Inhibition of the Na+/H+ exchanger attenuates phase 1b ischemic arrhythmias and reperfusion-induced ventricular fibrillation

European Journal of Pharmacology

Volumn 396, Issue 2-3, 2000, Pages 119-124

  Gumina, Richard J ^a,c   Daemmgen, Juergen ^b   Gross, Garrett J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^c MAYO CLINIC   (United States)

Author keywords

Arrhythmias; Myocardial infarct size; Sodium hydrogen exchanger

Indexed keywords

[4 [4 (2 FUROYL) 1 PIPERAZINYL] 3 (METHYLSULFONYL)BENZOYL]GUANIDINE; BENZAMIDE DERIVATIVE; BENZAMIDE,N (AMINOIMINOMETHYL) 4 [4 (2 FURANYLCARBONYL) 1 PIPERAZINYL] 3 (METHYLSULFONYL), METHANESULFONATE; ENZYME INHIBITOR; NHE 1; NHE 1 INHIBITOR; PROTON; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIARRHYTHMIC ACTIVITY; ARTICLE; BLOOD GAS; CONTROLLED STUDY; DOG; DOSE TIME EFFECT RELATION; DRUG INFUSION; ELECTROCARDIOGRAM; FEMALE; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART VENTRICLE FIBRILLATION; HEMODYNAMICS; ION EXCHANGE; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; STAINING;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIA; DOGS; FEMALE; HEMODYNAMIC PROCESSES; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; SODIUM-HYDROGEN ANTIPORTER; VENTRICULAR FIBRILLATION;

EID: 0034685967     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00200-4     Document Type: Article

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