Antimicrobial activity of lysozyme with special relevance to milk

African Journal of Biotechnology

Volumn 7, Issue 25, 2008, Pages 4856-4867

  Benkerroum, Noreddine ^a  

^a INSTITUT AGRONOMIQUE ET VÉTÉRINAIRE HASSAN II   (Morocco)

Author keywords

Antimicrobial activity; Lysozyme; Mechanism of action; Milk; Resistance

Indexed keywords

LIPOPOLYSACCHARIDE; LYSOZYME; PEPTIDOGLYCAN;

ANTIMICROBIAL ACTIVITY; DEACETYLATION; ENTAMOEBA HISTOLYTICA; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; MILK; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHAGOCYTOSIS; PSEUDOMONAS AERUGINOSA; REVIEW; SALMONELLA ENTERICA; SENSITIVITY ANALYSIS;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 58649122671     PISSN: None     EISSN: 16845315     Source Type: Journal    
DOI: None     Document Type: Review

References (120)

1. Abergel C, Monchois V, Byrne D, Chenivesse S, Lembo F, Lazzaroni JC, Claverie JM (2007). Structure and evolution of the Ivy protein family, unexpected lysozyme inhibitors in Gram-negative bacteria. Proc. Nat. Acad. Sci. (USA). 104: 6394-6399.
2. Wagstrom AE, Yoon KJ, Zimmerman JJ (2000). Immune components in porcine mammary secretions. Viral Immunol. 13: 383-397.
3. Alsteens D, Dupres V, McEvoy K, Wildling L, Gruber HJ, Dufrene YF (2008). Structure, cell wall elasticity and polysaccharide properties of living yeast cells, as probed by AFM. Nanotechnology. 19: 384005 (9pp) doi:10.1088/0957-4484/ 19/38/384005 (Open access).
4. Araki T, Nakatani T, Nakayama K, Ito E (1972). Occurrence of IV-Nonsubstituted Glucosamine Residues in Peptidoglycan of Lysozyme-resistant Cell Walls from Bacillus cereus. J. Biol. Chem. 247: 6312-6322.
5. Bachali S, Bailly X, Jolles J, Jolles P, Deutsch JS (2004). The lysozyme of the starfish Asterias rubens. A paradygmatic type I lysozyme. Eur.J. Biochem. 271: 237-242.
6. Barbour EK, Nabbut NH, Frerisch WM, Al-Nakhli HM (1984). Inhibition of pathogenic bacteria by camel's milk: relation to whey lysozyme and stage of lactation. J. Food Prot. 47: 838-840.
7. Bera A, Biswas R, Herbert S, Kulauzovic E, Weidenmaier C, Peschel A, Götz F (2007). Influence of Wall Teichoic Acid on Lysozyme Resistance in Staphylococcus aureus. J. Bact. 189: 280-283.
8. Bera A, Herbert S, Jakob A, Vollmer W, Gotz F (2005). Why are pathogenic staphylococci so lysozyme resistant? The peptidoglycan O-acetyltransferase OatA is the major determinant for lysozyme resistance of Staphylococcus aureus. Mol. Microbiol. 55: 778-787.
9. Bera A, Biswas R, Herbert S, Gotz F (2006). The presence of peptidoglycan O-acetyltransferase in various staphylococcal species correlates with Lysozyme resistance and pathogenicity. Inf. immunol. 74: 4598-4604
10. Blanc B (1982). Les protéines du lait à activité enzymatique et hormonale. Le Lait 62: 350-395.
11. Brogden KA (2005). Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria? Nat. Rev. Microbiol. 3: 238-250.
12. Callewaert L, Aertsen A, Deckers D, Vanoirbeek KGA, Vanderkelen L, Vanderkelen L, Masschalck B, Nakimbugwe D, Robben J, Van Herreweghe JM, Michiels CW (2008). A new family of lysozyme inhibitors contributing to lysozyme tolerance in gram-negative bacteria. PLos Pathog 4(3): e1000019.doi:10.1371/ journal.ppat.1000019 (open access)
13. Callewaert L, Masschalck B, Deckers D, Nakimbugwe D, Atanassova M, Aertsen A, Michiels CW (2005). Purification of Ivy, a lysozyme inhibitor from Escherichia coli, and characterisation of its specificity for various lysozymes. Enzyme Microb. Technol. 37: 205-211.
14. Chandan RC, Parry RM, Shahani KM (1968). Lysozyme, lipase, and ribonuclease in milk of various species. J. Dairy Sci. 51: 606-607.
15. Chandan RC, Shahani KM, Holly RG (1964). Lysozyme content of human milk. Nature 204: 76-77.
16. Chiang BH, Su CK, Tsai GJ, Tsao GT (2006). Egg white lysozyme purification by ultrafiltration and affinity chromatography. J. Food Sci. 58: 303-306.
17. Clare DA, Swaisgood HE (2000). Bioactive Milk Peptides: A Prospectus. J. Dairy Sci. 83: 1187-1195.
18. Clarke AJ, Dupont C (1991). O-acetylated peptidoglycan: its occurrence, pathobiological significance, and biosynthesis. Can. J. Microbiol. 38: 85-91.
19. Delfini C, Cersosimo M, Del Prete V, Strano M, Gaetano G, Pagliara A, Ambrò S (2004) Resistance screening essay of wine lactic acid bacteria on lysozyme: efficacy of lysozyme in unclarified grape musts. J. Agric. Food Chem. 52: 1861-1866.
20. Duhaiman AS (1988). Purification of camel milk lysozyme and its lytic effect on Escherichia coli and Micrococcus lysodeikticus. Comp. Biochem. Phys. 91B: 793-796.
21. Düring K, Porsch P, Mahn A, Brinkmann O, Gieffers W (1999). The non-enzymatic microbicidal activity of lysozymes. FEBS Lett. 449: 93-100.
22. El Agamy EI (2000). Effect of heat treatment on camel milk proteins with respect to antimicrobial factors: a comparison with cows' and buffalo milk proteins. Food Chem. 68: 227-232.
23. El Agamy EI, Ruppanner R, Ismail A, Champagne CP, Assaf R (1996). Purification and characterization of lactoferrin, lactoperoxidase, lysozyme and immunoglobulins from camel's milk. Int. Dairy J. 6:129-145.
24. El Agamy EI, Ruppanner R, Ismail A, Champagne CP, Assaf R (1992). Antibacterial and antiviral activity of camel milk protective proteins. J. Dairy Res. 59: 169-175.
25. El Hatmi H, Giradet JM, Gaillard JL, Yahyaoui MH, Attia H (2007). Characterization of whey proteins of camel (Camelus dromedarius) milk and colostrums. Small Rum. Res. 70: 267-271.
26. Ellison RT, Giehl TJ (1991). Killing of gram-negative bacteria by lactoferrin and lysozyme. J. Clin. Invest. 88: 1080-1091.
27. Epand RM, Vogel HJ (1999). Review Diversity of antimicrobial peptides and their mechanisms of action. Bioch. Biophs. Acta. 1462: 11-28.
28. Fernie-King BA, Seilly DJ, Binks MJ, Sriprakash KS, Lachmann PJ (2007). Streptococcal DRS (distantly related to SIC) and SIC inhibit antimicrobial peptides, components of mucosal innate immunity: a comparison of their activities. Microbes Infect. 9: 300-307.
29. Fernie-King BA, Seilly DJ, Davies A, Lachmann PJ (2002). Streptococcal inhibitor of complement inhibits two additional components of the mucosal innate immune system: secretory leukocyte proteinase inhibitor and lysozyme. Infect. Immunol. 70: 4908-4916.
30. Fleming A (1922). On a remarkable bacteriolytic element found in tissues and secretions. Proc. Roy. Soc. Ser. B. 93: 306-17.
31. Gorbenko GP, Ioffe VM, Kinnunen, Paavo KJ (2007). Binding of Lysozyme to Phospholipid Bilayers: Evidence for Protein Aggregation upon Membrane Association. Biophys. J. 93: 140-153.
32. Gow NAR (1994). Yeast hyphal dimorphism. In The Growing fungus, Edited by N.A.R. Gow & G.M. Gadd. London: Chapman & Hall. pp. 403-422.
33. Grobler JA, Rao KR, Pervaiz S, Brew K (1994). Sequences of two highly divergent canine type c lysozymes: implications for the evolutionary origins of the lysozyme/alpha-lactalbumin superfamily. Arch. Biochem. Biophys. 313: 360-366.
34. Gupta DK, Theisen N, von Figura K, Hasilik A (1985). Comparison of biosynthesis and subcellular distribution of lysozyme and lysosomal enzymes in U937 monocytes. Biochem. Biophys. Acta 847: 217-222.
35. Halper JP, Latovitzki N, Bernstein H, Beychok S (1971). Optical Activity of Human Lysozyme. Proc. Nat. Ac. Sci. (USA). 68: 517-522.
36. Hancock REW, Chapple DS (1999). Peptide antibiotics. Antimicrob. Agents Chemother. 43: 1317-1323.
37. Hayashi H, Araki Y, Ito E (1973). Occurrence of glucosamine residues with free amino groups in cell wall peptidoglycan from bacilli as a factor responsible for resistance to lysozyme. J. Bact. 113: 592-598.
38. Heinz DW, Baase WA, Matthews BW (1992). Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence. Proc. Nat. Acad. (USA). 89: 3751-3755.
39. Hennart PF, Brasseur DJ, Delogne-Desnoeck JB, Dramaix MM, Robyn CE (1991). Lysozyme, lactoferrin, and secretory immunoglobulin A content in breast milk: influence of duration of lactation, nutrition status, prolactin status, and parity of mother. Am. J. Clin, Nutr. 53:32-9.
40. Ibrahim HR, Higashiguchi S, Koketsu M, Juneja LR, Kim M, Yamamoto T (1996a). A structural phase of heat-denatured lysozyme with novel antimicrobial action. J. Agric. Food Chem. 44: 1416-1423.
41. Ibrahim HR, Kobayashi K, Kato A (1993). Length of hydrocarbon chain and antimicrobial action to gram-negative bacteria of fatty acylated lysozyme. J. Agric. Food Chem. 41: 1164-1168.
42. Ibrahim H, Higashiguchi S, Koketsu M, Juneja F, Kim M, Yamamoto T, Sugimoto Y, Aoki T (1996). Partially unfolded lysozyme at neutral pH agglutinates and kills gram-negative and gram-positive bacteria through membrane damage mechanism. J. Agric. Food. Chem. 44: 3799-3806.
43. Irwin DM (2004). Evolution of cow nonstomach lysozyme genes. Genome 47: 1082-1090.
44. Isibasi A, Santa Cruz M, Soto Montano X, Ramirez A, Kumate J (1982). Localization of a lipopeptidophosphoglycan extracted by phenol water from trophozoites of the HK-9 strain of Entamoeba histolytica. Arch. Invest. Med. 13: 57-62.
45. Jauregui-Adell J (1974). Heat stability and reactivation of mare milk lysozyme. J. Dairy Sci. 58: 835-838.
46. Jauregui-Adell J (1975). Heat stability and reactivation of mare mi1k lysozyme. J. Dairy Sci. 58: 835-838.
47. Jenssen H, Hamill P, Hancock REW (2006). Peptide Antimicrobial Agents. Clin. Microbiol. Rev. 19: 491-511.
48. Jollès J, Prager EM, Alnemri ES, Jollès P, Ibrahimi IM, Wilson AC (1990). Amino acid sequences of stomach and nonstomach lysozymes of ruminants. J. Mol. Evol. 30: 370-382.
49. Jolles P, Jolles J (1961). Lysozyme from human milk. Nature. 192:1187-1188.
50. Kappeler SR, Farah Z, Puhan Z (2003). 5-Flanking regions of camel milk genes are highly similar to homologue regions of other species and can be divided into two distinct groups. J. Dairy Sci. 86: 498-508.
51. Kihm DJ, Leyer GJ, An GH, Johnson EA (1994). Sensitization of Heat Treated Listeria monocytogenes to Added Lysozyme in Milk. Appl. Environ. Microbiol. 60: 3854-386.
52. Knorr D, Shetty KJ, Kinsella JE (2004). Enzymatic lysis of yeast cell walls. Biotechnol. Bioeng. 21: 2011- 2021.
53. Koradi R, Billeter M, Wüthrich K (1996). MOLMOL: A program for display and analysis of macromolecular structures. J. Mol. Graphics. 14: 51-55.
54. Kopp J, Schwede T (2004). The SWISS-MODEL Repository of annotated three-dimensional protein structure homology models. Nucleic Acids Res. 32: D230-D234.
55. Kuroki R, Weaver LH, Matthews BW (1999). Structural basis of the conversion of T4 lysozyme into a transglycosidase by reengineering the active site. Proc. Natl. Acad. Sci. (USA). 96: 8949-8954.
56. Lee-Huang S, Maiorov V, Huang PL, Ng A, Hee CL, Chang YT, Kallenbach N, Huang PL, Chen HC (2005). Structural and functional modeling of human lysozyme reveals a unique nonapeptide, HL9, with anti-HIV activity. Biochemistry. 44: 4648-4655.
57. Lee-Huang S, Huang PL, Sun Y, Kung Hf, Blithe DL, Chen HC (1999). Lysozyme and RNases as anti-HIV components in beta-core preparations of human chorionic gonadotropin. Proceed. Natl. Acad. Sci. (U S A). 96: 2678-2681.
58. Lemansky P, Hasilik A (2001). Chondroitin sulfate is involved in lysosomal transport of lysozyme in U937 cells. J. Cell Sci. 114: 345-352.
59. León-Sicairos N, López-Soto F, Reyes-López M, Godínez-Vargas D, Ordaz-Pichardo C, de la Garza M (2006). Amoebicidal activity of milk, apo-lactoferrin, sIgA and lysozyme. Clin. Med. Res. 4: 106-113.
60. Lonnerdal B (2004). Human milk proteins: key components for the biological activity of human milk. Adv. Exp. Med. Biol. 554: 11-25.
61. Lua D, Liua Z, Zhanga M, Liua Z, Zhoub H (2005). The mechanism of PNIPAAm-assisted refolding of lysozyme denatured by urea. Biochem. Eng. J. 24: 55-64.
62. Lundblad G, Fänge R, Slettengren K, Lind J (1979). Lysozyme, chitinase and exo-N-acetyl L□̃ D-Glucosaminidase (NAGase) in lymphomyeloid tissue of marine fishes. Marine Biol. 53: 311-315.
63. Montagne P, Cuilliere ML, Mole C, Bene MC, Faure G (2001). Changes in lactoferrin and lysozyme levels in human milk during the first twelve weeks of lactation. Adv. Exp. Med. Biol. 501: 241-247.
64. Maroni P, Cuccuri C (2001). Relationship between mammary gland infections and some milk immune parameters in Sardinian breed ewes. Small Rum. Res. 41: 1-7.
65. Martinez RJ, Carroll SF (1980). Sequential metabolic expressions of the lethal process in human serum-treated Escherichia coli: Role of lysozyme. INFECTION AND IMMUNITY, 28: 735-745.
66. Masschalck B, Deckers, D, Michiels CW (2002). Lytic and nonlytic mechanism of inactivation of gram-positive bacteria by lysozyme under atmospheric and high hydrostatic pressure. J. Food Prot. 65: 1916-23.
67. Masschalck B, Michiels CW (2003). Antimicrobial properties of lysozyme in relation to foodborne vegetative bacteria. Crit. Rev. Microbiol. 29: 191-214.
68. Masschalck B, Michiels CW (2003). Antimicrobial properties of lysozyme in relation to foodborne vegetative bacteria. Crit. Rev. Microbiol. 29: 191-214.
69. Masschalck B, Van Houdt R, Van Haver EGR, Michiels CW (2001). Inactivation of gram-negative bacteria by lysozyme, denatured lysozyme, and lysozyme-derived peptides under high hydrostatic pressure. Appl. Environ. Microbiol. 67(1): 339-344.
70. Mathur NB, Dwarkadas AM, Sharma VK, Saha K, Jain N (1990). Anti infective factors in preterm human colostrum. Acta Paediatr. Scand. 79:1039-1044.
71. Meyer K, Hahnel E, Steinberg A (1946). Lysozyme of plant origin. J. Biol. Chem. 163: 733-740.
72. Monchois V, Abergel C, Sturgis J, Jeudy S, Claverie JM (2001). Escherichia coli ykfE ORFan. (2001). Gene encodes a potent inhibitor of C-type lysozyme. J. Biol. Chem. 276: 18437-18441.
73. Montagne P, Cuillière ML, Mole C, Béńe MC, Faure G (1998). Microparticle-enhanced nephelometric immune assay of lysozyme in milk and other human body fluids. Clin. Chem. 44: 1610-1615.
74. Narita SI, Tokuda H (2007). Amino acids at positions 3 and 4 determine the membrane specificity of Pseudomonas aeruginosa lipoproteins. J. Biol. Chem. 282(18): 13372-13378.
75. Nwe N, Stevens WF, Tokura S, Tamura H (2008). Characterization of chitosan and chitosan-glucan complex extracted from the cell wall of fungus Gongronella butleri USDB 0201 by enzymatic method. Enzyme Microbial Technol. 42: 242-251.
76. O'Riordan K, Lee JC (2004). Staphylococcus aureus capsular polysaccharides. Clin. Microbiol. Rev. 17: 218-234.
77. Pahud JJ, Widmer F (1982). Calf rennet lysozyme. Biochem. J. 201: 661-664.
78. Parisien A, Allain B, Zhang J, Mandeville R, Lan CQ (2007). Novel alternatives to antibiotics: bacteriophages, bacterial cell wall hydrolases, and antimicrobial peptides. 104: 1-13.
79. Parry RM, Chandan RC Shahani KM (l960). Isolation and characterization of human milk lysozyme. Arch Biochem Bioph. 103: 59-65.
80. Pellegrini A, Thomas U, von Fellenberg R, Wild P (1992). Bactericidal activities of lysozyme and aprotinin against gram-negative and gram positive bacteria related to their basic character. J. Appl. Bacteriol. 72: 180-7.
81. Pellegrini A, Thomas U, Bramaz N, Klauser S, Hunziker P, Von Fellenberg R (1997). Identification and isolation of a bactericidal domain in chicken egg white Lysozyme. J. Appl. Microbiol. 82: 372-378.
82. Pellegrini A, Dettling C, Thomas U, Hunziker P (2001). Isolation and characterization of four bactericidal domains in the bovine β- lactoglobulin. Biochem. Bioph. Acta. 1526: 131-140.
83. Phillips DC (1967). The hen egg-white lysozyme molecule. Proc. Nat. Acad. Sci. U.S.A. 57: 484-495.
84. Piccinini R, Binda E, Belotti M, Casirani G, Zecconi A (2005). Comparison of blood and milk non-specific immune parameters in heifers after calving in relation to udder health. Vet. Res. 36: 747-757.
85. Pitotti A, Zironi R, Dal Bo A, Boschelle O (1991). Assay of lysozyme by its lytic action on Leuconostoc oenos: a suitable substrate at acidic pH. J. Food Biochem. 15: 393-403.
86. Prager EM, Wilson AC (1974). Widespread Distribution of Lysozyme in Egg White of Birds, J. Biol. Chem. 249: 7295-7297.
87. Priyadarshini S, Kansal VK (2003). Biochemical characterization of buffalo (Bubalus bubalis) milk lysozyme. Journal of Dairy Research. 70: 467-472.
88. Proctor VA, Cunningham FE (1988). The chemistry of lysozyme and its use as a food preservative and a pharmaceutical. Crit. Rev. Food Sci. Nutr. 26: 359-395.
89. Ralph P, Moore MAS, Nilsson K (1976). Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines. J. Exp. Med. 143: 1528-1533.
90. Razavi-Rohani SM, Griffiths MW (1999). The Antifungal Activity Of Butylated Hydroxyanizole And Lysozyme. J. Food Safety. 19: 97-108.
91. Reddy KVR, Yedery RD, Aranha C (2004). Antimicrobial peptides: premises and promises; Review. 2004. Int. J. Antimicrob. Agens. 24:536-547.
92. Repaske R (1956). Lysis of gram-negative bacteria by lysozyme. Biochem. Biophys. Acta. 22: 189-191.
93. Salimei E, Fantuz F, Coppola R, Chiofalo B, Polidor P, Varisco G (2004). Composition and characteristics of ass's milk. Anim. Res. 53: 67-78.
94. Salton MRJ (1957). The properties of lysozyme and its action on microorganisms. Bacteriol. Revs. 21: 82-100. Sarwar A, Enbergs H, Klug E (2001). Influences of parity, age and mineral and trace element mixture on lysozyme activity in mare's milk during early lactation period. Vet. Arhiv 71: 139-147.
95. Sauter EA, Montoure JE (1972). The relationship of lysozyme content of egg white to volume and stability of foams. J. Food Sci. 37: 6, 918.
96. Schulze F, Muller G (1980). Lysozyme in sow's milk and its importance to bacterial population of the gastrointestinal tract in suckling piglets. Arch Exp. Veterinarmed. 34: 317-24.
97. Severin S, Wenshui X (2005). Milk biologically active components as nutraceuticals: Review. Crit. Rev. Food Sci. Nutr. 45: 645-656.
98. Sexton C, Buss DH, Powell B, O'Connor M, Rainer R, Woodruff R, Cruz J, Pettenati M, Rao PN, Case LD (1996). Usefulness and limitations of serum and urine lysozyme levels in the classification of acute myeloid leukemia: An analysis of 208 cases. Leukemia Res. 20: 467-472.
99. Shahriar F, Gordon JR, Simko E (2006). Identification of lipopolysaccharide-binding proteins in porcine milk. Can. J. Vet. Res. 70: 243-250.
100. Schulze F, Muller G (1980). Lysozyme in sow's milk and its importance
101. to bacterial population of the gastrointestinal tract in suckling piglets. Arch. Exp. Veterinarmed. 34: 317-24.
102. Sinnott ML (1990). Catalytic mechanisms of enzymic glycosyl transfer. Chem. Rev. 90: 1171-1202.
103. Solaroli G, Pagliarini E, Peri C (1993). Composition and nutritional quality of mare's milk, Ital. J.Food Sci. 1: 3-10.
104. Stark M, Liu LP, Deber CM (2002). Cationic hydrophobic peptides with antimicrobial activity. Antimicrobial Agents Chemother. 46: 3585-3590.
105. Tokuda H, Matsuyama SI (2004). Sorting of lipoproteins to the outer membrane in E. coli. Biochem. Bioph. Acta 1693: 5-13.
106. Touch V, Hayakawa S, Saitoh K (2004). Relationships between conformational changes and antimicrobial activity of lysozyme upon reduction of its disulfide bonds. Food Chem. 84: 421-428.
107. Vaara M (1992). Agents that increase the permeability of the outer membrane. Microbiol. Rev. 56: 395-411.
108. Vakil JR, Chabldan RCM Parry R, Shahani KM (1969). Susceptibility of Several Microorganisms to Milk Lysozymes. J. Dairy Sci. 52: 1192-1197.
109. Varaldo PE, Valisena S, Mingari MC, Satta G (1989). Lysozyme induced inhibition of the lymphocyte response to mitogenic lectins. Proceed. Soc. Exp. Biol. Med. 190: 54-62.
110. Veiga P, Piquet S, Maisons A, Furlan S, Courtin P, Chapot-Chartier MP, Kulakauskas S (2006). Identifcation of an essential gene responsible for D-Asp incorporation in the Lactococcus lactis peptidoglycan crossbridge. Mol. Microbiol. 62: 1713-1724.
111. Veiga P, Piquet S, Maisons A, Furlan S, Courtin P, Chapot-Chartier MP, Kulakauskas S (2006) Identification of an essential gene responsible for d-Aspin corporation in the Lactococcus lactis peptidoglycan crossbridge. Mol. Microbiol 62: 1713-1724.
112. Vocadlo DJ, Davies GJ, Laine R, Withers SG (2001). Catalysis by hen egg white lysozyme proceeds via a covalent intermediate. Nature. 412: 835-3838.
113. Vollmer W, Tomasz A (2000). The pgdA gene encodes for a peptidoglycan N-Acetylglucosamine deacetylase in Streptococcus pneumonia. J. Biol. Chem. 275: 20496-20501.
114. Wang S, Ng TB, Chen T, Lin D, Wu J, Rao P, Ye X (2005). First report of a novel plant lysozyme with both antifungal and antibacterial activities. Biochem Biophy. Res. Commun. 327: 820-827.
115. Wang J, Hu B, Xu M, Yan Q, Liu S, Zhu X, Sun Z, Tao D (2006) Therapeutic effectiveness of bacteriophages in the rescue of mice with extended spectrum beta-lactamase-producing Escherichia coli bacteremia. Int. J. Mol. Med. 17: 347-355.
116. Wilcox FH, Cole RK (1957). The inheritance of differences in the lysozyme level of Hens' egg white genetics. 42: 264-272.
117. Wolin MJ (1966). Lysis of Vibrio suvcinogenes by ethylenediaminetetraacetic acid or lysozyme. J. Bacteriol. 91: 1781-1786.
118. Wu T, Samaranayake LP, Leung WK, Sullivan PA (1999). Inhibition of growth and secreted aspartyl proteinase production in Candida albicans by lysozyme. J. Med. microbiol. 48: 721-730.
119. Wu MH, Maier E, Benz R., and Hancock, R.E.W. 1999. Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli. Biochemistry-US. 38: 7235-7242.
120. Xue QG, Schey KL, Volety AK, Chu FL, La Peyre JF (2004). Purification and characterization of lysozyme from plasma of the eastern oyster (Crassostrea virginica). Comp. Biochem. Physiol. B Biochem. Mol. Biol. 139: 11-25.