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Volumn 86, Issue 10, 2008, Pages 1452-1462

Suppressive efficacy and proliferative capacity of human regulatory t cells in allogeneic and xenogeneic responses

Author keywords

Human; Mixed lymphocyte reaction; Pig; Regulatory T cells; Xenotransplantation.

Indexed keywords

ALPHA 1,3 GALACTOSYLTRANSFERASE; CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; TRANSCRIPTION FACTOR FOXP3; GALACTOSYLTRANSFERASE; INTERLEUKIN 2 RECEPTOR ALPHA; LEUKOCYTE ANTIGEN;

EID: 58149330240     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e318188acb0     Document Type: Article
Times cited : (51)

References (68)
  • 1
    • 0042157265 scopus 로고    scopus 로고
    • Clinical xenotransplantion - How close are we?
    • Cooper DK. Clinical xenotransplantion - How close are we? Lancet 2003; 362: 557.
    • (2003) Lancet , vol.362 , pp. 557
    • Cooper, D.K.1
  • 2
    • 0347367029 scopus 로고    scopus 로고
    • Production of alpha 1,3galactosyltransferase-deficient pigs
    • Phelps CJ, Koike C, Vaught TD, et al. Production of alpha 1,3galactosyltransferase-deficient pigs. Science 2003; 299: 411.
    • (2003) Science , vol.299 , pp. 411
    • Phelps, C.J.1    Koike, C.2    Vaught, T.D.3
  • 3
    • 2442567900 scopus 로고    scopus 로고
    • Production of alpha-1,3 galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations
    • Kolber-Simonds D, Lai L, Watt SR, et al. Production of alpha-1,3 galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations. Proc Natl Acad Sci USA 2004; 101: 7335.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 7335
    • Kolber-Simonds, D.1    Lai, L.2    Watt, S.R.3
  • 4
    • 14644408009 scopus 로고    scopus 로고
    • How strong is the T cell response in the pigto-primate model?
    • Buhler LH, Cooper DK. How strong is the T cell response in the pigto-primate model? Xenotransplantation 2005; 12: 85.
    • (2005) Xenotransplantation , vol.12 , pp. 85
    • Buhler, L.H.1    Cooper, D.K.2
  • 5
    • 0028220009 scopus 로고
    • Cell-mediated xenoresponses: Strong or weak?
    • Auchincloss H Jr. Cell-mediated xenoresponses: Strong or weak? Clin Transplant 1994; 8 (2 Pt 2): 155.
    • (1994) Clin Transplant , vol.8 , Issue.2 PART 2 , pp. 155
    • Auchincloss Jr., H.1
  • 7
    • 0028889431 scopus 로고
    • Human anti-porcine xenogeneic T cell response. Evidence for allelic specificity of mixed leukocyte reaction and for both direct and indirect pathways of recognition
    • Yamada K, Sachs DH, DerSimonian H. Human anti-porcine xenogeneic T cell response. Evidence for allelic specificity of mixed leukocyte reaction and for both direct and indirect pathways of recognition. J Immunol 1995; 155: 5249.
    • (1995) J Immunol , vol.155 , pp. 5249
    • Yamada, K.1    Sachs, D.H.2    DerSimonian, H.3
  • 8
    • 0012573960 scopus 로고    scopus 로고
    • Immunobiology of xenotransplantation
    • Platt JL. Immunobiology of xenotransplantation. Transpl Int 2000; 13(suppl 1): S7.
    • (2000) Transpl Int , vol.13 , Issue.SUPPL. 1
    • Platt, J.L.1
  • 9
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 2003; 3: 199.
    • (2003) Nat Rev Immunol , vol.3 , pp. 199
    • Wood, K.J.1    Sakaguchi, S.2
  • 10
    • 1242295283 scopus 로고    scopus 로고
    • Regulatory T cells and organ transplantation
    • Waldmann H, Graca L, Cobbold S, et al. Regulatory T cells and organ transplantation. Semin Immunol 2004; 16: 119.
    • (2004) Semin Immunol , vol.16 , pp. 119
    • Waldmann, H.1    Graca, L.2    Cobbold, S.3
  • 11
    • 22844451603 scopus 로고    scopus 로고
    • Human CD4+CD25+ regulatory T cells sup- press anti-porcine xenogeneic responses
    • Porter CM, Bloom ET. Human CD4+CD25+ regulatory T cells sup- press anti-porcine xenogeneic responses. Am J Transplant 2005; 5: 2052.
    • (2005) Am J Transplant , vol.5 , pp. 2052
    • Porter, C.M.1    Bloom, E.T.2
  • 12
    • 0031437624 scopus 로고    scopus 로고
    • Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response
    • Wells AD, Gudmundsdottir H, Turka LA. Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response. J Clin Invest 1997; 100: 3173.
    • (1997) J Clin Invest , vol.100 , pp. 3173
    • Wells, A.D.1    Gudmundsdottir, H.2    Turka, L.A.3
  • 13
    • 0035076855 scopus 로고    scopus 로고
    • CFSE dye dilution mixed lymphocyte reactions quantify donor-specific alloreactive precursors in non-human primate cardiac graft rejection
    • Nitta Y, Nelson K, Andrews RG, et al. CFSE dye dilution mixed lymphocyte reactions quantify donor-specific alloreactive precursors in non-human primate cardiac graft rejection. Transplant Proc 2001; 33: 326.
    • (2001) Transplant Proc , vol.33 , pp. 326
    • Nitta, Y.1    Nelson, K.2    Andrews, R.G.3
  • 14
    • 20444500934 scopus 로고    scopus 로고
    • Liver sinusoidal endothelial cells contribute to alloreactive T-cell tolerance induced by portal venous injection of donor splenocytes
    • Tokita D, Ohdan H, Onoe T, et al. Liver sinusoidal endothelial cells contribute to alloreactive T-cell tolerance induced by portal venous injection of donor splenocytes. Transpl Int 2005; 18: 237.
    • (2005) Transpl Int , vol.18 , pp. 237
    • Tokita, D.1    Ohdan, H.2    Onoe, T.3
  • 15
    • 0035185411 scopus 로고    scopus 로고
    • Control of T-cell activation by CD4+ CD25+ suppressor T cells
    • Shevach EM, McHugh RS, Piccirillo CA, et al. Control of T-cell activation by CD4+ CD25+ suppressor T cells. ImmunolRev 2001; 182:58.
    • (2001) ImmunolRev , vol.182 , pp. 58
    • Shevach, E.M.1    McHugh, R.S.2    Piccirillo, C.A.3
  • 16
    • 12344254024 scopus 로고    scopus 로고
    • Regulating the immune system: The induction of regulatory T cells in the periphery
    • Buckner JH, Ziegler SF. Regulating the immune system: The induction of regulatory T cells in the periphery. Arthritis Res Ther 2004; 6: 215.
    • (2004) Arthritis Res Ther , vol.6 , pp. 215
    • Buckner, J.H.1    Ziegler, S.F.2
  • 17
    • 33750008921 scopus 로고    scopus 로고
    • Regulatory T cells and transplantation tolerance
    • Jiang S, Lechler RI, He XS, et al. Regulatory T cells and transplantation tolerance. Hum Immunol 2006; 67: 765.
    • (2006) Hum Immunol , vol.67 , pp. 765
    • Jiang, S.1    Lechler, R.I.2    He, X.S.3
  • 18
    • 33746324214 scopus 로고    scopus 로고
    • The role of regulatory T cells in alloantigen tolerance
    • Aluvihare VR, Betz AG. The role of regulatory T cells in alloantigen tolerance. Immunol Rev 2006; 212: 330.
    • (2006) Immunol Rev , vol.212 , pp. 330
    • Aluvihare, V.R.1    Betz, A.G.2
  • 19
    • 33748598236 scopus 로고    scopus 로고
    • Regulatory T-cells in the control of immunological diseases
    • Franzke A, Hunger JK, Dittmar KE, et al. Regulatory T-cells in the control of immunological diseases. Ann Hematol 2006; 85: 747.
    • (2006) Ann Hematol , vol.85 , pp. 747
    • Franzke, A.1    Hunger, J.K.2    Dittmar, K.E.3
  • 20
    • 33646168597 scopus 로고    scopus 로고
    • Ziegler SF. FOXP3: Ofmice and men. Annu Rev Immunol2006; 24:209.
    • Ziegler SF. FOXP3: Ofmice and men. Annu Rev Immunol2006; 24:209.
  • 21
    • 0035413350 scopus 로고    scopus 로고
    • CD4+CD25high regulatory cells in human peripheral blood
    • Baecher-Allan C, Brown JA, Freeman GJ, et al. CD4+CD25high regulatory cells in human peripheral blood. J Immunol 2001; 167: 1245.
    • (2001) J Immunol , vol.167 , pp. 1245
    • Baecher-Allan, C.1    Brown, J.A.2    Freeman, G.J.3
  • 22
    • 0035167967 scopus 로고    scopus 로고
    • Bennett CL, Christie J, Ramsdell F, et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001; 27: 20.
    • Bennett CL, Christie J, Ramsdell F, et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001; 27: 20.
  • 23
    • 0346969978 scopus 로고    scopus 로고
    • Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25-T cells
    • Walker MR, Kasprowicz DJ, Gersuk VH, et al. Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25-T cells. J Clin Invest 2003; 112: 1437.
    • (2003) J Clin Invest , vol.112 , pp. 1437
    • Walker, M.R.1    Kasprowicz, D.J.2    Gersuk, V.H.3
  • 24
    • 19944369378 scopus 로고    scopus 로고
    • Expression of FOXP3 mRNA is not confined to CD4+CD25 + T regulatory cells in humans
    • Morgan ME, van Bilsen JH, Bakker AM, et al. Expression of FOXP3 mRNA is not confined to CD4+CD25 + T regulatory cells in humans. Hum Immunol 2005; 66: 13.
    • (2005) Hum Immunol , vol.66 , pp. 13
    • Morgan, M.E.1    van Bilsen, J.H.2    Bakker, A.M.3
  • 25
    • 27644449311 scopus 로고    scopus 로고
    • Allan SE, Passerini L, Bacchetta R, et al. The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.JClin Invest 2005; 115:3276.
    • Allan SE, Passerini L, Bacchetta R, et al. The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.JClin Invest 2005; 115:3276.
  • 26
    • 33646052605 scopus 로고    scopus 로고
    • Functional study of CD4+CD25+ regulatory T cells in health and autoimmune hepatitis
    • Longhi MS, Hussain MJ, Mitry RR, et al. Functional study of CD4+CD25+ regulatory T cells in health and autoimmune hepatitis. J Immunol 2006; 176: 4484.
    • (2006) J Immunol , vol.176 , pp. 4484
    • Longhi, M.S.1    Hussain, M.J.2    Mitry, R.R.3
  • 27
    • 34247895580 scopus 로고    scopus 로고
    • Defining target antigens for CD25 + FOXP3 + IFN-gamma- regulatory T cells in chronic hepatitis C virus infection
    • Li S, Jones KL, Woollard DJ, et al. Defining target antigens for CD25 + FOXP3 + IFN-gamma- regulatory T cells in chronic hepatitis C virus infection. Immunol Cell Biol 2007; 85: 197.
    • (2007) Immunol Cell Biol , vol.85 , pp. 197
    • Li, S.1    Jones, K.L.2    Woollard, D.J.3
  • 28
    • 29144436254 scopus 로고    scopus 로고
    • alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months
    • Tseng YL, KuwakiK, DorFJ, etal. alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months. Transplantation 2005; 80: 1493.
    • (2005) Transplantation , vol.80 , pp. 1493
    • Tseng, Y.L.1    Kuwaki, K.2    Dor, F.J.3
  • 29
    • 0036766651 scopus 로고    scopus 로고
    • Clinical xenotransplantation: Pigs might fly?
    • Dorling A. Clinical xenotransplantation: Pigs might fly? Am J Transplant 2002; 2: 695.
    • (2002) Am J Transplant , vol.2 , pp. 695
    • Dorling, A.1
  • 30
    • 0027506406 scopus 로고
    • The human antiporcine cellular repertoire. In vitro studies of acquired and innate cellular responsiveness
    • Kirk AD, Li RA, Kinch MS, et al. The human antiporcine cellular repertoire. In vitro studies of acquired and innate cellular responsiveness. Transplantation 1993; 55: 924.
    • (1993) Transplantation , vol.55 , pp. 924
    • Kirk, A.D.1    Li, R.A.2    Kinch, M.S.3
  • 32
    • 0030051044 scopus 로고    scopus 로고
    • Detection of primary direct and indirect human anti-porcine T cell responses using a porcine dendritic cell population
    • Dorling A, Lombardi G, Binns R, et al. Detection of primary direct and indirect human anti-porcine T cell responses using a porcine dendritic cell population. Eur J Immunol 1996; 26: 1378.
    • (1996) Eur J Immunol , vol.26 , pp. 1378
    • Dorling, A.1    Lombardi, G.2    Binns, R.3
  • 33
    • 0032428076 scopus 로고    scopus 로고
    • T cell-mediated xenograft rejection: Specific tolerance is probably required for long term xenograft survival
    • Dorling A, Lechler RI. T cell-mediated xenograft rejection: Specific tolerance is probably required for long term xenograft survival. Xenotransplantation 1998; 5: 234.
    • (1998) Xenotransplantation , vol.5 , pp. 234
    • Dorling, A.1    Lechler, R.I.2
  • 34
    • 0037559159 scopus 로고    scopus 로고
    • Analysis of human CD4 T lymphocyte proliferation induced by porcine lymphoblastoid B cell lines
    • Bonenfant C, Vallee I, Sun J, et al. Analysis of human CD4 T lymphocyte proliferation induced by porcine lymphoblastoid B cell lines. Xenotransplantation 2003; 10: 107.
    • (2003) Xenotransplantation , vol.10 , pp. 107
    • Bonenfant, C.1    Vallee, I.2    Sun, J.3
  • 35
    • 0028878987 scopus 로고
    • Direct recognition of SLA-and HLA-like class II antigens on porcine endothelium by human T cells results in T cell activation and release of interleukin-2
    • Bravery CA, Batten P, Yacoub MH, et al. Direct recognition of SLA-and HLA-like class II antigens on porcine endothelium by human T cells results in T cell activation and release of interleukin-2. Transplantation 1995; 60: 1024.
    • (1995) Transplantation , vol.60 , pp. 1024
    • Bravery, C.A.1    Batten, P.2    Yacoub, M.H.3
  • 36
    • 0029984713 scopus 로고    scopus 로고
    • Significant primary indirect human T-cell anti-pig xenoresponses observed using immature porcine dendritic cells and SLA-class II-negative endothelial cells
    • Dorling A, Binns R, Lechler RI. Significant primary indirect human T-cell anti-pig xenoresponses observed using immature porcine dendritic cells and SLA-class II-negative endothelial cells. Transplant Proc 1996; 28: 654.
    • (1996) Transplant Proc , vol.28 , pp. 654
    • Dorling, A.1    Binns, R.2    Lechler, R.I.3
  • 37
    • 0032529622 scopus 로고    scopus 로고
    • Human T lymphocyte proliferative response to resting porcine endothelial cells results from an HLA-restricted, IL-10-sensitive, indirect presentation pathway but also depends on endothelial-specific costimulatory factors
    • Vallee I, Guillaumin JM, Thibault G, et al. Human T lymphocyte proliferative response to resting porcine endothelial cells results from an HLA-restricted, IL-10-sensitive, indirect presentation pathway but also depends on endothelial-specific costimulatory factors. J Immunol 1998; 161: 1652.
    • (1998) J Immunol , vol.161 , pp. 1652
    • Vallee, I.1    Guillaumin, J.M.2    Thibault, G.3
  • 38
    • 4444231191 scopus 로고    scopus 로고
    • New spectrum of allorecognition pathways: Implications for graft rejection and transplantation tolerance
    • Jiang S, Herrera O, Lechler RI. New spectrum of allorecognition pathways: Implications for graft rejection and transplantation tolerance. Curr Opin Immunol 2004; 16: 550.
    • (2004) Curr Opin Immunol , vol.16 , pp. 550
    • Jiang, S.1    Herrera, O.2    Lechler, R.I.3
  • 39
    • 0028406899 scopus 로고
    • Porcine aortic endothelial cells activate human T cells: Direct presentation of MHC antigens and costimulation by ligands for human CD2 and CD28
    • Murray AG, Khodadoust MM, Pober JS, et al. Porcine aortic endothelial cells activate human T cells: Direct presentation of MHC antigens and costimulation by ligands for human CD2 and CD28. Immunity 1994; 1: 57.
    • (1994) Immunity , vol.1 , pp. 57
    • Murray, A.G.1    Khodadoust, M.M.2    Pober, J.S.3
  • 40
    • 0028321443 scopus 로고
    • Evidence that activation of human T cells by porcine endothelium involves direct recognition of porcine SLA and costimulation by porcine ligands for LFA-1 and CD2
    • Rollins SA, Kennedy SP, Chodera AJ, et al. Evidence that activation of human T cells by porcine endothelium involves direct recognition of porcine SLA and costimulation by porcine ligands for LFA-1 and CD2. Transplantation 1994; 57: 1709.
    • (1994) Transplantation , vol.57 , pp. 1709
    • Rollins, S.A.1    Kennedy, S.P.2    Chodera, A.J.3
  • 41
    • 0034721098 scopus 로고    scopus 로고
    • Cyclosporine inhibits class II major histocompatibility antigen presentation by xenogeneic endothelial cells to human T lymphocytes by altering expression of the class II transcriptional activator gene
    • Charreau B, Coupel S, Boulday G, et al. Cyclosporine inhibits class II major histocompatibility antigen presentation by xenogeneic endothelial cells to human T lymphocytes by altering expression of the class II transcriptional activator gene. Transplantation 2000; 70: 354.
    • (2000) Transplantation , vol.70 , pp. 354
    • Charreau, B.1    Coupel, S.2    Boulday, G.3
  • 42
    • 0034161781 scopus 로고    scopus 로고
    • Naturally developing memory T cell xenoreactivity to swine antigens in human peripheral blood lymphocytes
    • Hartig CV, Haller GW, Sachs DH, et al. Naturally developing memory T cell xenoreactivity to swine antigens in human peripheral blood lymphocytes. J Immunol 2000; 164:2790.
    • (2000) J Immunol , vol.164 , pp. 2790
    • Hartig, C.V.1    Haller, G.W.2    Sachs, D.H.3
  • 43
    • 0034637370 scopus 로고    scopus 로고
    • Xenoantigenacity of Chinese Neijiang pig-related to xenotransplantation
    • Li Y, LiT, BuH, etal. Xenoantigenacity of Chinese Neijiang pig-related to xenotransplantation. Transplant Proc 2000; 32: 875.
    • (2000) Transplant Proc , vol.32 , pp. 875
    • Li, Y.1    Li, T.2    Bu, H.3
  • 44
    • 0036556163 scopus 로고    scopus 로고
    • Activation of natural killer cells and macrophages by porcine endothelial cells augments specific T-cell xenoresponse
    • Xu XC, Goodman J, Sasaki H, et al. Activation of natural killer cells and macrophages by porcine endothelial cells augments specific T-cell xenoresponse. Am J Transplant 2002; 2: 314.
    • (2002) Am J Transplant , vol.2 , pp. 314
    • Xu, X.C.1    Goodman, J.2    Sasaki, H.3
  • 45
    • 44449143038 scopus 로고    scopus 로고
    • Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model
    • Saethre M, Schneider MK, Lambris JD, et al. Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model. J Immunol 2008; 180: 6346.
    • (2008) J Immunol , vol.180 , pp. 6346
    • Saethre, M.1    Schneider, M.K.2    Lambris, J.D.3
  • 46
    • 0033136945 scopus 로고    scopus 로고
    • Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: Effector function is linked to proliferative capacity
    • Gudmundsdottir H, Wells AD, Turka LA. Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: Effector function is linked to proliferative capacity. J Immunol 1999; 162: 5212.
    • (1999) J Immunol , vol.162 , pp. 5212
    • Gudmundsdottir, H.1    Wells, A.D.2    Turka, L.A.3
  • 47
    • 0035863825 scopus 로고    scopus 로고
    • Quantifying the frequency of alloreactive T cells in vivo: New answers to an old question
    • Suchin EJ, Langmuir PB, Palmer E, et al. Quantifying the frequency of alloreactive T cells in vivo: New answers to an old question. J Immunol 2001; 166: 973.
    • (2001) J Immunol , vol.166 , pp. 973
    • Suchin, E.J.1    Langmuir, P.B.2    Palmer, E.3
  • 48
    • 0034699367 scopus 로고    scopus 로고
    • Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution
    • Lyons AB. Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution. J Immunol Methods 2000; 243: 147.
    • (2000) J Immunol Methods , vol.243 , pp. 147
    • Lyons, A.B.1
  • 49
    • 33748512099 scopus 로고    scopus 로고
    • Liver sinusoidal endothelial cells that endocytose allogeneic cells suppress T cells with indirect allospecificity
    • Tokita D, Shishida M, Ohdan H, et al. Liver sinusoidal endothelial cells that endocytose allogeneic cells suppress T cells with indirect allospecificity. J Immunol 2006; 177:3615.
    • (2006) J Immunol , vol.177 , pp. 3615
    • Tokita, D.1    Shishida, M.2    Ohdan, H.3
  • 50
    • 0028303645 scopus 로고
    • Demonstration of direct xenorecognition of porcine cells by human cytotoxic T lymphocytes
    • Cunningham AC, Butler TJ, Kirby JA. Demonstration of direct xenorecognition of porcine cells by human cytotoxic T lymphocytes. Immunology 1994; 81: 268.
    • (1994) Immunology , vol.81 , pp. 268
    • Cunningham, A.C.1    Butler, T.J.2    Kirby, J.A.3
  • 51
    • 0030014002 scopus 로고    scopus 로고
    • T-cell-receptor affinity and thymocyte positive selection
    • Alam SM, Travers PJ, Wung JL, et al. T-cell-receptor affinity and thymocyte positive selection. Nature 1996; 381: 616.
    • (1996) Nature , vol.381 , pp. 616
    • Alam, S.M.1    Travers, P.J.2    Wung, J.L.3
  • 52
    • 0035806276 scopus 로고    scopus 로고
    • CD4( + )CD25( + ) immune regula- tory cells are required for induction of tolerance to alloantigen via costimulatory blockade
    • Taylor PA, Noelle RJ, Blazar BR. CD4( + )CD25( + ) immune regula- tory cells are required for induction of tolerance to alloantigen via costimulatory blockade. J Exp Med 2001; 193: 1311.
    • (2001) J Exp Med , vol.193 , pp. 1311
    • Taylor, P.A.1    Noelle, R.J.2    Blazar, B.R.3
  • 53
    • 0035881234 scopus 로고    scopus 로고
    • Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance
    • Gregori S, Casorati M, Amuchastegui S, et al. Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol 2001; 167:1945.
    • (2001) J Immunol , vol.167 , pp. 1945
    • Gregori, S.1    Casorati, M.2    Amuchastegui, S.3
  • 54
    • 0036498560 scopus 로고    scopus 로고
    • Tracking the immunoregulatory mechanisms active during allograft tolerance
    • Sanchez-Fueyo A, Weber M, Domenig C, et al. Tracking the immunoregulatory mechanisms active during allograft tolerance. J Immunol 2002; 168: 2274.
    • (2002) J Immunol , vol.168 , pp. 2274
    • Sanchez-Fueyo, A.1    Weber, M.2    Domenig, C.3
  • 55
    • 0037124359 scopus 로고    scopus 로고
    • Identification of regulatory T cells in tolerated allografts
    • Graca L, Cobbold SP, Waldmann H. Identification of regulatory T cells in tolerated allografts. J Exp Med 2002; 195: 1641.
    • (2002) J Exp Med , vol.195 , pp. 1641
    • Graca, L.1    Cobbold, S.P.2    Waldmann, H.3
  • 56
    • 10744228165 scopus 로고    scopus 로고
    • Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance
    • Zheng XX, Sanchez-Fueyo A, Sho M, et al. Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance. Immunity 2003; 19: 503.
    • (2003) Immunity , vol.19 , pp. 503
    • Zheng, X.X.1    Sanchez-Fueyo, A.2    Sho, M.3
  • 57
    • 33744479421 scopus 로고    scopus 로고
    • Alloantigen-presenting plasma-cytoid dendritic cells mediate tolerance to vascularized grafts
    • Ochando JC, Homma C, Yang Y, et al. Alloantigen-presenting plasma-cytoid dendritic cells mediate tolerance to vascularized grafts. Nat Immunol 2006; 7: 652.
    • (2006) Nat Immunol , vol.7 , pp. 652
    • Ochando, J.C.1    Homma, C.2    Yang, Y.3
  • 58
    • 0035869432 scopus 로고    scopus 로고
    • IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
    • Hara M, Kingsley CI, Niimi M, et al. IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo. J Immunol 2001; 166: 3789.
    • (2001) J Immunol , vol.166 , pp. 3789
    • Hara, M.1    Kingsley, C.I.2    Niimi, M.3
  • 59
    • 0042441104 scopus 로고    scopus 로고
    • Mechanisms of donor-specific transfusion tolerance: Preemptive induction of clonal T-cell exhaustion via indirect presentation
    • Quezada SA, Fuller B, Jarvinen LZ, et al. Mechanisms of donor-specific transfusion tolerance: Preemptive induction of clonal T-cell exhaustion via indirect presentation. Blood 2003; 102: 1920.
    • (2003) Blood , vol.102 , pp. 1920
    • Quezada, S.A.1    Fuller, B.2    Jarvinen, L.Z.3
  • 60
    • 0036597371 scopus 로고    scopus 로고
    • CD4+ CD25+ suppressor T cells: More questions than answers
    • Shevach EM. CD4+ CD25+ suppressor T cells: More questions than answers. Nat Rev Immunol 2002; 2: 389.
    • (2002) Nat Rev Immunol , vol.2 , pp. 389
    • Shevach, E.M.1
  • 61
    • 16844363097 scopus 로고    scopus 로고
    • A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
    • Fontenot JD, Rudensky AY. A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3. Nat Immunol 2005; 6: 331.
    • (2005) Nat Immunol , vol.6 , pp. 331
    • Fontenot, J.D.1    Rudensky, A.Y.2
  • 62
    • 33751207432 scopus 로고    scopus 로고
    • Cell-surface IL-7 receptor expression facilitates the purification of FOXP3(+) regulatory T cells
    • Banham AH. Cell-surface IL-7 receptor expression facilitates the purification of FOXP3(+) regulatory T cells. Trends Immunol 2006; 27: 541.
    • (2006) Trends Immunol , vol.27 , pp. 541
    • Banham, A.H.1
  • 63
    • 33745817085 scopus 로고    scopus 로고
    • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
    • Liu W, Putnam AL, Xu-Yu Z, et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 2006; 203: 1701.
    • (2006) J Exp Med , vol.203 , pp. 1701
    • Liu, W.1    Putnam, A.L.2    Xu-Yu, Z.3
  • 64
    • 33745813929 scopus 로고    scopus 로고
    • Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
    • Seddiki N, Santner-Nanan B, Martinson J, et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006; 203: 1693.
    • (2006) J Exp Med , vol.203 , pp. 1693
    • Seddiki, N.1    Santner-Nanan, B.2    Martinson, J.3
  • 65
    • 33745211931 scopus 로고    scopus 로고
    • Defective regulatory and effector T cell functions in patients with FOXP3 mutations
    • Bacchetta R, Passerini L, Gambineri E, et al. Defective regulatory and effector T cell functions in patients with FOXP3 mutations. J Clin Invest 2006; 116: 1713.
    • (2006) J Clin Invest , vol.116 , pp. 1713
    • Bacchetta, R.1    Passerini, L.2    Gambineri, E.3
  • 66
    • 33646240855 scopus 로고    scopus 로고
    • Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development
    • Gavin MA, Torgerson TR, Houston E, et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci USA 2006; 103:6659.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6659
    • Gavin, M.A.1    Torgerson, T.R.2    Houston, E.3
  • 67
    • 33847125247 scopus 로고    scopus 로고
    • Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
    • Wan YY, Flavell RA. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature 2007; 445: 766.
    • (2007) Nature , vol.445 , pp. 766
    • Wan, Y.Y.1    Flavell, R.A.2
  • 68
    • 33847698972 scopus 로고    scopus 로고
    • Regulatory T-cell development: Is Foxp3 the decider?
    • Curiel TJ. Regulatory T-cell development: Is Foxp3 the decider? Nat Med 2007; 13: 250.
    • (2007) Nat Med , vol.13 , pp. 250
    • Curiel, T.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.