Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons

Molecular and Cellular Neuroscience

Volumn 20, Issue 2, 2002, Pages 323-329

  Ango, Fabrice ^a   Robbe, David ^a   Tu, Jian Cheng ^b   Xiao, Bo ^b   Worley, Paul F ^b   Pin, Jean Philippe ^a   Bockaert, Joël ^a   Fagni, Laurent ^a  

^a CCIPE   (France)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CALCIUM ION; METABOTROPIC RECEPTOR; PROTEIN HOMER1A; PROTEIN HOMER1B; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CALCIUM SIGNALING; CELL CULTURE; CELL SURFACE; CEREBELLUM; CONTROLLED STUDY; GENETIC TRANSFECTION; GRANULE CELL; LATENT PERIOD; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPTIC MEMBRANE;

ANIMALIA;

EID: 0036311506     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.2002.1100     Document Type: Article

References (37)

1. A simple method to transfer plasmid DNA into neuronal primary cultures: Functional expression of the mGlu5 receptor in cerebellar granule cells
2. Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by Homer1 proteins and neuronal excitation
3. Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer
4. Inositol phosphate and cell signalling
5. Homer: A protein that selectively binds metabotropic glutamate receptors
6. The C-terminal domains of the GABA(b) receptor subunits mediate intracellular trafficking but are not required for receptor signaling
7. Modulation of big K+ channel activity by ryanodine receptors and L-type Ca2+ channels in neurons
8. Functional coupling between ryanodine receptors and L-type calcium channels in neurons
9. Coexpression of metabotropic glutamate receptor type 1alpha with Homer-1a/Vesl-1S increases the cell surface expression of the receptor
10. Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1
11. + channel by stimulation of glutamate phosphoinositide-coupled receptors in cultured cerebellar granule cells
12. Complex interactions between mGluRs, intracellular Ca2+ stores and ion channels in neurons
13. Differential subcellular localization of mGluR1a and mGluR5 in the rat and monkey Substantia nigra
14. mGluR1 in cerebellar Purkinje cells essential for long-term depression, synapse elimination, and motor coordination
15. Homer proteins regulate coupling of group I metabotropic glutamate receptors to N-type calcium and M-type potassium channels
16. Vesl, a gene encoding VASP/Ena family related protein, is upregulated during seizure, long-term potentiation and synaptogenesis
17. Activation of metabotropic glutamate receptor 1 accelerates NMDA receptor trafficking
18. Activation of silent synapses by rapid activity-dependent synaptic recruitment of AMPA receptors
19. A trafficking checkpoint controls GABAB receptor heterodimerization
20. RAMPS regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
21. Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism
22. Mutagenesis reveals a role of ABP/GRIP binding to GluR2 in synaptic surface accumulation of the AMPA receptor
23. C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors
24. Molecular properties of inositol 1, 4, 5-trisphosphate receptors
25. Pharmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures
26. Homer1b regulates the trafficking of group I metabotropic glutamate receptors
27. Postsynaptic organization and regulation of excitatory synapses
28. Internalization of ionotropic glutamate receptors in response to mGluR activation
29. Interaction of the N-ethylmaleimide-sensitive factor with AMPA receptors
30. Involvement of unique leucine-zipper motif of PSD-ZIP45 (Homer 1c/vesl-1L) in group 1 metabotropic glutamate receptor clustering
31. Homer binds a novel proline-rich motif and links group I metabotropic glutamate receptorss with IP3 receptors
32. AMPA receptors unbound: Membrane cycling and synaptic plasticity
33. Endogenous amino acid release from cultured cerebellar neuronal cells: Effect of tetanus toxin on glutamate release
34. Heterodimerization is required for the formation of a functional GABAB receptor
35. Cerebellar long-term depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins
36. Homer regulates the association of group I metabotropic glutamate receptors with multivalent complexes of Homer-related, synaptic proteins
37. Homer: A link between neural activity and glutamate receptor function