-
2
-
-
0028296179
-
Association of transcription factor APRF and protein kinase JAK1 with the IL-6 signal transducer gp130
-
Lütticken C, Wegenka UM, Yuan J, et al. Association of transcription factor APRF and protein kinase JAK1 with the IL-6 signal transducer gp130. Science. 1994;263:89-92.
-
(1994)
Science
, vol.263
, pp. 89-92
-
-
Lütticken, C.1
Wegenka, U.M.2
Yuan, J.3
-
3
-
-
0028931604
-
Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors
-
Stahl N, Farruggella TJ, Boulton TG, Zhong Z, Darnell JE Jr, Yancopoulos GD. Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science. 1995;267:1349-1353.
-
(1995)
Science
, vol.267
, pp. 1349-1353
-
-
Stahl, N.1
Farruggella, T.J.2
Boulton, T.G.3
Zhong, Z.4
Darnell Jr., J.E.5
Yancopoulos, G.D.6
-
4
-
-
0029991793
-
Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation
-
Hemmann U, Gerhartz C, Heesel B, et al. Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation. J Biol Chem. 1996;271:12999-13007.
-
(1996)
J Biol Chem
, vol.271
, pp. 12999-13007
-
-
Hemmann, U.1
Gerhartz, C.2
Heesel, B.3
-
5
-
-
0034724677
-
SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
-
Schmitz J, Weissenbach M, Haan S, Heinrich PC, Schaper F. SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130. J Biol Chem. 2000;275:12848-12856.
-
(2000)
J Biol Chem
, vol.275
, pp. 12848-12856
-
-
Schmitz, J.1
Weissenbach, M.2
Haan, S.3
Heinrich, P.C.4
Schaper, F.5
-
6
-
-
0034612271
-
Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130
-
Nicholson SE, De Souza D, Fabri LJ, et al. Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130. Proc Natl Acad Sci U S A. 2000;97:6493-6498.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6493-6498
-
-
Nicholson, S.E.1
De Souza, D.2
Fabri, L.J.3
-
7
-
-
0030292721
-
Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis
-
Fukada T, Hibi M, Yamanaka Y, et al. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis. Immunity. 1996;5:449-460.
-
(1996)
Immunity
, vol.5
, pp. 449-460
-
-
Fukada, T.1
Hibi, M.2
Yamanaka, Y.3
-
8
-
-
0033551802
-
Intedeukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways
-
Chen RH, Chang MC, Su YH, Tsai YT, Kuo ML. Intedeukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways. J Biol Chem. 1999;274:23013-23019.
-
(1999)
J Biol Chem
, vol.274
, pp. 23013-23019
-
-
Chen, R.H.1
Chang, M.C.2
Su, Y.H.3
Tsai, Y.T.4
Kuo, M.L.5
-
9
-
-
0032788884
-
Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells
-
Kim H, Baumann H. Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells. Mol Cell Biol. 1999;19:5326-5338.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5326-5338
-
-
Kim, H.1
Baumann, H.2
-
10
-
-
0033559311
-
Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors
-
Nishida K, Yoshida Y, Itoh M, et al. Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors. Blood. 1999;93:1809-1816.
-
(1999)
Blood
, vol.93
, pp. 1809-1816
-
-
Nishida, K.1
Yoshida, Y.2
Itoh, M.3
-
11
-
-
0030792590
-
A family of cytokine-inducible inhibitors of signalling
-
Starr R, Willson TA, Viney EM, et al. A family of cytokine-inducible inhibitors of signalling. Nature. 1997;387:917-921.
-
(1997)
Nature
, vol.387
, pp. 917-921
-
-
Starr, R.1
Willson, T.A.2
Viney, E.M.3
-
12
-
-
0027441586
-
Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level
-
Wegenka UM, Buschmann J, Lütticken C, Heinrich PC, Horn F. Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level. Mol Cell Biol. 1993;13:276-288.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 276-288
-
-
Wegenka, U.M.1
Buschmann, J.2
Lütticken, C.3
Heinrich, P.C.4
Horn, F.5
-
13
-
-
0028211553
-
The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements
-
Yuan J, Wegenka UM, Lütticken C, et al. The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements. Mol Cell Biol. 1994;14:1657-1668.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1657-1668
-
-
Yuan, J.1
Wegenka, U.M.2
Lütticken, C.3
-
16
-
-
0029002318
-
Prevention of myeloma cell apoptosis by ectopic bcl-2 expression or interleukin 6-mediated up-regulation of bcl-xL
-
Schwarze MM, Hawley RG. Prevention of myeloma cell apoptosis by ectopic bcl-2 expression or interleukin 6-mediated up-regulation of bcl-xL. Cancer Res. 1995;55:2262-2265.
-
(1995)
Cancer Res
, vol.55
, pp. 2262-2265
-
-
Schwarze, M.M.1
Hawley, R.G.2
-
17
-
-
0032984589
-
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
-
Catlett-Falcone R, Landowski TH, Oshiro MM, et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity. 1999;10:105-115.
-
(1999)
Immunity
, vol.10
, pp. 105-115
-
-
Catlett-Falcone, R.1
Landowski, T.H.2
Oshiro, M.M.3
-
18
-
-
0034669993
-
Constitutive activation of STAT3 is associated with the acquisition of an interleukin 6-independent phenotype by murine plasmacytomas and hybridomas
-
Rawat R, Rainey GJ, Thompson CD, Frazier-Jessen MR, Brown RT, Nordan RP. Constitutive activation of STAT3 is associated with the acquisition of an interleukin 6-independent phenotype by murine plasmacytomas and hybridomas. Blood. 2000;96:3514-3521.
-
(2000)
Blood
, vol.96
, pp. 3514-3521
-
-
Rawat, R.1
Rainey, G.J.2
Thompson, C.D.3
Frazier-Jessen, M.R.4
Brown, R.T.5
Nordan, R.P.6
-
19
-
-
0035127222
-
Interferon alpha extends the survival of human myeloma cells through an upregulation of the Mcl-1 anti-apoptotic molecule
-
Puthier D, Thabard W, Rapp M, et al. Interferon alpha extends the survival of human myeloma cells through an upregulation of the Mcl-1 anti-apoptotic molecule. Br J Haematol. 2001;112:358-363.
-
(2001)
Br J Haematol
, vol.112
, pp. 358-363
-
-
Puthier, D.1
Thabard, W.2
Rapp, M.3
-
20
-
-
85047696564
-
Role of the AKT kinase in expansion of multiple myeloma clones: Effects on cytokine-dependent proliferative and survival responses
-
Hsu JH, Shi Y, Hu L, Fisher M, Franke TF, Lichtenstein A. Role of the AKT kinase in expansion of multiple myeloma clones: effects on cytokine-dependent proliferative and survival responses. Oncogene. 2002;21:1391-1400.
-
(2002)
Oncogene
, vol.21
, pp. 1391-1400
-
-
Hsu, J.H.1
Shi, Y.2
Hu, L.3
Fisher, M.4
Franke, T.F.5
Lichtenstein, A.6
-
21
-
-
0035525792
-
The AKT kinase is activated in multiple myeloma tumor cells
-
Hsu J, Shi Y, Krajewski S, et al. The AKT kinase is activated in multiple myeloma tumor cells. Blood. 2001;98:2853-2855.
-
(2001)
Blood
, vol.98
, pp. 2853-2855
-
-
Hsu, J.1
Shi, Y.2
Krajewski, S.3
-
22
-
-
0035921689
-
Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma
-
Hideshima T, Nakamura N, Chauhan D, Anderson KC. Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma. Oncogene. 2001;20:5991-6000.
-
(2001)
Oncogene
, vol.20
, pp. 5991-6000
-
-
Hideshima, T.1
Nakamura, N.2
Chauhan, D.3
Anderson, K.C.4
-
23
-
-
0034548453
-
The phosphatidylinositol 3-kinase/AKT kinase pathway in multiple myeloma plasma cells: Roles in cytokine-dependent survival and proliferative responses
-
Tu Y, Gardner A, Lichtenstein A. The phosphatidylinositol 3-kinase/AKT kinase pathway in multiple myeloma plasma cells: roles in cytokine-dependent survival and proliferative responses. Cancer Res. 2000;60:6763-6770.
-
(2000)
Cancer Res
, vol.60
, pp. 6763-6770
-
-
Tu, Y.1
Gardner, A.2
Lichtenstein, A.3
-
24
-
-
0032125757
-
Interleukin-6-induced inhibition of multiple myeloma cell apoptosis: Support for the hypothesis that protection is mediated via inhibition of the JNK/SAPK pathway
-
Xu FH, Sharma S, Gardner A, et al. Interleukin-6-induced inhibition of multiple myeloma cell apoptosis: support for the hypothesis that protection is mediated via inhibition of the JNK/SAPK pathway. Blood. 1998;92:241-251.
-
(1998)
Blood
, vol.92
, pp. 241-251
-
-
Xu, F.H.1
Sharma, S.2
Gardner, A.3
-
25
-
-
0031225483
-
IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade
-
Ogata A, Chauhan D, Teoh G, et al. IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade. J Immunol. 1997;159:2212-2221.
-
(1997)
J Immunol
, vol.159
, pp. 2212-2221
-
-
Ogata, A.1
Chauhan, D.2
Teoh, G.3
-
26
-
-
0034525417
-
Regulation of Bcl-2-family proteins in myeloma cells by three myeloma survival factors: Interleukin-6, interferon-alpha and insulin-like growth factor 1
-
Jourdan M, De Vos J, Mechti N, Klein B. Regulation of Bcl-2-family proteins in myeloma cells by three myeloma survival factors: interleukin-6, interferon-alpha and insulin-like growth factor 1. Cell Death Differ. 2000;7:1244-1252.
-
(2000)
Cell Death Differ
, vol.7
, pp. 1244-1252
-
-
Jourdan, M.1
De Vos, J.2
Mechti, N.3
Klein, B.4
-
27
-
-
0032750492
-
Mcl-1 and Bcl-xL are co-regulated by IL-6 in human myeloma cells
-
Puthier D, Derenne S, Barille S, et al. Mcl-1 and Bcl-xL are co-regulated by IL-6 in human myeloma cells. Br J Haematol. 1999;107:392-395.
-
(1999)
Br J Haematol
, vol.107
, pp. 392-395
-
-
Puthier, D.1
Derenne, S.2
Barille, S.3
-
28
-
-
0036659905
-
Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells
-
Derenne S, Monia B, Dean NM, et al. Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells. Blood. 2002;100:194-199.
-
(2002)
Blood
, vol.100
, pp. 194-199
-
-
Derenne, S.1
Monia, B.2
Dean, N.M.3
-
29
-
-
0038021146
-
A major role for Mcl-1 antiapoptotic protein in the IL-6-induced survival of human myeloma cells
-
Jourdan M, Veyrune JL, Vos JD, Redal N, Couderc G, Klein B. A major role for Mcl-1 antiapoptotic protein in the IL-6-induced survival of human myeloma cells. Oncogene. 2003;22:2950-2959.
-
(2003)
Oncogene
, vol.22
, pp. 2950-2959
-
-
Jourdan, M.1
Veyrune, J.L.2
Vos, J.D.3
Redal, N.4
Couderc, G.5
Klein, B.6
-
30
-
-
0035136846
-
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
-
Epling-Burnette PK, Liu JH, Catlett-Falcone R, et al. Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. J Clin Invest. 2001;107:351-362.
-
(2001)
J Clin Invest
, vol.107
, pp. 351-362
-
-
Epling-Burnette, P.K.1
Liu, J.H.2
Catlett-Falcone, R.3
-
31
-
-
0035825596
-
The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6
-
Kuo ML, Chuang SE, Lin MT, Yang SY. The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6. Oncogene. 2001;20:677-685.
-
(2001)
Oncogene
, vol.20
, pp. 677-685
-
-
Kuo, M.L.1
Chuang, S.E.2
Lin, M.T.3
Yang, S.Y.4
-
32
-
-
0035855625
-
The anti-apoptotic role of interleukin-6 in human cervical cancer is mediated by up-regulation of Mcl-1 through a PI 3-K/Akt pathway
-
Wei LH, Kuo ML, Chen CA, et al. The anti-apoptotic role of interleukin-6 in human cervical cancer is mediated by up-regulation of Mcl-1 through a PI 3-K/Akt pathway. Oncogene. 2001;20:5799-5809.
-
(2001)
Oncogene
, vol.20
, pp. 5799-5809
-
-
Wei, L.H.1
Kuo, M.L.2
Chen, C.A.3
-
33
-
-
0035876931
-
Cooperative regulation of Mcl-1 by Janus kinase/stat and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils
-
Epling-Burnette PK, Zhong B, Bai F, et al. Cooperative regulation of Mcl-1 by Janus kinase/stat and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils. J Immunol. 2001;166:7486-7495.
-
(2001)
J Immunol
, vol.166
, pp. 7486-7495
-
-
Epling-Burnette, P.K.1
Zhong, B.2
Bai, F.3
-
34
-
-
0037468570
-
IL-6-independent expression of Mcl-1 in human multiple myeloma
-
Zhang B, Potyagaylo V, Fenton RG. IL-6-independent expression of Mcl-1 in human multiple myeloma. Oncogene. 2003;22:1848-1859.
-
(2003)
Oncogene
, vol.22
, pp. 1848-1859
-
-
Zhang, B.1
Potyagaylo, V.2
Fenton, R.G.3
-
35
-
-
0035068530
-
Gp130 and ras mediated signaling in human plasma cell line INA-6: A cytokine-regulated tumor model for plasmacytoma
-
Burger R, Guenther A, Bakker F, et al. Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma. Hematol J. 2001;2:42-53.
-
(2001)
Hematol J
, vol.2
, pp. 42-53
-
-
Burger, R.1
Guenther, A.2
Bakker, F.3
-
36
-
-
0030025735
-
Detection of receptors for interleukin-6, interleukin-11, leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in bone marrow stromal/osteoblastic cells
-
Bellido T, Stahl N, Farruggella TJ, Borba V, Yancopoulos GD, Manolagas SC. Detection of receptors for interleukin-6, interleukin-11, leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in bone marrow stromal/osteoblastic cells. J Clin Invest. 1996;97:431-437.
-
(1996)
J Clin Invest
, vol.97
, pp. 431-437
-
-
Bellido, T.1
Stahl, N.2
Farruggella, T.J.3
Borba, V.4
Yancopoulos, G.D.5
Manolagas, S.C.6
-
38
-
-
0029887373
-
Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130, I: Definition of a novel phosphotyrosine motif mediating STAT1 activation
-
Gerhartz C, Heesel B, Sasse J, et al. Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130, I: definition of a novel phosphotyrosine motif mediating STAT1 activation. J Biol Chem. 1996;271:12991-12998.
-
(1996)
J Biol Chem
, vol.271
, pp. 12991-12998
-
-
Gerhartz, C.1
Heesel, B.2
Sasse, J.3
-
39
-
-
0033772398
-
A transient assay for regulatory gene function in haemopoietic progenitor cells
-
McIvor ZJ, Heyworth CM, Johnson BA, et al. A transient assay for regulatory gene function in haemopoietic progenitor cells. Br J Haematol. 2000;110:674-681.
-
(2000)
Br J Haematol
, vol.110
, pp. 674-681
-
-
McIvor, Z.J.1
Heyworth, C.M.2
Johnson, B.A.3
-
40
-
-
0030747461
-
HIV-1 infection of non-dividing cells: Evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import
-
Fouchier RA, Meyer BE, Simon JH, Fischer U, Malim MH. HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import. EMBO J. 1997;16:4531-4539.
-
(1997)
EMBO J
, vol.16
, pp. 4531-4539
-
-
Fouchier, R.A.1
Meyer, B.E.2
Simon, J.H.3
Fischer, U.4
Malim, M.H.5
-
41
-
-
0034628493
-
Development of a self-inactivating, minimal lentivirus vector based on simian immunodeficiency virus
-
Schnell T, Foley P, Wirth M, Munch J, Uberla K. Development of a self-inactivating, minimal lentivirus vector based on simian immunodeficiency virus. Hum Gene Ther. 2000;11:439-447.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 439-447
-
-
Schnell, T.1
Foley, P.2
Wirth, M.3
Munch, J.4
Uberla, K.5
-
42
-
-
0033664286
-
Dissection of the signalling requirements of interleukin-6-stimulated myeloma cell growth
-
French JD, Tschumper RC, Jelinek DF. Dissection of the signalling requirements of interleukin-6-stimulated myeloma cell growth. Acta Oncol. 2000;39:777-781.
-
(2000)
Acta Oncol
, vol.39
, pp. 777-781
-
-
French, J.D.1
Tschumper, R.C.2
Jelinek, D.F.3
-
43
-
-
0037122897
-
An unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cells
-
Grant SL, Hammacher A, Douglas AM, et al. An unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cells. Oncogene. 2002;21:460-474.
-
(2002)
Oncogene
, vol.21
, pp. 460-474
-
-
Grant, S.L.1
Hammacher, A.2
Douglas, A.M.3
-
44
-
-
0029968757
-
Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation
-
Yamanaka Y, Nakajima K, Fukada T, Hibi M, Hirano T. Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation. EMBO J. 1996;15:1557-1565.
-
(1996)
EMBO J
, vol.15
, pp. 1557-1565
-
-
Yamanaka, Y.1
Nakajima, K.2
Fukada, T.3
Hibi, M.4
Hirano, T.5
-
45
-
-
0029812490
-
Interleukin 6 receptor superantagonists are potent inducers of human multiple myeloma cell death
-
Demartis A, Bernassola F, Savino R, Melino G, Ciliberto G. Interleukin 6 receptor superantagonists are potent inducers of human multiple myeloma cell death. Cancer Res. 1996;56:4213-4218.
-
(1996)
Cancer Res
, vol.56
, pp. 4213-4218
-
-
Demartis, A.1
Bernassola, F.2
Savino, R.3
Melino, G.4
Ciliberto, G.5
-
46
-
-
0022499547
-
Complementary DNA for a novel interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin
-
Hirano T, Yasukawa K, Harada H, et al. Complementary DNA for a novel interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature. 1986;324:73-76.
-
(1986)
Nature
, vol.324
, pp. 73-76
-
-
Hirano, T.1
Yasukawa, K.2
Harada, H.3
-
47
-
-
0023849455
-
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
-
Kawano M, Hirano T, Matsuda T, et al. Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas. Nature. 1988;332:83-85.
-
(1988)
Nature
, vol.332
, pp. 83-85
-
-
Kawano, M.1
Hirano, T.2
Matsuda, T.3
-
48
-
-
0035869281
-
Interleukin-6 is a growth factor for nonmalignant human plasmablasts
-
Jego G, Bataille R, Pellat-Deceunynck C. Interleukin-6 is a growth factor for nonmalignant human plasmablasts. Blood. 2001;97:1817-1822.
-
(2001)
Blood
, vol.97
, pp. 1817-1822
-
-
Jego, G.1
Bataille, R.2
Pellat-Deceunynck, C.3
-
49
-
-
0028928641
-
Differentiation of early plasma cells on bone marrow stromal cells requires interleukin-6 for escaping from apoptosis
-
Kawano MM, Mihara K, Huang N, Tsujimoto T, Kuramoto A. Differentiation of early plasma cells on bone marrow stromal cells requires interleukin-6 for escaping from apoptosis. Blood. 1995;85:487-494.
-
(1995)
Blood
, vol.85
, pp. 487-494
-
-
Kawano, M.M.1
Mihara, K.2
Huang, N.3
Tsujimoto, T.4
Kuramoto, A.5
-
50
-
-
0031806534
-
Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase
-
Takahashi-Tezuka M, Yoshida Y, Fukada T, et al. Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase. Mol Cell Biol. 1998;18:4109-4117.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4109-4117
-
-
Takahashi-Tezuka, M.1
Yoshida, Y.2
Fukada, T.3
-
51
-
-
0035158029
-
Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases
-
Schaeffer M, Schneiderbauer M, Weidler S, et al. Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases. Mol Cell Biol. 2001;21:8068-8081.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8068-8081
-
-
Schaeffer, M.1
Schneiderbauer, M.2
Weidler, S.3
-
52
-
-
0141481982
-
Gene profiling of a myeloma cell line reveals similarities and unique signatures among IL-6 response, N-ras activating mutations and co-culture with bone marrow stromal cells
-
Croonquist PA, Linden MA, Zhao F, Van Ness BG. Gene profiling of a myeloma cell line reveals similarities and unique signatures among IL-6 response, N-ras activating mutations and co-culture with bone marrow stromal cells. Blood. 2003;102:2581-2592.
-
(2003)
Blood
, vol.102
, pp. 2581-2592
-
-
Croonquist, P.A.1
Linden, M.A.2
Zhao, F.3
Van Ness, B.G.4
-
53
-
-
0033534562
-
Functional association of Nmi with Stat5 and Stat1 in IL-2-and IFNgamma-mediated signaling
-
Zhu M, John S, Berg M, Leonard WJ. Functional association of Nmi with Stat5 and Stat1 in IL-2-and IFNgamma-mediated signaling. Cell. 1999;96:121-130.
-
(1999)
Cell
, vol.96
, pp. 121-130
-
-
Zhu, M.1
John, S.2
Berg, M.3
Leonard, W.J.4
-
54
-
-
0037023701
-
Cytokine signaling: STATS in plasma membrane rafts
-
Sehgal PB, Guo GG, Shah M, Kumar V, Patel K. Cytokine signaling: STATS in plasma membrane rafts. J Biol Chem. 2002;277:12067-12074.
-
(2002)
J Biol Chem
, vol.277
, pp. 12067-12074
-
-
Sehgal, P.B.1
Guo, G.G.2
Shah, M.3
Kumar, V.4
Patel, K.5
-
55
-
-
0037458621
-
Essential role of caveolae in interleukin-6- and insulin-like growth factor I-triggered Akt-1-mediated survival of multiple myeloma cells
-
Podar K, Tai YT, Cole CE, et al. Essential role of caveolae in interleukin-6- and insulin-like growth factor I-triggered Akt-1-mediated survival of multiple myeloma cells. J Biol Chem. 2003;278:5794-5801.
-
(2003)
J Biol Chem
, vol.278
, pp. 5794-5801
-
-
Podar, K.1
Tai, Y.T.2
Cole, C.E.3
-
56
-
-
0037600741
-
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
-
Yasukawa H, Ohishi M, Mori H, et al. IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat Immunol. 2003;4:551-556.
-
(2003)
Nat Immunol
, vol.4
, pp. 551-556
-
-
Yasukawa, H.1
Ohishi, M.2
Mori, H.3
-
57
-
-
0038614944
-
SOCS3 regulates the plasticity of gp130 signaling
-
Lang R, Pauleau AL, Parganas E, et al. SOCS3 regulates the plasticity of gp130 signaling. Nat Immunol. 2003;4:546-550.
-
(2003)
Nat Immunol
, vol.4
, pp. 546-550
-
-
Lang, R.1
Pauleau, A.L.2
Parganas, E.3
-
58
-
-
0037938816
-
SOCS3 negatively regulates IL-6 signaling in vivo
-
Croker BA, Krebs DL, Zhang JG, et al. SOCS3 negatively regulates IL-6 signaling in vivo. Nat Immunol. 2003;4:540-545.
-
(2003)
Nat Immunol
, vol.4
, pp. 540-545
-
-
Croker, B.A.1
Krebs, D.L.2
Zhang, J.G.3
-
59
-
-
0037085778
-
Myeloid cell factor-1 is a critical survival factor for multiple myeloma
-
Zhang B, Gojo I, Fenton RG. Myeloid cell factor-1 is a critical survival factor for multiple myeloma. Blood. 2002;99:1885-1893.
-
(2002)
Blood
, vol.99
, pp. 1885-1893
-
-
Zhang, B.1
Gojo, I.2
Fenton, R.G.3
-
60
-
-
0033451992
-
Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis
-
Shirogane T, Fukada T, Muller JM, Shima DT, Hibi M, Hirano T. Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis. Immunity. 1999;11:709-719.
-
(1999)
Immunity
, vol.11
, pp. 709-719
-
-
Shirogane, T.1
Fukada, T.2
Muller, J.M.3
Shima, D.T.4
Hibi, M.5
Hirano, T.6
-
61
-
-
0035076453
-
Interleukin-11 up-regulates survivin expression in endothelial cells through a signal transducer and activator of transcription-3 pathway
-
Mahboubi K, Li F, Plescia J, et al. Interleukin-11 up-regulates survivin expression in endothelial cells through a signal transducer and activator of transcription-3 pathway. Lab Invest. 2001;81:327-334.
-
(2001)
Lab Invest
, vol.81
, pp. 327-334
-
-
Mahboubi, K.1
Li, F.2
Plescia, J.3
-
62
-
-
0037441888
-
Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma
-
Aoki Y, Feldman GM, Tosato G. Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma. Blood. 2003;101:1535-1542.
-
(2003)
Blood
, vol.101
, pp. 1535-1542
-
-
Aoki, Y.1
Feldman, G.M.2
Tosato, G.3
-
63
-
-
0035437195
-
Identifying intercellular signaling genes expressed in malignant plasma cells by using complementary DNA arrays
-
De Vos J, Couderc G, Tarte K, et al. Identifying intercellular signaling genes expressed in malignant plasma cells by using complementary DNA arrays. Blood. 2001;98:771-780.
-
(2001)
Blood
, vol.98
, pp. 771-780
-
-
De Vos, J.1
Couderc, G.2
Tarte, K.3
-
64
-
-
0037061757
-
Cooperation between heparin-binding EGF-like growth factor and interleukin-6 in promoting the growth of human myeloma cells
-
Wang YD, De Vos J, Jourdan M, et al. Cooperation between heparin-binding EGF-like growth factor and interleukin-6 in promoting the growth of human myeloma cells. Oncogene. 2002;21:2584-2592.
-
(2002)
Oncogene
, vol.21
, pp. 2584-2592
-
-
Wang, Y.D.1
De Vos, J.2
Jourdan, M.3
-
65
-
-
0037103205
-
Generation of polyclonal plasmablasts from peripheral blood B cells: A normal counterpart of malignant plasmablasts
-
Tarte K, De Vos J, Thykjaer T, et al. Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts. Blood. 2002;100:1113-1122.
-
(2002)
Blood
, vol.100
, pp. 1113-1122
-
-
Tarte, K.1
De Vos, J.2
Thykjaer, T.3
-
66
-
-
0347336379
-
Gas6 induces mesangial cell proliferation via latent transcription factor STAT3
-
Yanagita M, Arai H, Nakano T, et al. Gas6 induces mesangial cell proliferation via latent transcription factor STAT3. J Biol Chem. 2001;276:42364-42369.
-
(2001)
J Biol Chem
, vol.276
, pp. 42364-42369
-
-
Yanagita, M.1
Arai, H.2
Nakano, T.3
-
67
-
-
85009834509
-
CD44 variant isoforms are involved in plasma cell adhesion to bone marrow stromal cells
-
Van Driel M, Gunthert U, van Kessel AC, et al. CD44 variant isoforms are involved in plasma cell adhesion to bone marrow stromal cells. Leukemia. 2002;16:135-143.
-
(2002)
Leukemia
, vol.16
, pp. 135-143
-
-
Van Driel, M.1
Gunthert, U.2
Van Kessel, A.C.3
-
68
-
-
0035824560
-
The osteopontin-CD44 survival signal involves activation of the phosphatidylinositol 3-kinase/Akt signaling pathway
-
Lin YH, Yang-Yen HF. The osteopontin-CD44 survival signal involves activation of the phosphatidylinositol 3-kinase/Akt signaling pathway. J Biol Chem. 2001;276:46024-46030.
-
(2001)
J Biol Chem
, vol.276
, pp. 46024-46030
-
-
Lin, Y.H.1
Yang-Yen, H.F.2
-
70
-
-
0032168362
-
OCA-B integrates B cell antigen receptor-, CD40L- and IL 4-mediated signals for the germinal center pathway of B cell development
-
Qin XF, Reichlin A, Luo Y, Roeder RG, Nussenzweig MC. OCA-B integrates B cell antigen receptor-, CD40L- and IL 4-mediated signals for the germinal center pathway of B cell development. EMBO J. 1998;17:5066-5075.
-
(1998)
EMBO J
, vol.17
, pp. 5066-5075
-
-
Qin, X.F.1
Reichlin, A.2
Luo, Y.3
Roeder, R.G.4
Nussenzweig, M.C.5
-
71
-
-
84984756503
-
Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma
-
Iida S, Rao PH, Butler M, et al. Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma. Nat Genet. 1997;17:226-230.
-
(1997)
Nat Genet
, vol.17
, pp. 226-230
-
-
Iida, S.1
Rao, P.H.2
Butler, M.3
-
72
-
-
0031839633
-
Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma
-
Chesi M, Bergsagel PL, Shonukan OO, et al. Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma. Blood. 1998;91:4457-4463.
-
(1998)
Blood
, vol.91
, pp. 4457-4463
-
-
Chesi, M.1
Bergsagel, P.L.2
Shonukan, O.O.3
-
73
-
-
0027938203
-
Simultaneous activation of Ig and Oct-2 synthesis and reduction of surface MHC class II expression by IL-6
-
Natkunam Y, Zhang X, Liu Z, Chen-Kiang S. Simultaneous activation of Ig and Oct-2 synthesis and reduction of surface MHC class II expression by IL-6. J Immunol. 1994;153:3476-3484.
-
(1994)
J Immunol
, vol.153
, pp. 3476-3484
-
-
Natkunam, Y.1
Zhang, X.2
Liu, Z.3
Chen-Kiang, S.4
-
74
-
-
0033680860
-
BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control
-
Shaffer AL, Yu X, He Y, Boldrick J, Chan EP, Staudt LM. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity. 2000;13:199-212.
-
(2000)
Immunity
, vol.13
, pp. 199-212
-
-
Shaffer, A.L.1
Yu, X.2
He, Y.3
Boldrick, J.4
Chan, E.P.5
Staudt, L.M.6
-
75
-
-
0034684672
-
Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6
-
Reljic R, Wagner SD, Peakman LJ, Fearon DT. Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6. J Exp Med. 2000;192:1841-1848.
-
(2000)
J Exp Med
, vol.192
, pp. 1841-1848
-
-
Reljic, R.1
Wagner, S.D.2
Peakman, L.J.3
Fearon, D.T.4
-
76
-
-
18344389897
-
The human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: Implications for a role of BCL6 in the down-regulation of apoptosis
-
Baron BW, Anastasi J, Thirman MJ, et al. The human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: implications for a role of BCL6 in the down-regulation of apoptosis. Proc Natl Acad Sci U S A. 2002;99:2860-2865.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2860-2865
-
-
Baron, B.W.1
Anastasi, J.2
Thirman, M.J.3
-
77
-
-
18444395232
-
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program
-
Shaffer AL, Lin KI, Kuo TC, et al. Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity. 2002;17:51-62.
-
(2002)
Immunity
, vol.17
, pp. 51-62
-
-
Shaffer, A.L.1
Lin, K.I.2
Kuo, T.C.3
-
78
-
-
0034669911
-
Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo
-
Angelin-Duclos C, Cattoretti G, Lin KI, Calame K. Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo. J Immunol. 2000;165:5462-5471.
-
(2000)
J Immunol
, vol.165
, pp. 5462-5471
-
-
Angelin-Duclos, C.1
Cattoretti, G.2
Lin, K.I.3
Calame, K.4
|