Identification of frequent impairment of the mitotic checkpoint and molecular analysis of the mitotic checkpoint genes, hsMAD2 and p55CDC, in human lung cancers

Oncogene

Volumn 18, Issue 30, 1999, Pages 4295-4300

  Takahashi, Takao ^a,b   Haruki, Nobuhiro ^a   Nomoto, Shuji ^a   Masuda, Akira ^a   Saji, Shigetoyo ^b   Osada, Hirotaka ^a   Takahashi, Takashi ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

hsMAD2; Lung cancer; Mitotic checkpoint; p55CDC; Pseudogene

Indexed keywords

ARTICLE; CANCER CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENETIC ANALYSIS; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG CANCER; MITOSIS INHIBITION; PATHOGENESIS; PRIORITY JOURNAL; PSEUDOGENE;

ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CALCIUM-BINDING PROTEINS; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SMALL CELL; CARRIER PROTEINS; CELL CYCLE PROTEINS; DNA MUTATIONAL ANALYSIS; FLOW CYTOMETRY; HELA CELLS; HUMANS; LUNG NEOPLASMS; MICROSCOPY, FLUORESCENCE; MITOSIS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NOCODAZOLE; PROTEINS; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, NUCLEIC ACID; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0033614936     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202807     Document Type: Article

References (26)

1. Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP, Sedivy JM, Kinzler KW and Vogelstein B. (1998). Science, 282, 1497-1501.
2. Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JKV, Markowitz SD, Kinzler KW and Vogelstein B. (1998). Nature, 392, 300-303.
3. Chen RH, Waters JC, Salmon ED and Murray AW. (1996). Science, 274, 242-246.
4. Cross SM, Sanchez CA, Morgan CA, Schimke MK, Ramel S, Idzerda RL, Raskind WH and Reid BJ. (1995). Science, 267, 1353-1356.
5. Elledge SJ. (1998). Science, 279, 999-1000.
6. Gotoh K, Yatabe Y, Sugiura T, Takagi K, Ogawa M, Takahashi T, Takahashi T and Mitsudomi T. (1999). Carcinogenesis, (in press)
7. Gualberto A, Aldape K, Kozakiewicz K and Tlsty TD. (1998). Proc. Natl. Acad. Sci. USA, 95, 5166-5171.
8. He X, Patterson TE and Sazer S. (1997). Proc. Natl. Acad. Sci. USA, 94, 7965-7970.
9. Hibi K, Yamakawa K, Ueda R, Horio Y, Murata Y, Tamari M, Uchida K, Takahashi T, Nakamura Y and Takahashi T. (1994). Oncogene, 9, 611-619.
10. Hoyl MA, Totis L and Roberts BT. (1991). Cell, 66, 507-517.
11. Hwang LH, Lau LF, Smith DL, Mistrot CA, Hardwick KG, Hwang ES, Amon A and Murray AW. (1998). Science, 279, 1041-1044.
12. Kim SH, Lin DP, Matsumoto S, Kitazono A and Matsumoto T. (1998). Science, 279, 1045-1047.
13. Kondo M, Suzuki H, Ueda R, Osada H, Takagi K, Takahashi T and Takahashi T. (1995). Oncogene, 10, 1193-1198.
14. Krishnan R, Goodman B, Jin DY, Jeang KT, Collins C, Stetten G and Spencer F. (1998). Genomics, 49, 475-478.
15. Lanni JS and Jacks T. (1998). Mol. Cell. Biol., 18, 1055-1064.
16. Lengauer C, Kinzler KW and Vogelstein B. (1997). Nature, 386, 623-627.
17. Li R and Murray AW. (1991). Cell, 66, 519-531.
18. Li Y and Benezra R. (1996). Science, 274, 246-248.
19. Minna JD, Sekido Y, Fong KM and Gazdar AF. (1997). In: Cancer Principles & Practice of Oncology, 5th edn, vol. 1. De Vita Jr VT, Hellman S and Rosenberg SA (eds). Lippincott-Raven: Philadelphia. pp. 849-857.
20. Paulovich AG, Toczyski DP and Hartwell LH. (1997). Cell, 88, 315-321.
21. Rudner AD and Murray AW. (1996). Curr. Opin. Cell Biol., 8, 773-780.
22. Statistics and Information Department. (1998). In:Vital Statistics of Japan 1996, Vol. 3. Ministry of Health and Welfare: Tokyo. pp. 384-411.
23. Takahashi T, Ueda R, Song X, Nishida K, Shinzato M, Namikawa R, Ariyoshi Y, Ota K, Kato K, Nagatsu T, Imaizumi M, Abe T and Takahashi T. (1986). Cancer Res., 46, 4770-4775.
24. Takahashi T, Nau M, Chiba I, Birrer M, Rosenberg R, Vinocour M, Levitt M, Pass H, Gazdar A and Minna J. (1989). Science, 246, 491-494.
25. Testa JR. (1996). In: Lung Cancer: Principles and Prtictice. Pass HI, Mitchell JB, Johnson DH and Turrisi AT (eds). Lippincott-Raven: Philadelphia. pp. 55-71.
26. Weinstein J, Jacobsen FW, Hsu-Chen J, Wu T and Baum LG. (1994). Mol. Cell. Biol., 14, 3350-3363.