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Volumn 1, Issue 5, 2002, Pages 305-311

β2-agonist eutomers: A rational option for the treatment of asthma?

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; FENOTEROL; FORMOTEROL; IBUPROFEN; ISOPRENALINE; LEVALBUTEROL; LEVODOPA; LONG ACTING DRUG; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; ROPIVACAINE; SALBUTAMOL; SALBUTAMOL SULFATE; SALMETEROL; TERBUTALINE; ANTIASTHMATIC AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT;

EID: 0042858121     PISSN: 11756365     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03256624     Document Type: Editorial
Times cited : (5)

References (69)
  • 1
    • 0015622044 scopus 로고
    • Some observations on the β-adrenoceptor agonist properties of the isomers of salbutamol
    • Brittain RT, Farmer JB, Marshall RJ. Some observations on the β-adrenoceptor agonist properties of the isomers of salbutamol. Br J Pharmacol 1973; 48: 144-7
    • (1973) Br. J. Pharmacol. , vol.48 , pp. 144-147
    • Brittain, R.T.1    Farmer, J.B.2    Marshall, R.J.3
  • 3
    • 0021262995 scopus 로고
    • Stereochemistry, a basis for sophisticated nonsense in pharmacokinetics and clinical pharmacology
    • Ariëns EJ. Stereochemistry, a basis for sophisticated nonsense in pharmacokinetics and clinical pharmacology. Eur J Clin Pharmacol 1984; 26: 663-8
    • (1984) Eur. J. Clin. Pharmacol. , vol.26 , pp. 663-668
    • Ariëns, E.J.1
  • 4
    • 0014673226 scopus 로고
    • Modification of Parkinsonism: Chronic treatment with L-dopa
    • Cotzias GC, Papavasiliow PS, Gellene R. Modification of Parkinsonism: chronic treatment with L-dopa. N Engl J Med 1969; 280: 337-45
    • (1969) N. Engl. J. Med. , vol.280 , pp. 337-345
    • Cotzias, G.C.1    Papavasiliow, P.S.2    Gellene, R.3
  • 6
    • 0027407851 scopus 로고
    • Stereoisomers and drug toxicity
    • Scott AK. Stereoisomers and drug toxicity. Drug Saf 1993; 8: 149-59
    • (1993) Drug Saf. , vol.8 , pp. 149-159
    • Scott, A.K.1
  • 7
    • 0015130633 scopus 로고
    • Resistance to β-adrenoceptor stimulants (a possible explanation for the rise in asthma deaths)
    • Conolly ME, Davies DS, Dollery CT, et al. Resistance to β-adrenoceptor stimulants (a possible explanation for the rise in asthma deaths). Br J Pharmacol 1971; 43: 389-402
    • (1971) Br. J. Pharmacol. , vol.43 , pp. 389-402
    • Conolly, M.E.1    Davies, D.S.2    Dollery, C.T.3
  • 8
    • 0014408296 scopus 로고
    • Investigation into use of drugs preceding death from asthma
    • Speizer FE, Doll R, Heaf P, et al. Investigation into use of drugs preceding death from asthma. BMJ 1968; 1: 339-43
    • (1968) BMJ , vol.1 , pp. 339-343
    • Speizer, F.E.1    Doll, R.2    Heaf, P.3
  • 9
    • 0018246383 scopus 로고
    • Association between asthma mortality and isoproterenol aerosols: A review
    • Stolley P, Schinnar R. Association between asthma mortality and isoproterenol aerosols: a review. Prev Med 1978; 7: 519-38
    • (1978) Prev. Med. , vol.7 , pp. 519-538
    • Stolley, P.1    Schinnar, R.2
  • 10
    • 0024515162 scopus 로고
    • Prescribed fenoterol and death from asthma in New Zealand, 1981-1983: Case-control study
    • 8644
    • Crane J, Flatt A, Jackson R, et al. Prescribed fenoterol and death from asthma in New Zealand, 1981-1983: case-control study. Lancet 1989; 8644: 917-22
    • (1989) Lancet , pp. 917-922
    • Crane, J.1    Flatt, A.2    Jackson, R.3
  • 11
    • 0025318713 scopus 로고
    • Case control study of prescribed fenoterol and death from asthma in New Zealand, 1977-81
    • Pearce N, Granger J, Atkinson M, et al. Case control study of prescribed fenoterol and death from asthma in New Zealand, 1977-81. Thorax 1990; 45: 170-5
    • (1990) Thorax , vol.45 , pp. 170-175
    • Pearce, N.1    Granger, J.2    Atkinson, M.3
  • 12
    • 0026595475 scopus 로고
    • The use of beta-agonists and the risk of death or near death from asthma
    • Spitzer WO, Suissa S, Ernst P, et al. The use of beta-agonists and the risk of death or near death from asthma. N Engl J Med 1992; 326: 501-6
    • (1992) N. Engl. J. Med. , vol.326 , pp. 501-506
    • Spitzer, W.O.1    Suissa, S.2    Ernst, P.3
  • 13
    • 0028214757 scopus 로고
    • A cohort analysis of excess mortality in asthma and the use of inhaled beta-agonists
    • Suissa S, Ernst P, Boivin JF, et al. A cohort analysis of excess mortality in asthma and the use of inhaled beta-agonists. Am J Respir Crit Care Med 1994; 149: 604-10
    • (1994) Am. J. Respir. Crit. Care Med. , vol.149 , pp. 604-610
    • Suissa, S.1    Ernst, P.2    Boivin, J.F.3
  • 14
    • 0028795433 scopus 로고
    • Inhaled beta-adrenergic receptor agonists in asthma: More harm than good?
    • Barrett TE, Strom BL. Inhaled beta-adrenergic receptor agonists in asthma: more harm than good? Am J Respir Crit Care Med 1995; 151: 574-7
    • (1995) Am. J. Respir. Crit. Care Med. , vol.151 , pp. 574-577
    • Barrett, T.E.1    Strom, B.L.2
  • 15
    • 0028956719 scopus 로고
    • Perspectives in β2-agonist therapy: Vox clamantis in deserto vel lux in tenebris?
    • McFadden ER. Perspectives in β2-agonist therapy: Vox clamantis in deserto vel lux in tenebris? J Allergy Clin Immunol 1995; 9: 641-51
    • (1995) J. Allergy Clin. Immunol. , vol.9 , pp. 641-651
    • McFadden, E.R.1
  • 16
    • 0026723821 scopus 로고
    • Regular beta-agonist therapy: The quality of the evidence
    • [letter]
    • Sears MR, Taylor DR. Regular beta-agonist therapy: the quality of the evidence [letter]. Eur Respir J 1992; 5: 896-7
    • (1992) Eur. Respir. J. , vol.5 , pp. 896-897
    • Sears, M.R.1    Taylor, D.R.2
  • 17
    • 0026441236 scopus 로고
    • A comparison of salmeterol with albuterol in the treatment of mild-to-moderate asthma
    • Pearlman DS, Chervinsky P, LaForce C, et al. A comparison of salmeterol with albuterol in the treatment of mild-to-moderate asthma. N Engl J Med 1992; 327: 1420-5
    • (1992) N. Engl. J. Med. , vol.327 , pp. 1420-1425
    • Pearlman, D.S.1    Chervinsky, P.2    LaForce, C.3
  • 18
    • 15644381143 scopus 로고    scopus 로고
    • Asthma control during long-term treatment with regular inhaled salbutamol and salmeterol
    • Taylor DR, Town GI, Herbison GP, et al. Asthma control during long-term treatment with regular inhaled salbutamol and salmeterol. Thorax 1998; 53: 744-52
    • (1998) Thorax , vol.53 , pp. 744-752
    • Taylor, D.R.1    Town, G.I.2    Herbison, G.P.3
  • 19
    • 1842370350 scopus 로고    scopus 로고
    • Effect of inhaled formoterol and budesonide on exacerbations of asthma
    • Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group
    • Pauwels RA, Lofdahl CG, Postma DS, et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N Engl J Med 1997; 337: 1405-11
    • (1997) N. Engl. J. Med. , vol.337 , pp. 1405-1411
    • Pauwels, R.A.1    Lofdahl, C.G.2    Postma, D.S.3
  • 20
    • 0028824255 scopus 로고
    • Salbutamol in the treatment of asthma
    • [letter]
    • Perrin-Fayolle M. Salbutamol in the treatment of asthma [letter]. Lancet 1995; 346: 1101
    • (1995) Lancet , vol.346 , pp. 1101
    • Perrin-Fayolle, M.1
  • 21
    • 0030090125 scopus 로고    scopus 로고
    • Differential responses of asthmatic airways to enantiomers of albuterol: Implications for clinical treatment of asthma
    • Perrin-Fayolle M, Blum PS, Morley J, et al. Differential responses of asthmatic airways to enantiomers of albuterol: implications for clinical treatment of asthma. Clin Rev Allergy Immunol 1996; 14: 139-47
    • (1996) Clin. Rev. Allergy Immunol. , vol.14 , pp. 139-147
    • Perrin-Fayolle, M.1    Blum, P.S.2    Morley, J.3
  • 22
    • 0030822364 scopus 로고    scopus 로고
    • Effect of single doses of S-salbutamol, R-salbutamol, racemic salbutamol, and placebo on the airway response to methacholine
    • Cockcroft DW, Swystun VA. Effect of single doses of S-salbutamol, R-salbutamol, racemic salbutamol, and placebo on the airway response to methacholine. Thorax 1997; 52: 845-8
    • (1997) Thorax , vol.52 , pp. 845-848
    • Cockcroft, D.W.1    Swystun, V.A.2
  • 23
    • 0035179477 scopus 로고    scopus 로고
    • The therapeutic ratio of R-albuterol is comparable with that of RS-albuterol in asthmatic patients
    • Lötvall J, Palmqvist M, Arvidsson P, et al. The therapeutic ratio of R-albuterol is comparable with that of RS-albuterol in asthmatic patients. J Allergy Clin Immunol 2001; 108: 726-31
    • (2001) J. Allergy Clin. Immunol. , vol.108 , pp. 726-731
    • Lötvall, J.1    Palmqvist, M.2    Arvidsson, P.3
  • 24
    • 0032840560 scopus 로고    scopus 로고
    • Bronchoprotective and bronchodilator effects of single doses of (S)-salbutamol, (R)-salbutamol and racemic salbutamol in patients with bronchial asthma
    • Ramsay CM, Cowan J, Flannery E, et al. Bronchoprotective and bronchodilator effects of single doses of (S)-salbutamol, (R)-salbutamol and racemic salbutamol in patients with bronchial asthma. Eur J Clin Pharmacol 1999; 55: 353-9
    • (1999) Eur. J. Clin. Pharmacol. , vol.55 , pp. 353-359
    • Ramsay, C.M.1    Cowan, J.2    Flannery, E.3
  • 25
    • 0032783997 scopus 로고    scopus 로고
    • Tolerance to the bronchoprotective effect of beta2-agonists: Comparison of the enantiomers of salbutamol with racemic salbutamol and placebo
    • Cockcroft DW, Davis BE, Swystun VA, et al. Tolerance to the bronchoprotective effect of beta2-agonists: comparison of the enantiomers of salbutamol with racemic salbutamol and placebo. J Allergy Clin Immunol 1999; 103: 1049-53
    • (1999) J. Allergy Clin. Immunol. , vol.103 , pp. 1049-1053
    • Cockcroft, D.W.1    Davis, B.E.2    Swystun, V.A.3
  • 26
    • 0025315246 scopus 로고
    • Increased airway reactivity in the guinea-pig follows exposure to intravenous isoprenaline
    • Sanjar S, Kristersson A, Mazzoni L, et al. Increased airway reactivity in the guinea-pig follows exposure to intravenous isoprenaline. J Physiol 1990; 425: 43-54
    • (1990) J. Physiol. , vol.425 , pp. 43-54
    • Sanjar, S.1    Kristersson, A.2    Mazzoni, L.3
  • 27
    • 0001089406 scopus 로고
    • Effects of (+) and racemic salbutamol on airway responses in the guinea-pig
    • Morley J, Chapman ID, Foster A, et al. Effects of (+) and racemic salbutamol on airway responses in the guinea-pig. Br J Pharmacol 1991; 104: 295P
    • (1991) Br. J. Pharmacol. , vol.104
    • Morley, J.1    Chapman, I.D.2    Foster, A.3
  • 28
    • 0005972582 scopus 로고
    • An anomalous effect of salbutamol in sensitised guinea-pigs
    • [abstract]
    • Chapman I, Mazzoni L, Morley J. An anomalous effect of salbutamol in sensitised guinea-pigs [abstract]. Br J Pharmacol 1990; 99: 66P
    • (1990) Br. J. Pharmacol. , vol.99
    • Chapman, I.1    Mazzoni, L.2    Morley, J.3
  • 29
    • 0027536722 scopus 로고
    • Enhancement of airway reactivity to histamine by isoprenaline and related β-adrenoceptor agonists in the guinea-pig
    • Galland BC, Blackman JG. Enhancement of airway reactivity to histamine by isoprenaline and related β-adrenoceptor agonists in the guinea-pig. Br J Pharmacol 1993; 108: 1016-23
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 1016-1023
    • Galland, B.C.1    Blackman, J.G.2
  • 30
    • 0031595676 scopus 로고    scopus 로고
    • Pulmonary neuronal M2 muscarinic receptor function in asthma and animal models of hyperreactivity
    • Costello RW, Jacoby DB, Fryer AD. Pulmonary neuronal M2 muscarinic receptor function in asthma and animal models of hyperreactivity. Thorax 1998; 53: 613-6
    • (1998) Thorax , vol.53 , pp. 613-616
    • Costello, R.W.1    Jacoby, D.B.2    Fryer, A.D.3
  • 31
    • 0026354242 scopus 로고
    • Steric aspects of agonism and antagonism at beta-adrenoceptors: Synthesis of and pharmacological experiments with the enantiomers of formoterol and their diastereomers
    • Trofast J, Osterberg K, Kallstrom BL, et al. Steric aspects of agonism and antagonism at beta-adrenoceptors: synthesis of and pharmacological experiments with the enantiomers of formoterol and their diastereomers. Chirality 1991; 3: 443-50
    • (1991) Chirality , vol.3 , pp. 443-450
    • Trofast, J.1    Osterberg, K.2    Kallstrom, B.L.3
  • 32
    • 0034013676 scopus 로고    scopus 로고
    • The effect of the enantiomers of formoterol on inherent and induced tone in guinea-pig trachea and human bronchus
    • Schmidt D, Kallstrom BL, Waldeck B, et al. The effect of the enantiomers of formoterol on inherent and induced tone in guinea-pig trachea and human bronchus. Naunyn Schmiedebergs Arch Pharmacol 2000; 361: 405-9
    • (2000) Naunyn Schmiedebergs Arch. Pharmacol. , vol.361 , pp. 405-409
    • Schmidt, D.1    Kallstrom, B.L.2    Waldeck, B.3
  • 33
    • 0030090579 scopus 로고    scopus 로고
    • Effects of albuterol enantiomers on in vitro bronchial reactivity
    • Johansson F, Rydberg I, Aberg G, et al. Effects of albuterol enantiomers on in vitro bronchial reactivity. Clin Rev Allergy Immunol 1996; 14: 57-64
    • (1996) Clin. Rev. Allergy Immunol. , vol.14 , pp. 57-64
    • Johansson, F.1    Rydberg, I.2    Aberg, G.3
  • 35
    • 0030482252 scopus 로고    scopus 로고
    • Steric aspects of formoterol and terbutaline: Is there an adverse effect of the distomer on airway smooth muscle function?
    • Kallstrom BL, Sjoberg J, Waldeck B. Steric aspects of formoterol and terbutaline: is there an adverse effect of the distomer on airway smooth muscle function? Chirality 1996; 8: 567-73
    • (1996) Chirality , vol.8 , pp. 567-573
    • Kallstrom, B.L.1    Sjoberg, J.2    Waldeck, B.3
  • 36
    • 0031966248 scopus 로고    scopus 로고
    • (S)-Albuterol increases intracellular free calcium by muscarinic receptor activation and a phospholipase C-dependent mechanism in airway smooth muscle
    • Mitra S, Ugur M, Ugur O, et al. (S)-Albuterol increases intracellular free calcium by muscarinic receptor activation and a phospholipase C-dependent mechanism in airway smooth muscle. Mol Pharmacol 1998; 53: 347-54
    • (1998) Mol. Pharmacol. , vol.53 , pp. 347-354
    • Mitra, S.1    Ugur, M.2    Ugur, O.3
  • 37
    • 0035001863 scopus 로고    scopus 로고
    • (S)-Albuterol increases the production of histamine and IL-4 in mast cells
    • Cho SH, Hartleroad JY, Oh CK. (S)-Albuterol increases the production of histamine and IL-4 in mast cells. Int Arch Allergy Immunol 2001; 124: 478-84
    • (2001) Int. Arch. Allergy Immunol. , vol.124 , pp. 478-484
    • Cho, S.H.1    Hartleroad, J.Y.2    Oh, C.K.3
  • 38
    • 0024424749 scopus 로고
    • Tachyphylaxis to systemic but not to airway responses during prolonged therapy with high dose inhaled salbutamol in asthmatics
    • Lipworth BJ, Struthers AD, McDevitt DG. Tachyphylaxis to systemic but not to airway responses during prolonged therapy with high dose inhaled salbutamol in asthmatics. Am Rev Respir Dis 1989; 140: 586-92
    • (1989) Am. Rev. Respir. Dis. , vol.140 , pp. 586-592
    • Lipworth, B.J.1    Struthers, A.D.2    McDevitt, D.G.3
  • 39
    • 0032843257 scopus 로고    scopus 로고
    • Tolerance to beta-agonists during acute bronchoconstriction
    • Hancox RJ, Aldridge RE, Cowan JO, et al. Tolerance to beta-agonists during acute bronchoconstriction. Eur Respir J 1999; 14: 283-7
    • (1999) Eur. Respir. J. , vol.14 , pp. 283-287
    • Hancox, R.J.1    Aldridge, R.E.2    Cowan, J.O.3
  • 40
    • 0015694542 scopus 로고
    • Relative potency of (-)- and (±)-salbutamol on guinea pig tracheal tissue
    • Hawkins CJ, Klease GT. Relative potency of (-)- and (±)-salbutamol on guinea pig tracheal tissue. J Med Chem 1973; 16: 856-7
    • (1973) J. Med. Chem. , vol.16 , pp. 856-857
    • Hawkins, C.J.1    Klease, G.T.2
  • 41
    • 0015114980 scopus 로고
    • Absolute configuration of the optical isomers of salbutamol
    • Hartley D, Middlemiss D. Absolute configuration of the optical isomers of salbutamol. J Med Chem 1971; 14: 995-6
    • (1971) J. Med. Chem. , vol.14 , pp. 995-996
    • Hartley, D.1    Middlemiss, D.2
  • 42
    • 0033380238 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of cumulative single doses of inhaled salbutamol enantiomers in asthmatic subjects
    • Gumbhir-Shah K, Kellerman DJ, DeGraw S, et al. Pharmacokinetics and pharmacodynamics of cumulative single doses of inhaled salbutamol enantiomers in asthmatic subjects. Pulm Pharmacol Ther 1999; 12: 353-62
    • (1999) Pulm. Pharmacol. Ther. , vol.12 , pp. 353-362
    • Gumbhir-Shah, K.1    Kellerman, D.J.2    DeGraw, S.3
  • 43
    • 0032417246 scopus 로고    scopus 로고
    • Improved bronchodilation with levalbuterol compared with racemic albuterol in patients with asthma
    • Nelson HS, Bensch G, Pleskow WW, et al. Improved bronchodilation with levalbuterol compared with racemic albuterol in patients with asthma. J Allergy Clin Immunol 1998; 102: 943-52
    • (1998) J. Allergy Clin. Immunol. , vol.102 , pp. 943-952
    • Nelson, H.S.1    Bensch, G.2    Pleskow, W.W.3
  • 44
    • 0033056771 scopus 로고    scopus 로고
    • The safety and efficacy of nebulized levalbuterol compared with racemic albuterol and placebo in the treatment of asthma in pediatric patients
    • Gawchik SM, Saccar CL, Noonan M, et al. The safety and efficacy of nebulized levalbuterol compared with racemic albuterol and placebo in the treatment of asthma in pediatric patients. J Allergy Clin Immunol 1999; 103: 615-21
    • (1999) J. Allergy Clin. Immunol. , vol.103 , pp. 615-621
    • Gawchik, S.M.1    Saccar, C.L.2    Noonan, M.3
  • 45
    • 0033944910 scopus 로고    scopus 로고
    • Dose-response evaluation of levalbuterol versus racemic albuterol in patients with asthma
    • Handley DA, Tinkelman D, Noonan M, et al. Dose-response evaluation of levalbuterol versus racemic albuterol in patients with asthma. J Asthma 2000; 37: 319-27
    • (2000) J. Asthma , vol.37 , pp. 319-327
    • Handley, D.A.1    Tinkelman, D.2    Noonan, M.3
  • 46
    • 0005980933 scopus 로고    scopus 로고
    • Levosalbutamol
    • Black P. Levosalbutamol. Biodrugs 1999; 11: 439-40
    • (1999) Biodrugs , vol.11 , pp. 439-440
    • Black, P.1
  • 47
    • 0035191611 scopus 로고    scopus 로고
    • Levalbuterol and racemic albuterol: Are there therapeutic differences?
    • Ahrens R, Weinberger M. Levalbuterol and racemic albuterol: are there therapeutic differences? J Allergy Clin Immunol 2001; 108: 681-4
    • (2001) J. Allergy Clin. Immunol. , vol.108 , pp. 681-684
    • Ahrens, R.1    Weinberger, M.2
  • 48
    • 4243579052 scopus 로고    scopus 로고
    • Lower doses of Xenoprex are as effective as racemic albuterol in the prevention of exercise-induced asthma (EIB)
    • [abstract]
    • Busse WW, Greos L, Vaickus L. Lower doses of Xenoprex are as effective as racemic albuterol in the prevention of exercise-induced asthma (EIB) [abstract]. J Allergy Clin Immunol 1999; 103: S136
    • (1999) J. Allergy Clin. Immunol. , vol.103
    • Busse, W.W.1    Greos, L.2    Vaickus, L.3
  • 49
    • 85006955020 scopus 로고    scopus 로고
    • Levalbuterol is effective in the prevention of cold air induced bronchospasm and does not induce tachyphylaxis in the degree of bronchoprotection
    • [abstract]
    • Israel E, Hong C, Claus R, et al. Levalbuterol is effective in the prevention of cold air induced bronchospasm and does not induce tachyphylaxis in the degree of bronchoprotection [abstract]. J Allergy Clin Immunol 2000; 105: S22
    • (2000) J. Allergy Clin. Immunol. , vol.105
    • Israel, E.1    Hong, C.2    Claus, R.3
  • 50
    • 0030819181 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of single oral doses of albuterol and its enantiomers in humans
    • Boulton DW, Fawcett JP. Pharmacokinetics and pharmacodynamics of single oral doses of albuterol and its enantiomers in humans. Clin Pharmacol Ther 1997; 62: 138-44
    • (1997) Clin. Pharmacol. Ther. , vol.62 , pp. 138-144
    • Boulton, D.W.1    Fawcett, J.P.2
  • 51
    • 0024532544 scopus 로고
    • Pharmacokinetic evaluation in man of terbutaline given as separate enantiomers and as the racemate
    • Borgström L, Nyberg L, Jonsson S, et al. Pharmacokinetic evaluation in man of terbutaline given as separate enantiomers and as the racemate. Br J Clin Pharmacol 1989; 27: 49-56
    • (1989) Br. J. Clin. Pharmacol. , vol.27 , pp. 49-56
    • Borgström, L.1    Nyberg, L.2    Jonsson, S.3
  • 52
    • 0025285660 scopus 로고
    • Relative duodenal absorption of the two enantiomers of terbutaline after duodenal administration
    • Borgström L, Kennedy BM, Nilsson B, et al. Relative duodenal absorption of the two enantiomers of terbutaline after duodenal administration. Eur J Clin Pharmacol 1990; 38: 621-3
    • (1990) Eur. J. Clin. Pharmacol. , vol.38 , pp. 621-623
    • Borgström, L.1    Kennedy, B.M.2    Nilsson, B.3
  • 53
  • 54
    • 0005939098 scopus 로고    scopus 로고
    • Enantioselective disposition of β2-agonists in humans
    • Costello JF, editor. Carnforth: The Parthenon Publishing Group Inc
    • Fawcett JP, Boulton DW. Enantioselective disposition of β2-agonists in humans. In: Costello JF, editor. Sympathomimetic enantiomers in the treatment of asthma. Carnforth: The Parthenon Publishing Group Inc, 1997: 101-122
    • (1997) Sympathomimetic Enantiomers in the Treatment of Asthma , pp. 101-122
    • Fawcett, J.P.1    Boulton, D.W.2
  • 55
    • 0032429693 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamic characteristics and safety of inhaled albuterol enantiomers in healthy volunteers
    • Gumbhir-Shah K, Kellerman DJ, DeGraw S, et al. Pharmacokinetics and pharmacodynamic characteristics and safety of inhaled albuterol enantiomers in healthy volunteers. J Clin Pharmacol 1998; 38: 1096-106
    • (1998) J. Clin. Pharmacol. , vol.38 , pp. 1096-1106
    • Gumbhir-Shah, K.1    Kellerman, D.J.2    DeGraw, S.3
  • 56
    • 0033006646 scopus 로고    scopus 로고
    • Pharmacokinetics and tolerability of formoterol in healthy volunteers after a single high dose of Foradil dry powder inhalation via aerolizer
    • Lecaillon JB, Kaiser G, Palmisano M, et al. Pharmacokinetics and tolerability of formoterol in healthy volunteers after a single high dose of Foradil dry powder inhalation via aerolizer. Eur J Clin Pharmacol 1999; 55: 131-8
    • (1999) Eur. J. Clin. Pharmacol. , vol.55 , pp. 131-138
    • Lecaillon, J.B.1    Kaiser, G.2    Palmisano, M.3
  • 57
    • 0035115284 scopus 로고    scopus 로고
    • The pharmacokinetics of levosalbutamol: What are the clinical implications?
    • Boulton DW, Fawcett JP. The pharmacokinetics of levosalbutamol: what are the clinical implications? Clin Pharmacokinet 2001; 40: 23-40
    • (2001) Clin. Pharmacokinet. , vol.40 , pp. 23-40
    • Boulton, D.W.1    Fawcett, J.P.2
  • 58
    • 0033956072 scopus 로고    scopus 로고
    • Enantiomeric disposition of inhaled, intravenous and oral racemic-salbutamol in man: No evidence of enantioselective lung metabolism
    • Ward JK, Dow J, Dallow N, et al. Enantiomeric disposition of inhaled, intravenous and oral racemic-salbutamol in man: no evidence of enantioselective lung metabolism. Br J Clin Pharmacol 2000; 49: 15-22
    • (2000) Br. J. Clin. Pharmacol. , vol.49 , pp. 15-22
    • Ward, J.K.1    Dow, J.2    Dallow, N.3
  • 59
    • 0025284391 scopus 로고
    • Stereoselective sulphate conjugation of racemic terbutaline by human liver cytosol
    • Walle T, Walle UK. Stereoselective sulphate conjugation of racemic terbutaline by human liver cytosol. Br J Clin Pharmacol 1990; 30: 127-33
    • (1990) Br. J. Clin. Pharmacol. , vol.30 , pp. 127-133
    • Walle, T.1    Walle, U.K.2
  • 60
    • 0026520917 scopus 로고
    • Stereoselective sulphate conjugation of 4-hydroxypropranolol and terbutaline by the human liver phenolsulfotransferases
    • Walle T, Walle UK. Stereoselective sulphate conjugation of 4-hydroxypropranolol and terbutaline by the human liver phenolsulfotransferases. Drug Metab Dispos 1992; 20: 333-6
    • (1992) Drug Metab. Dispos. , vol.20 , pp. 333-336
    • Walle, T.1    Walle, U.K.2
  • 61
    • 0033955814 scopus 로고    scopus 로고
    • Stereoselective glucuronidation of formoterol by human liver microsomes
    • Zhang M, Fawcett JP, Kennedy JM, et al. Stereoselective glucuronidation of formoterol by human liver microsomes. Br J Clin Pharmacol 2000; 49: 152-7
    • (2000) Br. J. Clin. Pharmacol. , vol.49 , pp. 152-157
    • Zhang, M.1    Fawcett, J.P.2    Kennedy, J.M.3
  • 62
    • 0030001818 scopus 로고    scopus 로고
    • Determination by HPLC with electrochemical detection of formoterol RR and SS enantiomers in urine
    • Butter JJ, van den Berg BTJ, Portier EJG, et al. Determination by HPLC with electrochemical detection of formoterol RR and SS enantiomers in urine. J Liquid Chromatogr Rel Tech 1996; 19: 993-1005
    • (1996) J. Liquid Chromatogr. Rel. Tech. , vol.19 , pp. 993-1005
    • Butter, J.J.1    van den Berg, B.T.J.2    Portier, E.J.G.3
  • 63
    • 0033029494 scopus 로고    scopus 로고
    • Rapid chiral high-performance liquid chromatographic assay for salmeterol and alpha-hydroxysalmeterol: Application to in vitro metabolism studies
    • Zhang M, Fawcett JP, Shaw JP. Rapid chiral high-performance liquid chromatographic assay for salmeterol and alpha-hydroxysalmeterol: application to in vitro metabolism studies. J Chromatogr B Biomed Sci Appl 1999; 729: 225-30
    • (1999) J. Chromatogr. B Biomed. Sci. Appl. , vol.729 , pp. 225-230
    • Zhang, M.1    Fawcett, J.P.2    Shaw, J.P.3
  • 64
    • 0028881704 scopus 로고
    • Determination of salbutamol enantiomers in human plasma and urine by chiral high-performance liquid chromatography
    • Boulton DW, Fawcett JP. Determination of salbutamol enantiomers in human plasma and urine by chiral high-performance liquid chromatography. J Chromatogr B Biomed Appl 1995; 672: 103-9
    • (1995) J. Chromatogr. B Biomed. Appl. , vol.672 , pp. 103-109
    • Boulton, D.W.1    Fawcett, J.P.2
  • 65
    • 0030044446 scopus 로고    scopus 로고
    • Enantioselective disposition of salbutamol in man following oral and intravenous administration
    • Boulton DW, Fawcett JP. Enantioselective disposition of salbutamol in man following oral and intravenous administration. Br J Clin Pharmacol 1996; 41: 35-40
    • (1996) Br. J. Clin. Pharmacol. , vol.41 , pp. 35-40
    • Boulton, D.W.1    Fawcett, J.P.2
  • 66
    • 0036378220 scopus 로고    scopus 로고
    • Stereoselective urinary excretion of formoterol and its glucuronide conjugate in human
    • In press
    • Zhang M, Fawcett JP, Shaw JP. Stereoselective urinary excretion of formoterol and its glucuronide conjugate in human. Br J Clin Pharmacol. In press
    • Br. J. Clin. Pharmacol.
    • Zhang, M.1    Fawcett, J.P.2    Shaw, J.P.3
  • 67
    • 0035036188 scopus 로고    scopus 로고
    • Pharmacology of chiral compounds: 2-arylpropionic acid derivatives
    • Landoni MF, Soraci A. Pharmacology of chiral compounds: 2-arylpropionic acid derivatives. Curr Drug Metab 2001; 2: 37-51
    • (2001) Curr. Drug Metab. , vol.2 , pp. 37-51
    • Landoni, M.F.1    Soraci, A.2
  • 68
    • 0004192250 scopus 로고
    • 5th ed. New York: John Wiley and Sons Inc
    • Solomons TWG. Organic chemistry. 5th ed. New York: John Wiley and Sons Inc., 1992: 231-2
    • (1992) Organic Chemistry , pp. 231-232
    • Solomons, T.W.G.1
  • 69
    • 0032588050 scopus 로고    scopus 로고
    • Beta2-agonist enantiomers: Is there a glitch with the chiral switch?
    • Fawcett JP, Taylor DR. Beta2-agonist enantiomers: is there a glitch with the chiral switch? Eur Respir J 1999; 13: 1223-4
    • (1999) Eur. Respir. J. , vol.13 , pp. 1223-1224
    • Fawcett, J.P.1    Taylor, D.R.2


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