Conformational dynamics of the flexible catalytic loop in Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase

Chemical Biology and Drug Design

Volumn 73, Issue 1, 2009, Pages 26-38

  Williams, Sarah L ^a   Andrew McCammon, J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Molecular modelling; Protein structure; Structure based drug design

Indexed keywords

1 DEOXY DEXTRO XYLULOSE 5 PHOSPHATE REDUCTOISOMERASE; BACTERIAL ENZYME; FOSMIDOMYCIN; ISOMERASE; MANGANESE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME CONFORMATION; MOLECULAR DYNAMICS; MOLECULAR MODEL; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL;

ALDOSE-KETOSE ISOMERASES; CATALYTIC DOMAIN; CLUSTER ANALYSIS; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MYCOBACTERIUM TUBERCULOSIS; OXIDOREDUCTASES; PENTOSEPHOSPHATES; PRINCIPAL COMPONENT ANALYSIS; PROTEIN CONFORMATION;

CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 58149092426     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2008.00749.x     Document Type: Article

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