Effects of glycogen synthase kinase 3β and cyclin-dependent kinase 5 inhibitors on morphine-induced analgesia and tolerance in rats

Journal of Pharmacology and Experimental Therapeutics

Volumn 319, Issue 2, 2006, Pages 832-839

  Parkitna, Jan Rodriguez ^a,b   Obara, Ilona ^a   Wawrzczak Bargiela, Agnieszka ^a   Makuch, Wioletta ^a   Przewlocka, Barbara ^a   Przewlocki, Ryszard ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; 6 BROMOINDIRUBIN 3' OXIME; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; MORPHINE; OPIATE RECEPTOR; ROSCOVITINE; UNCLASSIFIED DRUG;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG TOLERANCE; MALE; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SPINAL CORD; TAIL FLICK TEST;

ANALGESIA; ANALGESICS, OPIOID; ANIMALS; CYCLIN-DEPENDENT KINASE 5; DOPAMINE AND CAMP-REGULATED PHOSPHOPROTEIN 32; DRUG TOLERANCE; GLYCOGEN SYNTHASE KINASE 3; INDOLES; MALE; MALEIMIDES; MORPHINE; PAIN THRESHOLD; RATS; RATS, WISTAR; SPINAL CORD;

EID: 33751176293     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.107581     Document Type: Article

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