An n-3 PUFA-rich microalgal oil diet protects to a similar extent as a fish oil-rich diet against AOM-induced colonic aberrant crypt foci in F344 rats

Food and Chemical Toxicology

Volumn 47, Issue 2, 2009, Pages 316-320

  van Beelen, Vincent A ^a   Spenkelink, Bert ^a   Mooibroek, Hans ^a   Sijtsma, Lolke ^a   Bosch, Dirk ^a   Rietjens, Ivonne M C M ^a   Alink, Gerrit M ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Aberrant crypt foci; Chemoprevention; Colon cancer; Fish oil; Lipid peroxidation; Microalgal oil

Indexed keywords

AZOXYMETHANE; CARCINOGEN; CORN OIL; FATTY ACID; FISH OIL; MICROALGAL OIL; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER PREVENTION; COLON CANCER; COLON CARCINOGENESIS; DIETARY INTAKE; FECES ANALYSIS; FISCHER 344 RAT; INTESTINE CRYPT; LIPID ANALYSIS; LIPID PEROXIDATION; MALE; MICROALGA; NONHUMAN; RAT;

ALGAE; ANIMAL FEED; ANIMALS; AZOXYMETHANE; CARCINOGENS; COLONIC NEOPLASMS; CORN OIL; DIETARY FATS; DISEASE MODELS, ANIMAL; FATTY ACIDS, OMEGA-3; FISH OILS; INTESTINAL MUCOSA; MALE; OXIDATIVE STRESS; PLANT OILS; PRECANCEROUS CONDITIONS; RATS; RATS, INBRED F344;

RATTUS; ZEA MAYS;

EID: 58149503743     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.11.014     Document Type: Article

References (33)

1. Augustsson K., Michaud D.S., Rimm E.B., Leitzmann M.F., Stampfer M.J., Willett W.C., and Giovannucci E. A prospective study of intake of fish and marine fatty acids and prostate cancer. Cancer Epidemiol. Biomark. Prev. 12 (2003) 64-67
2. Bird R.P. Role of aberrant crypt foci in understanding the pathogenesis of colon cancer. Cancer Lett. 93 (1995) 55-71
3. Buege J.A., and Aust S.D. Microsomal lipid peroxidation. Meth. Enzymol. 52 (1978) 302-310
4. Butte W. Rapid method for the determination of fatty acid profiles from fats and oils using trimethylsulphonium hydroxide for transesterification. J. Chromatogr. 261 (1983) 142-145
5. Cheng J., Ogawa K., Kuriki K., Yokoyama Y., Kamiya T., Seno K., Okuyama H., Wang J., Luo C., Fujii T., Ichikawa H., Shirai T., and Tokudome S. Increased intake of n-3 polyunsaturated fatty acids elevates the level of apoptosis in the normal sigmoid colon of patients polypectomized for adenomas/tumors. Cancer Lett. 193 (2003) 17-24
6. Cheng L., and Lai M.D. Aberrant crypt foci as microscopic precursors of colorectal cancer. World J. Gastroenterol. 9 (2003) 2642-2649
7. Christie W.W. Gas Chromatography and Lipids (1989), Oily Press, Bridgewater
8. Corpet D.E., and Taché S. Most effective colon cancer chemopreventive agents in rats: a systematic review of aberrant crypt foci and tumor data, ranked by potency. Nutr. Cancer 43 (2002) 1-21
9. Deschner E.E., Lytle J.S., Wong G., Ruperto J.F., and Newmark H.L. The effect of dietary omega-3 fatty acids (fish oil) on azoxymethanol-induced focal areas of dysplasia and colon tumor incidence. Cancer 66 (1990) 2350-2356
10. Dommels Y.E., Haring M.M., Keestra N.G., Alink G.M., Van Bladeren P.J., and Van Ommen B. The role of cyclooxygenase in n-6 and n-3 polyunsaturated fatty acid mediated effects on cell proliferation, PGE(2) synthesis and cytotoxicity in human colorectal carcinoma cell lines. Carcinogenesis 24 (2003) 385-392
11. Dommels Y.E., Heemskerk S., Van Den Berg H., Alink G.M., Van Bladeren P.J., and Van Ommen B. Effects of high fat fish oil and high fat corn oil diets on initiation of AOM-induced colonic aberrant crypt foci in male F344 rats. Food Chem. Toxicol. 41 (2003) 1739-1747
12. Gao L., Wang J., Sekhar K.R., Yin H., Yared N.F., Schneider S.N., Sasi S., Dalton T.P., Anderson M.E., Chan J.Y., Morrow J.D., and Freeman M.L. Novel N-3 fatty acid oxidation products activate Nrf2 by destabilizing the association between keap1 and cullin3. J Biol Chem. 282 (2007) 2529-2537
13. Hong M.Y., Lupton J.R., Morris J.S., Wang N., Carroll R.J., Davidson L.A., Elder R.H., and Chapkin R.S. Dietary fish oil reduces O6-methylguanine DNA adduct levels in rat colon in part by increasing apoptosis during tumor initiation. Cancer Epidemiol. Biomark. Prev. 9 (2000) 819-826
14. Latham P., Lund E.K., and Johnson I.T. Dietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon. Carcinogenesis 20 (1999) 645-650
15. Levonen A.L., Landar A., Ramachandran A., Ceaser E.K., Dickinson D.A., Zanoni G., Morrow J.D., and Darley-Usmar V.M. Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products. Biochem. J. 378 (2004) 373-382
16. Magnuson B.A., Carr I., and Bird R.P. Ability of aberrant crypt foci characteristics to predict colonic tumor incidence in rats fed cholic acid. Cancer Res. 53 (1993) 4499-4504
17. Minoura T., Takata T., Sakaguchi M., Takada H., Yamamura M., Hioki K., and Yamamoto M. Effect of dietary eicosapentaenoic acid on azoxymethane-induced colon carcinogenesis in rats. Cancer Res. 48 (1988) 4790-4794
18. Narayanan B.A., Narayanan N.K., and Reddy B.S. Docosahexaenoic acid regulated genes and transcription factors inducing apoptosis in human colon cancer cells. Int. J. Oncol. 19 (2001) 1255-1262
19. Nelson R.L., Tanure J.C., Andrianopoulos G., Souza G., and Lands W.E. A comparison of dietary fish oil and corn oil in experimental colorectal carcinogenesis. Nutr. Cancer 11 (1988) 215-220
20. Pretlow T.P., O'Riordan M.A., Somich G.A., Amini S.B., and Pretlow T.G. Aberrant crypts correlate with tumor incidence in F344 rats treated with azoxymethane and phytate. Carcinogenesis 13 (1992) 1509-1512
21. Pulz O., and Gross W. Valuable products from biotechnology of microalgae. Appl. Microbiol. Biotechnol. 65 (2004) 635-648
22. Rao C.V., Hirose Y., Indranie C., and Reddy B.S. Modulation of experimental colon tumorigenesis by types and amounts of dietary fatty acids. Cancer Res. 61 (2001) 1927-1933
23. Reddy B.S., and Sugie S. Effect of different levels of omega-3 and omega-6 fatty acids on azoxymethane-induced colon carcinogenesis in F344 rats. Cancer Res. 48 (1988) 6642-6647
24. Sijtsma L., and De Swaaf M.E. Biotechnological production and applications of the omega-3 polyunsaturated fatty acid docosahexaenoic acid. Appl. Microbiol. Biotechnol. 64 (2004) 146-153
25. Stoll B.A. n-3 Fatty acids and lipid peroxidation in breast cancer inhibition. Brit. J. Nutr. 87 (2002) 193-198
26. Terry P., Wolk A., Vainio H., and Weiderpass E. Fatty fish consumption lowers the risk of endometrial cancer: a nationwide case-control study in Sweden. Cancer Epidemiol. Biomark. Prev. 11 (2002) 143-145
27. Terry P.D., Rohan T.E., and Wolk A. Intakes of fish and marine fatty acids and the risks of cancers of the breast and prostate and of other hormone-related cancers: a review of the epidemiologic evidence. Am. J. Clin. Nutr. 77 (2003) 532-543
28. Van beelen V.A., Aarts J.M., Reus A., Mooibroek H., Sijtsma L., Bosch D., Rietjens I.M., and Alink G.M. Differential induction of electrophile-responsive element-regulated genes by n-3 and n-6 polyunsaturated fatty acids. FEBS Lett. 580 (2006) 4587-4590
29. Van beelen V.A., Roeleveld J., Mooibroek H., Sijtsma L., Bino R.J., Bosch D., Rietjens I.M., and Alink G.M. A comparative study on the effect of algal and fish oil on viability and cell proliferation of Caco-2 cells. Food Chem. Toxicol. 45 (2006) 716-724
30. Wargovich M.J., Chen C.D., Jimenez A., Steele V.E., Velasco M., Stephens L.C., Price R., Gray K., and Kelloff G.J. Aberrant crypts as a biomarker for colon cancer: evaluation of potential chemopreventive agents in the rat. Cancer Epidemiol. Biomark. Prev. 5 (1996) 355-360
31. Wijnands M.V., Van erk M.J., Doornbos R.P., Krul C.A., and Woutersen R.A. Do aberrant crypt foci have predictive value for the occurrence of colorectal tumours? Potential of gene expression profiling in tumours. Food Chem. Toxicol. 42 (2004) 1629-1639
32. Yla-Herttuala S., Palinski W., Rosenfeld M.E., Parthasarathy S., Carew T.E., Butler S., Witztum J.L., and Steinberg D. Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man. J. Clin. Invest. 84 (1989) 1086-1095
33. Zhang X.M., Stamp D., Minkin S., Medline A., Corpet D.E., Bruce W.R., and Archer M.C. Promotion of aberrant crypt foci and cancer in rat colon by thermolyzed protein. J. Natl. Cancer Inst. 84 (1992) 1026-1030