Cytokines (IL-1β and TNFα) in relation to biochemical and immunological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats

Toxicology

Volumn 116, Issue 1-3, 1997, Pages 9-16

  Fan, Fang ^a   Yan, Binfang ^a   Wood, Gary ^a   Viluksela, Matti ^a   Rozman, Karl K ^a,b  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin; Delayed type hypersensitivity reaction; Dioxin; Interleukin 1; Phosphoenolpyruvate carboxykinase; TCDD; Tumor necrosis factor

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; INTERLEUKIN 1BETA; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; ANTIGEN; IMMUNOGLOBULIN G; INTERLEUKIN 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG TOXICITY; HISTOCHEMISTRY; IMMUNE RESPONSE; IMMUNIZATION; LIVER; MALE; NONHUMAN; NORTHERN BLOTTING; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; DELAYED HYPERSENSITIVITY; DRUG EFFECT; DRUG HYPERSENSITIVITY; GENETICS; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALIA; OVIS ARIES;

ANIMALS; ANTIGENS; BLOTTING, NORTHERN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG HYPERSENSITIVITY; HYPERSENSITIVITY, DELAYED; IMMUNOGLOBULIN G; INTERLEUKIN-1; LIVER; MALE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TETRACHLORODIBENZODIOXIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030614910     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(96)03514-7     Document Type: Article

References (30)

1. Barbu, V. and Dautry, F. (1989) Northern blot normalization with a 28s-rRNA oligonucleotide probe. Nucleic Acids Res. 17, 7115.
2. Beutler, B. and Cerami, A. (1987) Cachectin: more than a tumor necrosis factor. N. Engl. J. Med. 316, 379-385.
3. Beutler, B. and Cerami, A. (1988) Cachectin (tumor necrosis factor): a macrophage hormone governing cellular metabolism and inflammatory response. Endocr. Rev. 9, 57-66.
4. Beutler, B.A., Milsark, I.W. and Cerami, A. (1985) Cachectin/ tumor necrosis factor: production, distribution, and metabolic fate in vivo. J. Immunol. 135, 3972-3977.
5. Billiau, A. and Vanderkerckhove, F. (1991) Cytokines and their interactions with other inflammatory mediators in the pathogenesis of sepsis and septic shock. Eur. J. Clin. Invest. 21, 559-573.
6. Clark, G.C., Taylor, M.J., Tritscher, A.M. and Lucier, G.W. (1991) Tumor necrosis factor involvement in 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated endotoxin hypersensitivity in C57BL/6J mice congenic at the Ah locus. Toxicol. Appl. Pharmacol. 111, 422-431.
7. Dinarello, C.A. (1991) Interleukin-1 and interleukin-1 antagonism. Blood 77, 1627-1652.
8. Fan, F. and Rozman, K.K. (1994) Relationship between acute toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and disturbance of intermediary metabolism in the Long-Evans rat. Arch. Toxicol. 69, 73-78.
9. Fan, F. and Rozman, K.K. (1995) Short- and long-term biochemical effects of TCDD in female Long-Evans rats. Toxicol. Lett. 75, 209-216.
10. Fan, F., Pinson, D.M. and Rozman, K.K. (1995) Immunomodulatory effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) tested by the popliteal lymph node (PLN) assay. Toxicol. Pathol. 23, 513-517.
11. Fan, F., Wierda, D. and Rozman, K.K. (1996) Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on humoral- and cell-mediated immunity in Sprague-Dawley rats. Toxicology 106, 221-228.
12. Gaido, K.W. and Maness, S.C. (1994) Regulation of gene expression and acceleration of differentiation in human keratinocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol. 127, 199-208.
13. Gorski, J.R., Muzi, G., Weber, L.W., Pereira, D.W., Iatropoulos, M.J. and Rozman, K. (1988) Elevated plasma corticosterone levels and histopathology of the adrenals and thymuses in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats. Toxicology 53, 19-32.
14. Hill, M.R., Stith, R.D. and McCallum, R.E. (1986) Interleukin 1: a regulatory role in glucocorticoid-regulated hepatic metabolism. J. Immunol. 137, 858-862.
15. Hill, M. and McCallum, R. (1991) Altered transcriptional regulation of phosphoenolpyruvate carboxykinase in rats following endoxin treatment. J. Clin. Invest. 88, 811-816.
16. Hill, M.R. and McCallum, R.E. (1992) Identification of tumor necrosis factor as a transcriptional regulator of the phosphoenolpyruvate carboxykinase gene following endotoxin treatment of mice. Infect. Immun. 60: 4040-4050.
17. Le, J. and Vilcek, J. (1987) Tumor necrosis factor and interleukin. 1. Cytokines with multiple overlapping biological activities. Lab. Invest. 56, 234-248.
18. Moos, A.B., Baecher-Steppan, L. and Kerkvliet, N.I. (1994) Acute inflammatory response to sheep red blood cells in mice treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin: the role of proinflammatory cytokines, IL-1 and TNF. Toxicol. Appl. Pharmacol. 127, 331-335.
19. Poland, A. and Knutson, J.C. (1982) 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22, 517-554.
20. Shimommura, Y., Shimizu, H., Takahashi, M., Uehara, Y., Negishi, M., Sato, N., Inukai, T., Kobayashi, I. and Kobayashi, S. (1990) Effects of peripheral administration of recombinant human interleukin-1 beta on feeding behavior of the rat. Life Sci. 47, 2185-2192.
21. Stahl, B.U., Kettrup, A. and Rozman, K. (1992) Comparative toxicity of four chlorinated dibenzo-p-dioxins (CDDs) and their mixture. Part I. Acute toxicity and toxic equivalency factors (TEFs). Arch. Toxicol. 66, 471-477.
22. Stahl, B.U., Beer, D.G., Weber, L.W.D. and Rozman, K.K. (1993) Reduction of hepatic phosphoenolpyruvate carboxykinase (PEPCK) activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is due to decreased mRNA levels. Toxicology 79, 81-95.
23. Sutter, T.R., Guzman, K., Dold, K.M. and Greenlee, W.F. (1991) Targets for dioxin: genes for plasminogen activator inhibitor-2 and interleukin-1β. Science 254, 415-418.
24. Taylor, M.J., Lucier, G.W., Mahler, J.F., Thompson, M., Lockhart, A.C. and Clark, G.C. (1992) Inhibition of acute TCDD toxicity by treatment with anti-tumor necrosis factor antibody or dexamethasone. Toxicol. Appl. Pharmacol. 117, 126-132.
25. Viluksela, M., Stahl, B.U. and Rozman, K.K. (1995) Tissue-specific effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the activity of phosphoenolpyruvate carboxykinase (PEPCK) in rats. Toxicol. Appl. Pharmacol. 135, 308-315.
26. Vos, J.G., Kreeftenberg, J.G., Engel, H.W.B., Minderhoud, A. and Vannoorlejansen, L.M. (1978) Studies of 2,3,7,8-tetrachlorodibenzo-p-dioxin induced immune suppression and decreased resistance to infection: endotoxin hypersensitivity, serum zinc concentrations and effect of thymosin treatment. Toxicology 9, 75-86.
27. Weber, L.W.D., Lebofsky, M., Greim, H. and Rozman, K.K. (1991) Key enzymes of gluconeogenesis are dose-dependently reduced in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats. Arch. Toxicol. 65, 119-123.
28. Weber, L.W.D., Lebofsky, M., Stahl, B.U., Kettrup, A. and Rozman, K.K. (1992) Comparative toxicity of four chlorinated dibenzo-p-dioxins (CDDs) and their mixture. Part II. Structure-activity relationship with inhibition of hepatic phosphoenolpyruvate carboxykinase, pyruvate carboxylase and γ-glutamyl transpeptidase activities. Arch. Toxicol. 66, 478-483.
29. Weber, L.W.D., Lebofsky, M., Stahl, B.U., Smith, S. and Rozman, K.K. (1995) Correlation between toxicity and effects on intermediary metabolism in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated male C57BL/6J and DBA/2J mice. Toxicol. Appl. Pharmacol. 131, 155-162.
30. Zuckerman, S.H., Shellhaas, J. and Butler, L.D. (1989) Differential regulation of lipopolysaccharide-induced interleukin 1 and tumor necrosis factor synthesis: effects of endogenous and exogenous glucocorticoids and the role of the pituitary-adrenal axis. Eur. J. Immunol. 19, 301-305.