Daxx inhibits stress-induced apoptosis in cardiac myocytes

Redox Report

Volumn 13, Issue 6, 2008, Pages 263-270

  Zobalova, Renata ^a,b   Swettenham, Emma ^a   Chladova, Jaromira ^b   Dong, Lan Feng ^a   Neuzil, Jiri ^a,b  

^a GRIFFITH UNIVERSITY   (Australia)

^b INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

Author keywords

Apoptosis; Cardiomyocytes; Daxx; Oxidative stress

Indexed keywords

DAXX PROTEIN; DJ 1 PROTEIN; PLASMID DNA; SMALL INTERFERING RNA;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL HYPOXIA; CELL PROTECTION; CELL STIMULATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CELLULAR STRESS RESPONSE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; GENE DELIVERY SYSTEM; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HEART MUSCLE CELL; HUMAN; HUMAN CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; REGULATORY MECHANISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL LINE; CELL NUCLEUS; CYTOPLASM; FLOW CYTOMETRY; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICROSCOPY, CONFOCAL; MICROTUBULE-ASSOCIATED PROTEINS; MYOCYTES, CARDIAC; NUCLEAR PROTEINS; ONCOGENE PROTEINS; RATS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 58049192948     PISSN: 13510002     EISSN: None     Source Type: Journal    
DOI: 10.1179/135100008X308975     Document Type: Article

References (41)

1. Yellon DM, Hausenloy DJ. Myocardial reperfusion injury. N Engl J Med 2000; 357: 1121-1135.
2. Neuzil J, Rayner BS, Lowe HC, Witting PK. Oxidative stress in myocardial ischemia reperfusion injury: A renewed focus on a long- standing area of research. Redox Report 2005; 10: 185-195.
3. α0 are target proteins of reactive oxygen species. Nature 2000; 408: 492-495.
4. Kim KS, Hwang HA, Chae SK, Ha H, Kwon KS. Upregulation of Daxx mediates apoptosis in response to oxidative stress. J Cell Biochem 2005; 96: 330-338.
5. Neuzil J, Widen C, Gellert N et al. Mitochondria transmit apoptotic signals in cardiomyocyte-like cells and isolated hearts exposed to experimental ischemia-reperfusion injury. Redox Report 2007; 12: 148-162.
6. Chandra J, Samali A, Orrenius S. Triggering and modulation of apoptosis by oxidative stress. Free Radic Biol Med 2000; 29: 323-333.
7. Mascareno E, El-Shafei M, Maulik N, Sato M, Guo Y, Das DK, Siddiqui MA. JAK/STAT signaling is associated with cardiac dysfunction during ischemia and reperfusion. Circulation 2001; 104: 325-329
8. Song JJ, Lee YJ. Catalase, but not MnSOD, inhibits glucose deprivation-activated ASK1-MEK-MAPK signal transduction pathway and prevents relocalization of Daxx: Hydrogen peroxide as a major second messenger of metabolic oxidative stress. J Cell Biochem 2003; 90: 304-314.
9. Yang X, Khosravi-Far R, Chang HY, Baltimore D. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 1997; 89: 1067-1076.
10. Chang HY, Nishitoh H, Yang X, Ichijo H, Baltimore D. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adaptor protein Daxx. Science 1998; 281: 1860-1863.
11. Zhong S, Salomoni P, Ronchetti S, Guo A, Ruggero D, Pandolfi PP. Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis. J Exp Med 2000; 191: 631-640.
12. Ishov AM, Sotnikov AG, Negorev D et al. PML is critical for ND10 formation and recruits the PML-interacting protein Daxx to this nuclear structure when modified by SUMO-1. J Cell Biol 1999; 147: 221-234.
13. Li H, Leo C, Zhu J, Wu X, O'Neil J, Park EJ, Chen JD. Sequestration and inhibition of Daxx-mediated transcriptional repression by PML. Mol Cell Biol 2000; 20: 1784-1796.
14. Salomoni P, Pandolfi PP. The role of PML in tumor suppression. Cell 2000; 108: 165-170.
15. Perlman R, Schiemann WP, Brooks MW, Lodish HF, Weinberg RA. TGF-β-induced apoptosis is mediated by the adaptor protein Daxx that facilitates JNK activation. Nat Cell Biol 2001; 3: 708-714.
16. Khelifi AF, D'Alcontres MS, Salomoni P. Daxx is required for stress-induced cell death and JNK activation. Cell Death Differ 2005; 12: 724-733.
17. Chang HY, Yang X, Baltimore D. Dissecting Fas signaling with an altered-specificity death-domain mutant: Requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation. Proc Natl Acad Sci USA 1999; 281: 1860-1863.
18. Michaelson JS, Bader D, Kuo F, Kozak C, Leder P. Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development. Genes Dev 1999; 13: 1918-1923
19. Chen LY, Chen JD. Daxx silencing sensitizes cells to multiple apoptotic pathways. Mol Cell Biol 2003; 23: 7108-7121.
20. Michaelson JS, Leder P. RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX. J Cell Sci 2003; 116: 345-352.
21. Ko YG, Kang YS, Park H et al. Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm. J Biol Chem 2001; 276: 39103-39106.
22. Lehembre F, Muller S, Pandolfi PP, Dejean A. Regulation of Pax3 transcriptional activity by SUMO-1-modofied PML. Oncogene 2001; 19: 1-9.
23. Kiriakidou M, Driscoll DA, Lopez-Guisa JM, Strauss JF. Cloning and expression of primate Daxx cDNAs and mapping of the human gene to chromosome 6p21.3 in the MHC region. DNA Cell Biol 1997; 16: 1289-1298.
24. Michaelson JS. The Daxx enigma. Apoptosis 2000; 5: 217-220.
25. Kim EJ, Park JS, Um SJ. Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PML. Nucleic Acids Res 2003; 31: 5356-5367.
26. Krammer PH. CD95(APO-1/Fas)-mediated apoptosis: Live and let die. Adv Immunol 1999; 71: 163-210.
27. Hsu H, Xiong J, Goeddel DV. The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell 1995; 81: 495-504.
28. Zhang J, Gao JX, Salojin K et al. Regulation of fas ligand expression during activation-induced cell death in T cells by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase. J Exp Med 2000; 191: 1017-1030.
29. Curtin JF, Cotter TG. Live and let die: Regulatory mechanisms in Fas-mediated apoptosis. Cell Signal 2003; 15: 983-992
30. Claycomb WC, Lanson NA, Stallworth et al. HL-1 cells: A cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proc Natl Acad Sci USA 1998; 95: 2979-2984.
31. Dong LF, Swettenham E, Eliasson J et al. Vitamin E analogs inhibit angiogenesis by selective apoptosis induction in proliferating endothelial cells: The role of oxidative stress. Cancer Res 2007; 67: 11906-11913.
32. Stapelberg M, Gellert N, Swettenham E et al. α-Tocopheryl succinate inhibits malignant mesothelioma by disrupting the FGF autocrine loop: The role of oxidative stress. J Biol Chem 2005; 280: 25369-25376.
33. Weber T, Dalen H, Andera L et al. Mitochondria play a central role in apoptosis induced by α-tocopheryl succinate, an agent with anticancer activity. Biochemistry 2003; 42: 4277-4291
34. Yaniv G, Shilkrut M, Larisch S, Binah O. Hydrogen peroxide predisposes neonatal rat ventricular myocytes to Fas-mediated apoptosis. Biochem Biophys Res Commun 2005; 336: 740-746.
35. Jung YS, Kim HY, Lee YJ, Kim E. Subcellular localization of Daxx determines its opposing functions in ischemic cell death. FEBS Lett 2007; 581: 843-852.
36. Roubille F, Combes S, Leal-Sanchez J et al. Myocardial expression of a dominant-negative form of Daxx decreases infarct size and attenuates apoptosis in an in vivo mouse model of ischemia/ reperfusion injury. Circulation 2007, 116: 2709-2717.
37. Witting PK, Liao WQ, Harris MJ, Neuzil J. Expression of wild-type and the Y103F variant of human myoglobin in H9c2 myocyte-like cells enhances toxicity toward added hydrogen peroxide. Biochem Biophys Res Commun 2006; 348: 485-493.
38. Chandel NS, Maltepe E, Goldwasser E, Mathieu CE, Simon MC, Schumacker PT. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proc Natl Acad Sci USA 1998; 95: 11715-11720.
39. 2 sensing. Science 2001; 292: 464-468.
40. Dawson TM, Dawson VL. Molecular pathways of neurodegeneration in Parkinson's disease. Science 2003; 302: 819-822.
41. Junn E, Taniguchi H, Jeong BS, Zhao X, Ichijo H, Mouradian MM. Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death. Proc Natl Acad Sci USA 2005; 102: 9691-9966.