Reduction of myocardial infarct size by SM-198110, a novel Na +/H+ exchange inhibitor, in rabbits

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 371, Issue 5, 2005, Pages 408-419

  Yamada, Kazuto ^a   Matsui, Kazuki ^a   Ogawa, Shoji ^a   Yamamoto, Setsuko ^a   Mori, Masaya ^a   Kitano, Masahumi ^a   Ohashi, Naohito ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

Ischaemic preconditioning; KATP channel; Myocardial ischaemia and reperfusion injury; Na+ H+ exchange

Indexed keywords

3 [2 [[[AMINO(IMINO)METHYL]AMINO]CARBONYL] 4 CHLORO 1H INDOL 1 YL] 1 PROPANESULFONIC ACID; 5 HYDROXYDECANOIC ACID; 8 (4 SULFOPHENYL)THEOPHYLLINE; ADENOSINE RECEPTOR BLOCKING AGENT; CARIPORIDE; CREATINE KINASE; GLIBENCLAMIDE; POTASSIUM CHANNEL BLOCKING AGENT; SM 198110; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVITY; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART RATE; LOW DRUG DOSE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; RABBIT; REPERFUSION INJURY;

ALKANESULFONIC ACIDS; ANIMALS; BLOOD PRESSURE; CREATINE KINASE; GUANIDINES; HEART RATE; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; NECROSIS; PHOSPHOPROTEINS; RABBITS; SODIUM-HYDROGEN ANTIPORTER; SULFONES;

EID: 23944516054     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-005-1062-6     Document Type: Article

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