메뉴 건너뛰기




Volumn 67, Issue 2, 2004, Pages 277-284

Effect of vascular endothelial growth factor and epidermal growth factor on iatrogenic apoptosis in human endothelial cells

Author keywords

Apoptosis; EGF; ERKs; PI 3 kinase; Staurosporine; VEGF

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN MCL 1; STAUROSPORINE; VASCULOTROPIN; WORTMANNIN;

EID: 1642579540     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2003.09.007     Document Type: Article
Times cited : (30)

References (42)
  • 1
    • 0031265794 scopus 로고    scopus 로고
    • Biology of the endothelium
    • Lüscher TF, Barton M. Biology of the endothelium. Clin Cardiol 1997; 20 (Suppl II): II-3-10.
    • (1997) Clin Cardiol , vol.20 , Issue.SUPPL II
    • Lüscher, T.F.1    Barton, M.2
  • 2
    • 0033935921 scopus 로고    scopus 로고
    • Apoptosis in the vasculature: Mechanisms and functional importance
    • Mallat Z., Tedgui A. Apoptosis in the vasculature: mechanisms and functional importance. Br. J. Pharmacol. 130:2000;947-962.
    • (2000) Br. J. Pharmacol. , vol.130 , pp. 947-962
    • Mallat, Z.1    Tedgui, A.2
  • 3
    • 0035947753 scopus 로고    scopus 로고
    • Current perspective on the role of apoptosis in atherothrombotic disease
    • Mallat Z., Tedgui A. Current perspective on the role of apoptosis in atherothrombotic disease. Circ. Res. 88:2001;998-1003.
    • (2001) Circ. Res. , vol.88 , pp. 998-1003
    • Mallat, Z.1    Tedgui, A.2
  • 4
    • 0034979275 scopus 로고    scopus 로고
    • Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor
    • Zachary I. Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor. Am. J. Physiol. Cell Physiol. 280:2001;C1375-C1386.
    • (2001) Am. J. Physiol. Cell Physiol. , vol.280
    • Zachary, I.1
  • 6
    • 0028880305 scopus 로고
    • Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation
    • Tauchi H., Kawaishi K., Kimura A., Satow Y. Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation. Cancer Res. 55:1995;5687-5692.
    • (1995) Cancer Res. , vol.55 , pp. 5687-5692
    • Tauchi, H.1    Kawaishi, K.2    Kimura, A.3    Satow, Y.4
  • 7
    • 0031149457 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits endothelial cell apoptosis induced by tumor necrosis factor-α: Balance between growth and death signals
    • Spyridopoulos I., Brogi E., Kearney M., Sullivan A.B., Cetrulo C., Isner J.M., Losordo D.W. Vascular endothelial growth factor inhibits endothelial cell apoptosis induced by tumor necrosis factor-α: balance between growth and death signals. J. Mol. Cell Cardiol. 29:1997;1321-1330.
    • (1997) J. Mol. Cell Cardiol. , vol.29 , pp. 1321-1330
    • Spyridopoulos, I.1    Brogi, E.2    Kearney, M.3    Sullivan, A.B.4    Cetrulo, C.5    Isner, J.M.6    Losordo, D.W.7
  • 8
    • 0032515047 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway
    • Gerber H.P., McMurtrey A., Kowalski J., Yan M., Key B.A., Dixit V., Ferrara N. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. J. Biol. Chem. 273:1998;30336-30343.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30336-30343
    • Gerber, H.P.1    McMurtrey, A.2    Kowalski, J.3    Yan, M.4    Key, B.A.5    Dixit, V.6    Ferrara, N.7
  • 9
    • 0035025911 scopus 로고    scopus 로고
    • VEGF protects against oxidized LDL toxicity to endothelial cells by an intracellular glutathione-dependent mechanism through the KDR receptor
    • Kuzuya M., Ramos M.A., Kanda S., Koike T., Asai T., Maeda K., Shitara K., Shibuya M., Iguchi A. VEGF protects against oxidized LDL toxicity to endothelial cells by an intracellular glutathione-dependent mechanism through the KDR receptor. Arterioscler. Thromb. Vasc. Biol. 21:2001;765-774.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 765-774
    • Kuzuya, M.1    Ramos, M.A.2    Kanda, S.3    Koike, T.4    Asai, T.5    Maeda, K.6    Shitara, K.7    Shibuya, M.8    Iguchi, A.9
  • 10
    • 0032557564 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1
    • Gerber H.P., Dixit V., Ferrara N. Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1. J. Biol. Chem. 273:1998;13313-13316.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13313-13316
    • Gerber, H.P.1    Dixit, V.2    Ferrara, N.3
  • 11
    • 0032403016 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor
    • Katoh O., Takahashi T., Oguri T., Kuramoto K., Mihara K., Kobayashi M., Hirata S., Watanabe H. Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor. Cancer Res. 58:1998;5565-5569.
    • (1998) Cancer Res. , vol.58 , pp. 5565-5569
    • Katoh, O.1    Takahashi, T.2    Oguri, T.3    Kuramoto, K.4    Mihara, K.5    Kobayashi, M.6    Hirata, S.7    Watanabe, H.8
  • 12
    • 0037192824 scopus 로고    scopus 로고
    • Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism
    • Lorenzo E., Ruiz-Ruiz C., Quesada A.J., Hernandez G., Rodriguez A., Lopes-Rivas A., Redondo J.M. Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism. J. Biol. Chem. 277:2002;10883-10892.
    • (2002) J. Biol. Chem. , vol.277 , pp. 10883-10892
    • Lorenzo, E.1    Ruiz-Ruiz, C.2    Quesada, A.J.3    Hernandez, G.4    Rodriguez, A.5    Lopes-Rivas, A.6    Redondo, J.M.7
  • 13
    • 0035476728 scopus 로고    scopus 로고
    • Antimitogenic and proapoptotic activities of methylseleninic acid in vascular endothelial cells and associated effects on PI3K-AKT, ERK, JNK and p38 MAPK signaling
    • Wang Z., Jiang C., Ganther H., Lu J. Antimitogenic and proapoptotic activities of methylseleninic acid in vascular endothelial cells and associated effects on PI3K-AKT, ERK, JNK and p38 MAPK signaling. Cancer Res. 61:2001;7171-7178.
    • (2001) Cancer Res. , vol.61 , pp. 7171-7178
    • Wang, Z.1    Jiang, C.2    Ganther, H.3    Lu, J.4
  • 14
    • 0034013507 scopus 로고    scopus 로고
    • Staurosporine analogues-pharmacological toys or useful antitumour agents?
    • Gesher A. Staurosporine analogues-pharmacological toys or useful antitumour agents? Crit. Rev. Oncol./Hematol. 34:2000;127-135.
    • (2000) Crit. Rev. Oncol./Hematol. , vol.34 , pp. 127-135
    • Gesher, A.1
  • 15
    • 0034704939 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway
    • Leu C.M., Chang C., Hu C. Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway. Oncogene. 19:2000;1665-1675.
    • (2000) Oncogene , vol.19 , pp. 1665-1675
    • Leu, C.M.1    Chang, C.2    Hu, C.3
  • 16
    • 0011694667 scopus 로고
    • Synthesis of von Willebrand factor by cultured human endothelial cells
    • Jaffe E.A., Hoyer L.W., Nachman R.L. Synthesis of von Willebrand factor by cultured human endothelial cells. Proc. Natl. Acad. Sci. U.S.A. 71:1974;1906-1909.
    • (1974) Proc. Natl. Acad. Sci. U.S.A. , vol.71 , pp. 1906-1909
    • Jaffe, E.A.1    Hoyer, L.W.2    Nachman, R.L.3
  • 17
    • 0017277818 scopus 로고
    • Assay of proteins in the presence of interfering materials
    • Bensadoun A., Weinstein D. Assay of proteins in the presence of interfering materials. Anal. Biochem. 70:1976;241-250.
    • (1976) Anal. Biochem. , vol.70 , pp. 241-250
    • Bensadoun, A.1    Weinstein, D.2
  • 18
    • 0030956584 scopus 로고    scopus 로고
    • Apoptotic vascular endothelial cells become procoagulant
    • Bombeli T., Karsan A., Tait J.F., Harlan J.M. Apoptotic vascular endothelial cells become procoagulant. Blood. 7:1997;2429-2442.
    • (1997) Blood , vol.7 , pp. 2429-2442
    • Bombeli, T.1    Karsan, A.2    Tait, J.F.3    Harlan, J.M.4
  • 19
    • 0033574578 scopus 로고    scopus 로고
    • The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotides
    • Ackermann E.J., Taylor J.K., Narayana R., Bennett C. The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotides. J. Biol. Chem. 274:1998;11245-11252.
    • (1998) J. Biol. Chem. , vol.274 , pp. 11245-11252
    • Ackermann, E.J.1    Taylor, J.K.2    Narayana, R.3    Bennett, C.4
  • 20
    • 0034661538 scopus 로고    scopus 로고
    • Protein kinase flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia
    • Kitada S., Zapata J.M., Andreeff M., Reed J.C. Protein kinase flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia. Blood. 96:2000;393-397.
    • (2000) Blood , vol.96 , pp. 393-397
    • Kitada, S.1    Zapata, J.M.2    Andreeff, M.3    Reed, J.C.4
  • 21
    • 0037213368 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Sensors and checkpoints for life-or-death decisions
    • Borner C. The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol. Immunol. 39:2003;615-647.
    • (2003) Mol. Immunol. , vol.39 , pp. 615-647
    • Borner, C.1
  • 22
    • 0033556387 scopus 로고    scopus 로고
    • Regulation of Mcl-1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation
    • Townsend K.J., Zhou P., Qian L., Bieszczad C.K., Lowrey H., Yen A., Craig R.W. Regulation of Mcl-1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation. J. Biol. Chem. 15:1999;1801-1813.
    • (1999) J. Biol. Chem. , vol.15 , pp. 1801-1813
    • Townsend, K.J.1    Zhou, P.2    Qian, L.3    Bieszczad, C.K.4    Lowrey, H.5    Yen, A.6    Craig, R.W.7
  • 23
    • 0036362181 scopus 로고    scopus 로고
    • Why epidermal growth factor receptor? the rationale for cancer therapy
    • Baselga J. Why epidermal growth factor receptor? The rationale for cancer therapy. The Oncologist. 7(Suppl. 4):2002;2-8.
    • (2002) The Oncologist , vol.7 , Issue.SUPPL. 4 , pp. 2-8
    • Baselga, J.1
  • 24
    • 0037036348 scopus 로고    scopus 로고
    • Dose-dependent activation of antiapoptotic and proapoptotic pathways by ethanol treatment in human vascular endothelial cells: Differential involvement of adenosin
    • Liu J., Tian Z., Gao B., Kunos G. Dose-dependent activation of antiapoptotic and proapoptotic pathways by ethanol treatment in human vascular endothelial cells: differential involvement of adenosin. J. Biol. Chem. 277:2002;20927-20933.
    • (2002) J. Biol. Chem. , vol.277 , pp. 20927-20933
    • Liu, J.1    Tian, Z.2    Gao, B.3    Kunos, G.4
  • 25
    • 0028884033 scopus 로고
    • PD098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi D.R., Cuenda A., Cohen P., Dudley D.T., Saltiel A.R. PD098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270:1995;27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 27
    • 0018657510 scopus 로고
    • Mechanisms of glucocorticoid action on immune processes
    • Parillo J.E., Fauci A.S. Mechanisms of glucocorticoid action on immune processes. Ann. Rev. Pharmacol. Toxicol. 19:1979;179.
    • (1979) Ann. Rev. Pharmacol. Toxicol. , vol.19 , pp. 179
    • Parillo, J.E.1    Fauci, A.S.2
  • 29
    • 0036778552 scopus 로고    scopus 로고
    • NCX-4016, a nitric oxide-releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function
    • Fiorucci S., Mencarelli A., Manucci R., Distrutti E., Morelli A., del Soldato P. NCX-4016, a nitric oxide-releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function. FASEB J. 16:2002;1645-1647.
    • (2002) FASEB J. , vol.16 , pp. 1645-1647
    • Fiorucci, S.1    Mencarelli, A.2    Manucci, R.3    Distrutti, E.4    Morelli, A.5    Del Soldato, P.6
  • 30
    • 0035826163 scopus 로고    scopus 로고
    • Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation
    • Stepczynska A., Lauber K., Engels I.H., Janssen O., Kabelitz D., Wesselborg S., Schulze-Osthoff K. Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation. Oncogene. 20:2001;1193-1202.
    • (2001) Oncogene , vol.20 , pp. 1193-1202
    • Stepczynska, A.1    Lauber, K.2    Engels, I.H.3    Janssen, O.4    Kabelitz, D.5    Wesselborg, S.6    Schulze-Osthoff, K.7
  • 31
    • 0035821647 scopus 로고    scopus 로고
    • Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms
    • Belmokhtar C.A., Hillion J., Ségal-Bendirdjian E. Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms. Oncogene. 20:2001;3354-3362.
    • (2001) Oncogene , vol.20 , pp. 3354-3362
    • Belmokhtar, C.A.1    Hillion, J.2    Ségal-Bendirdjian, E.3
  • 32
    • 0033004572 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and protein kinase C are required for the inhibition of caspase activity by epidermal growth factor
    • Lan L., Wong N.S. Phosphatidylinositol 3-kinase and protein kinase C are required for the inhibition of caspase activity by epidermal growth factor. FEBS Lett. 444:1999;90-96.
    • (1999) FEBS Lett. , vol.444 , pp. 90-96
    • Lan, L.1    Wong, N.S.2
  • 34
    • 0031882017 scopus 로고    scopus 로고
    • Cyclic AMP protects against staurosporine and wortmannin-induced apoptosis and opioid-enhanced apoptosis in both embryonic and immortalized (F-11kappa7) neurons
    • Goswami R., Dawson S.A., Dawson G. Cyclic AMP protects against staurosporine and wortmannin-induced apoptosis and opioid-enhanced apoptosis in both embryonic and immortalized (F-11kappa7) neurons. J. Neurochem. 70:1998;1376-1382.
    • (1998) J. Neurochem. , vol.70 , pp. 1376-1382
    • Goswami, R.1    Dawson, S.A.2    Dawson, G.3
  • 35
    • 0034681392 scopus 로고    scopus 로고
    • Utilization of distinct signaling pathway by receptors for vascular endothelial cell growth factor and other mitogen in the induction of endothelial cell proliferation
    • Wu L.W., Mayo L.D., Dunbar J.D., Kessler K.M., Baerwald M.R., Jaffe E.A., Wang D., Warren R.S., Donner D.B. Utilization of distinct signaling pathway by receptors for vascular endothelial cell growth factor and other mitogen in the induction of endothelial cell proliferation. J. Biol. Chem. 275:2000;5096-5103.
    • (2000) J. Biol. Chem. , vol.275 , pp. 5096-5103
    • Wu, L.W.1    Mayo, L.D.2    Dunbar, J.D.3    Kessler, K.M.4    Baerwald, M.R.5    Jaffe, E.A.6    Wang, D.7    Warren, R.S.8    Donner, D.B.9
  • 36
    • 0031815977 scopus 로고    scopus 로고
    • Molecular biology of chronic lymphocytic leukaemia: Implications for therapy
    • Reed J.C. Molecular biology of chronic lymphocytic leukaemia: implications for therapy. Semin. Hematol. 35:1998;3-13.
    • (1998) Semin. Hematol. , vol.35 , pp. 3-13
    • Reed, J.C.1
  • 37
    • 0029906431 scopus 로고    scopus 로고
    • BCL-2 and MCL-1 expression in Chinese hamster ovary cells inhibits intracellular acidification and apoptosis induced by staurosporine
    • Reynolds J.E., Li J., Craig R.W., Eastman A. BCL-2 and MCL-1 expression in Chinese hamster ovary cells inhibits intracellular acidification and apoptosis induced by staurosporine. Exp. Cell Res. 225:1996;430-436.
    • (1996) Exp. Cell Res. , vol.225 , pp. 430-436
    • Reynolds, J.E.1    Li, J.2    Craig, R.W.3    Eastman, A.4
  • 38
    • 0036289544 scopus 로고    scopus 로고
    • Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death
    • Araki T., Hayashi M., Watanabe N., Kanuka H., Yoshino J., Miura M., Saruta T. Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death. Biochem. Biophys. Res. Commun. 290:2002;1275-1281.
    • (2002) Biochem. Biophys. Res. Commun. , vol.290 , pp. 1275-1281
    • Araki, T.1    Hayashi, M.2    Watanabe, N.3    Kanuka, H.4    Yoshino, J.5    Miura, M.6    Saruta, T.7
  • 39
    • 0035825596 scopus 로고    scopus 로고
    • The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6
    • Kuo M.L., Chuang S.E., Lin M.T., Yang S.Y. The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6. Oncogene. 20:2001;677-685.
    • (2001) Oncogene , vol.20 , pp. 677-685
    • Kuo, M.L.1    Chuang, S.E.2    Lin, M.T.3    Yang, S.Y.4
  • 40
    • 0032772367 scopus 로고    scopus 로고
    • The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB
    • Wang J.M., Chao J.R., Chen W., Kuo M.L., Yen J.J.-Y., Yang-Yen H.F. The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB. Mol. Cell Biol. 19:1999;6195-6206.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 6195-6206
    • Wang, J.M.1    Chao, J.R.2    Chen, W.3    Kuo, M.L.4    Yen, J.J.-Y.5    Yang-Yen, H.F.6
  • 41
    • 0034618369 scopus 로고    scopus 로고
    • MEK/ERK signalling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells
    • Boucher M.J., Morisset J., Vachon P.H., Reed J.C., Laine J., Rivard N. MEK/ERK signalling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells. J. Cell Biochem. 79:2000;355-369.
    • (2000) J. Cell Biochem. , vol.79 , pp. 355-369
    • Boucher, M.J.1    Morisset, J.2    Vachon, P.H.3    Reed, J.C.4    Laine, J.5    Rivard, N.6
  • 42
    • 0034284309 scopus 로고    scopus 로고
    • Mcl-1 is a common target of stem cell factor and interleukin-5 for apoptosis prevention activity via MEK/MAPK and PI-3K/Akt pathways
    • Huang H.M., Huang C.J., Yen J.J. Mcl-1 is a common target of stem cell factor and interleukin-5 for apoptosis prevention activity via MEK/MAPK and PI-3K/Akt pathways. Blood. 96:2000;1764-1771.
    • (2000) Blood , vol.96 , pp. 1764-1771
    • Huang, H.M.1    Huang, C.J.2    Yen, J.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.