Aberrant promotor methylation in MDS hematopoietic cells during in vitro lineage specific differentiation is differently associated with DNMT isoforms

Leukemia Research

Volumn 33, Issue 3, 2009, Pages 434-442

  Hopfer, Olaf ^a   Komor, Martina ^b   Koehler, Ina Sabine ^a   Freitag, Claudia ^a   Schulze, Matthias ^c   Hoelzer, Dieter ^b   Thiel, Eckhard ^a   Hofmann, Wolf Karsten ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

Author keywords

DNMT; Erythropoiesis; Hematopoietic stem cells; MDS; Methylation; Thrombopoiesis

Indexed keywords

DEATH ASSOCIATED PROTEIN KINASE; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; GENOMIC DNA; PROTEIN P15; PROTEIN P16; PROTEIN P73; SURVIVIN;

APOPTOSIS; ARTICLE; CD34 SELECTION; CELL DIFFERENTIATION; CELL LINEAGE; DNA METHYLATION; DNA REPAIR; ERYTHROPOIESIS; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; HUMAN; IN VITRO STUDY; MYELODYSPLASTIC SYNDROME; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; THROMBOCYTOPOIESIS;

APOPTOSIS; CASE-CONTROL STUDIES; CELL CYCLE; CELL DIFFERENTIATION; CELLS, CULTURED; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA REPAIR; ERYTHROPOIESIS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; MYELODYSPLASTIC SYNDROMES; PROMOTER REGIONS, GENETIC; PROTEIN ISOFORMS;

EID: 58749099275     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2008.08.014     Document Type: Article

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