-
1
-
-
33745906976
-
Quantitative bioluminescence imaging of transgene expression in vivo
-
Rettig GR, McAnuff M, Liu D, Kim JS, Rice KG. Quantitative bioluminescence imaging of transgene expression in vivo. Anal Biochem 2006;355:90-4.
-
(2006)
Anal Biochem
, vol.355
, pp. 90-94
-
-
Rettig, G.R.1
McAnuff, M.2
Liu, D.3
Kim, J.S.4
Rice, K.G.5
-
2
-
-
0036405345
-
Advances in in vivo bioluminescence imaging of gene expression
-
Contag CH, Bachmann MH. Advances in in vivo bioluminescence imaging of gene expression. Annu Rev Biomed Eng 2002;4:235-60.
-
(2002)
Annu Rev Biomed Eng
, vol.4
, pp. 235-260
-
-
Contag, C.H.1
Bachmann, M.H.2
-
3
-
-
0036793192
-
It's not just about anatomy: In vivo bioluminescence imaging as an eyepiece into biology
-
Contag CH, Ross BD. It's not just about anatomy: In vivo bioluminescence imaging as an eyepiece into biology. J Magn Reson Imaging 2002;16:378-87.
-
(2002)
J Magn Reson Imaging
, vol.16
, pp. 378-387
-
-
Contag, C.H.1
Ross, B.D.2
-
4
-
-
2442437836
-
Biotechnological applications of bioluminescence and chemiluminescence
-
Roda A, Pasini P, Mirasoli M, Michelini E, Guardigli M. Biotechnological applications of bioluminescence and chemiluminescence. Trends Biotechnol 2004;22:295-303.
-
(2004)
Trends Biotechnol
, vol.22
, pp. 295-303
-
-
Roda, A.1
Pasini, P.2
Mirasoli, M.3
Michelini, E.4
Guardigli, M.5
-
5
-
-
33745698850
-
In vivo imaging using bioluminescence: A tool for probing graft-versus-host disease
-
Negrin RS, Contag CH. In vivo imaging using bioluminescence: a tool for probing graft-versus-host disease. Nat Rev Immunol 2006;6:484-90.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 484-490
-
-
Negrin, R.S.1
Contag, C.H.2
-
6
-
-
16344363226
-
Molecular optical imaging: Applications leading to the development of present day therapeutics
-
Shah K, Weissleder R. Molecular optical imaging: applications leading to the development of present day therapeutics. NeuroRx 2005;2:215-25.
-
(2005)
NeuroRx
, vol.2
, pp. 215-225
-
-
Shah, K.1
Weissleder, R.2
-
7
-
-
1242342217
-
Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine
-
Pichler A, Prior JL, Piwnica-Worms D. Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine. Proc Natl Acad Sci U S A 2004;101:1702-7.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1702-1707
-
-
Pichler, A.1
Prior, J.L.2
Piwnica-Worms, D.3
-
8
-
-
0034681266
-
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
-
Wang B, Fallon JF, Beachy PA. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 2000;100:423-34.
-
(2000)
Cell
, vol.100
, pp. 423-434
-
-
Wang, B.1
Fallon, J.F.2
Beachy, P.A.3
-
9
-
-
0037200078
-
Medulloblastoma growth inhibition by hedgehog pathway blockade
-
Berman DM, Karhadkar SS, Hallahan AR, et al. Medulloblastoma growth inhibition by hedgehog pathway blockade. Science 2002;297:1559-61.
-
(2002)
Science
, vol.297
, pp. 1559-1561
-
-
Berman, D.M.1
Karhadkar, S.S.2
Hallahan, A.R.3
-
10
-
-
0347382812
-
Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity
-
Robey RW, Honjo Y, Morisaki K, et al. Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity. Br J Cancer 2003;89:1971-8.
-
(2003)
Br J Cancer
, vol.89
, pp. 1971-1978
-
-
Robey, R.W.1
Honjo, Y.2
Morisaki, K.3
-
11
-
-
4544285754
-
Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice
-
Romer JT, Kimura H, Magdaleno S, et al. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. Cancer Cell 2004;6:229-40.
-
(2004)
Cancer Cell
, vol.6
, pp. 229-240
-
-
Romer, J.T.1
Kimura, H.2
Magdaleno, S.3
-
12
-
-
35148858663
-
Mediators of hedgehog pathways, compositions and uses related thereto
-
US Patent no. WO03011219
-
Rubin LL, Guicherit OM, Price S, Boyd EA. Mediators of hedgehog pathways, compositions and uses related thereto. US Patent no. WO03011219: 2003.
-
(2003)
-
-
Rubin, L.L.1
Guicherit, O.M.2
Price, S.3
Boyd, E.A.4
-
13
-
-
1242338786
-
Imaging tri-fusion multimodality reporter gene expression in living subjects
-
Ray P, De A, Min JJ, Tsien RY, Gambhir SS. Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res 2004;64:1323-30.
-
(2004)
Cancer Res
, vol.64
, pp. 1323-1330
-
-
Ray, P.1
De, A.2
Min, J.J.3
Tsien, R.Y.4
Gambhir, S.S.5
-
14
-
-
0030891148
-
A binding site for Gli proteins is essential for HNF-3β floor plate enhancer activity in transgenics and can respond to Shh in vitro
-
Sasaki H, Hui C, Nakafuku M, Kondoh H. A binding site for Gli proteins is essential for HNF-3β floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development 1997;124:1313-22.
-
(1997)
Development
, vol.124
, pp. 1313-1322
-
-
Sasaki, H.1
Hui, C.2
Nakafuku, M.3
Kondoh, H.4
-
15
-
-
0033761448
-
Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities
-
Aza-Blanc P, Lin HY, Ruiz i Altaba A, Kornberg TB. Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities. Development 2000;127:4293-301.
-
(2000)
Development
, vol.127
, pp. 4293-4301
-
-
Aza-Blanc, P.1
Lin, H.Y.2
Ruiz i Altaba, A.3
Kornberg, T.B.4
-
17
-
-
20444468917
-
Targeting medulloblastoma: Small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics
-
Romer J, Curran T. Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics. Cancer Res 2005;65:4975-8.
-
(2005)
Cancer Res
, vol.65
, pp. 4975-4978
-
-
Romer, J.1
Curran, T.2
-
18
-
-
0023691409
-
Verapamil reversal of doxorubicin resistance in multidrug-resistant human myeloma cells and association with drug accumulation and DNA damage
-
Bellamy WT, Dalton WS, Kailey JM, et al. Verapamil reversal of doxorubicin resistance in multidrug-resistant human myeloma cells and association with drug accumulation and DNA damage. Cancer Res 1988;48:6365-70.
-
(1988)
Cancer Res
, vol.48
, pp. 6365-6370
-
-
Bellamy, W.T.1
Dalton, W.S.2
Kailey, J.M.3
-
19
-
-
0031053478
-
Indomethacin-mediated reversal of multidrug resistance and drug efflux in human and murine cell lines overexpressing MRP, but not P-glycoprotein
-
Draper MP, Martell RL, Levy SB. Indomethacin-mediated reversal of multidrug resistance and drug efflux in human and murine cell lines overexpressing MRP, but not P-glycoprotein. Br J Cancer 1997;75:810-5.
-
(1997)
Br J Cancer
, vol.75
, pp. 810-815
-
-
Draper, M.P.1
Martell, R.L.2
Levy, S.B.3
-
20
-
-
0033966957
-
Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein
-
Rabindran SK, Ross DD, Doyle LA, Yang W, Greenberger LM. Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res 2000;60:47-50.
-
(2000)
Cancer Res
, vol.60
, pp. 47-50
-
-
Rabindran, S.K.1
Ross, D.D.2
Doyle, L.A.3
Yang, W.4
Greenberger, L.M.5
-
21
-
-
0035815988
-
A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)
-
Robey RW, Honjo Y, van de Laar A, et al. A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2). Biochim Biophys Acta 2001;1512:171-82.
-
(2001)
Biochim Biophys Acta
, vol.1512
, pp. 171-182
-
-
Robey, R.W.1
Honjo, Y.2
van de Laar, A.3
-
22
-
-
33646787078
-
3H]PCV for monitoring reporter gene expression of wild type and mutant herpes simplex virus type 1 thymidine kinase in cell culture
-
3H]PCV for monitoring reporter gene expression of wild type and mutant herpes simplex virus type 1 thymidine kinase in cell culture. Mol Imaging Biol 2005;7:296-303.
-
(2005)
Mol Imaging Biol
, vol.7
, pp. 296-303
-
-
Kang, K.W.1
Min, J.J.2
Chen, X.3
Gambhir, S.S.4
-
23
-
-
0032946379
-
The multidrug resistance-associated protein (MRP) is over-expressed and functional in rat hepatoma cells
-
Payen L, Courtois A, Vernhet L, Guillouzo A, Fardel O. The multidrug resistance-associated protein (MRP) is over-expressed and functional in rat hepatoma cells. Int J Cancer 1999;81:479-85.
-
(1999)
Int J Cancer
, vol.81
, pp. 479-485
-
-
Payen, L.1
Courtois, A.2
Vernhet, L.3
Guillouzo, A.4
Fardel, O.5
-
24
-
-
23144448901
-
Real-time imaging of ligand-induced IKK activation in intact cells and in living mice
-
Gross S, Piwnica-Worms D. Real-time imaging of ligand-induced IKK activation in intact cells and in living mice. Nat Methods 2005;2:607-14.
-
(2005)
Nat Methods
, vol.2
, pp. 607-614
-
-
Gross, S.1
Piwnica-Worms, D.2
-
25
-
-
13444288036
-
Breast cancer resistance protein (BCRP/ABCG2)
-
Staud F, Pavek P. Breast cancer resistance protein (BCRP/ABCG2). Int J Biochem Cell Biol 2005;37:720-5.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 720-725
-
-
Staud, F.1
Pavek, P.2
-
26
-
-
30344444454
-
The function of breast cancer resistance protein in epithelial barriers, stem cells and milksecretion of drugs and xenotoxins
-
van Herwaarden AE, Schinkel AH. The function of breast cancer resistance protein in epithelial barriers, stem cells and milksecretion of drugs and xenotoxins. Trends Pharmacol Sci 2006;27:10-6.
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 10-16
-
-
van Herwaarden, A.E.1
Schinkel, A.H.2
-
27
-
-
14044250981
-
Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo
-
Tannous BA, Kim DE, Fernandez JL, Weissleder R, Breakefield XO. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther 2005;11:435-43.
-
(2005)
Mol Ther
, vol.11
, pp. 435-443
-
-
Tannous, B.A.1
Kim, D.E.2
Fernandez, J.L.3
Weissleder, R.4
Breakefield, X.O.5
-
28
-
-
0037039437
-
Optical imaging of Renilla luciferase reporter gene expression in living mice
-
Bhaumik S, Gambhir SS. Optical imaging of Renilla luciferase reporter gene expression in living mice. Proc Natl Acad Sci U S A 2002;99:377-82.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 377-382
-
-
Bhaumik, S.1
Gambhir, S.S.2
-
29
-
-
0037502209
-
Time course of bioluminescent signal in orthotopic and heterotopic brain tumors in nude mice
-
Burgos JS, Rosol M, Moats RA, et al. Time course of bioluminescent signal in orthotopic and heterotopic brain tumors in nude mice. Biotechniques 2003;34:1184-8.
-
(2003)
Biotechniques
, vol.34
, pp. 1184-1188
-
-
Burgos, J.S.1
Rosol, M.2
Moats, R.A.3
-
30
-
-
30344487254
-
Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs
-
Breedveld P, Beijnen JH, Schellens JH. Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs. Trends Pharmacol Sci 2006;27:17-24.
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 17-24
-
-
Breedveld, P.1
Beijnen, J.H.2
Schellens, J.H.3
-
31
-
-
0043027091
-
A transgenic mouse model with a luciferase reporter for studying in vivo transcriptional regulation of the human CYP3A4 gene
-
Zhang W, Purchio AF, Chen K, et al. A transgenic mouse model with a luciferase reporter for studying in vivo transcriptional regulation of the human CYP3A4 gene. Drug Metab Dispos 2003;31:1054-64.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1054-1064
-
-
Zhang, W.1
Purchio, A.F.2
Chen, K.3
-
32
-
-
17844372454
-
Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver
-
Merino G, van Herwaarden AE, Wagenaar E, Jonker JW, Schinkel AH. Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver. Mol Pharmacol 2005;67:1765-71.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1765-1771
-
-
Merino, G.1
van Herwaarden, A.E.2
Wagenaar, E.3
Jonker, J.W.4
Schinkel, A.H.5
-
33
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakacs G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM. Targeting multidrug resistance in cancer. Nat Rev Drug Discov 2006;5:219-34.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 219-234
-
-
Szakacs, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
34
-
-
2442719906
-
Unmasking the dynamic interplay between efflux transporters and metabolic enzymes
-
Benet LZ, Cummins CL, Wu CY. Unmasking the dynamic interplay between efflux transporters and metabolic enzymes. Int J Pharm 2004;277:3-9.
-
(2004)
Int J Pharm
, vol.277
, pp. 3-9
-
-
Benet, L.Z.1
Cummins, C.L.2
Wu, C.Y.3
-
35
-
-
29244448268
-
BCRP transports dipyridamole and is inhibited by calcium channel blockers
-
Zhang Y, Gupta A, Wang H, et al. BCRP transports dipyridamole and is inhibited by calcium channel blockers. Pharm Res 2005;22:2023-34.
-
(2005)
Pharm Res
, vol.22
, pp. 2023-2034
-
-
Zhang, Y.1
Gupta, A.2
Wang, H.3
-
36
-
-
33846664466
-
ATP-binding cassette, subfamily G (ABCG family)
-
Kusuhara H, Sugiyama Y. ATP-binding cassette, subfamily G (ABCG family). Pflugers Arch 2007;453:735-44.
-
(2007)
Pflugers Arch
, vol.453
, pp. 735-744
-
-
Kusuhara, H.1
Sugiyama, Y.2
-
37
-
-
33747086613
-
Breast cancer resistance protein in pharmacokinetics and drug-drug interactions. Expert Opin Drug Metab
-
Xia CQ, Yang JJ, Gan LS. Breast cancer resistance protein in pharmacokinetics and drug-drug interactions. Expert Opin Drug Metab Toxicol 2005;1:595-611.
-
(2005)
Toxicol
, vol.1
, pp. 595-611
-
-
Xia, C.Q.1
Yang, J.J.2
Gan, L.S.3
-
38
-
-
2342644918
-
Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier
-
Cisternino S, Mercier C, Bourasset F, Roux F, Scherrmann JM. Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier. Cancer Res 2004;64:3296-301.
-
(2004)
Cancer Res
, vol.64
, pp. 3296-3301
-
-
Cisternino, S.1
Mercier, C.2
Bourasset, F.3
Roux, F.4
Scherrmann, J.M.5
-
39
-
-
1642454475
-
ABC transporters and the blood-brain barrier
-
Begley DJ. ABC transporters and the blood-brain barrier. Curr Pharm Des 2004;10:1295-312.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 1295-1312
-
-
Begley, D.J.1
-
40
-
-
33644945723
-
A high-throughput cell-based assay for inhibitors of ABCG2 activity
-
Henrich CJ, Bokesch HR, Dean M, et al. A high-throughput cell-based assay for inhibitors of ABCG2 activity. J Biomol Screen 2006;11:176-83.
-
(2006)
J Biomol Screen
, vol.11
, pp. 176-183
-
-
Henrich, C.J.1
Bokesch, H.R.2
Dean, M.3
|