Ras activation in response to lysophosphatidic acid requires a permissive input from the epidermal growth factor receptor

Biochemical Journal

Volumn 376, Issue 3, 2003, Pages 571-576

  Rubio, Ignacio ^a   Rennert, Knut ^a   Wittig, Ute ^a   Wetzker, Reinhard ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Epidermal growth factor receptor (EGFR); Lysophosphatidic acid (LPA); Nucleotide exchange; Pertussis (PTX) toxin; Ras; Transactivation

Indexed keywords

CHEMICAL ACTIVATION; GROWTH KINETICS;

EPIDERMAL GROWTH FACTOR RECEPTORS (EGFR); NUCLEOTIDE EXCHANGE;

BIOCHEMISTRY;

4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 6,7 DIMETHOXY 2 PHENYLQUINOXALINE; EPIDERMAL GROWTH FACTOR RECEPTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LYSOPHOSPHATIDIC ACID; PERTUSSIS TOXIN; PLATELET DERIVED GROWTH FACTOR RECEPTOR BLOCKING AGENT; RAS PROTEIN; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN COS7; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; IMMUNOPRECIPITATION; NONHUMAN; NUCLEOTIDE BINDING SITE; NUCLEOTIDE TRANSPORT; PRIORITY JOURNAL; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION;

ANIMALS; COS CELLS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANINE NUCLEOTIDES; LYSOPHOSPHOLIPIDS; PERTUSSIS TOXIN; PROTO-ONCOGENE PROTEINS P21(RAS); RECEPTOR, EPIDERMAL GROWTH FACTOR;

ANIMALIA;

EID: 0346725911     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031410     Document Type: Article

References (42)

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