The G q and G 12 families of heterotrimeric G proteins report functional selectivity

Molecular Pharmacology

Volumn 75, Issue 1, 2009, Pages 235-241

  Zhang, Li ^a   Brass, Lawrence F ^a   Manning, David R ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; 8 ISOPROSTAGLANDIN F2 ALPHA; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PINANE THROMBOXANE A2; SULFUR 35; THROMBOXANE A2 RECEPTOR; 8 EPI PROSTAGLANDIN F2ALPHA; 8-EPI-PROSTAGLANDIN F2ALPHA; CALCIUM; DRUG DERIVATIVE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HYDRAZINE DERIVATIVE; LIGAND; PINANE-THROMBOXANE A2; PROSTAGLANDIN F2 ALPHA; THROMBOXANE A2; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; CELL LINE; CELL SHAPE; CONFORMATION; CYTOLOGY; CYTOSOL; DRUG POTENTIATION; IC 50; KIDNEY; METABOLISM; RADIOASSAY; THROMBOCYTE AGGREGATION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; CALCIUM; CELL LINE; CELL SHAPE; CYTOSOL; DINOPROST; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; HYDRAZINES; INHIBITORY CONCENTRATION 50; KIDNEY; LIGANDS; MOLECULAR CONFORMATION; PLATELET AGGREGATION; RADIOLIGAND ASSAY; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; THROMBOXANE A2;

EID: 58849143054     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.108.050906     Document Type: Article

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