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For recent examples of the catalytic carbene-transfer reactions via in situ generation of carbenoid species having electron- withdrawing groups at carbene carbons, see
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For recent examples of the catalytic carbene-transfer reactions via in situ generation of carbenoid species having electron- withdrawing groups at carbene carbons, see:
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The reaction of le with 10 equivalents of cyclopentadiene at room temperature afforded mono-cyclopropanated product in 88% yield for 1.5 h.
-
The reaction of le with 10 equivalents of cyclopentadiene at room temperature afforded mono-cyclopropanated product in 88% yield for 1.5 h.
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79
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58149317443
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The structure of 18d was determined by NOE experiments. See the Supporting Information. The reaction of 17d with 1.1 equivalents of NaH at 0 °C for 15 min gave the cyclized N-phenyl- morpholin-2-one 18d in 43% yield. This indicates the structure of 17d is an N-adduct.
-
The structure of 18d was determined by NOE experiments. See the Supporting Information. The reaction of 17d with 1.1 equivalents of NaH at 0 °C for 15 min gave the cyclized N-phenyl- morpholin-2-one 18d in 43% yield. This indicates the structure of 17d is an N-adduct.
-
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80
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58149309713
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5-Alkylidene-2,5-dihydrofuran 25b was kinetically obtained as a primary product. The structure of 25b and 25b′ were determined by X-ray crystallography. See Supporting Information.
-
5-Alkylidene-2,5-dihydrofuran 25b was kinetically obtained as a primary product. The structure of 25b and 25b′ were determined by X-ray crystallography. See Supporting Information.
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81
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58149291078
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Nucleophilic conjugate addition reactions to aromatic rings of Fischer-type phenyl and furylcarbene complexes have been reported by Barluenga et al. See
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Nucleophilic conjugate addition reactions to aromatic rings of Fischer-type phenyl and furylcarbene complexes have been reported by Barluenga et al. See:
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