Activated STAT3 is a mediator and biomarker of VEGF endothelial activation

Cancer Biology and Therapy

Volumn 7, Issue 12, 2008, Pages 1994-2003

  Chen, Shao Hua ^a,b,d   Murphy, Danielle A ^a,b   Lassoued, Wiem ^a,b   Thurston, Gavin ^c   Feldman, Michael D ^a,b   Lee, William M F ^a,b,e  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c REGENERON PHARMACEUTICALS INC   (United States)

^d Louisiana State University School of Medicine Shreveport   (United States)

^e NONE   (United States)

Author keywords

Angiogenesis; Antiangiogenic therapy; Bcl 2; Biomarker; Endothelial cells; Signal transduction; STAT3; Tumor; VEGF; VEGFR2

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; AFLIBERCEPT; FIBROBLAST GROWTH FACTOR 2; PROTEIN BCL 2; PROTEIN TYROSINE KINASE; SEMAXANIB; STAT3 PROTEIN; TUMOR MARKER; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; MELANOMA; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; TUMOR VASCULARIZATION;

EID: 58149122747     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.7.12.6967     Document Type: Article

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