Substrate modulation of the properties and reactivity of the oxy-ferrous and hydroperoxo-ferric intermediates of cytochrome P450cam as shown by cryoreduction-EPR/ENDOR spectroscopy

Journal of the American Chemical Society

Volumn 127, Issue 5, 2005, Pages 1403-1413

  Davydov, Roman ^a   Perera, Roshan ^b   Jin, Shengxi ^b   Yang, Tran Chin ^a   Bryson, Thomas A ^b   Sono, Masanori ^b   Dawson, John H ^b   Hoffman, Brian M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANNEALING; CRYOGENICS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYMES; GAMMA RAYS; HYDROXYLATION; IRRADIATION; MODULATION; PIGMENTS; REDUCTION; SUBSTRATES;

Γ-IRRADIATION; HYDROOXYLATION SUBSTRATES; OXYFERROUS CYTOCHROME; SUBSTRATE MODULATION;

IRON COMPOUNDS;

5 METHYLENYL CAMPHOR; 5,5 DIFLUOROCAMPHOR; CAMPHOR; CAMPHOR 5 MONOOXYGENASE; CAMPHOR DERIVATIVE; EPOXIDE; HEME DERIVATIVE; HYDROGEN PEROXIDE; NORCAMPHOR; UNCLASSIFIED DRUG;

ARTICLE; ELECTRON NUCLEAR DOUBLE RESONANCE; ELECTRON SPIN RESONANCE; GAMMA IRRADIATION; HYDROXYLATION; MODULATION;

ADAMANTANE; BINDING SITES; CAMPHOR; CAMPHOR 5-MONOOXYGENASE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FERRIC COMPOUNDS; FERROUS COMPOUNDS; HYDROXYLATION; MODELS, MOLECULAR; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 13444266016     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja045351i     Document Type: Article

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