Glutamatergic stimulation triggers rapid Krüpple-like factor 4 expression in neurons and the overexpression of KLF4 sensitizes neurons to NMDA-induced caspase-3 activity

Brain Research

Volumn 1250, Issue , 2009, Pages 49-62

  Zhu, Shanshan ^a   Tai, Chao ^a   MacVicar, Brian A ^a   Jia, William ^a   Cynader, Max S ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Apoptosis; Caspase 3; Cell cycle; Cyclin D1; Kr pple like factor 4; NMDA excitotoxicity

Indexed keywords

CASPASE 3; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; KRUPPEL LIKE FACTOR 4; LENTIVIRUS VECTOR; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL CULTURE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

ANIMALS; BLOTTING, WESTERN; CASPASE 3; CELLS, CULTURED; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; ENZYME ACTIVATION; GLUTAMIC ACID; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; N-METHYLASPARTATE; NEURONS; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; UP-REGULATION;

EID: 58149302692     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.11.013     Document Type: Article

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