The RhoGDI-α/JNK signaling pathway plays a significant role in mycophenolic acid-induced apoptosis in an insulin-secreting cell line

Cellular Signalling

Volumn 21, Issue 2, 2009, Pages 356-364

  Park, Yun Jong ^a   Ahn, Hyung Joon ^a,b   Chang, Hye Kyung ^c   Kim, Joon Ye ^a,d   Huh, Kyu Ha ^a,c   Kim, Myoung Soo ^a,c   Kim, Yu Seun ^a,c,d  

^a Yonsei University College of Medicine   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

^d Yonsei University   (South Korea)

Author keywords

Apoptosis; Insulin secreting cells; JNK; Mycophenolic acid; RhoGDI

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CASPASE INHIBITOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE; GUANOSINE TRIPHOSPHATE; INSULIN; MYCOPHENOLIC ACID; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR ALPHA; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ELECTROPHORESIS; ENZYME ACTIVATION; INSULIN RELEASE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; RAT; SIGNAL TRANSDUCTION;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; CASPASE 3; CELL LINE; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; INSULIN-SECRETING CELLS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MYCOPHENOLIC ACID; PROTEOMICS; RATS; SIGNAL TRANSDUCTION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 57649202568     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2008.11.009     Document Type: Article

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