Rho-GDP dissociation inhibitor alpha downregulated by low shear stress promotes vascular smooth muscle cell migration and apoptosis: A proteomic analysis

Cardiovascular Research

Volumn 80, Issue 1, 2008, Pages 114-122

  Qi, Ying Xin ^a   Qu, Ming Juan ^a   Long, Ding Kun ^a   Liu, Bo ^a   Yao, Qing Ping ^a   Chien, Shu ^a,b   Jiang, Zong Lai ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Migration; Rho GDI ; Shear stress; Vascular smooth muscle cells

Indexed keywords

GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; PROTEIN KINASE B; RAC1 PROTEIN; RHO GUANOSINE DIPHOSPHATE BINDING PROTEIN DISSOCIATION INHIBITOR ALPHA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; APOPTOSIS; ARTICLE; CELL ACTIVITY; CELL CULTURE; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; ELECTROPHORESIS; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENETIC TRANSFECTION; MALE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR MECHANICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEOMICS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SHEAR STRESS; SPRAGUE DAWLEY RAT; TWO DIMENSIONAL ELECTROPHORESIS; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; AORTA, THORACIC; APOPTOSIS; CELL MOVEMENT; DOWN-REGULATION; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; MALE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTEOMICS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 51749088177     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvn158     Document Type: Article

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