Novel haem co-ordination variants of flavocytochrome P450 BM3

Biochemical Journal

Volumn 417, Issue 1, 2009, Pages 65-76

  Girvan, Hazel M ^a   Toogood, Helen S ^a   Littleford, Rachael E ^b   Seward, Harriet E ^c   Smith, W Ewen ^b   Ekanem, Idorenyin S ^a   Leys, David ^a   Cheesman, Myles R ^d   Munro, Andrew W ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

^d UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Cytochrome P450; Electron paramagnetic resonance (EPR); Haem co ordination; Magnetic circular dichroism (MCD); P450 BM3

Indexed keywords

CYTOCHROME P450; ELECTRON PARAMAGNETIC RESONANCE (EPR); HAEM CO-ORDINATION; MAGNETIC CIRCULAR DICHROISM (MCD); P450 BM3;

AMINES; AMINO ACIDS; BACTERIOLOGY; CRYSTAL STRUCTURE; DICHROISM; ELECTRON RESONANCE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FATTY ACIDS; LIGANDS; MAGNETIC DOMAINS; ORGANIC ACIDS; PARAMAGNETIC MATERIALS; PARAMAGNETIC RESONANCE; PARAMAGNETISM; QUANTUM THEORY; SPECTRUM ANALYSIS; THERMODYNAMIC PROPERTIES;

SUBSTRATES;

ALANINE; CYSTEINE; CYTOCHROME P450 BM3; HEME; BACTERIAL PROTEIN; CYTOCHROME P450; FATTY ACID; FLAVOCYTOCHROME P450 BM3 MONOXYGENASES; GLUTAMINE; METHIONINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ELECTRON SPIN RESONANCE; ENZYME BINDING; ENZYME CONFORMATION; GENETIC VARIABILITY; MUTANT; PRIORITY JOURNAL; PROTEIN DOMAIN; THERMODYNAMICS; WILD TYPE; CHEMISTRY; CIRCULAR DICHROISM; GENETICS; KINETICS; METABOLISM; MUTATION; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS;

BACILLUS MEGATERIUM;

BACTERIAL PROTEINS; CIRCULAR DICHROISM; CYTOCHROME P-450 ENZYME SYSTEM; ELECTRON SPIN RESONANCE SPECTROSCOPY; FATTY ACIDS; GLUTAMINE; HEME; KINETICS; METHIONINE; MUTAGENESIS, SITE-DIRECTED; MUTATION; NADPH-FERRIHEMOPROTEIN REDUCTASE; PROTEIN BINDING; THERMODYNAMICS;

EID: 58249083277     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20081133     Document Type: Article

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