-
1
-
-
0038497542
-
Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid
-
Watson,J.D. and Crick,F.H. (1953) Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. Nature, 171, 737-738.
-
(1953)
Nature
, vol.171
, pp. 737-738
-
-
Watson, J.D.1
Crick, F.H.2
-
2
-
-
0028675028
-
A DNA enzyme that cleaves RNA
-
Breaker,R.R. and Joyce,G.F. (1994) A DNA enzyme that cleaves RNA. Chem. Biol., 1, 223-229.
-
(1994)
Chem. Biol
, vol.1
, pp. 223-229
-
-
Breaker, R.R.1
Joyce, G.F.2
-
3
-
-
47749107927
-
Deoxyribozymes: Useful DNA catalysts in vitro and in vivo
-
Baum,D.A. and Silverman,S.K. (2008) Deoxyribozymes: Useful DNA catalysts in vitro and in vivo. Cell Mol. Life Sci., 65, 2156-2174.
-
(2008)
Cell Mol. Life Sci
, vol.65
, pp. 2156-2174
-
-
Baum, D.A.1
Silverman, S.K.2
-
4
-
-
27844496157
-
An active enzyme constructed from a 9-amino acid alphabet
-
Walter,K.U., Vamvaca,K. and Hilvert,D. (2005) An active enzyme constructed from a 9-amino acid alphabet. J. Biol. Chem., 280 37742-37746.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 37742-37746
-
-
Walter, K.U.1
Vamvaca, K.2
Hilvert, D.3
-
5
-
-
0037180804
-
A ribozyme composed of only two different nucleotides
-
Reader,J.S. and Joyce,G.F. (2002) A ribozyme composed of only two different nucleotides. Nature, 420, 841-844.
-
(2002)
Nature
, vol.420
, pp. 841-844
-
-
Reader, J.S.1
Joyce, G.F.2
-
6
-
-
0030898510
-
A general purpose RNA-cleaving DNA enzyme
-
Santoro,S.W. and Joyce,G.F. (1997) A general purpose RNA-cleaving DNA enzyme. Proc. Natl Acad. Sci. USA, 94, 4262-4266.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 4262-4266
-
-
Santoro, S.W.1
Joyce, G.F.2
-
7
-
-
3342955521
-
Tracing sequence diversity change of RNA-cleaving deoxyribozymes under increasing selection pressure during in vitro selection
-
Schlosser,K. and Li,Y. (2004) Tracing sequence diversity change of RNA-cleaving deoxyribozymes under increasing selection pressure during in vitro selection. Biochemistry, 43, 9695-9707.
-
(2004)
Biochemistry
, vol.43
, pp. 9695-9707
-
-
Schlosser, K.1
Li, Y.2
-
8
-
-
49249091384
-
In vitro selection of small RNA-cleaving deoxyribozymes that cleave pyrimidine-pyrimidine junctions
-
Schlosser,K., Gu,J., Lam,J.C. and Li,Y. (2008) In vitro selection of small RNA-cleaving deoxyribozymes that cleave pyrimidine-pyrimidine junctions. Nucleic Acids Res., 36, 4768-4777.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4768-4777
-
-
Schlosser, K.1
Gu, J.2
Lam, J.C.3
Li, Y.4
-
9
-
-
0034650291
-
In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme
-
Li,J., Zheng,W., Kwon,A.H. and Lu,Y. (2000) In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme. Nucleic Acids Res., 28, 481-488.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 481-488
-
-
Li, J.1
Zheng, W.2
Kwon, A.H.3
Lu, Y.4
-
10
-
-
0030498356
-
The Ca2+ ion as a cofactor for a novel RNA-cleaving deoxyribozyme
-
Faulhammer,D. and Famulok,M. (1996) The Ca2+ ion as a cofactor for a novel RNA-cleaving deoxyribozyme. Angew Chem. Int. Ed. Engl., 35, 2809-2813.
-
(1996)
Angew Chem. Int. Ed. Engl
, vol.35
, pp. 2809-2813
-
-
Faulhammer, D.1
Famulok, M.2
-
11
-
-
1142281951
-
Dinucleotide junction cleavage versatility of 8-17 deoxyribozyme
-
Cruz,R.P., Withers,J.B. and Li,Y. (2004) Dinucleotide junction cleavage versatility of 8-17 deoxyribozyme. Chem. Biol., 11, 57-67.
-
(2004)
Chem. Biol
, vol.11
, pp. 57-67
-
-
Cruz, R.P.1
Withers, J.B.2
Li, Y.3
-
12
-
-
0034697291
-
Preferential activation of the 8-17 deoxyribozyme by Ca(2+) ions. Evidence for the identity of 8-17 with the catalytic domain of the Mg5 deoxyribozyme
-
Peracchi,A. (2000) Preferential activation of the 8-17 deoxyribozyme by Ca(2+) ions. Evidence for the identity of 8-17 with the catalytic domain of the Mg5 deoxyribozyme. J. Biol. Chem., 275, 11693-11697.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 11693-11697
-
-
Peracchi, A.1
-
13
-
-
41149095145
-
Sequence-function relationships provide new insight into the cleavage site selectivity of the 8-17 RNA-cleaving deoxyribozyme
-
Schlosser,K., Gu,J., Sule,L. and Li,Y. (2008) Sequence-function relationships provide new insight into the cleavage site selectivity of the 8-17 RNA-cleaving deoxyribozyme. Nucleic Acids Res., 36, 1472-1481.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 1472-1481
-
-
Schlosser, K.1
Gu, J.2
Sule, L.3
Li, Y.4
-
14
-
-
0033575087
-
Kinetics for specific base catalysis of RNA degradation by transesterification involving the 2′-hydroxyl group
-
Li,Y. and Breaker,R.R. (1999) Kinetics for specific base catalysis of RNA degradation by transesterification involving the 2′-hydroxyl group. J. Am. Chem. Soc., 121, 5364-5372.
-
(1999)
J. Am. Chem. Soc
, vol.121
, pp. 5364-5372
-
-
Li, Y.1
Breaker, R.R.2
-
15
-
-
24644514250
-
A mutational analysis of the 8-17 deoxyribozyme core
-
Peracchi,A., Bonaccio,M. and Clerici,M. (2005) A mutational analysis of the 8-17 deoxyribozyme core. J. Mol. Biol., 352, 783-794.
-
(2005)
J. Mol. Biol
, vol.352
, pp. 783-794
-
-
Peracchi, A.1
Bonaccio, M.2
Clerici, M.3
-
16
-
-
2342530310
-
Kinetic and thermodynamic characterization of the RNA-cleaving 8-17 deoxyribozyme
-
Bonaccio,M., Credali,A. and Peracchi,A. (2004) Kinetic and thermodynamic characterization of the RNA-cleaving 8-17 deoxyribozyme. Nucleic Acids Res., 32, 916-925.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 916-925
-
-
Bonaccio, M.1
Credali, A.2
Peracchi, A.3
-
17
-
-
33744915032
-
Phosphoester-transfer mechanism of an RNA-cleaving acidic deoxyribozyme revealed by radioactivity tracking and enzymatic digestion
-
Kandadai,S.A., Chiuman,W. and Li,Y. (2006) Phosphoester-transfer mechanism of an RNA-cleaving acidic deoxyribozyme revealed by radioactivity tracking and enzymatic digestion. Chem. Commun., 2359-2361.
-
(2006)
Chem. Commun
, pp. 2359-2361
-
-
Kandadai, S.A.1
Chiuman, W.2
Li, Y.3
-
18
-
-
0037062949
-
The chemical repertoire of natural ribozymes
-
Doudna,J.A. and Cech,T.R. (2002) The chemical repertoire of natural ribozymes. Nature, 418, 222-228.
-
(2002)
Nature
, vol.418
, pp. 222-228
-
-
Doudna, J.A.1
Cech, T.R.2
-
19
-
-
0038131065
-
A lead-dependent DNAzyme with a two-step mechanism
-
Brown,A.K., Li,J., Pavot,C.M. and Lu,Y. (2003) A lead-dependent DNAzyme with a two-step mechanism. Biochemistry, 42, 7152-7161.
-
(2003)
Biochemistry
, vol.42
, pp. 7152-7161
-
-
Brown, A.K.1
Li, J.2
Pavot, C.M.3
Lu, Y.4
-
21
-
-
0032527839
-
Effects of helical structures formed by the binding arms of DNAzymes and their substrates on catalytic activity
-
Ota,N., Warashina,M., Hirano,K., Hatanaka,K. and Taira,K. (1998) Effects of helical structures formed by the binding arms of DNAzymes and their substrates on catalytic activity. Nucleic Acids Res., 26, 3385-3391.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 3385-3391
-
-
Ota, N.1
Warashina, M.2
Hirano, K.3
Hatanaka, K.4
Taira, K.5
-
22
-
-
0032853242
-
In vitro selection of functional nucleic acids
-
Wilson,D.S. and Szostak,J.W. (1999) In vitro selection of functional nucleic acids. Annu. Rev. Biochem., 68, 611-647.
-
(1999)
Annu. Rev. Biochem
, vol.68
, pp. 611-647
-
-
Wilson, D.S.1
Szostak, J.W.2
-
23
-
-
3042732096
-
Directed evolution of nucleic acid enzymes
-
Joyce,G.F. (2004) Directed evolution of nucleic acid enzymes. Annu. Rev. Biochem., 73, 791-836.
-
(2004)
Annu. Rev. Biochem
, vol.73
, pp. 791-836
-
-
Joyce, G.F.1
-
24
-
-
24744435998
-
Diverse evolutionary trajectories characterize a community of RNA-cleaving deoxyribozymes: A case study into the population dynamics of in vitro selection
-
Schlosser,K. and Li,Y. (2005) Diverse evolutionary trajectories characterize a community of RNA-cleaving deoxyribozymes: A case study into the population dynamics of in vitro selection. J. Mol. Evol., 61, 192-206.
-
(2005)
J. Mol. Evol
, vol.61
, pp. 192-206
-
-
Schlosser, K.1
Li, Y.2
-
25
-
-
0033581938
-
A ribozyme that lacks cytidine
-
Rogers,J. and Joyce,G.F. (1999) A ribozyme that lacks cytidine. Nature, 402, 323-325.
-
(1999)
Nature
, vol.402
, pp. 323-325
-
-
Rogers, J.1
Joyce, G.F.2
-
26
-
-
0345304414
-
Why are there four letters in the genetic alphabet?
-
Szathmary,E. (2003) Why are there four letters in the genetic alphabet? Nat. Rev. Genet., 4, 995-1001.
-
(2003)
Nat. Rev. Genet
, vol.4
, pp. 995-1001
-
-
Szathmary, E.1
-
27
-
-
33646823318
-
Characterization of long RNA-cleaving deoxyribozymes with short catalytic cores: The effect of excess sequence elements on the outcome of in vitro selection
-
Schlosser,K., Lam,J.C. and Li,Y. (2006) Characterization of long RNA-cleaving deoxyribozymes with short catalytic cores: The effect of excess sequence elements on the outcome of in vitro selection. Nucleic Acids Res., 34, 2445-2454.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 2445-2454
-
-
Schlosser, K.1
Lam, J.C.2
Li, Y.3
-
28
-
-
48449093216
-
A contact photo-cross-linking investigation of the active site of the 8-17 deoxyribozyme
-
Liu,Y. and Sen,D. (2008) A contact photo-cross-linking investigation of the active site of the 8-17 deoxyribozyme. J. Mol. Biol., 381 845-859.
-
(2008)
J. Mol. Biol
, vol.381
, pp. 845-859
-
-
Liu, Y.1
Sen, D.2
-
29
-
-
0041702195
-
Ribozyme speed limits
-
Emilsson,G.M., Nakamura,S., Roth,A. and Breaker,R.R. (2003) Ribozyme speed limits. RNA, 9, 907-918.
-
(2003)
RNA
, vol.9
, pp. 907-918
-
-
Emilsson, G.M.1
Nakamura, S.2
Roth, A.3
Breaker, R.R.4
-
30
-
-
0041305819
-
A common speed limit for RNA-cleaving ribozymes and deoxyribozymes
-
Breaker,R.R., Emilsson,G.M., Lazarev,D., Nakamura,S., Puskarz,I.J., Roth,A. and Sudarsan,N. (2003) A common speed limit for RNA-cleaving ribozymes and deoxyribozymes. RNA, 9, 949-957.
-
(2003)
RNA
, vol.9
, pp. 949-957
-
-
Breaker, R.R.1
Emilsson, G.M.2
Lazarev, D.3
Nakamura, S.4
Puskarz, I.J.5
Roth, A.6
Sudarsan, N.7
-
31
-
-
0037466388
-
The roads to and from the RNA world
-
Dworkin,J.P., Lazcano,A. and Miller,S.L. (2003) The roads to and from the RNA world. J. Theor. Biol., 222, 127-134.
-
(2003)
J. Theor. Biol
, vol.222
, pp. 127-134
-
-
Dworkin, J.P.1
Lazcano, A.2
Miller, S.L.3
-
32
-
-
36849148382
-
Origin of life: The RNA world
-
Gilbert,W. (1986) Origin of life: The RNA world. Nature, 319 618.
-
(1986)
Nature
, vol.319
, pp. 618
-
-
Gilbert, W.1
-
33
-
-
33745311268
-
Re-creating an RNA world
-
Muller,U.F. (2006) Re-creating an RNA world. Cell Mol. Life Sci., 63, 1278-1293.
-
(2006)
Cell Mol. Life Sci
, vol.63
, pp. 1278-1293
-
-
Muller, U.F.1
|