A Comparative study of β-amyloid peptides Aβ1-42 and Aβ25-35 toxicity in organotypic hippocampal slice cultures

Neurochemical Research

Volumn 34, Issue 2, 2009, Pages 295-303

  Frozza, Rudimar Luiz ^a   Horn, Ana Paula ^a   Hoppe, Juliana Bender ^a   Simão, Fabrício ^a   Gerhardt, Daniéli ^a   Comiran, Ricardo Argenta ^a   Salbego, Christianne Gazzana ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Alzheimer's disease; Amyloid peptide; Caspase 3; Organotypic culture

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[25-35]; CASPASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROPIDIUM IODIDE; PROTEIN KINASE B;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HIPPOCAMPUS; MALE; NERVE CELL LESION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

AMYLOID BETA-PROTEIN; ANIMALS; BLOTTING, WESTERN; CASPASE 3; ENZYME ACTIVATION; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RATS;

RATTUS;

EID: 58849097554     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-008-9776-8     Document Type: Article

References (68)

1. C Haass DJ Selkoe 2007 Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide Nat Mol Cell Biol 8 101 112
2. MS Parihar T Hemnani 2004 Alzheimer's disease pathogenesis and therapeutic interventions J Clin Neurosci 11 456 467
3. MP Mattson SL Chan 2003 Neuronal and glial calcium signaling in Alzheimer's disease Cell Calcium 34 385 397
4. DJ Selkoe D Schenk 2003 Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics Ann Rev Pharm Toxic 43 545 584
5. DJ Selkoe 2000 Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid β-protein Ann NY Acad Sci 924 17 25
6. C Haass MG Schlossmancher AY Hung 1992 Amyloid beta-peptide is produced by cultured cells during normal metabolism Nature 359 322 325
7. M Shoji TE Golde J Ghiso 1992 Production of the Alzheimer amyloid beta protein by normal proteolytic processing Science 258 126 129
8. DJ Selkoe 1996 Amyloid beta-protein and genetics of Alzheimer's disease Biol Chem 271 18295 18298
9. DT Loo AC Copani CJ Pike 1993 Apoptosis is induced by β-amyloid in cultured central nervous system neurons Proc Natl Acad Sci 90 7951 7955
10. DJ Selkoe 1999 Translating cell biology into therapeutics advances in Alzheimer's disease Nat Alerts 399 A23 A31
11. DA Bateman A Chakrabartty 2004 Interactions of Alzheimer amyloid peptides with cultured cells and brain tissue, and their biological consequences Biopolymers (Peptide Science) 76 4 14
12. BA Yankner LR Dawes S Fisher 1989 Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease Science 245 417 420
13. J-H Jang Y-J Surh 2005 β-Amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NFκB signaling pathway Free Rad Biol Med 38 1604 1613
14. K Abe H Saito 2000 Amyloid β neurotoxicity not mediated the mitogen-activated protein kinase cascade in cultured rat hippocampal and cortical neurons Neurosci Lett 292 1 4
15. T Kubo S Nishimura Y Kumagae 2002 In vivo conversion of Racemized--Amyloid([D-Ser26]A-1 40) to truncated and toxic fragments ([D-Ser 26]A-25-35/40) and fragment presence in the brains of Alzheimer's patients J Neurosci Res 70 474 483
16. ME Clementi S Marini M Coletta 2005 Aβ(31-35) and Aβ(25-35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: role of the redox state of methionine-35 FEBS Lett 579 2913 2918
17. CJ Pike AJ Walencewicz-Wasserman J Kosmoski 1995 Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity J Neurochem 64 253 265
18. F Misiti B Sampaolese M Pezzotti 2005 Aβ(31-35) peptide induce apoptosis in PC 12 cells: contrast with Aβ(25-35) peptide and examination of underlying mechanisms Neurochem Int 46 575 583
19. Y Kosuge T Sakikubo K Ishige 2006 Comparative study of endoplasmatic reticulum stress-induced neuronal death in rat cultured hippocampal and cerebellar granule neurons Neurochem Int 49 285 293
20. M Nassif J Hoppe K Santin 2007 β-Amyloid peptide toxicity in organotypic hippocampal slice culture involves Akt/PKB, GSK-3β, and PTEN Neurochem Int 50 229 235
21. CW Cotman JH Su 1996 Mechanisms of neuronal death in Alzheimer's disease Brain Pathol 6 493 506
22. FJ Gunn-Moore JM Tavaré 1998 Apoptosis of cerebellar granule cells induced by serum withdrawal, glutamate or β-amyloid, is independent of Jun kinase or p38 mitogen activated protein kinase activation Neurosci Lett 250 53 56
23. B Stein-Behrens K Adams M Yeh 1992 Failure of beta-amyloid protein fragment 25-35 to cause hippocampal damage in the rat Neurobiol Aging 13 577 579
24. AT Malouf 1992 Effect of beta amyloid peptides on neurons in hippocampal slice cultures Neurobiol Aging 13 543 551
25. L Stoppini PA Buchs D Muller 1991 A simple method for organotypic cultures of nervous tissue J Neurosci Method 37 173 182
26. AJ Bruce B Malfroy M Baudry 1996 β-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a syntetic catalytic free radical scavenger Proc Natl Acad Sci 93 2312 2316
27. IE Holopainen 2005 Organotypic hippocampal slice cultures: a model system to study basic cellular and molecular mechanisms of neuronal cell death, neuroprotection, and synaptic plasticity Neurochem Res 30 1521 1528
28. KM Abdel-Hamid M Tymianski 1997 Mechanisms and effects of intra-cellular calcium buffering on neuronal survival in organotypic hippocampal cultures exposed to anoxia/aglicemia or to excitotoxins J Neurosci 17 3538 3553
29. AK Pringle R Angunawela GJC Wilde 1997 Induction of 72 KDa heat-shock protein following sub-lethal oxygen deprivation in organotypic hippocampal slice cultures Neuropathol Appl Neurobiol 23 289 298
30. LM Valentim R Rodnight AB Geyer 2003 Changes in heat shock protein 27 phosphorylation and immunocontent in response to preconditioning to oxygen and glucose deprivation in organotypic hippocampal cultures Neuroscience 118 379 386
31. H Cimarosti LL Zamin R Frozza 2005 Estradiol protects against oxygen and glucose deprivation in rat hippocampal organotypic cultures and activates Akt and inactivates GSK-3β Neurochem Res 30 191 199
32. AP Horn D Gerhardt AB Geyer 2005 Cellular death in hippocampus in response to PI-3K pathway inhibition and oxygen and glucose deprivation Neurochem Res 30 355 361
33. Y Ito M Ito N Takagi 2003 Neurotoxicity induced by amyloid beta-peptides and ibotenic acid in organotypic hippocampal cultures: protection by S-allyl-l-cystine, a garlic compound Brain Res 985 98 107
34. YH Chong YJ Shin EO Lee 2006 ERK1/2 activation mediates Aβ oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures J Biol Chem 281 20315 20325
35. Y-S Han W-H Zheng S Bastianetto 2004 Neuroprotective effects of resveratrol against β-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C Br J Pharm 141 997 1005
36. J Noraberg BW Kristensen J Zimmer 1999 Markers for neuronal degeneration in organotypic slice cultures Brain Res Prot 3 278 290
37. JD Macklis RD Madison 1990 Progressive incorporation of propidium iodide in cultured mouse neurons correlates with declining electrophysiological status: a fluorescence scale of membrane integrity J Neurosci Method 31 43 46
38. GL Peterson 1983 Determination of total protein Meth Enzym 91 95 119
39. A Baskys Y Adamchik 2001 Neuroprotective effects of extracellular glutamate are absent in organotypic cultures treated with the amyloid peptide Aβ(25-35) Brain Res 13 188 194
40. XH Lu RJ Bradley DS Dwyer 2004 Olanzapine produces trophic effects in vitro and stimulates phosphorylation of Akt/PKB, ERK1/2, and the mitogen-activated protein kinase p38 Brain 1011 58 68
41. EM Ribe M Perez B Puig 2004 Signal transduction during amyloid-beta-peptide neurotoxicity: role in Alzheimer disease Brain Res Rev 47 275 289
42. WW Smith M Gorospe JW Kusiak 2006 Signaling mechanisms underlying a beta toxicity: potential therapeutic targets for Alzheimer's disease CNS Neurol Disord Drug Targets 5 355 361
43. AY Hsia E Masliah L McConlogue 1999 Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models Proc Natl Acad Sci USA 96 3228 3233
44. WL Klein GA Krafft CE Finch 2001 Targeting small Aβ oligomers: the solution to an Alzheimer's disease conundrum? Trends Neurosci 24 219 224
45. FM LaFerla KN Green S Oddo 2007 Intracellular amyloid-β in Alzheimer's disease Nat Neurosci 8 499 509
46. Selkoe DJ (2008) Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior. Behav Brain Res. doi: 10.1016/j.bbr.2008.02. 016
47. DM Walsh I Klyubin JV Fadeeva 2002 Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo Natum potentiation in vivo Nature 416 535 539
48. J Sáez-Valero M de Ceballos DH Small 2002 Changes in molecular isoform distribuition of acetylcholinesterase in rat cortex and cerebrospinal fluid after intracerebroventricular administration of amyloid β-peptide Neurosci Lett 325 199 202
49. MY Stepanichev IM Zdobnova II Zarubenko 2006 Studies of the effects of central administration of β-amyloid peptide (25-35): phatomorphological changes in the hippocampal and impairment of spatial memory Neurosci Behav Physiol 36 101 106
50. S Johansson A-C Radesäter RF Cowburn 2006 Modelling of amyloid β-peptide induced lesions using roller-drum incubation of hippocampal slice cultures from neonatal rats Exp Brain Res 168 11 24
51. T Imai Y Kosuge K Ishige 2007 Amyloid β-protein potentiates Tunicamycin-induced neuronal death in organotypic hippocampal slice cultures Neuroscience 147 639 651
52. K Ishige N Takagi T Imai 2007 Role of caspase-12 in amyloid β-peptide-induced toxicity in organotypic hippocampal slices cultured for long periods J Pharmacol Sci 104 46 55
53. X Song B Wu T Takata 2005 Neuroprotective effect of d-fructose-1,6- bisphosphate against β-amyloid induced neurotoxicity in rat hippocampal organotypic slice culture: involvement of PLC and MEK/ERK signaling pathways Kobe J Med Sci 51 73 83
54. Suh EC, Jung YJ, Kim YA et al (2008) Aβ25-35 induces presynaptic changes in organotypic hippocampal slice cultures. Neurotoxicology. doi: 101016/j.neuro.2008.04.001
55. JN Lee GJ Zipfel DW Choi 1999 The changing landscape of ischemic brain injury mechanisms Nature 399 A7 A14
56. L Papucci L Formigli N Schiavone 2004 Apoptosis shifts to necrosis via intermediate types of cell death by a mechanism depending on c-myc and bcl-2 expression Cell Tissue Res 316 197 209
57. CM Troy SA Rabacchi WJ Friedman 2000 Caspase-2 mediates neuronal cell death induced by β-amyloid J Neuroscience 20 1386 1392
58. C Stadelmann TL Deckwerth A Srinivasan 1999 Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death Am J Pathol 155 1459 1466
59. Y Jin E Yan Y Fan 2005 Sodium ferulate prevents amyloid-beta-induced neurotoxicity through suppression of p38 MAPK and upregulation of ERK-1/2 and Akt/protein kinase B in rat hippocampus Acta Pharm Sin 8 943 951
60. RA Rissman WW Poon M Blurton-Jones 2004 Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology J Clin Invest 14 121 130
61. L Fasulo G Ugolini A Cattaneo 2005 Apoptotic effect of caspase-3 cleaved tau in hippocampal neurons and its potentiation by tau FTDP-mutaion N279K J Alzheimers Dis 7 3 13
62. G Perry H Roder A Nunomura 1999 Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation Neuroreport 10 2411 2415
63. F Plattner M Angelo KP Giese 2006 The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation J Biol Chem 281 25457 25465
64. M Li X Wang MK Meintzer 2000 Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3beta Mol Cell Biol 20 9356 9363
65. F Kerr A Rickle N Nayeem 2006 PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3 FEBS Lett 580 3121 3128
66. D Cook MJ Fry K Hughes 1996 Wingless inactivates glycogen syntase kinase-3 via an intracellular signaling pathway which involves a protein kinase C EMBO J 15 4526 4536
67. NC Inestrosa GV De Ferrari JL Garrido 2002 Wnt signaling involvement in beta-amyloid-dependent neurodegeneration Neurochem Int 41 341 344
68. M Hüll B Muksch RS Akundi 2006 Amyloid beta peptide (25-35) activates protein kinase C leading to cyclooxygenase-2 induction and prostaglandin E2 release in primary midbrain astrocytes Neurochem Int 48 663 672