    • Kallio M, Weinstein J, Daum JR, Burke DJ, Gorbsky GJ. Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-proraoting complex, and is involved in regulating anaphase onset and late mitotic events. J Cell Biol 1998;141:1393-406.
    • (1998) J Cell Biol , vol.141 , pp. 1393-1406
    • Kallio, M.1    Weinstein, J.2    Daum, J.R.3    Burke, D.J.4    Gorbsky, G.J.5
  • 45
    • 36049044125 scopus 로고    scopus 로고
    • The Mad2 conformational dimer: Structure and implications for the spindle assembly checkpoint
    • Mapelli M, Massimiliano L, Santaguida S, Musacchio A. The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint. Cell 2007; 131:730-43.
    • (2007) Cell , vol.131 , pp. 730-743
    • Mapelli, M.1    Massimiliano, L.2    Santaguida, S.3    Musacchio, A.4
  • 46
    • 4344610852 scopus 로고    scopus 로고
    • Timing and checkpoints in the regulation of mitotic progression
    • Meraldi P, Draviam VM, Sorger PK. Timing and checkpoints in the regulation of mitotic progression. Dev Cell 2004:7:45-60.
    • (2004) Dev Cell , vol.7 , pp. 45-60
    • Meraldi, P.1    Draviam, V.M.2    Sorger, P.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.