메뉴 건너뛰기




Volumn 45, Issue , 2008, Pages 83-94

Modelling cellular signalling systems

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; BIOLOGICAL MODEL; CELL; HUMAN; METABOLISM; REPRODUCIBILITY; REVIEW; SIGNAL TRANSDUCTION;

EID: 58149237830     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/BSE0450083     Document Type: Article
Times cited : (23)

References (43)
  • 1
    • 0033515888 scopus 로고    scopus 로고
    • Complexity in biological signaling systems
    • Weng, G., Bhalla, U.S. & lyengar, R. (1999) Complexity in biological signaling systems. Science 284, 92-96
    • (1999) Science , vol.284 , pp. 92-96
    • Weng, G.1    Bhalla, U.S.2    lyengar, R.3
  • 2
    • 0029775654 scopus 로고    scopus 로고
    • Cell motility driven by actin polymerization
    • Mogilner, A. & Oster, G. (1996) Cell motility driven by actin polymerization. Biophys. J. 71, 3030-3045
    • (1996) Biophys. J , vol.71 , pp. 3030-3045
    • Mogilner, A.1    Oster, G.2
  • 3
    • 0036708436 scopus 로고    scopus 로고
    • Regulation of actin dynamics in rapidly moving cells: A quantitative analysis
    • Mogilner, A. & Edelstein-Keshet, L (2002) Regulation of actin dynamics in rapidly moving cells: a quantitative analysis. Biophys. J. 83, 1237-1258
    • (2002) Biophys. J , vol.83 , pp. 1237-1258
    • Mogilner, A.1    Edelstein-Keshet, L.2
  • 4
    • 0037339268 scopus 로고    scopus 로고
    • Force generation by actin polymerization II: The elastic ratchet and tethered filaments
    • Mogilner, A. & Oster, G. (2003) Force generation by actin polymerization II: the elastic ratchet and tethered filaments. Biophys. J. 84, 1591-1605
    • (2003) Biophys. J , vol.84 , pp. 1591-1605
    • Mogilner, A.1    Oster, G.2
  • 5
    • 33845605130 scopus 로고    scopus 로고
    • a. Sible, J.C. & Tyson, J.J. (2007) Mathematical modeling as a tool for investigating cell cycle control networks. Methods 41, 238-247
    • a. Sible, J.C. & Tyson, J.J. (2007) Mathematical modeling as a tool for investigating cell cycle control networks. Methods 41, 238-247
  • 6
    • 0242515913 scopus 로고    scopus 로고
    • The JNK cascade as a biochemical switch in mammalian cells: Ultrasensitive and all-or-none responses
    • Bagowski, C.P., Besser, J., Frey, C.R. & Ferrell, Jr, J.E. (2003) The JNK cascade as a biochemical switch in mammalian cells: ultrasensitive and all-or-none responses. Curr. Biol. 13, 315-320
    • (2003) Curr. Biol , vol.13 , pp. 315-320
    • Bagowski, C.P.1    Besser, J.2    Frey, C.R.3    Ferrell Jr, J.E.4
  • 7
    • 0029790351 scopus 로고    scopus 로고
    • Ultrasensitive in the mitogen-activated protein kinase cascade
    • Huang, C.Y. & Ferrell, Jr, J.E. (1996) Ultrasensitive in the mitogen-activated protein kinase cascade. Proc Natl. Acad. Sci. U.S.A. 93, 10078-10083
    • (1996) Proc Natl. Acad. Sci. U.S.A , vol.93 , pp. 10078-10083
    • Huang, C.Y.1    Ferrell Jr, J.E.2
  • 8
    • 17644427718 scopus 로고    scopus 로고
    • Causal protein-signaling networks derived from multiparameter single-cell data
    • Sachs, K., Perez, O., Pe'er, D., Lauffenburger, D.A. & Nolan, G.P. (2005) Causal protein-signaling networks derived from multiparameter single-cell data. Science 308, 523-529
    • (2005) Science , vol.308 , pp. 523-529
    • Sachs, K.1    Perez, O.2    Pe'er, D.3    Lauffenburger, D.A.4    Nolan, G.P.5
  • 9
    • 0036212767 scopus 로고    scopus 로고
    • Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors
    • Schoeberl, B., Eichler-Jonsson, C., Gilles, E.D. & Müller, G. (2002) Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors. Not. Biotechnol. 20, 370-375
    • (2002) Not. Biotechnol , vol.20 , pp. 370-375
    • Schoeberl, B.1    Eichler-Jonsson, C.2    Gilles, E.D.3    Müller, G.4
  • 10
    • 23244456797 scopus 로고    scopus 로고
    • Computational model for cell migration in three-dimensional matrices
    • Zaman, M.H., Kamm, R.D., Matsudaira, P. & Lauffenburger, D.A. (2005) Computational model for cell migration in three-dimensional matrices. Biophys. J. 89, 1389-1397
    • (2005) Biophys. J , vol.89 , pp. 1389-1397
    • Zaman, M.H.1    Kamm, R.D.2    Matsudaira, P.3    Lauffenburger, D.A.4
  • 11
    • 1342265607 scopus 로고    scopus 로고
    • Experimental design in systems biology, based on parameter sensitivity analysis using a Monte Carlo method: A case study for the TNF-α mediated NF-κB signal transduction pathway
    • Cho, K.H., Shin, S.Y., Kolch, W. & Wolkenhauer, O. (2003) Experimental design in systems biology, based on parameter sensitivity analysis using a Monte Carlo method: a case study for the TNF-α mediated NF-κB signal transduction pathway. Simulation 79, 726-739
    • (2003) Simulation , vol.79 , pp. 726-739
    • Cho, K.H.1    Shin, S.Y.2    Kolch, W.3    Wolkenhauer, O.4
  • 12
    • 24944489952 scopus 로고    scopus 로고
    • Stimulus specificity of gene expression programs determined by temporal control of IKK activity
    • Werner, S.L., Barken, D. & Hoffmann, A. (2005) Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science 309, 1857-1861
    • (2005) Science , vol.309 , pp. 1857-1861
    • Werner, S.L.1    Barken, D.2    Hoffmann, A.3
  • 13
    • 0042338691 scopus 로고    scopus 로고
    • Tsien, R.Y. (2003) Imagining imaging's future. Not. Rev. Mol. Cell Biol. Sep Suppl, SS16-SS21
    • Tsien, R.Y. (2003) Imagining imaging's future. Not. Rev. Mol. Cell Biol. Sep Suppl, SS16-SS21
  • 14
    • 0034083428 scopus 로고    scopus 로고
    • Recent advances in technology for measuring and manipulating cell signals
    • Zacharias, D.A., Baird, G.S. & Tsien, R.Y. (2000) Recent advances in technology for measuring and manipulating cell signals. Curr. Opin. Neurobiol. 10, 416-421
    • (2000) Curr. Opin. Neurobiol , vol.10 , pp. 416-421
    • Zacharias, D.A.1    Baird, G.S.2    Tsien, R.Y.3
  • 15
    • 28444477387 scopus 로고    scopus 로고
    • Plasma membrane phosphoinositide organization by protein electrostatics
    • McLaughlin, S. & Murray, D. (2005) Plasma membrane phosphoinositide organization by protein electrostatics. Nature 438, 605-611
    • (2005) Nature , vol.438 , pp. 605-611
    • McLaughlin, S.1    Murray, D.2
  • 17
    • 0033555859 scopus 로고    scopus 로고
    • Emergent properties of networks of biological signaling pathways
    • Bhalla, U.S. & lyengar, R. (1999) Emergent properties of networks of biological signaling pathways. Science 283, 381-387
    • (1999) Science , vol.283 , pp. 381-387
    • Bhalla, U.S.1    lyengar, R.2
  • 18
    • 29144435996 scopus 로고    scopus 로고
    • Computational modelling of the receptor-tyrosine-kinase- activated MAPK pathway
    • Orton, R.J., Sturm, O.E., Vyshemirsky, V., Calder, M., Gilbert, D.R. & Kolch, W. (2005) Computational modelling of the receptor-tyrosine-kinase- activated MAPK pathway. Biochem. J. 392, 249-261
    • (2005) Biochem. J , vol.392 , pp. 249-261
    • Orton, R.J.1    Sturm, O.E.2    Vyshemirsky, V.3    Calder, M.4    Gilbert, D.R.5    Kolch, W.6
  • 19
    • 14844318077 scopus 로고    scopus 로고
    • When kinases meet mathematics: The systems biology of MAPK signalling
    • Kolch, W., Calder, M. & Gilbert, D. (2005) When kinases meet mathematics: the systems biology of MAPK signalling. FEBS Lett. 579, 1891-1895
    • (2005) FEBS Lett , vol.579 , pp. 1891-1895
    • Kolch, W.1    Calder, M.2    Gilbert, D.3
  • 20
    • 16344377134 scopus 로고    scopus 로고
    • MAPK cascade possesses decoupled controllability of signal amplification and duration
    • Mayawala, K., Gelmi, C.A. & Edwards, J.S. (2004) MAPK cascade possesses decoupled controllability of signal amplification and duration. Biophys. J. 87, L01-L02
    • (2004) Biophys. J , vol.87
    • Mayawala, K.1    Gelmi, C.A.2    Edwards, J.S.3
  • 21
    • 0034914737 scopus 로고    scopus 로고
    • A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (MAPK) pathway model
    • Asthagiri, A.R. & Lauffenburger, D.A. (2001) A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (MAPK) pathway model. Biotechnol. Prog. 17, 227-239
    • (2001) Biotechnol. Prog , vol.17 , pp. 227-239
    • Asthagiri, A.R.1    Lauffenburger, D.A.2
  • 22
    • 34848887670 scopus 로고    scopus 로고
    • Competing docking interactions can bring about bistability in the MAPK cascade
    • Legewie, S., Schoeberl, B., Blüthgen, N. & Herzel, H. (2007) Competing docking interactions can bring about bistability in the MAPK cascade. Biophys. J. 93, 2279-2288
    • (2007) Biophys. J , vol.93 , pp. 2279-2288
    • Legewie, S.1    Schoeberl, B.2    Blüthgen, N.3    Herzel, H.4
  • 23
    • 0030445778 scopus 로고    scopus 로고
    • Tripping the switch fantastic: How a protein kinase cascade can convert graded inputs into switch-like outputs
    • Ferrell, Jr, J.E. (1996) Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs. Trends Biochem. Sci. 21, 460-466
    • (1996) Trends Biochem. Sci , vol.21 , pp. 460-466
    • Ferrell Jr, J.E.1
  • 24
    • 0031203921 scopus 로고    scopus 로고
    • How responses get more switch-like as you move down a protein kinase cascade
    • Ferrell, Jr, J.E. (1997) How responses get more switch-like as you move down a protein kinase cascade. Trends Biochem. Sci. 22, 288-289
    • (1997) Trends Biochem. Sci , vol.22 , pp. 288-289
    • Ferrell Jr, J.E.1
  • 25
    • 0033555854 scopus 로고    scopus 로고
    • What maintains memories?
    • Lisman, J.E. & Fallon, J.R. (1999) What maintains memories? Science 283, 339-340
    • (1999) Science , vol.283 , pp. 339-340
    • Lisman, J.E.1    Fallon, J.R.2
  • 26
    • 0037047607 scopus 로고    scopus 로고
    • Signal transduction. History matters
    • Ingolia, N.T. & Murray, A.W. (2002) Signal transduction. History matters. Science 297, 948-949
    • (2002) Science , vol.297 , pp. 948-949
    • Ingolia, N.T.1    Murray, A.W.2
  • 27
    • 0037047611 scopus 로고    scopus 로고
    • MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network
    • Bhalla, U.S., Ram, P.T. & lyengar, R. (2002) MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 297, 1018-1023
    • (2002) Science , vol.297 , pp. 1018-1023
    • Bhalla, U.S.1    Ram, P.T.2    lyengar, R.3
  • 28
    • 33846295551 scopus 로고    scopus 로고
    • The effects of time delays in a phosphorylation-dephosphorylation pathway
    • Srividhya, J., Gopinathan, M.S. & Schnell, S. (2007) The effects of time delays in a phosphorylation-dephosphorylation pathway. Biophys. Chem. 125, 286-297
    • (2007) Biophys. Chem , vol.125 , pp. 286-297
    • Srividhya, J.1    Gopinathan, M.S.2    Schnell, S.3
  • 29
    • 33745809191 scopus 로고    scopus 로고
    • A simple time delay model for eukaryotic cell cycle
    • Srividhya, J. & Gopinathan, M.S. (2006) A simple time delay model for eukaryotic cell cycle. J. Theor. Biol. 241, 617-627
    • (2006) J. Theor. Biol , vol.241 , pp. 617-627
    • Srividhya, J.1    Gopinathan, M.S.2
  • 30
    • 34547564902 scopus 로고    scopus 로고
    • Survival and apoptotic pathways initiated by TNF-α modeling and predictions
    • Rangamani, P. & Sirovich, L. (2006) Survival and apoptotic pathways initiated by TNF-α modeling and predictions. Biotechnol. Bioeng. 97, 1216-1229
    • (2006) Biotechnol. Bioeng , vol.97 , pp. 1216-1229
    • Rangamani, P.1    Sirovich, L.2
  • 31
    • 3042668006 scopus 로고    scopus 로고
    • In silico simulation of inhibitor drug effects on nuclear factor-κB pathway dynamics
    • Sung, M.H. & Simon, R. (2004) In silico simulation of inhibitor drug effects on nuclear factor-κB pathway dynamics. Mol. Pharmacol. 66, 70-75
    • (2004) Mol. Pharmacol , vol.66 , pp. 70-75
    • Sung, M.H.1    Simon, R.2
  • 32
    • 33846826944 scopus 로고    scopus 로고
    • Compartment-specific feedback loop and regulated trafficking can result in sustained activation of Ras at the Golgi
    • Eungdamrong, N.J. & lyengar, R. (2007) Compartment-specific feedback loop and regulated trafficking can result in sustained activation of Ras at the Golgi. Biophys. J. 92, 808-815
    • (2007) Biophys. J , vol.92 , pp. 808-815
    • Eungdamrong, N.J.1    lyengar, R.2
  • 33
    • 0034638836 scopus 로고    scopus 로고
    • Spatial sensing in fibroblasts mediated by 3′ phosphoinositides
    • Haugh, J.M., Codazzi, F., Teruel, M. & Meyer, T. (2000) Spatial sensing in fibroblasts mediated by 3′ phosphoinositides. J. Cell Biol. 151, 1269-1280
    • (2000) J. Cell Biol , vol.151 , pp. 1269-1280
    • Haugh, J.M.1    Codazzi, F.2    Teruel, M.3    Meyer, T.4
  • 34
    • 0347319164 scopus 로고    scopus 로고
    • Spatial analysis of 3′ phosphoinositide signaling in living fibroblasts: I. Uniform stimulation model and bounds on dimensionless groups
    • Haugh, J.M. & Schneider, I.C. (2004) Spatial analysis of 3′ phosphoinositide signaling in living fibroblasts: I. Uniform stimulation model and bounds on dimensionless groups. Biophys. J. 86, 589-598
    • (2004) Biophys. J , vol.86 , pp. 589-598
    • Haugh, J.M.1    Schneider, I.C.2
  • 35
    • 0347319166 scopus 로고    scopus 로고
    • Spatial analysis of 3′ phosphoinositide signaling in living fibroblasts: II. Parameter estimates for individual cells from experiments
    • Schneider, I.C. & Haugh, J.M. (2004) Spatial analysis of 3′ phosphoinositide signaling in living fibroblasts: II. Parameter estimates for individual cells from experiments. Biophys. J. 86, 599-608
    • (2004) Biophys. J , vol.86 , pp. 599-608
    • Schneider, I.C.1    Haugh, J.M.2
  • 36
    • 33846781374 scopus 로고    scopus 로고
    • Phosphoinositides and Rho proteins spatially regulate actin polymerization to initiate and maintain directed movement in a one-dimensional model of a motile cell
    • Dawes, A.T. & Edelstein-Keshet, L. (2007) Phosphoinositides and Rho proteins spatially regulate actin polymerization to initiate and maintain directed movement in a one-dimensional model of a motile cell. Biophys. J. 92, 744-768
    • (2007) Biophys. J , vol.92 , pp. 744-768
    • Dawes, A.T.1    Edelstein-Keshet, L.2
  • 37
    • 34249950625 scopus 로고    scopus 로고
    • Stochastic simulation of chemical kinetics
    • Gillespie, D.T. (2007) Stochastic simulation of chemical kinetics. Annu. Rev. Phys. Chem. 58, 35-55
    • (2007) Annu. Rev. Phys. Chem , vol.58 , pp. 35-55
    • Gillespie, D.T.1
  • 38
    • 33645429016 scopus 로고
    • Exact stochastic simulation of coupled chemical reactions
    • Gillespie, D.T. (1977) Exact stochastic simulation of coupled chemical reactions. J. Phys. Chem. 81, 2340-2361
    • (1977) J. Phys. Chem , vol.81 , pp. 2340-2361
    • Gillespie, D.T.1
  • 39
    • 0347724159 scopus 로고    scopus 로고
    • Adaptive stochastic-deterministic chemical kinetic simulations
    • Vasudeva, K. & Bhalla, U.S. (2004) Adaptive stochastic-deterministic chemical kinetic simulations. Bioinformatics 20, 78-84
    • (2004) Bioinformatics , vol.20 , pp. 78-84
    • Vasudeva, K.1    Bhalla, U.S.2
  • 40
    • 14044265753 scopus 로고    scopus 로고
    • Samoilov, M., Plyasunov, S. & Arkin, A.P. (2005) Stochastic amplification and signaling in enzymatic futile cycles through noise-induced bistability with oscillations. Proc Natl. Acad. Sci. U.S.A. 102, 2310-2315
    • Samoilov, M., Plyasunov, S. & Arkin, A.P. (2005) Stochastic amplification and signaling in enzymatic futile cycles through noise-induced bistability with oscillations. Proc Natl. Acad. Sci. U.S.A. 102, 2310-2315
  • 41
    • 33746373126 scopus 로고    scopus 로고
    • Developing Ito stochastic differential equation models for neuronal signal transduction pathways
    • Manninen, T., Linne, M.L & Ruohonen, K. (2006) Developing Ito stochastic differential equation models for neuronal signal transduction pathways. Comp. Biol. Chem. 30, 280-291
    • (2006) Comp. Biol. Chem , vol.30 , pp. 280-291
    • Manninen, T.1    Linne, M.L.2    Ruohonen, K.3
  • 42
    • 68349128980 scopus 로고    scopus 로고
    • Reference deleted
    • Reference deleted
  • 43
    • 0347004632 scopus 로고    scopus 로고
    • The next step in systems biology: Simulating the temporospatial dynamics of molecular networks
    • Zhu, H., Huang, S. & Dhar, P. (2004) The next step in systems biology: simulating the temporospatial dynamics of molecular networks. BioEssays 26, 68-72
    • (2004) BioEssays , vol.26 , pp. 68-72
    • Zhu, H.1    Huang, S.2    Dhar, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.