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Volumn 26, Issue 2, 1997, Pages 343-352

Wholesale hepatocytic differentiation in the rat from ductular oval cells, the progeny of biliary stem cells

Author keywords

acetylaminofluorene; albumin; cytokeratins; liver regeneration; oval cells; vimentin; foetoprotien

Indexed keywords

ALPHA FETOPROTEIN; CYTOCHROME P450; MESSENGER RNA; VIMENTIN;

EID: 0031051487     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(97)80051-7     Document Type: Article
Times cited : (111)

References (52)
  • 1
    • 0023442448 scopus 로고
    • A precusor-product relationship exists between oval cells and hepatocytes in rat liver
    • Evarts RP, Nagy P, Marsden E, Thorgeirsson SS. A precusor-product relationship exists between oval cells and hepatocytes in rat liver. Carcinogenesis. 8:1987;1737-1740.
    • (1987) Carcinogenesis , vol.8 , pp. 1737-1740
    • Evarts, R.P.1    Nagy, P.2    Marsden, E.3    Thorgeirsson, S.S.4
  • 2
    • 0026544368 scopus 로고
    • The stem cells of the liver-a selective review [editorial]
    • Aterman K. The stem cells of the liver-a selective review [editorial]. J Cancer Res Clin Oncol. 118:1992;87-115.
    • (1992) J Cancer Res Clin Oncol , vol.118 , pp. 87-115
    • Aterman, K.1
  • 3
    • 0028206896 scopus 로고
    • Epithelial cell lineages in developing, restoring, and transforming liver: Evidence for the existence of a "differentiation window"
    • Marceau N. Epithelial cell lineages in developing, restoring, and transforming liver: evidence for the existence of a "differentiation window" Gut. 35:1994;294-296.
    • (1994) Gut , vol.35 , pp. 294-296
    • Marceau, N.1
  • 4
    • 0027772191 scopus 로고
    • Hepatic stem cells
    • Thorgeirsson SS. Hepatic stem cells. Am J Pathol. 142:1993;1331-1333.
    • (1993) Am J Pathol , vol.142 , pp. 1331-1333
    • Thorgeirsson, S.S.1
  • 5
    • 0021957640 scopus 로고
    • Differential cytokeratin and alpha-fetoprotein expression in morphologically distinct epithelial cells emerging at the early stage of rat hepatocarcinogenesis
    • Germain L, Goyette R, Marceau N. Differential cytokeratin and alpha-fetoprotein expression in morphologically distinct epithelial cells emerging at the early stage of rat hepatocarcinogenesis. Cancer Res. 45:1985;673-681.
    • (1985) Cancer Res , vol.45 , pp. 673-681
    • Germain, L.1    Goyette, R.2    Marceau, N.3
  • 6
    • 0025934727 scopus 로고
    • Phenotypic characterization of metaplastic intestinal glands and ductural hepatocytes in cholangiofibrotic lesions rapidly induced in the caudate liver lobe of rats treated with furan
    • Elmore LW, Sirica AE. Phenotypic characterization of metaplastic intestinal glands and ductural hepatocytes in cholangiofibrotic lesions rapidly induced in the caudate liver lobe of rats treated with furan. Cancer Res. 51:1991;5752-5759.
    • (1991) Cancer Res , vol.51 , pp. 5752-5759
    • Elmore, L.W.1    Sirica, A.E.2
  • 7
    • 0026469695 scopus 로고
    • Sequential appearance of intestinal mucosal cell types in the right and caudate liver lobes of furan-treated rats
    • Elmore LW, Sirica AE. Sequential appearance of intestinal mucosal cell types in the right and caudate liver lobes of furan-treated rats. Hepatology. 16:1992;1220-1226.
    • (1992) Hepatology , vol.16 , pp. 1220-1226
    • Elmore, L.W.1    Sirica, A.E.2
  • 8
    • 0027476172 scopus 로고
    • "intestinal-type" of adenocarcinoma preferentially induced in right/caudate liver lobes of rats treated with furan
    • Elmore LW, Sirica AE. "Intestinal-type" of adenocarcinoma preferentially induced in right/caudate liver lobes of rats treated with furan. Cancer Res. 53:1993;254-259.
    • (1993) Cancer Res , vol.53 , pp. 254-259
    • Elmore, L.W.1    Sirica, A.E.2
  • 9
    • 0027980830 scopus 로고
    • Ductural hepatocytes. Evidence for a bile ductural cell origin in furan-treated rats
    • Sirica AE, Gainey TW, Mumaw VR. Ductural hepatocytes. Evidence for a bile ductural cell origin in furan-treated rats. Am J Pathol. 145:1994;375-383.
    • (1994) Am J Pathol , vol.145 , pp. 375-383
    • Sirica, A.E.1    Gainey, T.W.2    Mumaw, V.R.3
  • 10
    • 0028122926 scopus 로고
    • Origin and fate of oval cells in dipin-induced hepatocarcinogenesis in the mouse
    • Factor VM, Radaeva SA, Thorgeirsson SS. Origin and fate of oval cells in dipin-induced hepatocarcinogenesis in the mouse. Am J Pathol. 145:1994;409-422.
    • (1994) Am J Pathol , vol.145 , pp. 409-422
    • Factor, V.M.1    Radaeva, S.A.2    Thorgeirsson, S.S.3
  • 11
    • 0030053365 scopus 로고    scopus 로고
    • Proliferation, apoptosis, and induction of hepatic transcription factors are characteristics of the early response of biliary epithelial (oval) cells to chemical carcinogens
    • Bisgaard HC, Nagy P, Santoni-Rigiu E, Thorgeirsson SS. Proliferation, apoptosis, and induction of hepatic transcription factors are characteristics of the early response of biliary epithelial (oval) cells to chemical carcinogens. Hepatology. 23:1996;62-70.
    • (1996) Hepatology , vol.23 , pp. 62-70
    • Bisgaard, H.C.1    Nagy, P.2    Santoni-Rigiu, E.3    Thorgeirsson, S.S.4
  • 12
    • 0021982962 scopus 로고
    • Connection of ductlike structures induced by a chemical hepatocarginogen to portal bile ducts in the rat liver detected by injection of bile ducts with a pigmented barium gelatin medium
    • Dunsford HA, Maset R, Salman J, Sell S. Connection of ductlike structures induced by a chemical hepatocarginogen to portal bile ducts in the rat liver detected by injection of bile ducts with a pigmented barium gelatin medium. Am J Pathol. 118:1985;218-224.
    • (1985) Am J Pathol , vol.118 , pp. 218-224
    • Dunsford, H.A.1    Maset, R.2    Salman, J.3    Sell, S.4
  • 13
    • 0026758703 scopus 로고
    • Distribution of albumin and alpha-fetoprotein mRNAs in normal hyperplastic, and preneoplastic rat liver
    • Alpini G, Aragona E, Dabeva M, Salvi R, Shafritz DA, Tavolini N. Distribution of albumin and alpha-fetoprotein mRNAs in normal hyperplastic, and preneoplastic rat liver. Am J Pathol. 141:1992;623-632.
    • (1992) Am J Pathol , vol.141 , pp. 623-632
    • Alpini, G.1    Aragona, E.2    Dabeva, M.3    Salvi, R.4    Shafritz, D.A.5    Tavolini, N.6
  • 14
    • 0026523601 scopus 로고
    • Histogenesis of bile duct-like cells proliferating during ethionine hepatocarcinogenesis. Evidence for a biliary epithelial nature of oval cells
    • Lenzi R, Liu MH, Tarsetti F, Slott PA, Alpin G, Zhai WR, Paronetto F, Lenzen R, Tavoloni N. Histogenesis of bile duct-like cells proliferating during ethionine hepatocarcinogenesis. Evidence for a biliary epithelial nature of oval cells. Lab Invest. 66:1992;390-402.
    • (1992) Lab Invest , vol.66 , pp. 390-402
    • Lenzi, R.1    Liu, M.H.2    Tarsetti, F.3    Slott, P.A.4    Alpin, G.5    Zhai, W.R.6    Paronetto, F.7    Lenzen, R.8    Tavoloni, N.9
  • 15
    • 0020625972 scopus 로고
    • Comparison of oval cells induced in rat liver by feeding N-2-fluorenylacetamide in a choline-devoid diet and bile duct cells induced by feeding 4,4′-diaminodiphenylmethane
    • Sell S. Comparison of oval cells induced in rat liver by feeding N-2-fluorenylacetamide in a choline-devoid diet and bile duct cells induced by feeding 4,4′-diaminodiphenylmethane. Cancer Res. 43:1983;1761-1767.
    • (1983) Cancer Res , vol.43 , pp. 1761-1767
    • Sell, S.1
  • 16
    • 0019519660 scopus 로고
    • Autoradiography of "oval cells" appearing rapidly in the livers of rats fed N-2-fluorenylacetamide in a choline devoid diet
    • Sell S, Osborn K, Leffert HL. Autoradiography of "oval cells" appearing rapidly in the livers of rats fed N-2-fluorenylacetamide in a choline devoid diet. Carcinogenesis. 2:1981;7-14.
    • (1981) Carcinogenesis , vol.2 , pp. 7-14
    • Sell, S.1    Osborn, K.2    Leffert, H.L.3
  • 17
    • 0021353535 scopus 로고
    • Light- And electron-microscopic autoradiographic analysis of proliferating cells during the early stages of chemical hepatocarcinogenesis in the rat induced by feeding N-2-fluorenylacetamide in a choline-deficient diet
    • Sell S, Salman J. Light- and electron-microscopic autoradiographic analysis of proliferating cells during the early stages of chemical hepatocarcinogenesis in the rat induced by feeding N-2-fluorenylacetamide in a choline-deficient diet. Am J Pathol. 114:1984;287-300.
    • (1984) Am J Pathol , vol.114 , pp. 287-300
    • Sell, S.1    Salman, J.2
  • 18
    • 0028587815 scopus 로고
    • Differentiation of oval cells into duct-like cells in preneoplastic liver of rats placed on a choline-deficient diet supplemented with ethionine
    • Tee LB, Kirilak Y, Huang WH, Morgan RH, Yeoh GC. Differentiation of oval cells into duct-like cells in preneoplastic liver of rats placed on a choline-deficient diet supplemented with ethionine. Carcinogenesis. 15:1994;2747-2756.
    • (1994) Carcinogenesis , vol.15 , pp. 2747-2756
    • Tee, L.B.1    Kirilak, Y.2    Huang, W.H.3    Morgan, R.H.4    Yeoh, G.C.5
  • 19
    • 0027240102 scopus 로고
    • Liver carcinogenesis associated with feeding of ethionine in a choline-free diet: Evidence against a role of oval cells in the emergence of hepatocellular carcinoma
    • Tarsetti F, Lenzi R, Salvi R, Schuler E, Rijhsingani K, Lenzen R, Tavoloni N. Liver carcinogenesis associated with feeding of ethionine in a choline-free diet: evidence against a role of oval cells in the emergence of hepatocellular carcinoma. Hepatology. 18:1993;596-603.
    • (1993) Hepatology , vol.18 , pp. 596-603
    • Tarsetti, F.1    Lenzi, R.2    Salvi, R.3    Schuler, E.4    Rijhsingani, K.5    Lenzen, R.6    Tavoloni, N.7
  • 20
    • 0029034469 scopus 로고
    • Participation of small intraportal stem cells in the restitutive response of the liver to periportal necrosis induced by allyl alcohol
    • Yavorkovsky L, Lai E, Ilic Z, Sell S. Participation of small intraportal stem cells in the restitutive response of the liver to periportal necrosis induced by allyl alcohol. Hepatology. 21:1995;1702-1712.
    • (1995) Hepatology , vol.21 , pp. 1702-1712
    • Yavorkovsky, L.1    Lai, E.2    Ilic, Z.3    Sell, S.4
  • 21
    • 0030053366 scopus 로고    scopus 로고
    • Appearance of oval cells in the liver of rats after long-term exposure to ethanol
    • Smith PGJ, Tee LBG, Yeoh GCT. Appearance of oval cells in the liver of rats after long-term exposure to ethanol. Hepatology. 23:1996;145-154.
    • (1996) Hepatology , vol.23 , pp. 145-154
    • Smith, P.G.J.1    Tee, L.B.G.2    Yeoh, G.C.T.3
  • 22
    • 0027732935 scopus 로고
    • Activation, proliferation, and differentiation of progenitor cells into hepatocytes in the D-galactosamine model of liver regeneration
    • Dabeva MD, Shafritz DA. Activation, proliferation, and differentiation of progenitor cells into hepatocytes in the D-galactosamine model of liver regeneration. Am J Pathol. 143:1993;1606-1620.
    • (1993) Am J Pathol , vol.143 , pp. 1606-1620
    • Dabeva, M.D.1    Shafritz, D.A.2
  • 24
    • 0025873457 scopus 로고
    • Oval cell proliferation and the origin of small hepatocytes in liver injury induced by D-galactosamine
    • Lemire JM, Shiojiri N, Fausto N. Oval cell proliferation and the origin of small hepatocytes in liver injury induced by D-galactosamine. Am J Pathol. 139:1991;535-552.
    • (1991) Am J Pathol , vol.139 , pp. 535-552
    • Lemire, J.M.1    Shiojiri, N.2    Fausto, N.3
  • 25
    • 0027769557 scopus 로고
    • Expression of hepatocyte growth factor mRNA during oval cell activation in the rat liver
    • Alison MR, Poulsom R, Jeffery R, Anilkumar TV, Jagoe R, Sarraf CE. Expression of hepatocyte growth factor mRNA during oval cell activation in the rat liver. J Pathol. 171:1993;291-299.
    • (1993) J Pathol , vol.171 , pp. 291-299
    • Alison, M.R.1    Poulsom, R.2    Jeffery, R.3    Anilkumar, T.V.4    Jagoe, R.5    Sarraf, C.E.6
  • 26
    • 0029935079 scopus 로고    scopus 로고
    • Liver damage in the rat induces hepatocyte stem cells from biliary epithelial cells
    • Alison MR, Golding M, Sarraf CE, Edwards RJ, Lalani EN. Liver damage in the rat induces hepatocyte stem cells from biliary epithelial cells. Gastroenterology. 110:1996;1182-1190.
    • (1996) Gastroenterology , vol.110 , pp. 1182-1190
    • Alison, M.R.1    Golding, M.2    Sarraf, C.E.3    Edwards, R.J.4    Lalani, E.N.5
  • 27
    • 0028239374 scopus 로고
    • Modulation of keratin 14 and alpha-fetoprotein expression during hepatic oval cell proliferation and liver regeneration
    • Bisgaard HC, Nagy P, Ton PT, Hu Z, Thorgeirsson SS. Modulation of keratin 14 and alpha-fetoprotein expression during hepatic oval cell proliferation and liver regeneration. J Cell Physiol. 159:1994;475-484.
    • (1994) J Cell Physiol , vol.159 , pp. 475-484
    • Bisgaard, H.C.1    Nagy, P.2    Ton, P.T.3    Hu, Z.4    Thorgeirsson, S.S.5
  • 29
    • 0026596801 scopus 로고
    • Expression of transforming growth factor-alpha in regenerating liver and during hepatic differentiation
    • Evarts RP, Nakatsukasa H, Marsden ER, Hu Z, Thorgeirsson SS. Expression of transforming growth factor-alpha in regenerating liver and during hepatic differentiation. Mol Carcinog. 5:1992;25-31.
    • (1992) Mol Carcinog , vol.5 , pp. 25-31
    • Evarts, R.P.1    Nakatsukasa, H.2    Marsden, E.R.3    Hu, Z.4    Thorgeirsson, S.S.5
  • 30
    • 0028276073 scopus 로고
    • Expression of stem cell factor and its receptor, c-kit, during liver regeneration from putative stem cells in adult rat
    • Fujio K, Evarts RP, Hu Z, Marsden ER, Thorgeirsson SS. Expression of stem cell factor and its receptor, c-kit, during liver regeneration from putative stem cells in adult rat. Lab Invest. 70:1994;511-516.
    • (1994) Lab Invest , vol.70 , pp. 511-516
    • Fujio, K.1    Evarts, R.P.2    Hu, Z.3    Marsden, E.R.4    Thorgeirsson, S.S.5
  • 32
    • 0021796888 scopus 로고
    • Intestinal metaplasia as a common option of oval cells in relation to cholangiofibrosis in liver of rats exposed to 2-acetylaminofluorene
    • Tatematsu M, Kaku T, Medline A, Farber E. Intestinal metaplasia as a common option of oval cells in relation to cholangiofibrosis in liver of rats exposed to 2-acetylaminofluorene. Lab Invest. 52:1985;354-362.
    • (1985) Lab Invest , vol.52 , pp. 354-362
    • Tatematsu, M.1    Kaku, T.2    Medline, A.3    Farber, E.4
  • 33
    • 0027999434 scopus 로고
    • Cell behaviour in the acetylaminofluorene-treated regenerating rat liver. Light and electron microscopic observations
    • Sarraf CE, Lalani E-N, Golding M, Anilkumar TV, Poulsom R, Alison MR. Cell behaviour in the acetylaminofluorene-treated regenerating rat liver. Light and electron microscopic observations. Am J Pathol. 145:1994;1114-1126.
    • (1994) Am J Pathol , vol.145 , pp. 1114-1126
    • Sarraf, C.E.1    Lalani E-N2    Golding, M.3    Anilkumar, T.V.4    Poulsom, R.5    Alison, M.R.6
  • 35
    • 0025132658 scopus 로고
    • Lipid peroxidation and protein thiol depletion are not involved in the cytotoxicity of N-hydroxy-2-acetylaminofluorene in isolated rat hepatocytes
    • Kroese ED, Bannenberg G, Dogterom P, Noach AB, Nagelkerke JF, Meerman JH. Lipid peroxidation and protein thiol depletion are not involved in the cytotoxicity of N-hydroxy-2-acetylaminofluorene in isolated rat hepatocytes. Biochem Pharmacol. 40:1990;1885-1892.
    • (1990) Biochem Pharmacol , vol.40 , pp. 1885-1892
    • Kroese, E.D.1    Bannenberg, G.2    Dogterom, P.3    Noach, A.B.4    Nagelkerke, J.F.5    Meerman, J.H.6
  • 36
    • 0024581801 scopus 로고
    • Enzyme profile of rat bile ductural epithelial cells in reference to the resistant phenotype in hepatocarcinogenesis
    • Mathis GA, Walls SA, D'Amico P, Gengo TF, Sirica AE. Enzyme profile of rat bile ductural epithelial cells in reference to the resistant phenotype in hepatocarcinogenesis. Hepatology. 9:1989;477-485.
    • (1989) Hepatology , vol.9 , pp. 477-485
    • Mathis, G.A.1    Walls, S.A.2    D'Amico, P.3    Gengo, T.F.4    Sirica, A.E.5
  • 37
    • 0025343853 scopus 로고
    • Isolation, culture, and transplantation of intrahepatic biliary epithelial cells and oval cells
    • Sirica AE, Mathis GA, Sano N, Elmore LW. Isolation, culture, and transplantation of intrahepatic biliary epithelial cells and oval cells. Pathobiology. 58:1990;44-64.
    • (1990) Pathobiology , vol.58 , pp. 44-64
    • Sirica, A.E.1    Mathis, G.A.2    Sano, N.3    Elmore, L.W.4
  • 38
    • 0020672333 scopus 로고
    • Metabolic properties of isolated rat liver cell preparations enriched in epithelial cells other than hepatocytes
    • Ledda GM, Sells MA, Yokoyama S, Lombardi B. Metabolic properties of isolated rat liver cell preparations enriched in epithelial cells other than hepatocytes. Int J Cancer. 31:1983;231-237.
    • (1983) Int J Cancer , vol.31 , pp. 231-237
    • Ledda, G.M.1    Sells, M.A.2    Yokoyama, S.3    Lombardi, B.4
  • 39
    • 0028291370 scopus 로고
    • Expression of hepatic transcription factors during liver development and oval cell differentiation
    • Nagy P, Bisgaard HC, Thorgeirsson SS. Expression of hepatic transcription factors during liver development and oval cell differentiation. J Cell Biol. 126:1994;223-233.
    • (1994) J Cell Biol , vol.126 , pp. 223-233
    • Nagy, P.1    Bisgaard, H.C.2    Thorgeirsson, S.S.3
  • 40
    • 0023205866 scopus 로고
    • In situ hybridization studies on expression of albumin and alpha-fetoprotein during the early stage of neoplastic transformation in rat liver
    • Evarts RP, Nagy P, Marsden E, Thorgeirsson SS. In situ hybridization studies on expression of albumin and alpha-fetoprotein during the early stage of neoplastic transformation in rat liver. Cancer Res. 47:1987;5469-5475.
    • (1987) Cancer Res , vol.47 , pp. 5469-5475
    • Evarts, R.P.1    Nagy, P.2    Marsden, E.3    Thorgeirsson, S.S.4
  • 42
    • 0028958095 scopus 로고
    • The resistant hepatocyte model of carcinogenesis in the rat: The apparent independent development of oval cell proliferation and early nodules
    • Anilkumar TV, Golding M, Edwards RJ, Lalani E-N, Sarraf CE, Alison MR. The resistant hepatocyte model of carcinogenesis in the rat: the apparent independent development of oval cell proliferation and early nodules. Carcinogenesis. 16:1995;845-853.
    • (1995) Carcinogenesis , vol.16 , pp. 845-853
    • Anilkumar, T.V.1    Golding, M.2    Edwards, R.J.3    Lalani E-N4    Sarraf, C.E.5    Alison, M.R.6
  • 44
    • 0025642786 scopus 로고
    • Malignant cells of epithelial phenotype limited to thoracic lymph nodes
    • Gould VE, Warren WH, Faber LP, Kuhn C, Franke WW. Malignant cells of epithelial phenotype limited to thoracic lymph nodes. Eur J Cancer. 26:1990;1121-1126.
    • (1990) Eur J Cancer , vol.26 , pp. 1121-1126
    • Gould, V.E.1    Warren, W.H.2    Faber, L.P.3    Kuhn, C.4    Franke, W.W.5
  • 45
    • 0030052431 scopus 로고    scopus 로고
    • Experimental coexpression of vimentin and keratin intermediate filaments in human melanoma cells augments motility
    • Chu YW, Seftor EA, Romer LH, Hendrix MJC. Experimental coexpression of vimentin and keratin intermediate filaments in human melanoma cells augments motility. Am J Pathol. 148-:1996;63-69.
    • (1996) Am J Pathol , vol.148 , pp. 63-69
    • Chu, Y.W.1    Seftor, E.A.2    Romer, L.H.3    Hendrix, M.J.C.4
  • 46
    • 0028961443 scopus 로고
    • Epithelial-mesenchymal transition in cultured neonatal hepatocytes
    • Pagan R, Llobera M, Vilaro S. Epithelial-mesenchymal transition in cultured neonatal hepatocytes. Hepatology. 21:1995;820-831.
    • (1995) Hepatology , vol.21 , pp. 820-831
    • Pagan, R.1    Llobera, M.2    Vilaro, S.3
  • 48
    • 0025944323 scopus 로고
    • Multiple alpha-fetoprotein RNAs in adult rat liver: Cell type-specific expression and differential regulation
    • Lemire JM, Fausto N. Multiple alpha-fetoprotein RNAs in adult rat liver: cell type-specific expression and differential regulation. Cancer Res. 51:1991;4656-4664.
    • (1991) Cancer Res , vol.51 , pp. 4656-4664
    • Lemire, J.M.1    Fausto, N.2
  • 49
    • 0026447566 scopus 로고
    • Occurrence of oval-type cells in hepatitis B virus-associated human hepatocarcinogenesis
    • Hsia CC, Evarts RP, Nakatsukasa H, Marsden ER, Thorgeirsson SS. Occurrence of oval-type cells in hepatitis B virus-associated human hepatocarcinogenesis. Hepatology. 16:1992;1327-1333.
    • (1992) Hepatology , vol.16 , pp. 1327-1333
    • Hsia, C.C.1    Evarts, R.P.2    Nakatsukasa, H.3    Marsden, E.R.4    Thorgeirsson, S.S.5
  • 50
    • 0028936169 scopus 로고
    • Alpha-fetoprotein binding proteins: Implications for transmembrane passage and subcellular localization
    • Mizejewski GJ. Alpha-fetoprotein binding proteins: implications for transmembrane passage and subcellular localization. Life Sci. 56:1995;1-9.
    • (1995) Life Sci , vol.56 , pp. 1-9
    • Mizejewski, G.J.1
  • 51
    • 0030031136 scopus 로고    scopus 로고
    • Allelic loss on chromosomes 4q and 16q in hepatocellular carcinoma: Association with elevated α-fetoprotein production
    • Yeh SH, Chen PJ, Lai MY, Chen DS. Allelic loss on chromosomes 4q and 16q in hepatocellular carcinoma: association with elevated α-fetoprotein production. Gastroenterology. 110:1996;184-192.
    • (1996) Gastroenterology , vol.110 , pp. 184-192
    • Yeh, S.H.1    Chen, P.J.2    Lai, M.Y.3    Chen, D.S.4
  • 52
    • 0027253639 scopus 로고
    • Isolation biochemical characterization, long-term culture, and pheno-type modulation of oval cells from carcinogen-fed rats
    • Pack R, Heck R, Dienes HP, Oesch F, Steinberg P. Isolation biochemical characterization, long-term culture, and pheno-type modulation of oval cells from carcinogen-fed rats. Exp Cell Res. 204:1993;198-209.
    • (1993) Exp Cell Res , vol.204 , pp. 198-209
    • Pack, R.1    Heck, R.2    Dienes, H.P.3    Oesch, F.4    Steinberg, P.5


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