메뉴 건너뛰기




Volumn 36, Issue 10, 2006, Pages 2735-2744

Phagocytosis of Leishmania donovani amastigotes is Rac1 dependent and occurs in the absence of NADPH oxidase activation

Author keywords

Host pathogen interactions; Leishmania; Macrophages; Phagocytosis

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 6; IMMUNOGLOBULIN G; PROTEIN P47; PROTEIN P67; RAC1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; ZYMOSAN;

EID: 33750224426     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200636089     Document Type: Article
Times cited : (67)

References (51)
  • 1
    • 8644255770 scopus 로고    scopus 로고
    • Assembly of the phagocyte NADPH oxidase
    • Nauseef, W. M., Assembly of the phagocyte NADPH oxidase. Histochem, Cell. Biol. 2004. 122: 277-291.
    • (2004) Histochem. Cell. Biol. , vol.122 , pp. 277-291
    • Nauseef, W.M.1
  • 2
    • 0037108109 scopus 로고    scopus 로고
    • Current molecular models for NADPH oxidase regulation by Rac GTPase
    • Bokoch, G. M. and Diebold, B. A., Current molecular models for NADPH oxidase regulation by Rac GTPase. Blood 2002. 100: 2692-2696.
    • (2002) Blood , vol.100 , pp. 2692-2696
    • Bokoch, G.M.1    Diebold, B.A.2
  • 3
    • 0037248553 scopus 로고    scopus 로고
    • A novel assay system implicates Ptdlns(3,4)P(2), Ptdlns(3)P, and PKCδ in intracellular production of reactive oxygen species by the NADPH oxidase
    • Brown, G. E., Stewart, M. Q., Liu, H., Ha, V. L. and Yaffe, M. B., A novel assay system implicates Ptdlns(3,4)P(2), Ptdlns(3)P, and PKCδ in intracellular production of reactive oxygen species by the NADPH oxidase. Mol. Cell 2003. 11: 35-47.
    • (2003) Mol. Cell , vol.11 , pp. 35-47
    • Brown, G.E.1    Stewart, M.Q.2    Liu, H.3    Ha, V.L.4    Yaffe, M.B.5
  • 4
    • 0033557291 scopus 로고    scopus 로고
    • Macrophage microbicidal mechanisms in vivo: Reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani
    • Murray, H. W. and Nathan, C. F., Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani. J. Exp. Med. 1999. 189: 741-746.
    • (1999) J. Exp. Med. , vol.189 , pp. 741-746
    • Murray, H.W.1    Nathan, C.F.2
  • 5
    • 0019471126 scopus 로고
    • Susceptibility of Leishmania to oxygen intermediates and killing by normal macrophages
    • Murray, H. W., Susceptibility of Leishmania to oxygen intermediates and killing by normal macrophages. J. Exp. Med. 1981. 153: 1302-1315.
    • (1981) J. Exp. Med. , vol.153 , pp. 1302-1315
    • Murray, H.W.1
  • 6
    • 0026793462 scopus 로고
    • Metabolism and functions of trypanothione in the Kinetoplastida
    • Fairlamb, A. H. and Cerami, A., Metabolism and functions of trypanothione in the Kinetoplastida. Anna. Rev. Microbiol. 1992. 46: 695-729.
    • (1992) Anna. Rev. Microbiol. , vol.46 , pp. 695-729
    • Fairlamb, A.H.1    Cerami, A.2
  • 7
    • 0026693720 scopus 로고
    • Defective stimulus-response coupling in human monocytes infected with Leishmania donovani is associated with altered activation and translocation of protein kinase C
    • Olivier, M., Brownsey, R. W. and Reiner, N. E., Defective stimulus-response coupling in human monocytes infected with Leishmania donovani is associated with altered activation and translocation of protein kinase C. Proc. Natl. Acad. Sci. USA 1992. 89: 7481-7485.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7481-7485
    • Olivier, M.1    Brownsey, R.W.2    Reiner, N.E.3
  • 8
    • 28444478749 scopus 로고    scopus 로고
    • Leishmania pifanoi amastigotes avoid macrophage production of superoxide by inducing heme degradation
    • Pham, N. K, Mouriz, J. and Kima, P. E., Leishmania pifanoi amastigotes avoid macrophage production of superoxide by inducing heme degradation. Infect. Immun. 2005. 73: 8322-8333.
    • (2005) Infect. Immun. , vol.73 , pp. 8322-8333
    • Pham, N.K.1    Mouriz, J.2    Kima, P.E.3
  • 9
    • 0019978017 scopus 로고
    • Cell-mediated immune response in experimental visceral leishmaniasis. II. Oxygen-dependent killing of intracellular Leishmania donovani amastigotes
    • Murray, H. W., Cell-mediated immune response in experimental visceral leishmaniasis. II. Oxygen-dependent killing of intracellular Leishmania donovani amastigotes. J. Immunol. 1982. 129: 351-357.
    • (1982) J. Immunol. , vol.129 , pp. 351-357
    • Murray, H.W.1
  • 10
    • 0020607592 scopus 로고
    • Killing of intracellular Leishmania donovani by human mononuclear phagocytes. Evidence for oxygen-dependent and -independent leishmanicidal activity
    • Murray, H. W. and Cartelli, D. M., Killing of intracellular Leishmania donovani by human mononuclear phagocytes. Evidence for oxygen-dependent and -independent leishmanicidal activity. J. Clin. Invest. 1983. 72: 32-44.
    • (1983) J. Clin. Invest. , vol.72 , pp. 32-44
    • Murray, H.W.1    Cartelli, D.M.2
  • 11
    • 0021181879 scopus 로고
    • A study of the differential respiratory burst activity elicited by promastigotes and amastigotes of Leishmania donovani in murine resident peritoneal macrophages
    • Channon, J. Y., Roberts, M. B. and Blackwell, J. M., A study of the differential respiratory burst activity elicited by promastigotes and amastigotes of Leishmania donovani in murine resident peritoneal macrophages. Immunology 1984. 53: 345-355.
    • (1984) Immunology , vol.53 , pp. 345-355
    • Channon, J.Y.1    Roberts, M.B.2    Blackwell, J.M.3
  • 12
    • 0033943686 scopus 로고    scopus 로고
    • Nonopsonic phagocytosis of zymosan and Mycobacterium kansasii by CR3 (CD11b/CD18) involves distinct molecular determinants and is or is not coupled with NADPH oxidase activation
    • Le Cabec, V., Cols, C. and Maridonneau-Parini, I., Nonopsonic phagocytosis of zymosan and Mycobacterium kansasii by CR3 (CD11b/CD18) involves distinct molecular determinants and is or is not coupled with NADPH oxidase activation. Infect. Immun. 2000. 68: 4736-4745.
    • (2000) Infect. Immun. , vol.68 , pp. 4736-4745
    • Le Cabec, V.1    Cols, C.2    Maridonneau-Parini, I.3
  • 13
    • 0032935608 scopus 로고    scopus 로고
    • The mannose receptor mediates uptake of pathogenic and nonpathogenic mycobacteria and bypasses bactericidal responses in human macrophages
    • Astarie-Dequeker, C., N'Diaye, E. N., Le Cabec, V., Rittig, M. G., Prandi, J. and Maridonneau-Parini, I., The mannose receptor mediates uptake of pathogenic and nonpathogenic mycobacteria and bypasses bactericidal responses in human macrophages. Infect. Immun. 1999. 67: 469-477.
    • (1999) Infect. Immun. , vol.67 , pp. 469-477
    • Astarie-Dequeker, C.1    N'Diaye, E.N.2    Le Cabec, V.3    Rittig, M.G.4    Prandi, J.5    Maridonneau-Parini, I.6
  • 14
    • 0021854619 scopus 로고
    • Macrophage complement and lectin-like receptors bind Leishmania in the absence of serum
    • Blackwell, J. M., Ezekowitz, R. A., Roberts, M. B., Channon, J. Y., Sim, R. B. and Gordon, S., Macrophage complement and lectin-like receptors bind Leishmania in the absence of serum. J. Exp. Med. 1985. 162: 324-331.
    • (1985) J. Exp. Med. , vol.162 , pp. 324-331
    • Blackwell, J.M.1    Ezekowitz, R.A.2    Roberts, M.B.3    Channon, J.Y.4    Sim, R.B.5    Gordon, S.6
  • 15
    • 0034306013 scopus 로고    scopus 로고
    • Function of Rho family proteins in actin dynamics during phagocytosis and engulfment
    • Chimini, G. and Chavrier, P., Function of Rho family proteins in actin dynamics during phagocytosis and engulfment. NaL Cell Biol. 2000. 2: E191-E196.
    • (2000) Nat. Cell Biol. , vol.2
    • Chimini, G.1    Chavrier, P.2
  • 16
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville, S. and Hall, A., Rho GTPases in cell biology. Nature 2002. 420: 629-635.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 17
    • 1642462459 scopus 로고    scopus 로고
    • GTPases and reactive oxygen species: Switches for killing and signaling
    • Werner, E., GTPases and reactive oxygen species: switches for killing and signaling. J. Cell Sci. 2004. 117: 143-153.
    • (2004) J. Cell Sci. , vol.117 , pp. 143-153
    • Werner, E.1
  • 18
    • 0032573378 scopus 로고    scopus 로고
    • Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases
    • Caron, E. and Hall, A., Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science 1998. 282: 1717-1721.
    • (1998) Science , vol.282 , pp. 1717-1721
    • Caron, E.1    Hall, A.2
  • 19
    • 0032493491 scopus 로고    scopus 로고
    • A requirement for Arf6 in Fcγ receptor-mediated phagocytosis in macrophages
    • Zhang, Q., Cox, D., Tseng, C. C., Donaldson, J. G. and Greenberg, S., A requirement for Arf6 in Fcγ receptor-mediated phagocytosis in macrophages. J. Biol. Chem. 1998. 273: 19977-19981.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19977-19981
    • Zhang, Q.1    Cox, D.2    Tseng, C.C.3    Donaldson, J.G.4    Greenberg, S.5
  • 20
    • 0033512845 scopus 로고    scopus 로고
    • Arf6 is required for growth factor- and Rac-mediated membrane ruffling in macrophages at a stage distal to Rac membrane targeting
    • Zhang, Q., Calafat, J., Janssen, H. and Greenberg, S., Arf6 is required for growth factor- and Rac-mediated membrane ruffling in macrophages at a stage distal to Rac membrane targeting. Mol. Cell Biol. 1999.19: 8158-8168.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 8158-8168
    • Zhang, Q.1    Calafat, J.2    Janssen, H.3    Greenberg, S.4
  • 21
    • 0037477712 scopus 로고    scopus 로고
    • ADP ribosylation factor 6 is activated and controls membrane delivery during phagocytosis in macrophages
    • Niedergang, F., Colucci-Guyon, E., Dubois, T., Raposo, G. and Chavrier, P., ADP ribosylation factor 6 is activated and controls membrane delivery during phagocytosis in macrophages. J. Cell Biol. 2003. 161: 1143-1150.
    • (2003) J. Cell Biol. , vol.161 , pp. 1143-1150
    • Niedergang, F.1    Colucci-Guyon, E.2    Dubois, T.3    Raposo, G.4    Chavrier, P.5
  • 22
    • 27244452734 scopus 로고    scopus 로고
    • Leishmania donovani promastigotes induce periphagosomal F-actin accumulation through retention of the GTPase Cdc42
    • Lodge, R. and Descoteaux, A., Leishmania donovani promastigotes induce periphagosomal F-actin accumulation through retention of the GTPase Cdc42. Cell Microbiol. 2005. 7: 1647-1658.
    • (2005) Cell Microbiol. , vol.7 , pp. 1647-1658
    • Lodge, R.1    Descoteaux, A.2
  • 23
    • 0036070631 scopus 로고    scopus 로고
    • Opsonization modulates Rac-1 activation during cell entry by Leishmania amazonensis
    • Morehead, J., Coppens, I. and Andrews, N. W., Opsonization modulates Rac-1 activation during cell entry by Leishmania amazonensis. Infect. Immun. 2002. 70: 4571-4580.
    • (2002) Infect. Immun. , vol.70 , pp. 4571-4580
    • Morehead, J.1    Coppens, I.2    Andrews, N.W.3
  • 24
    • 0028100782 scopus 로고
    • Leishmania donovani-infected macrophages: Characterization of the parasitophorous vacuole and potential role of this organelle in antigen presentation
    • Lang, T., Hellio, R., Kaye, P. M. and Antoine, J. C., Leishmania donovani-infected macrophages: characterization of the parasitophorous vacuole and potential role of this organelle in antigen presentation. J. Cell Sci. 1994. 107: 2137-2150.
    • (1994) J. Cell Sci. , vol.107 , pp. 2137-2150
    • Lang, T.1    Hellio, R.2    Kaye, P.M.3    Antoine, J.C.4
  • 25
    • 0033788202 scopus 로고    scopus 로고
    • Macrophage subsets harbouring Leishmania donovani in spleens of infected BALB/c mice: Localization and characterization
    • Lang, T., Ave, P., Huerre, M., Milon, G. and Antoine, J. C., Macrophage subsets harbouring Leishmania donovani in spleens of infected BALB/c mice: localization and characterization. Cell Microbiol. 2000. 2: 415-430.
    • (2000) Cell Microbiol. , vol.2 , pp. 415-430
    • Lang, T.1    Ave, P.2    Huerre, M.3    Milon, G.4    Antoine, J.C.5
  • 27
    • 1842510009 scopus 로고    scopus 로고
    • The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly
    • Vilhardt, F. and Van Deurs, B., The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly. EMBO J. 2004. 23: 739-748.
    • (2004) EMBO J. , vol.23 , pp. 739-748
    • Vilhardt, F.1    Van Deurs, B.2
  • 29
    • 0037103252 scopus 로고    scopus 로고
    • Complement receptor 3 (CD11b/CD18) mediates type I and type II phagocytosis during nonopsonic and opsonic phagocytosis, respectively
    • Le Cabec, V., Carreno, S., Moisand, A., Bordier, C. and Maridonneau-Parini, I, Complement receptor 3 (CD11b/CD18) mediates type I and type II phagocytosis during nonopsonic and opsonic phagocytosis, respectively. J. Immunol. 2002. 169: 2003-2009.
    • (2002) J. Immunol. , vol.169 , pp. 2003-2009
    • Le Cabec, V.1    Carreno, S.2    Moisand, A.3    Bordier, C.4    Maridonneau-Parini, I.5
  • 31
    • 12844287455 scopus 로고    scopus 로고
    • Cdc42 and RhoB activation are required for mannose receptor-mediated phagocytosis by human alveolar macrophages
    • Zhang, J., Zhu, J., Bu, X., Cushion, M., Kinane, T. B., Avraham, H. and Koziel, H., Cdc42 and RhoB activation are required for mannose receptor-mediated phagocytosis by human alveolar macrophages. Mol. Biol. Cell. 2005. 16: 824-834.
    • (2005) Mol. Biol. Cell. , vol.16 , pp. 824-834
    • Zhang, J.1    Zhu, J.2    Bu, X.3    Cushion, M.4    Kinane, T.B.5    Avraham, H.6    Koziel, H.7
  • 33
    • 0027483033 scopus 로고
    • Comparison of receptors required for entry of Leishmania major amastigotes into macrophages
    • Guy, R. A. and Belosevic, M., Comparison of receptors required for entry of Leishmania major amastigotes into macrophages. Infect. Immun. 1993. 61: 1553-1558.
    • (1993) Infect. Immun. , vol.61 , pp. 1553-1558
    • Guy, R.A.1    Belosevic, M.2
  • 34
    • 0029585453 scopus 로고
    • The role of macrophage receptors in adhesion and uptake of Leishmania mexicana amastigotes
    • Peters, C., Aebischer, T., Stierhof, Y. D., Fuchs, M. and Overath, P., The role of macrophage receptors in adhesion and uptake of Leishmania mexicana amastigotes. J. Cell Sci. 1995. 108: 3715-3724.
    • (1995) J. Cell Sci. , vol.108 , pp. 3715-3724
    • Peters, C.1    Aebischer, T.2    Stierhof, Y.D.3    Fuchs, M.4    Overath, P.5
  • 35
    • 0034689062 scopus 로고    scopus 로고
    • Internalization of Leishmania mexicana complex amastigotes via the Fc receptor is required to sustain infection in murine cutaneous leishmaniasis
    • Kima, P. E., Constant, S. L., Hannum, L., Colmenares, M., Lee, K. S., Haberman, A. M., Shlomchik, M. J. et al., Internalization of Leishmania mexicana complex amastigotes via the Fc receptor is required to sustain Infection in murine cutaneous leishmaniasis. J. Exp. Med. 2000. 191: 1063-1068.
    • (2000) J. Exp. Med. , vol.191 , pp. 1063-1068
    • Kima, P.E.1    Constant, S.L.2    Hannum, L.3    Colmenares, M.4    Lee, K.S.5    Haberman, A.M.6    Shlomchik, M.J.7
  • 36
    • 16244378045 scopus 로고    scopus 로고
    • Interleukin 10- and Fcγ receptor-deficient mice resolve Leishmania mexicana lesions
    • Buxbaum, L. U. and Scott, P., Interleukin 10- and Fcγ receptor-deficient mice resolve Leishmania mexicana lesions. Infect. Immun. 2005. 73: 2101-2108.
    • (2005) Infect. Immun. , vol.73 , pp. 2101-2108
    • Buxbaum, L.U.1    Scott, P.2
  • 37
    • 18644364718 scopus 로고    scopus 로고
    • Control of infection with Leishmania major in susceptible BALB/c mice lacking the common γ-chain for FcR is associated with reduced production of IL- 10 and TGFβ by parasitized cells
    • Padigel, U. M. and Farrell, J. P., Control of infection with Leishmania major in susceptible BALB/c mice lacking the common γ-chain for FcR is associated with reduced production of IL- 10 and TGFβ by parasitized cells. J. Immunol. 2005. 174: 6340-6345.
    • (2005) J. Immunol. , vol.174 , pp. 6340-6345
    • Padigel, U.M.1    Farrell, J.P.2
  • 38
    • 31344442771 scopus 로고    scopus 로고
    • Uptake of Leishmania major by dendritic cells is mediated by Fcγ receptors and facilitates acquisition of protective immunity
    • Woelbing, F., Kostka, S. L., Moelle, K., Belkaid, Y., Sunderkoetter, C., Verbeek, S., Waisman, A. et al., Uptake of Leishmania major by dendritic cells is mediated by Fcγ receptors and facilitates acquisition of protective immunity. J. Exp. Med. 2006. 203: 177-188.
    • (2006) J. Exp. Med. , vol.203 , pp. 177-188
    • Woelbing, F.1    Kostka, S.L.2    Moelle, K.3    Belkaid, Y.4    Sunderkoetter, C.5    Verbeek, S.6    Waisman, A.7
  • 40
    • 23844543738 scopus 로고    scopus 로고
    • Leishmania donovani lipophosphoglycan disrupts phagosome microdomains in J774 macrophages
    • Dermine, J. F., Goyette, G., Houde, M., Turco, S. J. and Desjardins, M., Leishmania donovani lipophosphoglycan disrupts phagosome microdomains in J774 macrophages. Cell Microbiol. 2005. 7: 1263-1270.
    • (2005) Cell Microbiol. , vol.7 , pp. 1263-1270
    • Dermine, J.F.1    Goyette, G.2    Houde, M.3    Turco, S.J.4    Desjardins, M.5
  • 41
    • 0025808065 scopus 로고
    • Developmental changes in the glycosylated phosphatidylinositols of Leishmania donovani. Characterization of the promastigote and amastigote glycolipids
    • McConville, M. J. and Blackwell, J. M., Developmental changes in the glycosylated phosphatidylinositols of Leishmania donovani. Characterization of the promastigote and amastigote glycolipids. J. Biol. Chem. 1991. 266: 15170-15179.
    • (1991) J. Biol. Chem. , vol.266 , pp. 15170-15179
    • McConville, M.J.1    Blackwell, J.M.2
  • 42
    • 0038636239 scopus 로고    scopus 로고
    • Organ-specific and stage-dependent control of Leishmania major infection by inducible nitric oxide synthase and phagocyte NADPH oxidase
    • Blos, M., Schleicher, U., Soares Rocha, F. J., Meissner, U., Rollinghoff, M. and Bogdan, C., Organ-specific and stage-dependent control of Leishmania major infection by inducible nitric oxide synthase and phagocyte NADPH oxidase. Eur. J. Immunol. 2003. 33: 1224-1234.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1224-1234
    • Blos, M.1    Schleicher, U.2    Soares Rocha, F.J.3    Meissner, U.4    Rollinghoff, M.5    Bogdan, C.6
  • 43
    • 0020426315 scopus 로고
    • Host-parasite relationship in murine leishmaniasis: Pathophysiological and immunological changes
    • Reiner, N. E., Host-parasite relationship in murine leishmaniasis: pathophysiological and immunological changes. Infect. Immun. 1982. 38: 1223-1230.
    • (1982) Infect. Immun. , vol.38 , pp. 1223-1230
    • Reiner, N.E.1
  • 44
    • 0029015774 scopus 로고
    • The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF
    • Hill, C. S., Wynne, J. and Treisman, R., The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell 1995. 81: 1159-1170.
    • (1995) Cell , vol.81 , pp. 1159-1170
    • Hill, C.S.1    Wynne, J.2    Treisman, R.3
  • 45
    • 0030298138 scopus 로고    scopus 로고
    • Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade
    • Lamarche, N., Tapon, N., Stowers, L., Burbelo, P. D., Aspenstrom, P., Bridges, T., Chant, J. et al., Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade. Cell 1996. 87: 519-529.
    • (1996) Cell , vol.87 , pp. 519-529
    • Lamarche, N.1    Tapon, N.2    Stowers, L.3    Burbelo, P.D.4    Aspenstrom, P.5    Bridges, T.6    Chant, J.7
  • 46
    • 0028951905 scopus 로고
    • Overexpression of wild-type and mutant Arf1 and Arf6: Distinct perturbations of nonoverlapping membrane compartments
    • Peters, P. J., Hsu, V. W., Ooi, C. E., Finazzi, D., Teal, S. B., Oorschot, V., Donaldson, J. G. et al., Overexpression of wild-type and mutant Arf1 and Arf6: distinct perturbations of nonoverlapping membrane compartments. J. Cell Biol. 1995. 128: 1003-1017.
    • (1995) J. Cell Biol. , vol.128 , pp. 1003-1017
    • Peters, P.J.1    Hsu, V.W.2    Ooi, C.E.3    Finazzi, D.4    Teal, S.B.5    Oorschot, V.6    Donaldson, J.G.7
  • 47
    • 0030816319 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 regulates a novel plasma membrane recycling pathway
    • Radhakrishna, H. and Donaldson, J. G., ADP-ribosylation factor 6 regulates a novel plasma membrane recycling pathway. J. Cell Biol. 1997. 139: 49-61.
    • (1997) J. Cell Biol. , vol.139 , pp. 49-61
    • Radhakrishna, H.1    Donaldson, J.G.2
  • 48
    • 0018095849 scopus 로고
    • Increased superoxide anion production by immunologically activated and chemically elicited macrophages
    • Johnston, R. B., Jr., Godzik, C. A. and Cohn, Z. A., Increased superoxide anion production by immunologically activated and chemically elicited macrophages. J. Exp. Med. 1978. 148: 115-127
    • (1978) J. Exp. Med. , vol.148 , pp. 115-127
    • Johnston Jr., R.B.1    Godzik, C.A.2    Cohn, Z.A.3
  • 49
    • 0027172753 scopus 로고
    • Leishmania major: Respiratory burst response of infected murine macrophages treated with paromomycin
    • Gueron, E., Isakov, N. and el-On, J., Leishmania major: respiratory burst response of infected murine macrophages treated with paromomycin. Exp. Parasitol. 1993. 76: 371-376.
    • (1993) Exp. Parasitol. , vol.76 , pp. 371-376
    • Gueron, E.1    Isakov, N.2    el-On, J.3
  • 50
    • 0032484218 scopus 로고    scopus 로고
    • Protein kinase Cα modulates lipopolysaccharide-induced functions in a murine macrophage cell line
    • St-Denis, A., Chano, F., Tremblay, P., St-Pierre, Y. and Descoteaux, A., Protein kinase Cα modulates lipopolysaccharide-induced functions in a murine macrophage cell line. J. Biol. Chem. 1998. 273: 32787-32792.
    • (1998) J. Biol. Chem. , vol.273 , pp. 32787-32792
    • St-Denis, A.1    Chano, F.2    Tremblay, P.3    St-Pierre, Y.4    Descoteaux, A.5
  • 51
    • 27144477318 scopus 로고    scopus 로고
    • Cutting edge: MyD88 controls phagocyte NADPH oxidase function and killing of gram-negative bacteria
    • Laroux, F. S., Romero, X., Wetzler, L., Engel, P. and Terhorst, C., Cutting edge: MyD88 controls phagocyte NADPH oxidase function and killing of gram-negative bacteria. J. Immunol. 2005. 175: 5596-5600.
    • (2005) J. Immunol. , vol.175 , pp. 5596-5600
    • Laroux, F.S.1    Romero, X.2    Wetzler, L.3    Engel, P.4    Terhorst, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.