Enhancement by grapefruit juice of morphine antinociception

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 12, 2008, Pages 2338-2341

  Okura, Takashi ^a,b   Ozawa, Tadahiro ^a   Yoshihiko, I T O ^a   Kimura, Midori ^a   Kagawa, Yoshiyuki ^a   Yamada, Shizuo ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

Author keywords

Grapefruit juice; Microdialysis; Morphine; Tolerance

Indexed keywords

GLYCOPROTEIN P; MORPHINE; QUINIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG EFFECT; DRUG POTENTIATION; DRUG TOLERANCE; FOOD DRUG INTERACTION; GRAPEFRUIT JUICE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE ABSORPTION; MALE; MICRODIALYSIS; MORPHINE TOLERANCE; NONHUMAN; RAT; REPEATED DRUG DOSE; SPRAGUE DAWLEY RAT; TAIL FLICK TEST;

ALGORITHMS; ANALGESICS, OPIOID; ANIMALS; AREA UNDER CURVE; BEVERAGES; CITRUS PARADISI; DRUG SYNERGISM; DRUG TOLERANCE; INTESTINAL ABSORPTION; MALE; MICRODIALYSIS; MORPHINE; P-GLYCOPROTEIN; PAIN MEASUREMENT; QUINIDINE; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME;

EID: 57349145767     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.2338     Document Type: Article

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