-
1
-
-
17444420714
-
Subversion mechanisms by which Leishmania parasites can escape the host immune response: a signaling point of view
-
Olivier M., Gregory D.J., and Forget G. Subversion mechanisms by which Leishmania parasites can escape the host immune response: a signaling point of view. Clin. Microbiol. Rev. 18 (2005) 293-305
-
(2005)
Clin. Microbiol. Rev.
, vol.18
, pp. 293-305
-
-
Olivier, M.1
Gregory, D.J.2
Forget, G.3
-
2
-
-
0032991895
-
How do protozoan parasites survive inside macrophages?
-
Bogdan C., and Rollinghoff M. How do protozoan parasites survive inside macrophages?. Parasitol. Today 15 (1999) 22-28
-
(1999)
Parasitol. Today
, vol.15
, pp. 22-28
-
-
Bogdan, C.1
Rollinghoff, M.2
-
3
-
-
0034255209
-
Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens
-
Nathan C., and Shiloh M.U. Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. Proc. Natl. Acad. Sci. USA 97 (2000) 8841-8848
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 8841-8848
-
-
Nathan, C.1
Shiloh, M.U.2
-
4
-
-
0036853070
-
Evasion of innate immunity by parasitic protozoa
-
Sacks D., and Sher A. Evasion of innate immunity by parasitic protozoa. Nat. Immunol. 3 (2002) 1041-1047
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1041-1047
-
-
Sacks, D.1
Sher, A.2
-
5
-
-
0019471126
-
Susceptibility of Leishmania to oxygen intermediates and killing by normal macrophages
-
Murray H.W. Susceptibility of Leishmania to oxygen intermediates and killing by normal macrophages. J. Exp. Med. 153 (1981) 1302-1315
-
(1981)
J. Exp. Med.
, vol.153
, pp. 1302-1315
-
-
Murray, H.W.1
-
6
-
-
0025300228
-
Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine
-
Liew F.Y., Millott S., Parkinson C., Palmer R.M., and Moncada S. Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine. J. Immunol. 144 (1990) 4794-4797
-
(1990)
J. Immunol.
, vol.144
, pp. 4794-4797
-
-
Liew, F.Y.1
Millott, S.2
Parkinson, C.3
Palmer, R.M.4
Moncada, S.5
-
7
-
-
0033557291
-
Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani
-
Murray H.W., and Nathan C.F. Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani. J. Exp. Med. 189 (1999) 741-746
-
(1999)
J. Exp. Med.
, vol.189
, pp. 741-746
-
-
Murray, H.W.1
Nathan, C.F.2
-
8
-
-
0035879106
-
Oxidative responses of human and murine macrophages during phagocytosis of Leishmania chagasi
-
Gantt K.R., Goldman T.L., McCormick M.L., Miller M.A., Jeronimo S.M., Nascimento E.T., Britigan B.E., and Wilson M.E. Oxidative responses of human and murine macrophages during phagocytosis of Leishmania chagasi. J. Immunol. 167 (2001) 893-901
-
(2001)
J. Immunol.
, vol.167
, pp. 893-901
-
-
Gantt, K.R.1
Goldman, T.L.2
McCormick, M.L.3
Miller, M.A.4
Jeronimo, S.M.5
Nascimento, E.T.6
Britigan, B.E.7
Wilson, M.E.8
-
9
-
-
34249669128
-
Macrophage killing of Leishmania amazonensis amastigotes requires both nitric oxide and superoxide
-
Mukbel R.M., Patten Jr. C., Gibson K., Ghosh M., Petersen C., and Jones D.E. Macrophage killing of Leishmania amazonensis amastigotes requires both nitric oxide and superoxide. Am. J. Trop. Med. Hyg. 76 (2007) 669-675
-
(2007)
Am. J. Trop. Med. Hyg.
, vol.76
, pp. 669-675
-
-
Mukbel, R.M.1
Patten Jr., C.2
Gibson, K.3
Ghosh, M.4
Petersen, C.5
Jones, D.E.6
-
10
-
-
0026693720
-
Defective stimulus-response coupling in human monocytes infected with Leishmania donovani is associated with altered activation and translocation of protein kinase C
-
Olivier M., Brownsey R.W., and Reiner N.E. Defective stimulus-response coupling in human monocytes infected with Leishmania donovani is associated with altered activation and translocation of protein kinase C. Proc. Natl. Acad. Sci. USA 89 (1992) 7481-7485
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7481-7485
-
-
Olivier, M.1
Brownsey, R.W.2
Reiner, N.E.3
-
11
-
-
0027284773
-
Alteration of Leishmania donovani infection levels by selective impairment of macrophage signal transduction
-
Moore K.J., Labrecque S., and Matlashewski G. Alteration of Leishmania donovani infection levels by selective impairment of macrophage signal transduction. J. Immunol. 150 (1993) 4457-4465
-
(1993)
J. Immunol.
, vol.150
, pp. 4457-4465
-
-
Moore, K.J.1
Labrecque, S.2
Matlashewski, G.3
-
12
-
-
0022002912
-
Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids
-
Fairlamb A.H., Blackburn P., Ulrich P., Chait B.T., and Cerami A. Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids. Science 227 (1985) 1485-1487
-
(1985)
Science
, vol.227
, pp. 1485-1487
-
-
Fairlamb, A.H.1
Blackburn, P.2
Ulrich, P.3
Chait, B.T.4
Cerami, A.5
-
13
-
-
0027990965
-
Thiols of intracellular pathogens: identification of ovothiol A in Leishmania donovani and structural analysis of a novel thiol from Mycobacterium bovis
-
Spies H.S., and Steenkamp D.J. Thiols of intracellular pathogens: identification of ovothiol A in Leishmania donovani and structural analysis of a novel thiol from Mycobacterium bovis. Eur. J. Biochem. 224 (1994) 203-213
-
(1994)
Eur. J. Biochem.
, vol.224
, pp. 203-213
-
-
Spies, H.S.1
Steenkamp, D.J.2
-
14
-
-
0035400398
-
Ovothiol and trypanothione as antioxidants in trypanosomatids
-
Ariyanayagam M.R., and Fairlamb A.H. Ovothiol and trypanothione as antioxidants in trypanosomatids. Mol. Biochem. Parasitol. 115 (2001) 189-198
-
(2001)
Mol. Biochem. Parasitol.
, vol.115
, pp. 189-198
-
-
Ariyanayagam, M.R.1
Fairlamb, A.H.2
-
16
-
-
54949087530
-
Insights into the redox biology of Trypanosoma cruzi: trypanothione metabolism and oxidant detoxification
-
Irigoin F., Cibils L., Comini M.A., Wilkinson S.R., Flohé L., and Radi R. Insights into the redox biology of Trypanosoma cruzi: trypanothione metabolism and oxidant detoxification. Free Radic. Biol. Med. 45 (2008) 733-742
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 733-742
-
-
Irigoin, F.1
Cibils, L.2
Comini, M.A.3
Wilkinson, S.R.4
Flohé, L.5
Radi, R.6
-
17
-
-
0037518119
-
Role of peroxidoxins in Leishmania chagasi survival: evidence of an enzymatic defense against nitrosative stress
-
Barr S.D., and Gedamu L. Role of peroxidoxins in Leishmania chagasi survival: evidence of an enzymatic defense against nitrosative stress. J. Biol. Chem. 278 (2003) 10816-10823
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10816-10823
-
-
Barr, S.D.1
Gedamu, L.2
-
18
-
-
0141557631
-
Iron superoxide dismutases targeted to the glycosomes of Leishmania chagasi are important for survival
-
Plewes K.A., Barr S.D., and Gedamu L. Iron superoxide dismutases targeted to the glycosomes of Leishmania chagasi are important for survival. Infect. Immun. 71 (2003) 5910-5920
-
(2003)
Infect. Immun.
, vol.71
, pp. 5910-5920
-
-
Plewes, K.A.1
Barr, S.D.2
Gedamu, L.3
-
19
-
-
30344437302
-
Functional characterisation of the iron superoxide dismutase gene repertoire in Trypanosoma brucei
-
Wilkinson S.R., Prathalingam S.R., Taylor M.C., Ahmed A., Horn D., and Kelly J.M. Functional characterisation of the iron superoxide dismutase gene repertoire in Trypanosoma brucei. Free Radic. Biol. Med. 40 (2006) 198-209
-
(2006)
Free Radic. Biol. Med.
, vol.40
, pp. 198-209
-
-
Wilkinson, S.R.1
Prathalingam, S.R.2
Taylor, M.C.3
Ahmed, A.4
Horn, D.5
Kelly, J.M.6
-
20
-
-
0343775483
-
Microbial glycolipids: possible virulence factors that scavenge oxygen radicals
-
Chan J., Fujiwara T., Brennan P., McNeil M., Turco S.J., Sibille J.C., Snapper M., Aisen P., and Bloom B.R. Microbial glycolipids: possible virulence factors that scavenge oxygen radicals. Proc. Natl. Acad. Sci. USA 86 (1989) 2453-2457
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 2453-2457
-
-
Chan, J.1
Fujiwara, T.2
Brennan, P.3
McNeil, M.4
Turco, S.J.5
Sibille, J.C.6
Snapper, M.7
Aisen, P.8
Bloom, B.R.9
-
21
-
-
0043180475
-
The role(s) of lipophosphoglycan (LPG) in the establishment of Leishmania major infections in mammalian hosts
-
Spath G.F., Garraway L.A., Turco S.J., and Beverley S.M. The role(s) of lipophosphoglycan (LPG) in the establishment of Leishmania major infections in mammalian hosts. Proc. Natl. Acad. Sci. USA 100 (2003) 9536-9541
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 9536-9541
-
-
Spath, G.F.1
Garraway, L.A.2
Turco, S.J.3
Beverley, S.M.4
-
22
-
-
33750611352
-
Leishmania donovani lipophosphoglycan blocks NADPH oxidase assembly at the phagosome membrane
-
Lodge R., Diallo T.O., and Descoteaux A. Leishmania donovani lipophosphoglycan blocks NADPH oxidase assembly at the phagosome membrane. Cell. Microbiol. 8 (2006) 1922-1931
-
(2006)
Cell. Microbiol.
, vol.8
, pp. 1922-1931
-
-
Lodge, R.1
Diallo, T.O.2
Descoteaux, A.3
-
23
-
-
0034721804
-
Inducible resistance to oxidant stress in the protozoan Leishmania chagasi
-
Miller M.A., McGowan S.E., Gantt K.R., Champion M., Novick S.L., Andersen K.A., Bacchi C.J., Yarlett N., Britigan B.E., and Wilson M.E. Inducible resistance to oxidant stress in the protozoan Leishmania chagasi. J. Biol. Chem. 275 (2000) 33883-33889
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33883-33889
-
-
Miller, M.A.1
McGowan, S.E.2
Gantt, K.R.3
Champion, M.4
Novick, S.L.5
Andersen, K.A.6
Bacchi, C.J.7
Yarlett, N.8
Britigan, B.E.9
Wilson, M.E.10
-
24
-
-
0242698082
-
Increased transport of pteridines compensates for mutations in the high affinity folate transporter and contributes to methotrexate resistance in the protozoan parasite Leishmania tarentolae
-
Kündig C., Haimeur A., Légaré D., Papadopoulou B., and Ouellette M. Increased transport of pteridines compensates for mutations in the high affinity folate transporter and contributes to methotrexate resistance in the protozoan parasite Leishmania tarentolae. EMBO J. 18 (1999) 2342-2351
-
(1999)
EMBO J.
, vol.18
, pp. 2342-2351
-
-
Kündig, C.1
Haimeur, A.2
Légaré, D.3
Papadopoulou, B.4
Ouellette, M.5
-
25
-
-
0032725014
-
The Leishmania donovani LD1 locus gene ORFG encodes a biopterin transporter (BT1)
-
Lemley C., Yan S., Dole V.S., Madhubala R., Cunningham M.L., Beverley S.M., Myler P.J., and Stuart K.D. The Leishmania donovani LD1 locus gene ORFG encodes a biopterin transporter (BT1). Mol. Biochem. Parasitol. 104 (1999) 93-105
-
(1999)
Mol. Biochem. Parasitol.
, vol.104
, pp. 93-105
-
-
Lemley, C.1
Yan, S.2
Dole, V.S.3
Madhubala, R.4
Cunningham, M.L.5
Beverley, S.M.6
Myler, P.J.7
Stuart, K.D.8
-
26
-
-
0030946111
-
The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major
-
Nare B., Hardy L.W., and Beverley S.M. The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major. J. Biol. Chem. 272 (1997) 13883-13891
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13883-13891
-
-
Nare, B.1
Hardy, L.W.2
Beverley, S.M.3
-
27
-
-
0031570732
-
Pterin and folate reduction by the Leishmania tarentolae H locus short-chain dehydrogenase/reductase PTR1
-
Wang J., Leblanc E., Chang C.F., Papadopoulou B., Bray T., Whiteley J.M., Lin S.X., and Ouellette M. Pterin and folate reduction by the Leishmania tarentolae H locus short-chain dehydrogenase/reductase PTR1. Arch. Biochem. Biophys. 342 (1997) 197-202
-
(1997)
Arch. Biochem. Biophys.
, vol.342
, pp. 197-202
-
-
Wang, J.1
Leblanc, E.2
Chang, C.F.3
Papadopoulou, B.4
Bray, T.5
Whiteley, J.M.6
Lin, S.X.7
Ouellette, M.8
-
28
-
-
0037064086
-
Characterization of quinonoid-dihydropteridine reductase (QDPR) from the lower eukaryote Leishmania major
-
Lye L.F., Cunningham M.L., and Beverley S.M. Characterization of quinonoid-dihydropteridine reductase (QDPR) from the lower eukaryote Leishmania major. J. Biol. Chem. 277 (2002) 38245-38253
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38245-38253
-
-
Lye, L.F.1
Cunningham, M.L.2
Beverley, S.M.3
-
29
-
-
0034176921
-
Tetrahydrobiopterin biosynthesis, regeneration and functions
-
Thony B., Auerbach G., and Blau N. Tetrahydrobiopterin biosynthesis, regeneration and functions. Biochem. J. 347 Pt 1 (2000) 1-16
-
(2000)
Biochem. J.
, vol.347
, Issue.PART 1
, pp. 1-16
-
-
Thony, B.1
Auerbach, G.2
Blau, N.3
-
30
-
-
0014512078
-
Pteridine requirement of the hemoflagellate Leishmania tarentolae
-
Trager W. Pteridine requirement of the hemoflagellate Leishmania tarentolae. J. Protozool. 16 (1969) 372-375
-
(1969)
J. Protozool.
, vol.16
, pp. 372-375
-
-
Trager, W.1
-
31
-
-
0027996240
-
PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major
-
Bello A.R., Nare B., Freedman D., Hardy L., and Beverley S.M. PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major. Proc. Natl. Acad. Sci. USA 91 (1994) 11442-11446
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11442-11446
-
-
Bello, A.R.1
Nare, B.2
Freedman, D.3
Hardy, L.4
Beverley, S.M.5
-
32
-
-
0028308557
-
Changes in folate and pterin metabolism after disruption of the Leishmania H locus short chain dehydrogenase gene
-
Papadopoulou B., Roy G., Mourad W., Leblanc E., and Ouellette M. Changes in folate and pterin metabolism after disruption of the Leishmania H locus short chain dehydrogenase gene. J. Biol. Chem. 269 (1994) 7310-7315
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 7310-7315
-
-
Papadopoulou, B.1
Roy, G.2
Mourad, W.3
Leblanc, E.4
Ouellette, M.5
-
33
-
-
0034781171
-
Adaptation of Leishmania cells to in vitro culture results in a more efficient reduction and transport of biopterin
-
Roy G., Kundig C., Olivier M., Papadopoulou B., and Ouellette M. Adaptation of Leishmania cells to in vitro culture results in a more efficient reduction and transport of biopterin. Exp. Parasitol. 97 (2001) 161-168
-
(2001)
Exp. Parasitol.
, vol.97
, pp. 161-168
-
-
Roy, G.1
Kundig, C.2
Olivier, M.3
Papadopoulou, B.4
Ouellette, M.5
-
34
-
-
0036225777
-
Tetrahydrobiopterin biosynthesis, utilization and pharmacological effects
-
Werner-Felmayer G., Golderer G., and Werner E.R. Tetrahydrobiopterin biosynthesis, utilization and pharmacological effects. Curr. Drug Metab. 3 (2002) 159-173
-
(2002)
Curr. Drug Metab.
, vol.3
, pp. 159-173
-
-
Werner-Felmayer, G.1
Golderer, G.2
Werner, E.R.3
-
35
-
-
0030921824
-
New approaches to Leishmania chemotherapy: pteridine reductase 1 (PTR1) as a target and modulator of antifolate sensitivity
-
Nare B., Luba J., Hardy L.W., and Beverley S. New approaches to Leishmania chemotherapy: pteridine reductase 1 (PTR1) as a target and modulator of antifolate sensitivity. Parasitology 114 Suppl. (1997) S101-110
-
(1997)
Parasitology
, vol.114
, Issue.SUPPL
-
-
Nare, B.1
Luba, J.2
Hardy, L.W.3
Beverley, S.4
-
36
-
-
0036176478
-
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites
-
Ouellette M., Drummelsmith J., El Fadili A., Kundig C., Richard D., and Roy G. Pterin transport and metabolism in Leishmania and related trypanosomatid parasites. Int. J. Parasitol. 32 (2002) 385-398
-
(2002)
Int. J. Parasitol.
, vol.32
, pp. 385-398
-
-
Ouellette, M.1
Drummelsmith, J.2
El Fadili, A.3
Kundig, C.4
Richard, D.5
Roy, G.6
-
37
-
-
0035853522
-
Regulation of differentiation to the infective stage of the protozoan parasite Leishmania major by tetrahydrobiopterin
-
Cunningham M.L., Titus R.G., Turco S.J., and Beverley S.M. Regulation of differentiation to the infective stage of the protozoan parasite Leishmania major by tetrahydrobiopterin. Science 292 (2001) 285-287
-
(2001)
Science
, vol.292
, pp. 285-287
-
-
Cunningham, M.L.1
Titus, R.G.2
Turco, S.J.3
Beverley, S.M.4
-
38
-
-
0036223478
-
Pteridine derivatives as modulators of oxidative stress
-
Oettl K., and Reibnegger G. Pteridine derivatives as modulators of oxidative stress. Curr. Drug Metab. 3 (2002) 203-209
-
(2002)
Curr. Drug Metab.
, vol.3
, pp. 203-209
-
-
Oettl, K.1
Reibnegger, G.2
-
39
-
-
0037898947
-
Tetrahydrobiopterin radical enzymology
-
Wei C.C., Crane B.R., and Stuehr D.J. Tetrahydrobiopterin radical enzymology. Chem. Rev. 103 (2003) 2365-2383
-
(2003)
Chem. Rev.
, vol.103
, pp. 2365-2383
-
-
Wei, C.C.1
Crane, B.R.2
Stuehr, D.J.3
-
40
-
-
34249282381
-
(6R)-5,6,7,8-tetrahydro-l-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm
-
Mayahi L., Heales S., Owen D., Casas J.P., Harris J., MacAllister R.J., and Hingorani A.D. (6R)-5,6,7,8-tetrahydro-l-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm. Arterioscler. Thromb. Vasc. Biol. 27 (2007) 1334-1339
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, pp. 1334-1339
-
-
Mayahi, L.1
Heales, S.2
Owen, D.3
Casas, J.P.4
Harris, J.5
MacAllister, R.J.6
Hingorani, A.D.7
-
41
-
-
0025321675
-
The amplified H circle of methotrexate-resistant Leishmania tarentolae contains a novel P-glycoprotein gene
-
Ouellette M., Fase-Fowler F., and Borst P. The amplified H circle of methotrexate-resistant Leishmania tarentolae contains a novel P-glycoprotein gene. EMBO J. 9 (1990) 1027-1033
-
(1990)
EMBO J.
, vol.9
, pp. 1027-1033
-
-
Ouellette, M.1
Fase-Fowler, F.2
Borst, P.3
-
44
-
-
0026779424
-
A novel antifolate resistance gene on the amplified H circle of Leishmania
-
Papadopoulou B., Roy G., and Ouellette M. A novel antifolate resistance gene on the amplified H circle of Leishmania. EMBO J. 11 (1992) 3601-3608
-
(1992)
EMBO J.
, vol.11
, pp. 3601-3608
-
-
Papadopoulou, B.1
Roy, G.2
Ouellette, M.3
-
45
-
-
0021889262
-
Identification of cell surface carbohydrate and antigenic changes between noninfective and infective developmental stages of Leishmania major promastigotes
-
Sacks D.L., Hieny S., and Sher A. Identification of cell surface carbohydrate and antigenic changes between noninfective and infective developmental stages of Leishmania major promastigotes. J. Immunol. 135 (1985) 564-569
-
(1985)
J. Immunol.
, vol.135
, pp. 564-569
-
-
Sacks, D.L.1
Hieny, S.2
Sher, A.3
-
46
-
-
0001509578
-
Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide
-
Stuehr D.J., and Marletta M.A. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc. Natl. Acad. Sci. USA 82 (1985) 7738-7742
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 7738-7742
-
-
Stuehr, D.J.1
Marletta, M.A.2
-
47
-
-
0027459588
-
Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing: molecular basis for the synergy between interferon-gamma and lipopolysaccharide
-
Lorsbach R.B., Murphy W.J., Lowenstein C.J., Snyder S.H., and Russell S.W. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing: molecular basis for the synergy between interferon-gamma and lipopolysaccharide. J. Biol. Chem. 268 (1993) 1908-1913
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 1908-1913
-
-
Lorsbach, R.B.1
Murphy, W.J.2
Lowenstein, C.J.3
Snyder, S.H.4
Russell, S.W.5
-
48
-
-
0038604277
-
Phagocytosis of serum- and IgG-opsonized zymosan particles induces apoptosis through superoxide but not nitric oxide in macrophage J774A.1
-
Kim J.S., Kwon H.Y., Choi W.H., Jeon C.Y., Kim J.I., Kim J., Lee J.Y., Kim Y.S., and Park J.B. Phagocytosis of serum- and IgG-opsonized zymosan particles induces apoptosis through superoxide but not nitric oxide in macrophage J774A.1. Exp. Mol. Med. 35 (2003) 211-221
-
(2003)
Exp. Mol. Med.
, vol.35
, pp. 211-221
-
-
Kim, J.S.1
Kwon, H.Y.2
Choi, W.H.3
Jeon, C.Y.4
Kim, J.I.5
Kim, J.6
Lee, J.Y.7
Kim, Y.S.8
Park, J.B.9
-
49
-
-
0027417221
-
An automated micro-fluorometric assay for monitoring oxidative burst activity of phagocytes
-
Wan C.P., Myung E., and Lau B.H. An automated micro-fluorometric assay for monitoring oxidative burst activity of phagocytes. J. Immunol. Methods 159 (1993) 131-138
-
(1993)
J. Immunol. Methods
, vol.159
, pp. 131-138
-
-
Wan, C.P.1
Myung, E.2
Lau, B.H.3
-
50
-
-
0000662562
-
On a new series of bodies in which nitrogen is substituted for hydrogen
-
Griess J. On a new series of bodies in which nitrogen is substituted for hydrogen. Philos. Trans. R. Soc. London 154 (1864) 667-731
-
(1864)
Philos. Trans. R. Soc. London
, vol.154
, pp. 667-731
-
-
Griess, J.1
-
51
-
-
0033747235
-
Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models
-
Roy G., Dumas C., Sereno D., Wu Y., Singh A.K., Tremblay M.J., Ouellette M., Olivier M., and Papadopoulou B. Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models. Mol. Biochem. Parasitol. 110 (2000) 195-206
-
(2000)
Mol. Biochem. Parasitol.
, vol.110
, pp. 195-206
-
-
Roy, G.1
Dumas, C.2
Sereno, D.3
Wu, Y.4
Singh, A.K.5
Tremblay, M.J.6
Ouellette, M.7
Olivier, M.8
Papadopoulou, B.9
-
52
-
-
0035077738
-
DNA transformation of Leishmania infantum axenic amastigotes and their use in drug screening
-
Sereno D., Roy G., Lemesre J.L., Papadopoulou B., and Ouellette M. DNA transformation of Leishmania infantum axenic amastigotes and their use in drug screening. Antimicrob. Agents Chemother. 45 (2001) 1168-1173
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 1168-1173
-
-
Sereno, D.1
Roy, G.2
Lemesre, J.L.3
Papadopoulou, B.4
Ouellette, M.5
-
53
-
-
38649093020
-
Modulation of gene expression in human macrophages treated with the anti-Leishmania pentavalent antimonial drug sodium stibogluconate
-
El Fadili K., Imbeault M., Messier N., Roy G., Gourbal B., Bergeron M., Tremblay M.J., Legare D., and Ouellette M. Modulation of gene expression in human macrophages treated with the anti-Leishmania pentavalent antimonial drug sodium stibogluconate. Antimicrob. Agents Chemother. 52 (2008) 526-533
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 526-533
-
-
El Fadili, K.1
Imbeault, M.2
Messier, N.3
Roy, G.4
Gourbal, B.5
Bergeron, M.6
Tremblay, M.J.7
Legare, D.8
Ouellette, M.9
-
54
-
-
0033517749
-
Fluorescent indicators for imaging nitric oxide production
-
Kojima H., Urano Y., Kikuchi K., Higuchi T., Hirata Y., and Nagano T. Fluorescent indicators for imaging nitric oxide production. Angew. Chem. Int. Ed. Engl. 38 (1999) 3209-3212
-
(1999)
Angew. Chem. Int. Ed. Engl.
, vol.38
, pp. 3209-3212
-
-
Kojima, H.1
Urano, Y.2
Kikuchi, K.3
Higuchi, T.4
Hirata, Y.5
Nagano, T.6
-
55
-
-
2442502624
-
Inactivation of the Leishmania tarentolae pterin transporter (BT1) and reductase (PTR1) genes leads to viable parasites with changes in folate metabolism and hypersensitivity to the antifolate methotrexate
-
El Fadili A., Kundig C., Roy G., and Ouellette M. Inactivation of the Leishmania tarentolae pterin transporter (BT1) and reductase (PTR1) genes leads to viable parasites with changes in folate metabolism and hypersensitivity to the antifolate methotrexate. J. Biol. Chem. 279 (2004) 18575-18582
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18575-18582
-
-
El Fadili, A.1
Kundig, C.2
Roy, G.3
Ouellette, M.4
-
56
-
-
0026459643
-
A member of the aldoketo reductase family confers methotrexate resistance in Leishmania
-
Callahan H.L., and Beverley S.M. A member of the aldoketo reductase family confers methotrexate resistance in Leishmania. J. Biol. Chem. 267 (1992) 24165-24168
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 24165-24168
-
-
Callahan, H.L.1
Beverley, S.M.2
-
57
-
-
4344576960
-
Camptothecin induced mitochondrial dysfunction leading to programmed cell death in unicellular hemoflagellate Leishmania donovani
-
Sen N., Das B.B., Ganguly A., Mukherjee T., Tripathi G., Bandyopadhyay S., Rakshit S., Sen T., and Majumder H.K. Camptothecin induced mitochondrial dysfunction leading to programmed cell death in unicellular hemoflagellate Leishmania donovani. Cell Death Differ. 11 (2004) 924-936
-
(2004)
Cell Death Differ.
, vol.11
, pp. 924-936
-
-
Sen, N.1
Das, B.B.2
Ganguly, A.3
Mukherjee, T.4
Tripathi, G.5
Bandyopadhyay, S.6
Rakshit, S.7
Sen, T.8
Majumder, H.K.9
-
58
-
-
34948899791
-
Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony
-
Mandal G., Wyllie S., Singh N., Sundar S., Fairlamb A.H., and Chatterjee M. Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony. Parasitology 134 (2007) 1679-1687
-
(2007)
Parasitology
, vol.134
, pp. 1679-1687
-
-
Mandal, G.1
Wyllie, S.2
Singh, N.3
Sundar, S.4
Fairlamb, A.H.5
Chatterjee, M.6
-
59
-
-
4844227764
-
Antimicrobial reactive oxygen and nitrogen species: concepts and controversies
-
Fang F.C. Antimicrobial reactive oxygen and nitrogen species: concepts and controversies. Nat. Rev. Microbiol. 2 (2004) 820-832
-
(2004)
Nat. Rev. Microbiol.
, vol.2
, pp. 820-832
-
-
Fang, F.C.1
-
60
-
-
0031277625
-
Isolation of a nitric oxide synthase from the protozoan parasite, Leishmania donovani
-
Basu N.K., Kole L., Ghosh A., and Das P.K. Isolation of a nitric oxide synthase from the protozoan parasite, Leishmania donovani. FEMS Microbiol. Lett. 156 (1997) 43-47
-
(1997)
FEMS Microbiol. Lett.
, vol.156
, pp. 43-47
-
-
Basu, N.K.1
Kole, L.2
Ghosh, A.3
Das, P.K.4
-
61
-
-
33750224426
-
Phagocytosis of Leishmania donovani amastigotes is Rac1 dependent and occurs in the absence of NADPH oxidase activation
-
Lodge R., and Descoteaux A. Phagocytosis of Leishmania donovani amastigotes is Rac1 dependent and occurs in the absence of NADPH oxidase activation. Eur. J. Immunol. 36 (2006) 2735-2744
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 2735-2744
-
-
Lodge, R.1
Descoteaux, A.2
-
62
-
-
0031282556
-
Biochemical and genetic tests for inhibitors of Leishmania pteridine pathways
-
Hardy L.W., Matthews W., Nare B., and Beverley S.M. Biochemical and genetic tests for inhibitors of Leishmania pteridine pathways. Exp. Parasitol. 87 (1997) 157-169
-
(1997)
Exp. Parasitol.
, vol.87
, pp. 157-169
-
-
Hardy, L.W.1
Matthews, W.2
Nare, B.3
Beverley, S.M.4
-
63
-
-
40349108458
-
Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development
-
Cavazzuti A., Paglietti G., Hunter W.N., Gamarro F., Piras S., Loriga M., Allecca S., Corona P., McLuskey K., Tulloch L., Gibellini F., Ferrari S., and Costi M.P. Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development. Proc. Natl. Acad. Sci. USA 105 (2008) 1448-1453
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 1448-1453
-
-
Cavazzuti, A.1
Paglietti, G.2
Hunter, W.N.3
Gamarro, F.4
Piras, S.5
Loriga, M.6
Allecca, S.7
Corona, P.8
McLuskey, K.9
Tulloch, L.10
Gibellini, F.11
Ferrari, S.12
Costi, M.P.13
-
64
-
-
0027255738
-
Mechanisms of drug resistance in Leishmania
-
Ouellette M., and Papadopoulou B. Mechanisms of drug resistance in Leishmania. Parasitol. Today 9 (1993) 150-153
-
(1993)
Parasitol. Today
, vol.9
, pp. 150-153
-
-
Ouellette, M.1
Papadopoulou, B.2
-
65
-
-
0029056897
-
Antioxidative activity of 5,6,7,8-tetrahydrobiopterin and its inhibitory effect on paraquat-induced cell toxicity in cultured rat hepatocytes
-
Kojima S., Ona S., Iizuka I., Arai T., Mori H., and Kubota K. Antioxidative activity of 5,6,7,8-tetrahydrobiopterin and its inhibitory effect on paraquat-induced cell toxicity in cultured rat hepatocytes. Free Radic. Res. 23 (1995) 419-430
-
(1995)
Free Radic. Res.
, vol.23
, pp. 419-430
-
-
Kojima, S.1
Ona, S.2
Iizuka, I.3
Arai, T.4
Mori, H.5
Kubota, K.6
-
66
-
-
3242804442
-
Interference of 7,8-dihydroneopterin with peroxynitrite-mediated reactions
-
Oettl K., Greilberger J., Dikalov S., and Reibnegger G. Interference of 7,8-dihydroneopterin with peroxynitrite-mediated reactions. Biochem. Biophys. Res. Commun. 321 (2004) 379-385
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.321
, pp. 379-385
-
-
Oettl, K.1
Greilberger, J.2
Dikalov, S.3
Reibnegger, G.4
-
67
-
-
0026072572
-
Gene amplification in Leishmania
-
Beverley S.M. Gene amplification in Leishmania. Annu. Rev. Microbiol. 45 (1991) 417-444
-
(1991)
Annu. Rev. Microbiol.
, vol.45
, pp. 417-444
-
-
Beverley, S.M.1
-
68
-
-
0028822932
-
New mechanisms of drug resistance in parasitic protozoa
-
Borst P., and Ouellette M. New mechanisms of drug resistance in parasitic protozoa. Annu. Rev. Microbiol. 49 (1995) 427-460
-
(1995)
Annu. Rev. Microbiol.
, vol.49
, pp. 427-460
-
-
Borst, P.1
Ouellette, M.2
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