Na+/H+ exchange inhibitor cariporide attenuates skeletal muscle infarction when administered before ischemia or reperfusion

Journal of Applied Physiology

Volumn 106, Issue 1, 2009, Pages 20-28

  McAllister, Sandra E ^a,b   Moses, Michael A ^a,b   Jindal, Kunaal ^a   Ashrafpour, Homa ^a   Cahoon, Neil J ^a,b   Huang, Ning ^a   Neligan, Peter C ^a,b,d   Forrest, Christopher R ^a,b   Lipa, Joan E ^a,b   Pang, Cho Y ^a,b,c  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b Salvation Army Scarborough Grace H   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Atp synthesis; Ischemia reperfusion injury; Mitochondrial free ca2+ overload

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA ACTIN; CALCIUM; CARIPORIDE; MYELOPEROXIDASE; SODIUM PROTON EXCHANGE PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ELECTIVE SURGERY; ENZYME ACTIVITY; INFARCTION; LATISSIMUS DORSI FLAP; MUSCLE ISCHEMIA; MUSCLE MITOCHONDRION; MUSCLE NECROSIS; NEUTROPHIL; NONHUMAN; PLASTIC SURGERY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; SKELETAL MUSCLE INFARCTION; SWINE; SYNTHESIS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CASTRATION; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; ENZYME INHIBITORS; GUANIDINES; INFARCTION; INJECTIONS, INTRAVENOUS; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; NECROSIS; NEUTROPHIL INFILTRATION; NEUTROPHILS; PEROXIDASE; REPERFUSION INJURY; SODIUM-HYDROGEN ANTIPORTER; SULFONES; SURGICAL FLAPS; SWINE; TIME FACTORS;

EID: 58649089623     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.91069.2008     Document Type: Article

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