Synthesis and spectral characterization of a new class of N-(N-methylpiperazinoacetyl)-2,6-diarylpiperidin-4-ones: Antimicrobial, analgesic and antipyretic studies

European Journal of Medicinal Chemistry

Volumn 44, Issue 2, 2009, Pages 577-592

  Aridoss, G ^a   Parthiban, P ^a   Ramachandran, R ^a   Prakash, M ^a   Kabilan, S ^a   Jeong, Yeon Tae ^b  

^a ANNAMALAI UNIVERSITY   (India)

^b Pukyong National University   (South Korea)

Author keywords

Analgesic; Antimicrobial; Antipyretic activities; Conformation; N Methylpiperazine; Piperidin 4 one

Indexed keywords

METHYL GROUP; N (N METHYLPIPERAZINOACETYL) 3 METHYL 2,6 BIS(4 CHLOROPHENYL)PIPERIDIN 4 ONE; N (N METHYLPIPERAZINOACETYL) 3 METHYL 2,6 BIS(4 METHOXYPHENYL)PIPERIDIN 4 ONE; N (N METHYLPIPERAZINOACETYL) 3,5 DIMETHYL 2,6 BIS(4 CHLOROPHENYL)PIPERIDIN 4 ONE; N (N METHYLPIPERAZINOACETYL) 3,5 DIMETHYL 2,6 BIS(4 METHOXYPHENYL)PIPERIDIN 4 ONE; PIPERAZINE DERIVATIVE; PIPERIDONE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIPYRETIC ACTIVITY; ARTICLE; DRUG CONFORMATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; FEVER; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANALGESICS; ANALGESICS, NON-NARCOTIC; ANIMALS; ANTI-INFECTIVE AGENTS; BACTERIA; DRUG EVALUATION, PRECLINICAL; FUNGI; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PAIN; PIPERIDINES; SPECTRUM ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 60149112422     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.03.031     Document Type: Article

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