Crystal structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase, a crucial enzyme in the non-mevalonate pathway of isoprenoid biosynthesis

Journal of Biological Chemistry

Volumn 277, Issue 7, 2002, Pages 5378-5384

  Reuter, Klaus ^a   Sanderbrand, Silke ^a   Jomaa, Hassan ^a   Wiesner, Jochen ^a   Steinbrecher, Irina ^a   Beck, Ewald ^a   Hintz, Martin ^a   Klebe, Gerhard ^a   Stubbs, Milton T ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CONFORMATIONS; CRYSTAL STRUCTURE; DIMERIZATION; MONOMERS; POSITIVE IONS;

HOMODIMERS;

ENZYMES;

1 DEOXY DEXTRO XYLULOSE 5 PHOSPHATE REDUCTOISOMERASE; ISOPRENOID; MEVALONIC ACID; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; DINUCLEOTIDE REPEAT; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SYNTHESIS; GENE REARRANGEMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING; TARGET CELL;

ALDOSE-KETOSE ISOMERASES; ASPARTIC ACID; BINDING SITES; CATIONS; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ESCHERICHIA COLI; GLUTAMIC ACID; LIGANDS; MODELS, CHEMICAL; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; OXIDOREDUCTASES; POLYISOPRENYL PHOSPHATES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY;

EID: 0037085356     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M109500200     Document Type: Article

References (26)