Agonist-selective signaling is determined by the receptor location within the membrane domains

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 27, 2008, Pages 9421-9426

  Zheng, Hui ^a   Chu, Ji ^a   Qiu, Yu ^a   Loh, Horace H ^a   Law, Ping Yee ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Lipid raft; Opioid

Indexed keywords

ADENYLATE CYCLASE; BETA CYCLODEXTRIN; ETORPHINE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANOSINE TRIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG BINDING; ENZYME ACTIVITY; GENE DISRUPTION; GENE INTERACTION; GENE SEQUENCE; GENE TRANSLOCATION; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ARRESTINS; BETA-CYCLODEXTRINS; CELL LINE; ETORPHINE; FORSKOLIN; GENE DELETION; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; HUMANS; MALE; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MORPHINE; MUTANT PROTEINS; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, OPIOID, MU; SIGNAL TRANSDUCTION;

EID: 48249144810     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0802253105     Document Type: Article

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