-
1
-
-
0014547446
-
Escherichia coli K-12 mutants resistant to nalidixic acid: Genetic mapping and dominance studies
-
Hane MW, Wood TH. Escherichia coli K-12 mutants resistant to nalidixic acid: genetic mapping and dominance studies. J Bacteriol 1969; 99: 238-41
-
(1969)
J Bacteriol
, vol.99
, pp. 238-241
-
-
Hane, M.W.1
Wood, T.H.2
-
2
-
-
0023906965
-
Quinolone-resistant mutations of the gyrA gene of Escherichia coli
-
Yoshida H, Kojima T, Yamagishi J, et al. Quinolone-resistant mutations of the gyrA gene of Escherichia coli. Mol Gen Genet 1988; 211: 1-7
-
(1988)
Mol Gen Genet
, vol.211
, pp. 1-7
-
-
Yoshida, H.1
Kojima, T.2
Yamagishi, J.3
-
3
-
-
0024505441
-
gyrA and gyrB mutations in quinolone-resistant strains of Escherichia coli
-
Nakamura S, Nakamura M, Kojima T, et al. gyrA and gyrB mutations in quinolone-resistant strains of Escherichia coli. Antimicrob Agents Chemother 1989; 33: 254-5
-
(1989)
Antimicrob Agents Chemother
, vol.33
, pp. 254-255
-
-
Nakamura, S.1
Nakamura, M.2
Kojima, T.3
-
4
-
-
0025027077
-
New topoisomerase essential for chromosome segregation in E. coli
-
Kato J, Nishimura Y, Imamura R, et al. New topoisomerase essential for chromosome segregation in E. coli. Cell 1990; 63: 393-404
-
(1990)
Cell
, vol.63
, pp. 393-404
-
-
Kato, J.1
Nishimura, Y.2
Imamura, R.3
-
5
-
-
0027939140
-
Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition
-
Hoshino K, Kitamura A, Morrissey I, et al. Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition. Antimicrob Agents Chemother 1994; 38: 2623-7
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 2623-2627
-
-
Hoshino, K.1
Kitamura, A.2
Morrissey, I.3
-
6
-
-
0029043097
-
Analysis of gyrA and grlA mutations in step wise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus
-
Ferrero L, Cameron B, Crouzet J. Analysis of gyrA and grlA mutations in step wise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus. Antimicrob Agents Chemother 1995; 39: 1554-8
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 1554-1558
-
-
Ferrero, L.1
Cameron, B.2
Crouzet, J.3
-
7
-
-
0027956736
-
Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: A primary target of fluoroquinolones
-
Ferrero L, Cameron B, Manse B, et al. Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: a primary target of fluoroquinolones. Mol Microbiol 1994; 13: 641-53
-
(1994)
Mol Microbiol
, vol.13
, pp. 641-653
-
-
Ferrero, L.1
Cameron, B.2
Manse, B.3
-
8
-
-
0029824413
-
Quinolone resistance mutations in topoisomerase IV: Relationship of flqA locus and genetic evidence that topoisomerase IV is the primary target and DNA gyrase the secondary target of fluoroquinolones in Staphylococcus aureus
-
Ng EY, Trucksis M, Hooper DC. Quinolone resistance mutations in topoisomerase IV: relationship of flqA locus and genetic evidence that topoisomerase IV is the primary target and DNA gyrase the secondary target of fluoroquinolones in Staphylococcus aureus. Antimicrob Agents Chemother 1996; 40: 1881-8
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 1881-1888
-
-
Ng, E.Y.1
Trucksis, M.2
Hooper, D.C.3
-
10
-
-
0031020730
-
Quinolone resistance locus nfxD of Escherichia coli is a mutant allele of parE gene encoding a subunit of topoisomerase IV
-
Breines DM, Ouabdesselam S, Ng EY, et al. Quinolone resistance locus nfxD of Escherichia coli is a mutant allele of parE gene encoding a subunit of topoisomerase IV. Antimicrob Agents Chemother 1997; 41: 175-9
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 175-179
-
-
Breines, D.M.1
Ouabdesselam, S.2
Ng, E.Y.3
-
11
-
-
0027489494
-
Limitations of plasmid complementation test for determination of quinolone resistance due to changes in the gyrase A protein and identification of conditional quinolone resistance locus
-
Soussy CJ, Wolfson JS, Ng EY, et al. Limitations of plasmid complementation test for determination of quinolone resistance due to changes in the gyrase A protein and identification of conditional quinolone resistance locus. Antimicrob Agents Chemother 1993; 37: 2588-92
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 2588-2592
-
-
Soussy, C.J.1
Wolfson, J.S.2
Ng, E.Y.3
-
12
-
-
0033081949
-
Mechanisms of quinolone resistance
-
Hooper DC. Mechanisms of quinolone resistance. Drug Resistance Updates 1999; 2: 38-55
-
(1999)
Drug Resistance Updates
, vol.2
, pp. 38-55
-
-
Hooper, D.C.1
-
13
-
-
0031982852
-
Mutations in topoisomerase IV and DNA gyrase of Staphylococcus aureus: Novel pleiotropic effects on quinolone and coumarin activity
-
Fournier B, Hooper DC. Mutations in topoisomerase IV and DNA gyrase of Staphylococcus aureus: Novel pleiotropic effects on quinolone and coumarin activity. Antimicrob Agents Chemother 1998; 42: 121-8
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 121-128
-
-
Fournier, B.1
Hooper, D.C.2
-
14
-
-
10544254692
-
Differential behaviors of Staphylococcus aureus and Escherichia coli type II DNA topoisomerases
-
Blanche F, Cameron B, Bernard FX, et al. Differential behaviors of Staphylococcus aureus and Escherichia coli type II DNA topoisomerases. Antimicrob Agents Chemother 1996; 40: 2714-20
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 2714-2720
-
-
Blanche, F.1
Cameron, B.2
Bernard, F.X.3
-
15
-
-
0031046694
-
Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: Selective targeting of gyrase or topoisomerase IV by quinolones
-
Pan XS, Fisher LM. Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: selective targeting of gyrase or topoisomerase IV by quinolones. Antimicrob Agents Chemother 1997; 41: 471-4
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 471-474
-
-
Pan, X.S.1
Fisher, L.M.2
-
16
-
-
0031784975
-
DNA gyrase and topoisomerase IV are dual targets of clinafloxacin action in Streptococcus pneumoniae
-
Pan XS, Fisher LM. DNA gyrase and topoisomerase IV are dual targets of clinafloxacin action in Streptococcus pneumoniae. Antimicrob Agents Chemother 1998; 42: 2810-6
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 2810-2816
-
-
Pan, X.S.1
Fisher, L.M.2
-
17
-
-
0032946666
-
Streptococcus pneumoniae DNA gyrase and topoisomerase IV: Overexpression, purification, and differential inhibition by fluoroquinolones
-
Pan XS, Fisher LM. Streptococcus pneumoniae DNA gyrase and topoisomerase IV: overexpression, purification, and differential inhibition by fluoroquinolones. Antimicrob Agents Chemother 1999; 43: 1129-36
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 1129-1136
-
-
Pan, X.S.1
Fisher, L.M.2
-
18
-
-
0345414745
-
The unique equipotency of sitafloxacin against topoisomerase IV and DNA gyrase from Streptococcus pneumoniae
-
Nov 15-17: Denver, USA
-
Morrissey I, George JT. The unique equipotency of sitafloxacin against topoisomerase IV and DNA gyrase from Streptococcus pneumoniae. Abstract from the 6th International Symposium on New Quinolones; 1998 Nov 15-17: Denver, USA
-
(1998)
Abstract from the 6th International Symposium on New Quinolones
-
-
Morrissey, I.1
George, J.T.2
-
19
-
-
0032508046
-
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
-
Cole ST, Brosch R, Parkhill J, et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 1998; 393: 537-44
-
(1998)
Nature
, vol.393
, pp. 537-544
-
-
Cole, S.T.1
Brosch, R.2
Parkhill, J.3
-
20
-
-
0032540874
-
Complete genome sequence of Treponema pallidum, the syphilis spirochete
-
Fraser CM, Norris SJ, Weinstock GM, et al. Complete genome sequence of Treponema pallidum, the syphilis spirochete. Science 1998; 281: 375-88
-
(1998)
Science
, vol.281
, pp. 375-388
-
-
Fraser, C.M.1
Norris, S.J.2
Weinstock, G.M.3
-
21
-
-
0030835739
-
The complete genome sequence of the gastric pathogen Helicobacter pylori
-
Tomb JF, White O, Kerlavage AR, et al. The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 1997; 388: 539-47
-
(1997)
Nature
, vol.388
, pp. 539-547
-
-
Tomb, J.F.1
White, O.2
Kerlavage, A.R.3
-
22
-
-
0030045003
-
Structure and mechanism of DNA topoisomerase II
-
Berger JM, Gamblin SJ, Harrison SC, et al. Structure and mechanism of DNA topoisomerase II. Nature 1996; 379: 225-32
-
(1996)
Nature
, vol.379
, pp. 225-232
-
-
Berger, J.M.1
Gamblin, S.J.2
Harrison, S.C.3
-
23
-
-
0000301456
-
Crystal structure of the breakage-reunion domain of DNA gyrase
-
Cabral JH, Jackson AP, Smith CV, et al. Crystal structure of the breakage-reunion domain of DNA gyrase. Nature 1997; 388: 903-6
-
(1997)
Nature
, vol.388
, pp. 903-906
-
-
Cabral, J.H.1
Jackson, A.P.2
Smith, C.V.3
-
24
-
-
0028068693
-
Crystallization of inhibitor complexes of an N-terminal 24 kDa fragment of the DNA gyrase B protein
-
Lewis RJ, Singh OM, Smith CV, et al. Crystallization of inhibitor complexes of an N-terminal 24 kDa fragment of the DNA gyrase B protein. J Mol Biol 1994; 241: 128-30
-
(1994)
J Mol Biol
, vol.241
, pp. 128-130
-
-
Lewis, R.J.1
Singh, O.M.2
Smith, C.V.3
-
25
-
-
0032005064
-
Type II DNA topoisomerases
-
Berger JM. Type II DNA topoisomerases. Curr Opin Struct Biol 1998; 8: 26-32
-
(1998)
Curr Opin Struct Biol
, vol.8
, pp. 26-32
-
-
Berger, J.M.1
-
26
-
-
0027524110
-
A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex
-
Willmott CJ, Maxwell A. A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex. Antimicrob Agents Chemother 1993; 37: 126-7
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 126-127
-
-
Willmott, C.J.1
Maxwell, A.2
-
27
-
-
0032947158
-
Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands
-
Fass D, Bogden CE, Berger JM. Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands. Nat Struct Biol 1999; 6: 322-6
-
(1999)
Nat Struct Biol
, vol.6
, pp. 322-326
-
-
Fass, D.1
Bogden, C.E.2
Berger, J.M.3
-
28
-
-
0024533317
-
Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes
-
Shen LL, Kohlbrenner WE, Weigl D, et al. Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes. J Biol Chem 1989; 264: 2973-8
-
(1989)
J Biol Chem
, vol.264
, pp. 2973-2978
-
-
Shen, L.L.1
Kohlbrenner, W.E.2
Weigl, D.3
-
29
-
-
0030962482
-
Mechanism of quinolone action - A drug-induced structural perturbation of the DNA precedes strand cleavage by topoisomerase IV
-
Marians KJ, Hiasa H. Mechanism of quinolone action - a drug-induced structural perturbation of the DNA precedes strand cleavage by topoisomerase IV. J Biol Chem 1997; 272: 9401-9
-
(1997)
J Biol Chem
, vol.272
, pp. 9401-9409
-
-
Marians, K.J.1
Hiasa, H.2
-
30
-
-
0029904283
-
DNA cleavage is not required for the binding of quinolone drugs to the DNA gyrase - DNA complex
-
Critchlow SE, Maxwell A. DNA cleavage is not required for the binding of quinolone drugs to the DNA gyrase - DNA complex. Biochemistry 1996; 35: 7387-93
-
(1996)
Biochemistry
, vol.35
, pp. 7387-7393
-
-
Critchlow, S.E.1
Maxwell, A.2
-
31
-
-
0032575610
-
Conformational changes in DNA gyrase revealed by limited proteolysis
-
Kampranis SC, Maxwell A. Conformational changes in DNA gyrase revealed by limited proteolysis. J Biol Chem 1998; 273: 22606-14
-
(1998)
J Biol Chem
, vol.273
, pp. 22606-22614
-
-
Kampranis, S.C.1
Maxwell, A.2
-
32
-
-
0032575668
-
The DNA gyrase-quinolone complex -ATP hydrolysis and the mechanism of DNA cleavage
-
Kampranis SC, Maxwell A. The DNA gyrase-quinolone complex -ATP hydrolysis and the mechanism of DNA cleavage. J Biol Chem 1998; 273: 22615-26
-
(1998)
J Biol Chem
, vol.273
, pp. 22615-22626
-
-
Kampranis, S.C.1
Maxwell, A.2
-
33
-
-
0030808667
-
The DNA cleavage reaction of DNA gyrase -comparison of stable ternary complexes formed with enoxacin and CcdB protein
-
Scheirer KE, Higgins NP. The DNA cleavage reaction of DNA gyrase -comparison of stable ternary complexes formed with enoxacin and CcdB protein. J Biol Chem 1997; 272: 27202-9
-
(1997)
J Biol Chem
, vol.272
, pp. 27202-27209
-
-
Scheirer, K.E.1
Higgins, N.P.2
-
34
-
-
0032538454
-
The mechanism of inhibition of topoisomerase IV by quinolone antibacterials
-
Khodursky AB, Cozzarelli NR. The mechanism of inhibition of topoisomerase IV by quinolone antibacterials. J Biol Chem 1998; 273: 27668-77
-
(1998)
J Biol Chem
, vol.273
, pp. 27668-27677
-
-
Khodursky, A.B.1
Cozzarelli, N.R.2
-
35
-
-
0029859964
-
DNA strand cleavage is required for replication fork arrest by a frozen topoisomerase-quinolone-DNA ternary complex
-
Hiasa H, Yousef DO, Marians KJ. DNA strand cleavage is required for replication fork arrest by a frozen topoisomerase-quinolone-DNA ternary complex. J Biol Chem 1996; 271: 26424-9
-
(1996)
J Biol Chem
, vol.271
, pp. 26424-26429
-
-
Hiasa, H.1
Yousef, D.O.2
Marians, K.J.3
-
36
-
-
0019119604
-
DNA gyrase on the bacterial chromosome: Possibility of two levels of action
-
Drlica K, Engle EC, Manes SH. DNA gyrase on the bacterial chromosome: possibility of two levels of action. Proc Natl Acad Sci USA 1980; 77: 6879-83
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 6879-6883
-
-
Drlica, K.1
Engle, E.C.2
Manes, S.H.3
-
37
-
-
0342377454
-
Bipolar localization of Bacillus subtilis topoisomerase IV, an enzyme required for chromosome segregation
-
Huang WM, Libbey JL, Van der Hoeven P, et al. Bipolar localization of Bacillus subtilis topoisomerase IV, an enzyme required for chromosome segregation. Proc Natl Acad Sci USA 1998; 95: 4652-7
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 4652-4657
-
-
Huang, W.M.1
Libbey, J.L.2
Van Der Hoeven, P.3
-
38
-
-
0028034698
-
The complex of DNAgyrase and quinolone drugs with DNA forms a barrier to transcription by RNA polymerase
-
Willmott CJ, Critchlow SE, Eperon IC, et al. The complex of DNAgyrase and quinolone drugs with DNA forms a barrier to transcription by RNA polymerase. J Mol Biol 1994; 242: 351-63
-
(1994)
J Mol Biol
, vol.242
, pp. 351-363
-
-
Willmott, C.J.1
Critchlow, S.E.2
Eperon, I.C.3
|