Extracellular adenosine induces apoptosis in Caco-2 human colonic cancer cells by activating caspase-9/-3 via A2a adenosine receptors

Journal of Gastroenterology

Volumn 44, Issue 1, 2009, Pages 56-65

  Yasuda, Yoshiyuki ^a   Saito, Masaru ^a   Yamamura, Takehira ^a   Yaguchi, Takahiro ^a   Nishizaki, Tomoyuki ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

A2a adenosine receptor; Adenosine; Apoptosis; Caco 2 cell; Gs protein

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3,7 DIMETHYL 1 PROPARGYLXANTHINE; 9 (TETRAHYDRO 2 FURYL)ADENINE; ADENOSINE; ADENOSINE A2 RECEPTOR; CASPASE 3; CASPASE 8; CASPASE 9; FORSKOLIN; LIPOCORTIN 5; PROPIDIUM IODIDE;

APOPTOSIS; ARTICLE; CELL STRAIN CACO 2; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUOROMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 59049095686     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-008-2273-7     Document Type: Article

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