PDGF, bFGF and IGF-I stimulate the proliferation of intervertebral disc cells in vitro via the activation of the ERK and Akt signaling pathways

European Spine Journal

Volumn 16, Issue 11, 2007, Pages 1858-1866

  Pratsinis, Harris ^a   Kletsas, Dimitris ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

Author keywords

Akt; Cell proliferation; ERK; Growth factors; Intervertebral disc

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BASIC FIBROBLAST GROWTH FACTOR; DNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGENIC AGENT; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; SERINE; SOMATOMEDIN C; THREONINE; WORTMANNIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANNULUS FIBROSUS; ARTICLE; CELL CULTURE; CELL PROLIFERATION; COCCYGEAL BONE; CONTROLLED STUDY; DNA SYNTHESIS; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; IN VITRO STUDY; INTERVERTEBRAL DISK; MALE; MITOGENICITY; NONHUMAN; NUCLEUS PULPOSUS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STIMULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CATTLE; CELL PROLIFERATION; DNA; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLAST GROWTH FACTOR 2; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTERVERTEBRAL DISK; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 36148934197     PISSN: 09406719     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00586-007-0408-9     Document Type: Article

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